Publications by authors named "Joseph C Wu"

100Publications

Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells.

Circulation 2020 Sep 15. Epub 2020 Sep 15.

Stanford Cardiovascular Institute, Department of Medicine, Division of Cardiology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.041433DOI Listing
September 2020

Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome.

Cell Stem Cell 2020 Aug 10. Epub 2020 Aug 10.

Department of Pediatrics, Division of Pediatric Cardiology, Stanford School of Medicine, Stanford, CA 94305, USA; Vera Moulton Wall Center for Pulmonary Vascular Disease, Stanford School of Medicine, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford School of Medicine, Stanford, CA 94305, USA; Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Center for Stem Cell and Organoid Medicine, CuSTOM, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2020.07.015DOI Listing
August 2020

A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants.

PLoS Comput Biol 2020 08 14;16(8):e1008109. Epub 2020 Aug 14.

Department of Physiology and Membrane Biology, Department of Pharmacology, School of Medicine, University of California, Davis, Davis, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1008109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449496PMC
August 2020

An extracellular matrix paradox in myocardial scar formation.

Signal Transduct Target Ther 2020 Aug 12;5(1):151. Epub 2020 Aug 12.

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41392-020-00270-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423912PMC
August 2020

Induced pluripotent stem cells as a platform to understand patient-specific responses to opioids and anaesthetics.

Br J Pharmacol 2020 Aug 7. Epub 2020 Aug 7.

Stanford Cardiovascular Institute, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1111/bph.15228DOI Listing
August 2020

Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates.

Dev Cell 2020 Jul 28. Epub 2020 Jul 28.

Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA; Departments of Medicine and Radiology, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.07.006DOI Listing
July 2020

Tumor Repressor Circular RNA as a New Target for Preventative Gene Therapy Against Doxorubicin-Induced Cardiotoxicity.

Circ Res 2020 Jul 30;127(4):483-485. Epub 2020 Jul 30.

From the Stanford Cardiovascular Institute (J.W.S.J., L.L., J.C.W.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.120.317568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462737PMC
July 2020

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.

Nat Rev Cardiol 2020 09 20;17(9):543-558. Epub 2020 Jul 20.

Stanford Cardiovascular Institute, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41569-020-0413-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7370876PMC
September 2020

The impact of sleep deprivation on sexual behaviors and FAAH expression in the prefrontal cortex of male rats.

Neurosci Lett 2020 Sep 16;735:135254. Epub 2020 Jul 16.

Research Center of Psychiatry and Behavioral Sciences, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2020.135254DOI Listing
September 2020

Generation of Quiescent Cardiac Fibroblasts Derived from Human Induced Pluripotent Stem Cells.

Methods Mol Biol 2020 Jul 16. Epub 2020 Jul 16.

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/7651_2020_300DOI Listing
July 2020

Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Cell Rep 2020 Jul;32(2):107886

Stanford Cardiovascular Institute, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiovascular Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA; Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305 USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107886DOI Listing
July 2020

Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes.

Cell Stem Cell 2020 Jul;27(1):50-63.e5

Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2020.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334437PMC
July 2020

High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human iPSCs for Multi-omics Analysis.

Curr Protoc Stem Cell Biol 2020 09;54(1):e114

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1002/cpsc.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442745PMC
September 2020

Molecular Imaging of Infective Endocarditis With 6''-[F]Fluoromaltotriose Positron Emission Tomography-Computed Tomography.

Circulation 2020 May 26;141(21):1729-1731. Epub 2020 May 26.

Department of Radiology, Molecular Imaging Program at Stanford (MIPS), Bio-X Program (M.W., G.G., E.C., M.N., T.H., M.T.G., J.C.W., S.S.G.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.043924DOI Listing
May 2020

Human induced pluripotent stem cells for modelling metabolic perturbations and impaired bioenergetics underlying cardiomyopathies.

Cardiovasc Res 2020 May 4. Epub 2020 May 4.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.

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http://dx.doi.org/10.1093/cvr/cvaa125DOI Listing
May 2020

Levitating Cells to Sort the Fit and the Fat.

Adv Biosyst 2020 Jun 30;4(6):e1900300. Epub 2020 Apr 30.

Canary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Stanford University, Palo Alto, CA, 94304, USA.

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http://dx.doi.org/10.1002/adbi.201900300DOI Listing
June 2020

Cardiovascular Risks in Patients with COVID-19: Potential Mechanisms and Areas of Uncertainty.

Curr Cardiol Rep 2020 04 29;22(5):34. Epub 2020 Apr 29.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University, 1265 Welch Road, Rm 3250, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/s11886-020-01293-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189178PMC
April 2020

Simple Lithography-Free Single Cell Micropatterning using Laser-Cut Stencils.

