Joseph H Lee

Joseph H Lee

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Joseph H Lee

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A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Metabolism 2019 May 30;94:28-38. Epub 2019 Jan 30.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Departments of Medicine and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.01.010DOI Listing
May 2019

Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools.

Front Genet 2019 3;10:239. Epub 2019 Apr 3.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.

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https://www.frontiersin.org/article/10.3389/fgene.2019.00239
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http://dx.doi.org/10.3389/fgene.2019.00239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456789PMC
April 2019

Reply.

Ophthalmology 2019 Feb;126(2):e12-e13

Department of Ophthalmology, Columbia University, New York, New York.

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http://dx.doi.org/10.1016/j.ophtha.2018.08.027DOI Listing
February 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.

Authors:
Paul S de Vries Michael R Brown Amy R Bentley Yun J Sung Thomas W Winkler Ioanna Ntalla Karen Schwander Aldi T Kraja Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Xuan Deng Rajkumar Dorajoo Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Evangelos Evangelou Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Joseph H Lee Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Muhammad Riaz M Abdullah Said Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Yajuan Wang Erin B Ware Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Christie Ballantyne Eric Boerwinkle Ulrich Broeckel Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Ulf de Faire Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Jingzhong Ding Anna F Dominiczak Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul Virginia Fisher Terrence Forrester Oscar H Franco Yechiel Friedlander Mohsen Ghanbari Franco Giulianini Hans J Grabe Megan L Grove C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson Barbara V Howard M Arfan Ikram David R Jacobs Craig Johnson Jost Bruno Jonas Candace M Kammerer Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Heikki A Koistinen Ivana Kolcic Charles Kooperberg Jose E Krieger Steve B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Rozenn N Lemaitre Yize Li Jingjing Liang Jianjun Liu Kiang Liu Marie Loh Tin Louie Reedik Mägi Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Thomas H Mosley Kenneth J Mukamal Mike A Nalls Matthias Nauck Christopher P Nelson Nona Sotoodehnia Jeff R O'Connell Nicholette D Palmer Raha Pazoki Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Leslie J Raffel Olli T Raitakari Alex P Reiner Treva K Rice Stephen S Rich Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Nicholas Tan Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Diana van Heemst Dragana Vuckovic Melanie Waldenberger Lihua Wang Yujie Wang Zhe Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Markku Laakso Karin Leander Terho Lehtimäki Patrik K E Magnusson Brenda Penninx Alexandre C Pereira Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Wei Zheng Paul Elliott Kari E North Claude Bouchard Michele K Evans Vilmundur Gudnason Ching-Ti Liu Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Sharon L R Kardia Xiaofeng Zhu Charles N Rotimi Dennis O Mook-Kanamori Myriam Fornage Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Jingmin Liu Jerome I Rotter W James Gauderman Michael A Province Patricia B Munroe Kenneth Rice Daniel I Chasman L Adrienne Cupples Dabeeru C Rao Alanna C Morrison

Am J Epidemiol 2019 Jan 29. Epub 2019 Jan 29.

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas.

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https://academic.oup.com/aje/advance-article/doi/10.1093/aje
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http://dx.doi.org/10.1093/aje/kwz005DOI Listing
January 2019

Association between Atmospheric Particulate Pollutants and Mortality for Cardio-Cerebrovascular Diseases in Chinese Korean Population: A Case-Crossover Study.

Int J Environ Res Public Health 2018 12 12;15(12). Epub 2018 Dec 12.

School of Public Health, Medical College of Qingdao University, Qingdao 266021, Shandong Province, China.

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http://dx.doi.org/10.3390/ijerph15122835DOI Listing
December 2018

Mystery of the high chlorine consumption in disinfecting a chemically enhanced primary saline sewage.

Water Res 2018 11 14;145:181-189. Epub 2018 Aug 14.

Department of Civil and Environmental Engineering, Hong Kong University of Science and Technology, Hong Kong, China.

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https://linkinghub.elsevier.com/retrieve/pii/S00431354183065
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http://dx.doi.org/10.1016/j.watres.2018.08.031DOI Listing
November 2018

An improved statistical model for taxonomic assignment of metagenomics.

