Publications by authors named "Joseph A Ludwig"

43Publications

Primary Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Kidney: The MD Anderson Cancer Center Experience.

Cancers (Basel) 2020 Oct 11;12(10). Epub 2020 Oct 11.

Department of Pediatrics, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers12102927DOI Listing
October 2020

Modeling the Tumor Microenvironment and Pathogenic Signaling in Bone Sarcoma.

Tissue Eng Part B Rev 2020 06 14;26(3):249-271. Epub 2020 Feb 14.

Department of Bioengineering, Rice University, Houston, Texas.

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http://dx.doi.org/10.1089/ten.teb.2019.0302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310212PMC
June 2020

Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor.

Neoplasia 2018 05 5;20(5):524-532. Epub 2018 Apr 5.

Department of Veterinary Medicine & Surgery, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit, 0063, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.neo.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915995PMC
May 2018

IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma.

J Natl Cancer Inst 2016 12 30;108(12). Epub 2016 Aug 30.

Departments of Sarcoma Medical Oncology (SELC, BAM, VR, RSB, RR, JAL), Hematopathology (DV, HMA), Bioinformatics and Computational Biology (YW, JW), Investigational Cancer Therapeutics (AN, VS), Pediatrics-Patient Care (NCD), Experimental Therapeutics (IF, SS, WP), and Pathology (AJL), The University of Texas MD Anderson Cancer Center, Houston, TX; Departments of Radiology (EMR) and Molecular & Human Genetics (RLM), Baylor College of Medicine, Houston, TX; Department of Pediatric-Oncology, Texas Children's Hospital. Houston, TX (ASB); Departments of Chemical and Biomolecular Engineering and Bioengineering, Rice University, Houston, TX (AGM)

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http://dx.doi.org/10.1093/jnci/djw182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241894PMC
December 2016

Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma.

Proc Natl Acad Sci U S A 2015 Aug 3;112(33):10304-9. Epub 2015 Aug 3.

Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005; Department of Bioengineering, Rice University, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.1506684112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547215PMC
August 2015

Prognostic factors and patterns of relapse in ewing sarcoma patients treated with chemotherapy and r0 resection.

Int J Radiat Oncol Biol Phys 2015 Jun 12;92(2):349-57. Epub 2015 Mar 12.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431926PMC
June 2015

Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors.

PLoS One 2014 13;9(8):e93676. Epub 2014 Aug 13.

Department of Investigational Cancer Therapeutics (Phase I Clinical Trials Program), Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America; Center for Personalized Cancer Therapy and Division of Hematology & Oncology, University of California San Diego - Moores Cancer Center, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093676PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131855PMC
December 2015

3D tissue-engineered model of Ewing's sarcoma.

Adv Drug Deliv Rev 2014 Dec 7;79-80:155-71. Epub 2014 Aug 7.

Department of Sarcoma Medical Oncology, University of Texas MD Anderson Cancer Center (MDACC), Houston, TX 77054, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2014.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397982PMC
December 2014

Universal marker and detection tool for human sarcoma circulating tumor cells.

Cancer Res 2014 Mar 21;74(6):1645-50. Epub 2014 Jan 21.

Authors' Affiliations: Departments of Pediatrics and Surgical Oncology; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center; and UTMD Graduate School of Biomedical Sciences, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959622PMC
March 2014

Dual targeting of the insulin-like growth factor and collateral pathways in cancer: combating drug resistance.

Cancers (Basel) 2011 Jul 26;3(3):3029-54. Epub 2011 Jul 26.

Departments of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.3390/cancers3033029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759185PMC
July 2011

Review: Ewing sarcoma treatment: a role for bisphosphonates?

Clin Adv Hematol Oncol 2010 Jul;8(7):503-4

Department of Pediatrics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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July 2010

Neoadjuvant treatment of soft-tissue sarcoma: a multimodality approach.

J Surg Oncol 2010 Mar;101(4):327-33

Department of Sarcoma Medical Oncology, M.D. Anderson Cancer Center, The University of Texas, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/jso.21481DOI Listing
March 2010

Engineering tumors: a tissue engineering perspective in cancer biology.

Tissue Eng Part B Rev 2010 Jun;16(3):351-9

Department of Bioengineering, Rice University, Houston, Texas, USA.

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http://dx.doi.org/10.1089/ten.TEB.2009.0676DOI Listing
June 2010

Ewing's sarcoma: standard and experimental treatment options.

Curr Treat Options Oncol 2009 Apr 17;10(1-2):126-40. Epub 2009 Jun 17.

Department of Sarcoma Medical Oncology, Division of Cancer Medicine, Labortory of Sarcoma Molecular Therapeutics, M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s11864-009-0104-6DOI Listing
April 2009

Personalized therapy of sarcomas: integration of biomarkers for improved diagnosis, prognosis, and therapy selection.

Authors:
Joseph A Ludwig

Curr Oncol Rep 2008 Jul;10(4):329-37

Laboratory of Sarcoma Molecular Therapeutics, Department of Sarcoma Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Unit 450, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s11912-008-0051-6DOI Listing
July 2008

Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future.

Authors:
Joseph A Ludwig

Curr Opin Oncol 2008 Jul;20(4):412-8

Department of Sarcoma Medical Oncology, M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1097/CCO.0b013e328303ba1dDOI Listing
July 2008

A stromal gene signature associated with inflammatory breast cancer.

Int J Cancer 2008 Mar;122(6):1324-32

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4258, USA.

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http://doi.wiley.com/10.1002/ijc.23237
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http://dx.doi.org/10.1002/ijc.23237DOI Listing
March 2008

Comparison of drug transporter levels in normal colon, colon cancer, and Caco-2 cells: impact on drug disposition and discovery.

Mol Pharm 2006 Jan-Feb;3(1):87-93

Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1021/mp050090kDOI Listing
June 2006

Targeting multidrug resistance in cancer.

Nat Rev Drug Discov 2006 Mar;5(3):219-34

Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, Budapest Karolina út 29; H-1518 Hungary.

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http://dx.doi.org/10.1038/nrd1984DOI Listing
March 2006

Biomarkers in cancer staging, prognosis and treatment selection.

Nat Rev Cancer 2005 Nov;5(11):845-56

Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nrc1739DOI Listing
November 2005