J Vis Exp 2020 04 3(158). Epub 2020 Apr 3.

Stanford Cardiovascular Institute, Stanford University School of Medicine; Department of Medicine, Division of Cardiovascular Medicine, Stanford University; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University; Department of Medicine III, University Hospital Heidelberg; German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim;

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http://dx.doi.org/10.3791/60888DOI Listing
April 2020

Molecular Signatures of Beneficial Class Effects of Statins on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Circulation 2020 Apr 6;141(14):1208-1210. Epub 2020 Apr 6.

Stanford Cardiovascular Institute (L.T., A.O., C.L., T.K., C.L.C., S.-G.O., M.S., I.K., N.S., J.C.W.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170011PMC
April 2020

Single-cell RNA sequencing in cardiovascular development, disease and medicine.

Nat Rev Cardiol 2020 Aug 30;17(8):457-473. Epub 2020 Mar 30.

Stanford Cardiovascular Institute, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41569-020-0359-yDOI Listing
August 2020

Gut microbiota and cardiovascular disease: opportunities and challenges.

Microbiome 2020 03 14;8(1):36. Epub 2020 Mar 14.

School of Engineering, University of British Columbia, Kelowna, Kelowna, BC, Canada.

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http://dx.doi.org/10.1186/s40168-020-00821-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071638PMC
March 2020

Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy.

J Am Coll Cardiol 2020 Mar;75(10):1159-1174

Lillehei Heart Institute, Cardiovascular Division, University of Minnesota, Minneapolis, Minnesota; Paul and Sheila Muscular Dystrophy Center, University of Minnesota, Minneapolis, Minnesota; Department of Integrative Biology and Physiology, University of Minnesota, Minneapolis, Minnesota; Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.12.066DOI Listing
March 2020

Using Bioengineered Bioluminescence to Track Stem Cell Transplantation In Vivo.

Methods Mol Biol 2020 ;2126:1-11

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/978-1-0716-0364-2_1DOI Listing
January 2020

Therapeutic genome editing in cardiovascular diseases.

Adv Drug Deliv Rev 2020 Feb 21. Epub 2020 Feb 21.

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, United States; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States; Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2020.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442585PMC
February 2020

RNA Sequencing Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes From Congenital Heart Disease Patients.

Circ Res 2020 Mar 19;126(7):923-925. Epub 2020 Feb 19.

From the Stanford Cardiovascular Institute (T.K., L.T., T.Z., I.I., J.Z.Z., N.M., C.L., J.-W.R., J.C.W.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123776PMC
March 2020

Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes From Children With DCMA, a Mitochondrial Cardiomyopathy.

Can J Cardiol 2020 Apr 9;36(4):554-563. Epub 2019 Oct 9.

Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada; Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2019.09.021DOI Listing
April 2020

Total Microfluidic chip for Multiplexed diagnostics (ToMMx).

Biosens Bioelectron 2020 Feb 28;150:111930. Epub 2019 Nov 28.

Bio-Acoustic MEMS in Medicine (BAMM) Laboratory, Canary Center at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine Stanford University Palo Alto, CA, 94304, USA; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2019.111930DOI Listing
February 2020

Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics.

Pharmacol Rev 2020 01;72(1):320-342

Stanford Cardiovascular Institute, Stanford University, Stanford, California

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http://dx.doi.org/10.1124/pr.116.013003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934989PMC
January 2020

Electronic Cigarettes: Where There Is Smoke There Is Disease.

J Am Coll Cardiol 2019 12;74(25):3121-3123

Stanford Cardiovascular Institute and Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1016/j.jacc.2019.10.029DOI Listing
December 2019

NanoMEA: A Tool for High-Throughput, Electrophysiological Phenotyping of Patterned Excitable Cells.

Nano Lett 2020 03 23;20(3):1561-1570. Epub 2019 Dec 23.

Department of Bioengineering, University of Washington, Seattle, Washington 98195, United States.

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http://dx.doi.org/10.1021/acs.nanolett.9b04152DOI Listing
March 2020

Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome.

Cell Rep 2019 12;29(11):3751-3765.e5

Consortium for Fibrosis Research and Translation, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA; Departments of Medicine-Cardiology and Biochemistry and Molecular Genetics, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6961840PMC
December 2019

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function.

Stem Cell Reports 2019 12 7;13(6):960-969. Epub 2019 Nov 7.

Stanford Cardiovascular Institute, Stanford University School of Medicine, 265 Campus Drive, Room G1120B, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915842PMC
December 2019

Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms.

Circ Res 2019 10 10;125(9):855-867. Epub 2019 Oct 10.