BMC Genet 2018 10 29;19(1):98. Epub 2018 Oct 29.

Sergievsky Center, Taub Institute, and Departments of Epidemiology and Neurology, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1186/s12863-018-0680-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206629PMC
October 2018

Risk Factors for Orthostatic Hypotension: Differences Between Elderly Men and Women.

Am J Hypertens 2018 Jun;31(7):797-803

Laboratory of Neurosciences, School of Medicine and Institute for Biological Research, University of Zulia, Zulia, Venezuela.

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http://dx.doi.org/10.1093/ajh/hpy050DOI Listing
June 2018

Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease.

Cell Rep 2018 Jun;23(10):2967-2975

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040810PMC
June 2018

Incidence of dementia in elderly Latin Americans: Results of the Maracaibo Aging Study.

Alzheimers Dement 2018 02 21;14(2):140-147. Epub 2017 Sep 21.

Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA; Department of Social Medicine, Psychiatry and Neurology, National and Kapodestrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1016/j.jalz.2017.06.2636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803319PMC
February 2018

Tracking major endocrine disruptors in coastal waters using an integrative approach coupling field-based study and hydrodynamic modeling.

Environ Pollut 2018 Feb 5;233:387-394. Epub 2017 Nov 5.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China; State Key Laboratory in Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02697491173139
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http://dx.doi.org/10.1016/j.envpol.2017.10.086DOI Listing
February 2018

Epidemiology of estrogen and dementia in women with Down syndrome.

Free Radic Biol Med 2018 01 31;114:62-68. Epub 2017 Aug 31.

Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748249PMC
January 2018

Ultra-rare mutations in segregate in Caribbean Hispanic families with Alzheimer disease.

Neurol Genet 2017 Oct 24;3(5):e178. Epub 2017 Aug 24.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain (B.N.V., G.T., R. Lefort, P.L.D.J., S.B., D.R.-D., J.H.L., R.C., R. Lantigua, R.M.); Gertrude H. Sergievsky Center (B.N.V., G.T., S.B., D.R.-D., J.H.L., R.C., R.M.); Department of Neurology (P.L.D.J., S.B., R.M.), Department of Psychiatry (R.M.), Department of Systems Biology (B.N.V.), Department of Medicine (R. Lantigua), and Department of Pathology and Cell Biology (R. Lefort, P.L.N.), College of Physicians and Surgeons, Columbia University, New York Presbyterian Hospital; Department of Epidemiology (J.H.L., R.M.), School of Public Health, Columbia University, New York; Tanz Centre for Research in Neurodegenerative Diseases (E.R., P.S.G.-H.) and Department of Medicine (E.R., P.S.G.-H.), University of Toronto, Krembil Discovery Tower, ON, Canada; Department of Clinical Neurosciences (P.S.G.-H.), Cambridge Institute for Medical Research, University of Cambridge, UK; Rush Alzheimer's Disease Center (L.Y., D.A.B.), Rush University Medical Center, Chicago, IL; Program in Medical and Population Genetics (P.L.D.J.), Broad Institute, Cambridge, MA; and School of Medicine (M.M.), Mother and Teacher Pontifical Catholic University, Santiago, Dominican Republic.

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http://dx.doi.org/10.1212/NXG.0000000000000178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570674PMC
October 2017

Short telomere length is associated with renal impairment in Japanese subjects with cardiovascular risk.

PLoS One 2017 25;12(4):e0176138. Epub 2017 Apr 25.

Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176138PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404870PMC
September 2017

Candidate gene analysis for Alzheimer's disease in adults with Down syndrome.

Neurobiol Aging 2017 08 3;56:150-158. Epub 2017 May 3.

Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Taub Institute, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Epidemiology, School of Public Health, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603247PMC
August 2017

Mediterranean diet and leukocyte telomere length in a multi-ethnic elderly population.

Age (Dordr) 2015 8;37(2):24. Epub 2015 Mar 8.

The Taub Institute for Research in Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, 622 W 168th St., P&S #16, New York, NY, 10032, USA.

