Publications by authors named "Josefine Theresia Maier"

4 Publications

  • Page 1 of 1

Peripartum Covid-19 Pneumonia with Severe ARDS - A Case Report.

Z Geburtshilfe Neonatol 2021 04 19;225(2):183-187. Epub 2021 Apr 19.

Department of Gynecology and Obstetrics, Vivantes Klinikum im Friedrichshain, Berlin, Germany.

Introduction: SARS-CoV-2 is a novel coronavirus that was first isolated in Wuhan, China, and resulted in a rapidly spreading pandemic worldwide. Currently there is only limited evidence on the effect of COVID-19 on pregnant women.

Case: Here we present one of the first serious COVID-19 cases in pregnancy at term with subsequent delivery. Postpartum the mother required antibiotic and symptomatic treatment. She experienced acute worsening of symptoms and developed acute respiratory failure requiring endotracheal intubation and subsequently extracorporeal membrane oxygenation.

Conclusion: COVID-19 affects all medical disciplines, requiring interdisciplinary approaches and development of patient care regimes. Obstetricians should be aware and be prepared for the special needs of pregnant women with potential prenatal and postnatal issues. Ideally pregnant COVID-19 patients should be cared for at a tertiary perinatal center with experienced perinatologists and neonatologists.
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April 2021

Severe Lactational Mastitis With Complicated Wound Infection Caused by .

J Hum Lact 2021 Feb 17;37(1):200-206. Epub 2020 Nov 17.

27695 Department of Gynecology and Obstetrics, Baby-friendly Hospital Initiative certified, Tertiary Perinatal Center, Charité University hospital affiliate, Vivantes Klinikum im Friedrichshain, Berlin, Germany.

Introduction: Puerperal mastitis, a complication occurring during the breastfeeding period, is often caused by . Here we report on severe mastitis in a lactating breast, with subsequent invasive disease and wound healing problems.

Main Issue: The 41-year-old woman (G2, P2) presented at 2 weeks postpartum to our hospital with painful swelling and reddening of the left breast, in addition to fever and malaise, and complained about a nipple fissure on the left breast. Previously, her 4-year-old son was treated for an acute otitis media and her husband experienced flu-like symptoms.

Management: Due to the severity of the symptoms, Clindamycin antibiotic treatment was initiated intravenously. was isolated in the milk. This strain is commonly known to cause infections of the upper respiratory tract, skin, and soft tissue, but rarely mastitis. Furthermore, the participant developed invasive disease with abscess formation and skin erosion with a milk fistula. Special dressing was applied to promote wound healing. The participant continued breastfeeding well into the child's 2nd year of life.

Conclusion: This rare form of complicated mastitis with invasive disease caused by called for an interdisciplinary approach. We want to draw attention to other pathogens causing mastitis and to alert health care workers to promote hygiene in lactating women to prevent transmission.
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February 2021

Antenatal body mass index (BMI) and weight gain in pregnancy - its association with pregnancy and birthing complications.

J Perinat Med 2016 May;44(4):397-404

Background: Overweight and obesity is a serious health risk in both developed and developing nations. It is a common finding among women in their reproductive age. Half of patients entering their pregnancy in the US have a BMI >25.0 and therefore qualify as overweight or obese. Moreover, there is a tendency towards increased weight gain during pregnancy. Studies have shown that gestational overweight is associated with complications in pregnancy and birthing as well as short-term and long-term impacts on neonatal outcome in childhood and adulthood.

Methods: Five hundred and ninety-one women visiting our tertiary perinatal center in 2014 were analyzed for antenatal BMI, gestational weight gain, as well as pregnancy outcome and complication together with neonatal weight and outcome. Pregnancy weight gain was assessed based on the IOM guidelines (Institute of Medicine) issued in 2009.

Results: Twenty-nine percent of our population was overweight with a BMI of more than 25.0. The general weight gain was in every BMI group similar (median ranging from 12.0 to 14.0 kg). Approximately one third gained more than the appropriate amount (37%, P<0.001). Women with more gestational weight were at risk of labor induction (55.0% vs. 45.7% labor induction in total, P=0.007). Strikingly, those patients were found to have significantly higher rates of secondary cesarean section (22.4% vs. 15.4%) and decreased chances of spontaneous vaginal birth (57.5% vs. 61.4%) (P=0.008). Furthermore women with a pregnancy weight gain in excess of the guidelines gave birth to neonates with a higher birth weight (>75.centile, 28.3% vs. 21.3%, P<0.001).

Conclusions: Altogether, one third of the analyzed population is already overweight or obese when entering pregnancy. A higher gestational weight gain than the recommended amount was found in 37% of cases. We found an association with pregnancy and birthing complications as well as higher infant weight. This highlights the importance of preconceptive and prenatal advice, and if necessary, intervention on BMI and weight gain.
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May 2016

Fetomaternal hemorrhage (FMH), an update: review of literature and an illustrative case.

Arch Gynecol Obstet 2015 Sep 17;292(3):595-602. Epub 2015 Mar 17.

Department of Obstetrics and Gynecology, Vivantes Klinikum im Friedrichshain, Berlin, Germany,

Background: Blood trafficking from fetus to mother and vice versa is a well-known physiological event that occurs at any stage in pregnancy. If the fetus looses high blood quantities to the maternal blood stream it becomes symptomatic. These symptoms can vary from cardiovascular distress to fetal death.

Materials And Methods: We give a review of current literature on Fetomaternal hemorrhage (FMH).

Conclusion: This article highlights the importance of physician's awareness on detecting this rare but life threatening entity with both severe consequences for mother and neonate. The traditional measurement of FMH and the co-usage of alpha-fetoprotein are debated. To conclude we describe and discuss an illustrative case of FMH. This article gives an applicatory overview of symptoms, diagnostics and treatment of FMH to facilitate physicians to detect this disease precociously.
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September 2015