Division of Cardiovascular and Renal Products, Center for Drug Evaluation and Research, U.S. Food and Drug Administration (N.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788760PMC
October 2019

Improving the engraftment and integration of cell transplantation for cardiac regeneration.

Cardiovasc Res 2020 Mar;116(3):473-475

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1093/cvr/cvz237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252439PMC
March 2020

Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies.

Circ Res 2019 08 29;125(6):653-658. Epub 2019 Aug 29.

Istituto Auxologico Italiano, IRCCS, Center for Cardiac Arrhythmias of Genetic Origin, and Laboratory of Cardiovascular Genetics, Milan, Italy (P.J.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315209DOI Listing
August 2019

Induced pluripotent stem cells as a novel cancer vaccine.

Expert Opin Biol Ther 2019 11 12;19(11):1191-1197. Epub 2019 Aug 12.

Cardiovascular Institute, Stanford University School of Medicine , Stanford , CA , USA.

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http://dx.doi.org/10.1080/14712598.2019.1650909DOI Listing
November 2019

Induced Pluripotent Stem Cell-Based Cancer Vaccines.

Front Immunol 2019 8;10:1510. Epub 2019 Jul 8.

Cardiovascular Institute, School of Medicine, Stanford University, Stanford, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.01510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628907PMC
July 2019

Clinical Trial in a Dish: Personalized Stem Cell-Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT-Prolonging Drugs.

Clin Transl Sci 2019 11 29;12(6):687-697. Epub 2019 Aug 29.

Center for Drug Evaluation and Research, Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, Maryland, USA.

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http://dx.doi.org/10.1111/cts.12674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853144PMC
November 2019

Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis.

Circ Res 2019 08 10;125(5):552-566. Epub 2019 Jul 10.

From the Stanford Cardiovascular Institute (H.Z., L.T., M.S., C.T., H.W., D.T.P., J.C.W.), CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768436PMC
August 2019

Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution.

Circ Res 2019 08 9;125(4):379-397. Epub 2019 Jul 9.

From the Cardiovascular Institute (W.R.G., B.M.B., D.T.P., L.T., G.L., J.W.B., O.C., S.C., S.V., J.C.W., S.M.W.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675655PMC
August 2019

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources.

J Physiol 2019 09 27;597(17):4533-4564. Epub 2019 Jul 27.

Department of Physiology and Membrane Biology, Department of Pharmacology, School of Medicine, University of California, Davis, Davis, CA, USA.

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http://dx.doi.org/10.1113/JP277724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767694PMC
September 2019

Generation of Endothelial Cells From Human Pluripotent Stem Cells.

Arterioscler Thromb Vasc Biol 2019 07 9;39(7):1317-1329. Epub 2019 May 9.

From the Stanford Cardiovascular Institute, Division of Cardiovascular Medicine, Department of Medicine, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, CA.

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http://dx.doi.org/10.1161/ATVBAHA.119.312265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597190PMC
July 2019

Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.

Eur Heart J 2019 12;40(45):3685-3695

Stanford Cardiovascular Institute, Stanford University School of Medicine, 265 Campus Drive, Stanford, CA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehz326DOI Listing
December 2019

A Combination of Itraconazole and Amiodarone Is Highly Effective against Infection of Human Stem Cell-Derived Cardiomyocytes.

Am J Trop Med Hyg 2019 08;101(2):383-391

Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.4269/ajtmh.19-0023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685576PMC
August 2019

Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells.

J Am Coll Cardiol 2019 06;73(21):2722-2737

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California; Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.03.476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637948PMC
June 2019

Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development.

Development 2019 06 14;146(12). Epub 2019 Jun 14.

Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA

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http://dx.doi.org/10.1242/dev.173476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602356PMC
June 2019

Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection.

Stem Cell Reports 2019 06 16;12(6):1232-1241. Epub 2019 May 16.

Stanford Cardiovascular Institute, 265 Campus Drive, Rm G1120B, Stanford, CA 94305, USA; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, School of Medicine, Stanford, CA 94305, USA; Department of Radiology, Stanford University, School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565757PMC
June 2019

Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Circ Res 2019 07 13;125(2):212-222. Epub 2019 May 13.

From the Stanford Cardiovascular Institute, CA (C.K.L., L.T., N.B., A.W., R.S., N.M., T.K., J.-W.R., J.C.W.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610656PMC
July 2019

Stanford Cardiovascular Institute.

Circ Res 2019 05;124(10):1420-1424

From the Stanford Cardiovascular Institute (J.C.W., Y.J.W., M.M., R.A.H., T.Q.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.310761DOI Listing
May 2019

Harnessing cell pluripotency for cardiovascular regenerative medicine.

