Publications by authors named "Josef Mautner"

56Publications

The Epstein-Barr Virus Major Tegument Protein BNRF1 Is a Common Target of Cytotoxic CD4 T Cells.

J Virol 2020 Jul 16;94(15). Epub 2020 Jul 16.

Children's Hospital, School of Medicine, Technical University of Munich, Munich, Germany

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http://dx.doi.org/10.1128/JVI.00284-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375367PMC
July 2020

Progress in EBV Vaccines.

Front Oncol 2019 25;9:104. Epub 2019 Feb 25.

German Cancer Research Center (DKFZ), Heidelberg, Germany.

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https://www.frontiersin.org/article/10.3389/fonc.2019.00104/
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http://dx.doi.org/10.3389/fonc.2019.00104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398348PMC
February 2019

Immunization with a recombinant fusion protein protects mice against Helicobacter pylori infection.

Vaccine 2018 08 21;36(34):5124-5132. Epub 2018 Jul 21.

Department of Pathology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.

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http://dx.doi.org/10.1016/j.vaccine.2018.07.033DOI Listing
August 2018

Antibodies conjugated with viral antigens elicit a cytotoxic T cell response against primary CLL ex vivo.

Leukemia 2019 01 20;33(1):88-98. Epub 2018 Jun 20.

German Cancer Research Center (DKFZ), Unit F100, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0160-7DOI Listing
January 2019

Epstein-Barr virus strain heterogeneity impairs human T-cell immunity.

Cancer Immunol Immunother 2018 Apr 27;67(4):663-674. Epub 2018 Jan 27.

Children's Hospital, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1007/s00262-018-2118-zDOI Listing
April 2018

Immunization with recombinant FliD confers protection against Helicobacter pylori infection in mice.

Mol Immunol 2018 02 8;94:176-182. Epub 2018 Jan 8.

Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran; Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran.

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http://dx.doi.org/10.1016/j.molimm.2018.01.001DOI Listing
February 2018

Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing.

J Exp Med 2016 09 12;213(10):2065-80. Epub 2016 Sep 12.

Research Unit Gene Vectors, Helmholtz Zentrum München, German Research Center for Environmental Health, Partner site Munich, Germany, D-81377 Munich, Germany German Centre for Infection Research (DZIF), Partner site Munich, Germany, D-81377 Munich, Germany

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http://dx.doi.org/10.1084/jem.20160248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030804PMC
September 2016

A Diverse Repertoire of CD4 T Cells Targets the Immediate-Early 1 Protein of Human Cytomegalovirus.

Front Immunol 2015 25;6:598. Epub 2015 Nov 25.

Clinical Cooperation Group Immunooncology, Helmholtz Zentrum München and Ludwig-Maximilians-Universität , Munich , Germany ; Research Group Host Control of Viral Latency and Reactivation, Helmholtz Zentrum München , Munich , Germany ; German Research Center for Infection Research (DZIF) , Munich , Germany.

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http://dx.doi.org/10.3389/fimmu.2015.00598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658442PMC
December 2015

Simultaneous immunization of mice with Omp31 and TF provides protection against Brucella melitensis infection.

Vaccine 2015 Oct 16;33(42):5532-5538. Epub 2015 Sep 16.

Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran; Immunology Research Center, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.09.013DOI Listing
October 2015

Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins.

Mult Scler 2016 Mar 3;22(3):279-91. Epub 2015 Jun 3.

Department of Viroscience, Erasmus Medical Center, Rotterdam, the Netherlands/Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Hannover, Germany

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http://dx.doi.org/10.1177/1352458515588581DOI Listing
March 2016

Antigen-armed antibodies targeting B lymphoma cells effectively activate antigen-specific CD4+ T cells.

Blood 2015 Mar 7;125(10):1601-10. Epub 2015 Jan 7.

German Cancer Research Centre (DKFZ) Unit F100, Heidelberg, Germany; Institut National de la Santé et de la Recherche Médicale Unit U1074, Heidelberg, Germany; German Centre for Infection Research (DZIF), Heidelberg, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-07-59
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http://dx.doi.org/10.1182/blood-2014-07-591412DOI Listing
March 2015

Polyubiquitination of lysine-48 is an essential but indirect signal for MHC class I antigen processing.

