Joseph F Costello

Joseph F Costello

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Joseph F Costello

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Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution.

Nat Commun 2019 Aug 8;10(1):3583. Epub 2019 Aug 8.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1038/s41467-019-11526-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687891PMC
August 2019

Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts.

Toxicol Sci 2019 01;167(1):211-226

Department of Obstetrics, Gynecology, and Reproductive Sciences, Center for Reproductive Sciences, University of California, San Francisco (UCSF), San Francisco, California 94143.

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http://dx.doi.org/10.1093/toxsci/kfy230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317432PMC
January 2019

Temozolomide-associated hypermutation in gliomas.

Neuro Oncol 2018 09;20(10):1300-1309

Department of Neurological Surgery, University of California San Francisco, San Francisco, California.

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https://academic.oup.com/neuro-oncology/article/20/10/1300/4
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http://dx.doi.org/10.1093/neuonc/noy016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120358PMC
September 2018

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Nat Commun 2017 12 19;8(1):2127. Epub 2017 Dec 19.

Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, 1450 3rd Street, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1038/s41467-017-02178-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736624PMC
December 2017

Comprehensive Analysis of Hypermutation in Human Cancer.

Cell 2017 Nov 19;171(5):1042-1056.e10. Epub 2017 Oct 19.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849393PMC
November 2017

Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution.

Cold Spring Harb Perspect Med 2017 Aug 1;7(8). Epub 2017 Aug 1.

Department of Neurological Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158.

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http://dx.doi.org/10.1101/cshperspect.a026617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538404PMC
August 2017

Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters.

Oncotarget 2016 Jun;7(23):34942-55

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.18632/oncotarget.9006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085201PMC
June 2016

Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.

G3 (Bethesda) 2016 04 7;6(4):973-86. Epub 2016 Apr 7.

Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri 63108 Department of Computer Science and Engineering, Washington University in St. Louis, Missouri 63130

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http://dx.doi.org/10.1534/g3.115.025437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825665PMC
April 2016

Understanding TERT Promoter Mutations: A Common Path to Immortality.

Mol Cancer Res 2016 Apr 3;14(4):315-23. Epub 2016 Mar 3.

Department of Neurological Surgery, University of California, San Francisco, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852159PMC
April 2016

Intratumoral Heterogeneity of the Epigenome.

Cancer Cell 2016 Apr;29(4):440-451

Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.ccell.2016.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852161PMC
April 2016

Cancer: Oncogene brought into the loop.

Nature 2016 Jan 23;529(7584):34-5. Epub 2015 Dec 23.

Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nature16330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920076PMC
January 2016

The genetics of splicing in neuroblastoma.

Cancer Discov 2015 Apr 30;5(4):380-95. Epub 2015 Jan 30.

Department of Neurology, University of California, San Francisco, San Francisco, California. Department of Neurosurgery, University of California, San Francisco, San Francisco, California. Department of Pediatrics, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390477PMC
April 2015

Integrative analysis of 111 reference human epigenomes.

Nature 2015 Feb;518(7539):317-30

1] Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, Massachusetts 02139, USA. [2] The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature14248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530010PMC
February 2015

methylC Track: visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser.

Bioinformatics 2014 Aug 10;30(15):2206-7. Epub 2014 Apr 10.

Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA and Department of Neurosurgery, Brain Tumor Research Center, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103599PMC
August 2014

Recurrent epimutations activate gene body promoters in primary glioblastoma.

Genome Res 2014 May 7;24(5):761-74. Epub 2014 Apr 7.

Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, California 94143, USA;

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http://dx.doi.org/10.1101/gr.164707.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009606PMC
May 2014

ALEA: a toolbox for allele-specific epigenomics analysis.

Bioinformatics 2014 04 26;30(8):1172-1174. Epub 2013 Dec 26.

Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, V5Z 4S6, Canada, Graphics Usability and Visualization Lab, School of Computing Science, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada, Visualization and Data Analysis Lab, Faculty of Computer Science, University of Vienna, A-1090 Vienna, Austria, Department of Dermatology, University of California San Francisco, San Francisco, California 94143, USA, Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94158, USA and Department of Medical Genetics, Life Sciences Institute, The University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btt744DOI Listing
April 2014

Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.

Neuro Oncol 2014 Mar 4;16(3):361-71. Epub 2013 Dec 4.

Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, San Francisco, California (S.D.F., C.D.J., S.C., J.F.C); Department of Radiation Oncology, University of California, San Francisco, California (J.L.N.).

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http://dx.doi.org/10.1093/neuonc/not223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922516PMC
March 2014

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.

Nat Rev Cancer 2014 Feb;14(2):92-107

1] Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany. [2] Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/nrc3655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003223PMC
February 2014

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.

Nat Biotechnol 2013 Dec 9;31(12):1137-42. Epub 2013 Oct 9.

1] Department of Pathology and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts, USA. [4].

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http://www.nature.com/articles/nbt.2726
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http://dx.doi.org/10.1038/nbt.2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858462PMC
December 2013

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods.

Genome Res 2013 Sep 26;23(9):1541-53. Epub 2013 Jun 26.

Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1101/gr.152231.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759729PMC
September 2013

Cancer Stem Cells Activate STAT3 the EZ Way.

Cancer Cell 2013 Jun;23(6):711-3

Brain Tumor Research Center, Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.ccr.2013.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706087PMC
June 2013

Methods for cancer epigenome analysis.

Adv Exp Med Biol 2013 ;754:313-38

University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-4419-9967-2_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090090PMC
December 2012

A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.

Cancer Res 2012 Dec 27;72(24):6319-24. Epub 2012 Nov 27.

Research Department of Cancer Biology, University College London Cancer Institute, University College London, London, United Kingdom.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-3658DOI Listing
December 2012

Spark: a navigational paradigm for genomic data exploration.

Genome Res 2012 Nov 7;22(11):2262-9. Epub 2012 Sep 7.

Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, V5Z 4S6, Canada.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.140665.112
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http://dx.doi.org/10.1101/gr.140665.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483555PMC
November 2012

Epigenetic silencing of MIR203 in multiple myeloma.

Br J Haematol 2011 Sep 28;154(5):569-78. Epub 2011 Jun 28.

Departments of Medicine Pathology Biochemistry, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08782.xDOI Listing
September 2011

Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.

Nat Cell Biol 2011 May 17;13(5):541-9. Epub 2011 Apr 17.

Department of Ob/Gyn and Center for Reproductive Sciences, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA.

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http://www.nature.com/articles/ncb2239
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http://dx.doi.org/10.1038/ncb2239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987913PMC
May 2011

The transversus abdominis plane block, when used as part of a multimodal regimen inclusive of intrathecal morphine, does not improve analgesia after cesarean delivery.

Reg Anesth Pain Med 2009 Nov-Dec;34(6):586-9

Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://pdfs.journals.lww.com/rapm/2009/11000/The_Transversus
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February 2010

Genome-scale DNA methylation analysis.

Epigenomics 2010 Feb;2(1):105-17

Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, CA 94158, USA.

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http://dx.doi.org/10.2217/epi.09.35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907108PMC
February 2010

Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.

Cancer Res 2010 Jan 12;70(2):453-62. Epub 2010 Jan 12.

The Brain Tumor Research Center, Department of Neurological Surgery, University of California-San Francisco, San Francisco, California 94158-9001, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849935PMC
January 2010

Epigenetics of neurological cancers.

Future Oncol 2009 Dec;5(10):1615-29

Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.2217/fon.09.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018230PMC
December 2009

A first look at entire human methylomes.

Nat Biotechnol 2009 Dec;27(12):1130-2

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http://dx.doi.org/10.1038/nbt1209-1130DOI Listing
December 2009

Epigenetic silencing of the kinase tumor suppressor WNK2 is tumor-type and tumor-grade specific.

Neuro Oncol 2009 Aug 11;11(4):414-22. Epub 2008 Nov 11.

Department of Neurological Surgery, University of California, San Francisco, Cancer Center, Room N225, 2340 Sutter St., San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1215/15228517-2008-096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743221PMC
August 2009

Molecular epigenetics and genetics in neuro-oncology.

Neurotherapeutics 2009 Jul;6(3):436-46

Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1016/j.nurt.2009.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981537PMC
July 2009

Epigenetic mechanisms in glioblastoma multiforme.

Semin Cancer Biol 2009 Jun 20;19(3):188-97. Epub 2009 Feb 20.

Brain Tumor Research Center, Department of Neurosurgery, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.semcancer.2009.02.005DOI Listing
June 2009

Restriction landmark genomic scanning: analysis of CpG islands in genomes by 2D gel electrophoresis.

Methods Mol Biol 2009 ;507:131-48

Department of Neurological Surgery, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-59745-522-0_11DOI Listing
March 2009

Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism.

Crit Care Med 2008 Dec;36(12):3135-44

Department of Anesthesia, Clinical Sciences Institute, National University of Ireland, Galway, Ireland.

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https://insights.ovid.com/crossref?an=00003246-200812000-000
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http://dx.doi.org/10.1097/CCM.0b013e31818f0d13DOI Listing
December 2008

Cesarean delivery under ultrasound-guided spinal anesthesia [corrected] in a parturient with poliomyelitis and Harrington instrumentation.

Can J Anaesth 2008 Sep;55(9):606-11

Department of Anesthesia and Pain Management, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G1X5, Canada.

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September 2008

Stem cells: Tips for priming potency.

Nature 2008 Jul;454(7200):45-6

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http://www.nature.com/doifinder/10.1038/454045a
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http://dx.doi.org/10.1038/454045aDOI Listing
July 2008

Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury.

BMC Pulm Med 2008 Jul 8;8. Epub 2008 Jul 8.

Lung Biology Group, National Centre for Biomedical Engineering Sciences, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1186/1471-2466-8-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467400PMC
July 2008

Molecular signatures define two main classes of meningiomas.

Mol Cancer 2007 Oct 15;6:64. Epub 2007 Oct 15.

Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, CA-94143, USA.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-6-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173907PMC
October 2007

Epigenome scans and cancer genome sequencing converge on WNK2, a kinase-independent suppressor of cell growth.

Proc Natl Acad Sci U S A 2007 Jun 19;104(26):10974-9. Epub 2007 Jun 19.

*Department of Neurological Surgery and the Comprehensive Cancer Center, University of California, San Francisco, CA 94143.

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http://dx.doi.org/10.1073/pnas.0700683104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904113PMC
June 2007

Lack of germ-line promoter methylation in BRCA1-negative families with familial breast cancer.

Genet Test 2006 ;10(4):281-4

Department of Neurological Surgery, UCSF Comprehensive Cancer Center, San Francisco, California 9443-0875, USA.

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http://www.liebertpub.com/doi/10.1089/gte.2006.10.281
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http://dx.doi.org/10.1089/gte.2006.10.281DOI Listing
April 2007

Genome-epigenome interactions in cancer.

Hum Mol Genet 2007 Apr;16 Spec No 1:R96-105

Department of Molecular Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1093/hmg/ddm073DOI Listing
April 2007

Mining methylation for early detection of common cancers.

PLoS Med 2006 Dec;3(12):e479

Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.0030479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762083PMC
December 2006

Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation.

Cancer Res 2006 Sep;66(17):8469-76

The Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, CA 94143-0875, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-06-1547DOI Listing
September 2006

Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells.

J Biol Chem 2006 Aug 9;281(34):24790-802. Epub 2006 Jun 9.

Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California 94143-0511, USA.

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http://dx.doi.org/10.1074/jbc.M604175200DOI Listing
August 2006

DNA motifs associated with aberrant CpG island methylation.

Genomics 2006 May 17;87(5):572-9. Epub 2006 Feb 17.

Department of Radiation Oncology and Winship Cancer Institute, Emory University School of Medicine, 1365-C Clifton Road. NE, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.ygeno.2005.12.016DOI Listing
May 2006

A broad band of silence.

Nat Genet 2006 May;38(5):504-6

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http://dx.doi.org/10.1038/ng0506-504DOI Listing
May 2006

Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3.

Nat Genet 2005 Jun 15;37(6):645-51. Epub 2005 May 15.

The Brain Tumor Research Center, Department of Neurological Surgery and the Biomedical Sciences Program, University of California San Francisco, San Franciso, California 94143, USA.

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http://dx.doi.org/10.1038/ng1563DOI Listing
June 2005

Meningioma transcript profiles reveal deregulated Notch signaling pathway.

Cancer Res 2005 Jun;65(12):5070-5

Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-0240DOI Listing
June 2005

Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8.

Cancer Res 2005 May;65(9):3617-23

Department of Neurological Surgery, Brain Tumor Research Center, University of California-San Francisco, San Francisco, California 94143-0875, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0048DOI Listing
May 2005

Comparative epigenomics of leukemia.

Nat Genet 2005 Mar;37(3):211-2

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http://www.nature.com/articles/ng0305-211
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http://dx.doi.org/10.1038/ng0305-211DOI Listing
March 2005

Phosphatase and tensin homologue growth suppression without phosphatase.

Proc Natl Acad Sci U S A 2005 Feb 14;102(8):2677-8. Epub 2005 Feb 14.

Cancer Research Institute and Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.0500089102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549471PMC
February 2005

SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer.

Proc Natl Acad Sci U S A 2003 Nov 14;100(24):14133-8. Epub 2003 Nov 14.

Thoracic Oncology Laboratory, Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA.

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http://dx.doi.org/10.1073/pnas.2232790100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC283558PMC
November 2003

The contribution of genetic and epigenetic mechanisms to gene silencing in oligodendrogliomas.

Cancer Res 2003 Nov;63(22):7600-5

Department of Neurological Surgery, The Brain Tumor Research Center, Department of Pathology, Comprehensive Cancer Center, University of California-San Francisco, 2340 Sutter Street, San Francisco, CA 94143, USA.

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November 2003

DNA methylation in brain development and gliomagenesis.

Front Biosci 2003 Jan 1;8:s175-84. Epub 2003 Jan 1.

The Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, 2340 Sutter, San Francisco, CA 94115, USA.

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http://dx.doi.org/10.2741/1027DOI Listing
January 2003

Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors.

Nat Genet 2002 Nov 30;32(3):453-8. Epub 2002 Sep 30.

Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California 94115, USA.

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http://dx.doi.org/10.1038/ng1007DOI Listing
November 2002

Restriction landmark genome scanning.

Methods Mol Biol 2002 ;200:53-70

Department of Neurological Surgery, UCSF Brain Tumor Research Center, San Francisco, CA, USA.

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http://dx.doi.org/10.1385/1-59259-182-5:053DOI Listing
October 2002

Methylation matters: a new spin on maspin.

Nat Genet 2002 Jun;31(2):123-4

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http://dx.doi.org/10.1038/ng0602-123DOI Listing
June 2002

Restriction landmark genome scanning.

Methods 2002 Jun;27(2):144-9

University of California-San Francisco, San Francisco, CA 94115-0875, USA.

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June 2002