Nat Biomed Eng 2018 06 11;2(6):392-398. Epub 2018 Jun 11.

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1038/s41551-018-0244-8DOI Listing
June 2018

Complex heritability in cardiomyopathy.

Nat Biomed Eng 2019 02;3(2):87-89

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://www.nature.com/articles/s41551-019-0353-z
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http://dx.doi.org/10.1038/s41551-019-0353-zDOI Listing
February 2019

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.

Cell Stem Cell 2019 05 14;24(5):802-811.e5. Epub 2019 Mar 14.

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909193006
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http://dx.doi.org/10.1016/j.stem.2019.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499654PMC
May 2019

Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development.

Stem Cell Reports 2019 04 28;12(4):772-786. Epub 2019 Feb 28.

Stanford Cardiovascular Institute, 265 Campus Drive G1120B, Stanford, CA 94305, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA; Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449785PMC
April 2019

Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell.

Cardiovasc Res 2019 04;115(5):949-959

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1093/cvr/cvz024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933506PMC
April 2019

Myocardial viability of the peri-infarct region measured by T1 mapping post manganese-enhanced MRI correlates with LV dysfunction.

Int J Cardiol 2019 Apr 31;281:8-14. Epub 2019 Jan 31.

Department of Medicine (Cardiovascular Medicine) and Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2019.01.101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434939PMC
April 2019

Systems-Wide Approaches in Induced Pluripotent Stem Cell Models.

Annu Rev Pathol 2019 01 31;14:395-419. Epub 2018 Oct 31.

Stanford Cardiovascular Institute, and Department of Medicine, Division of Cardiology, Stanford University, Stanford, California 94305, USA; email:

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https://www.annualreviews.org/doi/10.1146/annurev-pathmechdi
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http://dx.doi.org/10.1146/annurev-pathmechdis-012418-013046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450651PMC
January 2019

Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Circ Res 2018 08;123(5):512-514

From the Stanford Cardiovascular Institute (C.T., B.S.C., J.C.W.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392006PMC
August 2018

From the BCVS Chair.

Authors:
Joseph C Wu

Circ Res 2018 09;123(8):942-943

From the Stanford Cardiovascular Institute, Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314019DOI Listing
September 2018

Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity.

J Proteome Res 2018 12 9;17(12):4267-4278. Epub 2018 Oct 9.

Department of Medicine, Division of Cardiology, Consortium for Fibrosis Research and Translation, Anschutz Medical Campus , University of Colorado Denver , Aurora , Colorado 80045 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.8b00393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606054PMC
December 2018

Cytokines profile of reverse cardiac remodeling following transcatheter aortic valve replacement.

Int J Cardiol 2018 Nov;270:83-88

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States; Stanford Cardiovascular Institute, Stanford, CA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273173805
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http://dx.doi.org/10.1016/j.ijcard.2018.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140353PMC
November 2018

Telomere shortening is a hallmark of genetic cardiomyopathies.

Proc Natl Acad Sci U S A 2018 09 27;115(37):9276-9281. Epub 2018 Aug 27.

Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1714538115
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http://dx.doi.org/10.1073/pnas.1714538115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140486PMC
September 2018

Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come?

Eur Heart J 2018 11;39(43):3893-3895

Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehy388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234848PMC
November 2018

Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant.

J Am Coll Cardiol 2018 07;72(1):62-75

Stanford Cardiovascular Institute and Department of Medicine, Division of Cardiology, Stanford University, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.04.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050025PMC
July 2018

Progress, obstacles, and limitations in the use of stem cells in organ-on-a-chip models.

Adv Drug Deliv Rev 2019 02 6;140:3-11. Epub 2018 Jun 6.

Stanford Cardiovascular Institute, Stanford, CA 94305, United States; Division of Cardiovascular Medicine, Department of Medicine, Stanford, CA 94305, United States; Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281815PMC
February 2019

Effects of Repetitive Transendocardial CD34 Cell Transplantation in Patients With Nonischemic Dilated Cardiomyopathy.

Circ Res 2018 07 7;123(3):389-396. Epub 2018 Jun 7.

Stanford Cardiovascular Institute, Stanford University School of Medicine, CA (F.H., J.C.W.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312170DOI Listing
July 2018

Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm.

Arterioscler Thromb Vasc Biol 2018 08;38(8):1796-1805

From the Division of Cardiovascular Medicine, Cardiovascular Institute, Stanford University School of Medicine, CA (M.A., N.G.K., A.J., M.U.W., Y.W., YK., K.T., U.R., I.N.S., L.M., J.M.S., J.C.W., P.S.T.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652227PMC
August 2018