Eur J Immunol 2015 Mar 15;45(3):716-27. Epub 2015 Jan 15.

Clinical Cooperation Group Pediatric Tumor Immunology, Children's Hospital, Technische Universität München, Munich, Germany; Helmholtz ZentrumMünchen, Munich, Germany; German Centre for Infection Research (DZIF), Germany.

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http://dx.doi.org/10.1002/eji.201444830DOI Listing
March 2015

Immunization of mice with a novel recombinant molecular chaperon confers protection against Brucella melitensis infection.

Vaccine 2014 Nov 19;32(49):6659-66. Epub 2014 Sep 19.

Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran; Immunology Research Center, Iran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.09.013DOI Listing
November 2014

Virus and autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated post-transplant lymphoproliferative disorders.

PLoS Pathog 2014 May 22;10(5):e1004068. Epub 2014 May 22.

Clinical Cooperation Group Pediatric Tumor Immunology, Children's Hospital, Technische Universität München, Munich, Germany; Helmholtz Zentrum München, Munich, Germany; German Centre for Infection Research (DZIF), Munich, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1004068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031221PMC
May 2014

Targeting high-grade B cell lymphoma with CD19-specific T cells.

Int J Cancer 2014 Sep 20;135(5):1153-64. Epub 2014 Feb 20.

Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany.

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http://dx.doi.org/10.1002/ijc.28760DOI Listing
September 2014

Presentation of an immunodominant immediate-early CD8+ T cell epitope resists human cytomegalovirus immunoevasion.

PLoS Pathog 2013 23;9(5):e1003383. Epub 2013 May 23.

Clinical Cooperation Group Immunooncology, Department of Medicine III, Klinikum der Universität München, Helmholtz Zentrum München, Munich, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1003383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662661PMC
December 2013

Mature proteins derived from Epstein-Barr virus fail to feed into the MHC class I antigenic pool.

Eur J Immunol 2012 Dec 16;42(12):3167-73. Epub 2012 Oct 16.

Clinical Cooperation Group Pediatric Tumor Immunology, Helmholtz-Zentrum München, München, Germany.

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http://dx.doi.org/10.1002/eji.201242627DOI Listing
December 2012

Humanized c-Myc mouse.

PLoS One 2012 31;7(7):e42021. Epub 2012 Jul 31.

Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Center Munich, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042021PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409231PMC
January 2013

Burkitt lymphoma: the role of Epstein-Barr virus revisited.

Br J Haematol 2012 Mar;156(6):719-29

Institute of Clinical Molecular Biology and Tumour Genetics, German Research Centre for Environmental Health, Helmholtz Zentrum München, Marchioninistrasse 25, Munich, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2011.09007.xDOI Listing
March 2012

The role of virus-specific CD4+ T cells in the control of Epstein-Barr virus infection.

Eur J Cell Biol 2012 Jan 1;91(1):31-5. Epub 2011 Apr 1.

Clinical Cooperation Group, Pediatric Tumor Immunology, Helmholtz-Zentrum München, Marchioninistrasse 25, Munich, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S017193351100017
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http://dx.doi.org/10.1016/j.ejcb.2011.01.007DOI Listing
January 2012

Autophagy in herpesvirus immune control and immune escape.

Herpesviridae 2011 Jan 5;2(1). Epub 2011 Jan 5.

School of Cancer Sciences and Medical Research Council Centre for Immune Regulation, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1186/2042-4280-2-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063195PMC
January 2011

Pancreatic cancers require autophagy for tumor growth.

Genes Dev 2011 Apr 15;25(7):717-29. Epub 2011 Mar 15.

Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gad.2016111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070934PMC
April 2011

Virus-specific cytotoxic CD4+ T cells for the treatment of EBV-related tumors.

J Immunol 2010 May 12;184(10):5895-902. Epub 2010 Apr 12.

Department of Oncology and Surgical Sciences, University of Padova, Italy.

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http://dx.doi.org/10.4049/jimmunol.0902850DOI Listing
May 2010

Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells.

Blood 2010 Apr 26;115(14):2960-70. Epub 2010 Jan 26.