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http://dx.doi.org/10.1007/s11357-015-9758-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352412PMC
February 2016

Gene-wise association of variants in four lysosomal storage disorder genes in neuropathologically confirmed Lewy body disease.

PLoS One 2015 1;10(5):e0125204. Epub 2015 May 1.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, United States of America; Gertrude H. Sergievsky Center, Columbia University, New York, New York, United States of America; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America; Center for Human Genetics, Columbia University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125204PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416714PMC
January 2016

Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.

Neurobiol Aging 2015 Oct 19;36(10):2907.e1-10. Epub 2015 Jun 19.

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA; G.H. Sergievsky Center, New York, NY, USA; Department of Epidemiology, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562880PMC
October 2015

Heritability of telomere length in a study of long-lived families.

Neurobiol Aging 2015 Oct 18;36(10):2785-90. Epub 2015 Jun 18.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA; Gertrude H. Sergievsky Center, Columbia University Medical Center, New York, NY, USA; Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562863PMC
October 2015

Genetic Modifiers of Age at Onset in Carriers of the G206A Mutation in PSEN1 With Familial Alzheimer Disease Among Caribbean Hispanics.

JAMA Neurol 2015 Sep;72(9):1043-51

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York2Gertrude H. Sergievsky Center, Columbia University, New York, New York3Department of Epidemiology, School of Public Health, Columbia Univer.

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http://dx.doi.org/10.1001/jamaneurol.2015.1424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010776PMC
September 2015

Inbreeding among Caribbean Hispanics from the Dominican Republic and its effects on risk of Alzheimer disease.

Genet Med 2015 Aug 13;17(8):639-43. Epub 2014 Nov 13.

1] The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA [2] The Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA [3] Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA [4] Department of Neurology, Columbia University, New York, New York, USA [5] Department of Psychiatry, School of Public Health, Columbia University, New York, New York, USA.

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https://ncrad.iu.edu/docs/Publications/32_Vardarajan_2014.pd
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http://www.nature.com/doifinder/10.1038/gim.2014.161
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http://dx.doi.org/10.1038/gim.2014.161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430451PMC
August 2015

F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.

Ann Clin Transl Neurol 2015 Aug 18;2(8):810-20. Epub 2015 Jun 18.

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, School of Public Health, Columbia University New York, New York ; The Gertrude H. Sergievsky Center, School of Public Health, Columbia University New York, New York ; Department of Neurology, Columbia University New York, New York ; Department of Psychiatry, School of Public Health, Columbia University New York, New York ; Department of Epidemiology, School of Public Health, Columbia University New York, New York.

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http://dx.doi.org/10.1002/acn3.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554442PMC
August 2015

Coding mutations in SORL1 and Alzheimer disease.

Ann Neurol 2015 Feb;77(2):215-27

Taub Institute for Research on Alzheimer's Disease and the Aging Brain; Gertrude H. Sergievsky Center, Columbia University, New York, NY.

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http://dx.doi.org/10.1002/ana.24305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367199PMC
February 2015

An integrated environmental risk assessment and management framework for enhancing the sustainability of marine protected areas: the Cape d'Aguilar Marine Reserve case study in Hong Kong.

Sci Total Environ 2015 Feb 15;505:269-81. Epub 2014 Oct 15.

Department of Civil and Environmental Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.

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http://dx.doi.org/10.1016/j.scitotenv.2014.09.088DOI Listing
February 2015

Environmental fate and ecological risks of nonylphenols and bisphenol A in the Cape D'Aguilar Marine Reserve, Hong Kong.

Mar Pollut Bull 2015 Feb 2;91(1):128-38. Epub 2015 Jan 2.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.marpolbul.2014.12.017DOI Listing
February 2015

Estrogen receptor β variants modify risk for Alzheimer's disease in a multiethnic female cohort.

J Alzheimers Dis 2014 ;40(1):83-93

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA Center for Human Genetics, College of Physicians & Surgeons, Columbia University, New York, NY, USA Department of Pathology and Cell Biology, College of Physicians & Surgeons, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.3233/JAD-130551DOI Listing
October 2014

Disease-related mutations among Caribbean Hispanics with familial dementia.