Clinical Cooperation Group Molecular Oncology, Helmholtz Zentrum München and Ludwig-Maximilians-Universität, Munich, Germany.

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http://dx.doi.org/10.1182/blood-2009-08-236356DOI Listing
April 2010

Epstein-Barr viruses that express a CD21 antibody provide evidence that gp350's functions extend beyond B-cell surface binding.

J Virol 2010 Jan 4;84(2):1139-47. Epub 2009 Nov 4.

German Cancer Research Center, ATV-F100, Im Neuenheimer Feld 242, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1128/JVI.01953-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798361PMC
January 2010

Contribution of viral recombinants to the study of the immune response against the Epstein-Barr virus.

Semin Cancer Biol 2008 Dec 30;18(6):409-15. Epub 2008 Sep 30.

German Cancer Research Center, Department of Virus Associated Tumours, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.semcancer.2008.09.001DOI Listing
December 2008

Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export.

Eur J Immunol 2008 Aug;38(8):2090-5

Klinische Kooperationsgruppe, GSF-Institut für Klinische Molekularbiologie und Tumorgenetik, München, Germany.

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http://dx.doi.org/10.1002/eji.200737900DOI Listing
August 2008

Standardized and highly efficient expansion of Epstein-Barr virus-specific CD4+ T cells by using virus-like particles.

J Virol 2008 Apr 13;82(8):3903-11. Epub 2008 Feb 13.

Children's Hospital, University of Technology, Kölner Platz 1, D-80804 Munich, Germany.

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http://dx.doi.org/10.1128/JVI.02227-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2293016PMC
April 2008

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.

Authors:
Daniel J Klionsky Hagai Abeliovich Patrizia Agostinis Devendra K Agrawal Gjumrakch Aliev David S Askew Misuzu Baba Eric H Baehrecke Ben A Bahr Andrea Ballabio Bruce A Bamber Diane C Bassham Ettore Bergamini Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Dale E Bredesen Jeffrey L Brodsky John H Brumell Ulf T Brunk Wilfried Bursch Nadine Camougrand Eduardo Cebollero Francesco Cecconi Yingyu Chen Lih-Shen Chin Augustine Choi Charleen T Chu Jongkyeong Chung Peter G H Clarke Robert S B Clark Steven G Clarke Corinne Clavé John L Cleveland Patrice Codogno María I Colombo Ana Coto-Montes James M Cregg Ana Maria Cuervo Jayanta Debnath Francesca Demarchi Patrick B Dennis Phillip A Dennis Vojo Deretic Rodney J Devenish Federica Di Sano J Fred Dice Marian Difiglia Savithramma Dinesh-Kumar Clark W Distelhorst Mojgan Djavaheri-Mergny Frank C Dorsey Wulf Dröge Michel Dron William A Dunn Michael Duszenko N Tony Eissa Zvulun Elazar Audrey Esclatine Eeva-Liisa Eskelinen László Fésüs Kim D Finley José M Fuentes Juan Fueyo Kozo Fujisaki Brigitte Galliot Fen-Biao Gao David A Gewirtz Spencer B Gibson Antje Gohla Alfred L Goldberg Ramon Gonzalez Cristina González-Estévez Sharon Gorski Roberta A Gottlieb Dieter Häussinger You-Wen He Kim Heidenreich Joseph A Hill Maria Høyer-Hansen Xun Hu Wei-Pang Huang Akiko Iwasaki Marja Jäättelä William T Jackson Xuejun Jiang Shengkan Jin Terje Johansen Jae U Jung Motoni Kadowaki Chanhee Kang Ameeta Kelekar David H Kessel Jan A K W Kiel Hong Pyo Kim Adi Kimchi Timothy J Kinsella Kirill Kiselyov Katsuhiko Kitamoto Erwin Knecht Masaaki Komatsu Eiki Kominami Seiji Kondo Attila L Kovács Guido Kroemer Chia-Yi Kuan Rakesh Kumar Mondira Kundu Jacques Landry Marianne Laporte Weidong Le Huan-Yao Lei Michael J Lenardo Beth Levine Andrew Lieberman Kah-Leong Lim Fu-Cheng Lin Willisa Liou Leroy F Liu Gabriel Lopez-Berestein Carlos López-Otín Bo Lu Kay F Macleod Walter Malorni Wim Martinet Ken Matsuoka Josef Mautner Alfred J Meijer Alicia Meléndez Paul Michels Giovanni Miotto Wilhelm P Mistiaen Noboru Mizushima Baharia Mograbi Iryna Monastyrska Michael N Moore Paula I Moreira Yuji Moriyasu Tomasz Motyl Christian Münz Leon O Murphy Naweed I Naqvi Thomas P Neufeld Ichizo Nishino Ralph A Nixon Takeshi Noda Bernd Nürnberg Michinaga Ogawa Nancy L Oleinick Laura J Olsen Bulent Ozpolat Shoshana Paglin Glen E Palmer Issidora Papassideri Miles Parkes David H Perlmutter George Perry Mauro Piacentini Ronit Pinkas-Kramarski Mark Prescott Tassula Proikas-Cezanne Nina Raben Abdelhaq Rami Fulvio Reggiori Bärbel Rohrer David C Rubinsztein Kevin M Ryan Junichi Sadoshima Hiroshi Sakagami Yasuyoshi Sakai Marco Sandri Chihiro Sasakawa Miklós Sass Claudio Schneider Per O Seglen Oleksandr Seleverstov Jeffrey Settleman John J Shacka Irving M Shapiro Andrei Sibirny Elaine C M Silva-Zacarin Hans-Uwe Simon Cristiano Simone Anne Simonsen Mark A Smith Katharina Spanel-Borowski Vickram Srinivas Meredith Steeves Harald Stenmark Per E Stromhaug Carlos S Subauste Seiichiro Sugimoto David Sulzer Toshihiko Suzuki Michele S Swanson Ira Tabas Fumihiko Takeshita Nicholas J Talbot Zsolt Tallóczy Keiji Tanaka Kozo Tanaka Isei Tanida Graham S Taylor J Paul Taylor Alexei Terman Gianluca Tettamanti Craig B Thompson Michael Thumm Aviva M Tolkovsky Sharon A Tooze Ray Truant Lesya V Tumanovska Yasuo Uchiyama Takashi Ueno Néstor L Uzcátegui Ida van der Klei Eva C Vaquero Tibor Vellai Michael W Vogel Hong-Gang Wang Paul Webster John W Wiley Zhijun Xi Gutian Xiao Joachim Yahalom Jin-Ming Yang George Yap Xiao-Ming Yin Tamotsu Yoshimori Li Yu Zhenyu Yue Michisuke Yuzaki Olga Zabirnyk Xiaoxiang Zheng Xiongwei Zhu Russell L Deter