Mol Genet Genomic Med 2014 Sep 4;2(5):430-7. Epub 2014 Jun 4.

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University New York, New York ; The Gertrude H. Sergievsky Center, Columbia University New York, New York ; The Department of Epidemiology, School of Public Health, Columbia University New York, New York ; The Department of Neurology, Columbia University New York, New York ; The Department of Psychiatry, Columbia University New York, New York.

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http://doi.wiley.com/10.1002/mgg3.85
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http://dx.doi.org/10.1002/mgg3.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190878PMC
September 2014

The occurrence and ecological risks of endocrine disrupting chemicals in sewage effluents from three different sewage treatment plants, and in natural seawater from a marine reserve of Hong Kong.

Mar Pollut Bull 2014 Aug 17;85(2):352-62. Epub 2014 Mar 17.

The Swire Institute of Marine Science and School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China. Electronic address:

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http://files.kutassunk.webnode.hu/200000016-4447845435/xu_li
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http://linkinghub.elsevier.com/retrieve/pii/S0025326X1400125
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http://dx.doi.org/10.1016/j.marpolbul.2014.02.029DOI Listing
August 2014

Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.

Front Genet 2013 17;4:310. Epub 2014 Jan 17.

Sergievsky Center, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Taub Institute, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Department of Epidemiology, School of Public Health, Columbia University New York, NY, USA ; Department of Neurology, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Department of Psychiatry, College of Physicians and Surgeons, Columbia University New York, NY, USA.

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http://dx.doi.org/10.3389/fgene.2013.00310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567PMC
January 2014

Families Enriched for Exceptional Longevity also have Increased Health-Span: Findings from the Long Life Family Study.

Front Public Health 2013 30;1:38. Epub 2013 Sep 30.

Geriatrics Division, Department of Medicine, Boston University School of Medicine and Boston Medical Center , Boston, MA , USA.

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http://dx.doi.org/10.3389/fpubh.2013.00038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859985PMC
December 2013

Evidence of recessive Alzheimer disease loci in a Caribbean Hispanic data set: genome-wide survey of runs of homozygosity.

JAMA Neurol 2013 Oct;70(10):1261-7

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada4Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaneurol.2013.3545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991012PMC
October 2013

Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease.

Nature 2013 Aug 24;500(7460):45-50. Epub 2013 Jul 24.

Department of Pathology, Columbia University, 650 W. 168th Street, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nature12415DOI Listing
August 2013

Association of shorter leukocyte telomere repeat length with dementia and mortality.

Arch Neurol 2012 Oct;69(10):1332-9

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1001/archneurol.2012.1541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622729PMC
October 2012

Polymorphisms in HSD17B1: Early Onset and Increased Risk of Alzheimer's Disease in Women with Down Syndrome.

Curr Gerontol Geriatr Res 2012 4;2012:361218. Epub 2012 Mar 4.

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1155/2012/361218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310186PMC
August 2012

HGF/c-Met pathway is one of the mediators of sunitinib-induced tumor cell type-dependent metastasis.

Cancer Lett 2012 Jul 21;320(1):48-55. Epub 2012 Jan 21.

Oncology Research Unit, Pfizer La Jolla, CA 92121, United States.

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http://dx.doi.org/10.1016/j.canlet.2012.01.026DOI Listing
July 2012

Estrogen receptor-Beta variants are associated with increased risk of Alzheimer's disease in women with down syndrome.

Dement Geriatr Cogn Disord 2011 8;32(4):241-9. Epub 2011 Dec 8.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, G.H. Sergievsky Center, New York, N.Y., USA.

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http://dx.doi.org/10.1159/000334522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250648PMC
June 2012

Genetics and its use in Alzheimer's disease.

Psychopharmacol Bull 2007 ;40(4):132-44

Department of Neurology, Columbia University, NY, USA.

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March 2012

Impact of genetic variation in SORCS1 on memory retention.

PLoS One 2011 26;6(10):e24588. Epub 2011 Oct 26.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America.

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https://ncrad.iu.edu/docs/Publications/195_Reitz_2011.pdf
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http://dx.plos.org/10.1371/journal.pone.0024588
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024588PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202519PMC
March 2012

Association between variants in IDE-KIF11-HHEX and plasma amyloid β levels.

Neurobiol Aging 2012 Jan 17;33(1):199.e13-7. Epub 2010 Aug 17.

The Taub Institute for Research on Alzheimer's Disease and Aging Brain, Columbia University, New York, NY 10032, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580100031
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http://dx.doi.org/10.1016/j.neurobiolaging.2010.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117070PMC
January 2012

Environmental response to sewage treatment strategies: Hong Kong's experience in long term water quality monitoring.

Mar Pollut Bull 2011 Nov 25;62(11):2275-87. Epub 2011 Aug 25.

Division of Environment, Department of Civil and Environmental Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.

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http://dx.doi.org/10.1016/j.marpolbul.2011.07.020DOI Listing
November 2011

Stable isotopes as a useful tool for revealing the environmental fate and trophic effect of open-sea-cage fish farm wastes on marine benthic organisms with different feeding guilds.

Mar Pollut Bull 2011 8;63(5-12):77-85. Epub 2011 Jun 8.

The Swire Institute of Marine Science and School of Biological Sciences, Department of Civil Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.marpolbul.2011.05.005DOI Listing
October 2011

Association of common variants, not rare mutations, in IRF6 with nonsyndromic clefts in a Honduran population.

Laryngoscope 2011 Aug;121(8):1756-9

Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1002/lary.21870DOI Listing
August 2011

Novel IRF6 mutations in Honduran Van der Woude syndrome patients.

Mol Med Rep 2011 Mar-Apr;4(2):237-41. Epub 2011 Jan 11.

Columbia University College of Physicians and Surgeons, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.3892/mmr.2011.423DOI Listing
July 2011

Familial aggregation of dementia with Lewy bodies.

Arch Neurol 2011 Jan;68(1):90-3

Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1001/archneurol.2010.319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268781PMC
January 2011

Replication of the LINGO1 gene association with essential tremor in a North American population.

Eur J Hum Genet 2010 Jul 7;18(7):838-43. Epub 2010 Apr 7.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA.

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http://www.nature.com/articles/ejhg201027
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http://dx.doi.org/10.1038/ejhg.2010.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987362PMC
July 2010

Mutations in the Parkinson's disease genes, Leucine Rich Repeat Kinase 2 (LRRK2) and Glucocerebrosidase (GBA), are not associated with essential tremor.

Parkinsonism Relat Disord 2010 Feb 13;16(2):132-5. Epub 2009 Jun 13.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, NY, NY 10032, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2009.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822079PMC
February 2010

The association between interferon regulatory factor 6 (IRF6) and nonsyndromic cleft lip with or without cleft palate in a Honduran population.

Laryngoscope 2009 Sep;119(9):1759-64

Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1002/lary.20512DOI Listing
September 2009

The extended Kalman filter for forecast of algal bloom dynamics.

Water Res 2009 Sep 11;43(17):4214-24. Epub 2009 Jun 11.

Department of Civil Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong.

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http://dx.doi.org/10.1016/j.watres.2009.06.012DOI Listing
September 2009

Risk of dementia associated with elevated plasma homocysteine in a latin american population.

Int J Alzheimers Dis 2009 Aug 23;2009. Epub 2009 Aug 23.

Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.4061/2009/632489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925085PMC
August 2009

Antibiotics in the Hong Kong metropolitan area: Ubiquitous distribution and fate in Victoria Harbour.

Mar Pollut Bull 2009 Jul 5;58(7):1052-62. Epub 2009 Mar 5.

Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR, China.

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https://linkinghub.elsevier.com/retrieve/pii/S0025326X090005
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http://dx.doi.org/10.1016/j.marpolbul.2009.02.004DOI Listing
July 2009

Integrated stochastic environmental risk assessment of the harbour area treatment scheme (HATS) in Hong Kong.

Environ Sci Technol 2009 May;43(10):3705-11

Department of Civil Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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May 2009

Possible association between SORL1 and Alzheimer disease? Reanalysing the data of Shibata et al.

Dement Geriatr Cogn Disord 2008 4;26(5):482. Epub 2008 Nov 4.

Taub Institute and Sergievsky Center, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1159/000167792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703707PMC
February 2009

Comparison of clinical manifestations in Alzheimer disease and dementia with Lewy bodies.

Arch Neurol 2008 Dec;65(12):1634-9

Gertrude H. Sergievsky Center, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 W 168th St, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1001/archneur.65.12.1634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633487PMC
December 2008

Genotype-adjusted familial correlation analysis using three generalized estimating equations.

Stat Med 2008 Nov;27(26):5471-83

Pediatrics Epidemiology Center, University of South Florida, 3650 Spectrum Blvd., Suite 100, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1002/sim.3344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736642PMC
November 2008

Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci.

Arch Neurol 2008 Nov;65(11):1518-26

Gertrude H. Sergievsky Center, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.1001/archneur.65.11.1518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694670PMC
November 2008

Temporal and spatial variations in nutrient stoichiometry and regulation of phytoplankton biomass in Hong Kong waters: influence of the Pearl River outflow and sewage inputs.

Mar Pollut Bull 2008 29;57(6-12):335-48. Epub 2008 Feb 29.

Atmospheric, Marine and Coastal Environment (AMCE) Program, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.marpolbul.2008.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373556PMC
October 2008

Seasonal and spatial dynamics of nutrients and phytoplankton biomass in Victoria Harbour and its vicinity before and after sewage abatement.

Mar Pollut Bull 2008 2;57(6-12):313-24. Epub 2008 Jun 2.

Atmospheric, Marine and Coastal Environment (AMCE) Program, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, PR China.

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http://dx.doi.org/10.1016/j.marpolbul.2008.04.035DOI Listing
October 2008

The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's disease.

Curr Neurol Neurosci Rep 2008 Sep;8(5):384-91

Sergievsky Center, 630 W. 168th Street, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694663PMC
September 2008

Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models.

Drug Metab Dispos 2008 Jul 1;36(7):1267-74. Epub 2008 Apr 1.

Pharmacokinetics, Dynamics and Metabolism, La Jolla Laboratories, Pfizer Global Research and Development, 10777 Science Center Dr., San Diego, CA 92121, USA.

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.107.019711
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http://dx.doi.org/10.1124/dmd.107.019711DOI Listing
July 2008

Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome.

Dement Geriatr Cogn Disord 2008 14;25(5):476-82. Epub 2008 Apr 14.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, G.H. Sergievsky Center, New York, NY, USA.

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http://dx.doi.org/10.1159/000126495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430887PMC
June 2008

The heritability of abstract reasoning in Caribbean Latinos with familial Alzheimer disease.

Dement Geriatr Cogn Disord 2007 15;24(6):411-7. Epub 2007 Oct 15.

Taub Institute on Alzheimer's Disease and the Aging Brain, New York, NY, USA.

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http://dx.doi.org/10.1159/000109765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630497PMC
February 2008

Preclinical efficacy of the c-Met inhibitor CE-355621 in a U87 MG mouse xenograft model evaluated by 18F-FDG small-animal PET.

J Nucl Med 2008 Jan 12;49(1):129-134. Epub 2007 Dec 12.

Molecular Imaging Program at Stanford, Bio-X Program, and Department of Radiology, Stanford University, Stanford, California.

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http://dx.doi.org/10.2967/jnumed.106.038836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161137PMC
January 2008

Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.

Mol Cancer Ther 2007 Dec;6(12 Pt 1):3314-22

Department of Cancer Biology, Pfizer Global Research and Development, La Jolla Laboratories, 10724 Science Center Drive, La Jolla, CA 92121, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0365DOI Listing
December 2007

Association between SORL1 and Alzheimer's disease in a genome-wide study.

Neuroreport 2007 Nov;18(17):1761-4

Department of Medicine (Genetics Program), Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1097/WNR.0b013e3282f13e7aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631643PMC
November 2007

Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome.

Neurosci Lett 2007 Sep 25;425(2):105-9. Epub 2007 Aug 25.

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.neulet.2007.08.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131721PMC
September 2007