Autophagy 2008 Feb 21;4(2):151-75. Epub 2007 Nov 21.

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109-2216, USA.

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http://www.dwalab.ca/common/pdf/cdd200944a.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654259PMC
http://dx.doi.org/10.4161/auto.5338DOI Listing
February 2008

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy.

PLoS One 2007 Jul 4;2(7):e583. Epub 2007 Jul 4.

Clinical Cooperation Group, Institute for Clinical and Molecular Biology, GSF-National Research Center for Environment and Health, Munich, Germany; Children's Hospital, Hematology-Oncology, University of Technology, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0000583PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894652PMC
July 2007

The infectious kiss: newly infected B cells deliver Epstein-Barr virus to epithelial cells.

Proc Natl Acad Sci U S A 2006 May 1;103(19):7201-2. Epub 2006 May 1.

Institute of Clinical Molecular Biology and Tumor Genetics, GSF-National Research Center for Environment and Health, Marchioninistrasse 25, D-81377 Munich, Germany.

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http://dx.doi.org/10.1073/pnas.0602077103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464320PMC
May 2006

Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins.

J Exp Med 2006 Apr 20;203(4):995-1006. Epub 2006 Mar 20.

Clinical Cooperation Group, Institute for Clinical and Molecular Biology, GSF-National Research Center for Environment and Health, Technical University Munich, 80804 Munich, Germany.

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http://dx.doi.org/10.1084/jem.20051287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118290PMC
April 2006

Direct mapping of MHC class II epitopes.

J Immunol Methods 2005 Nov 31;306(1-2):28-39. Epub 2005 Aug 31.

Clinical Cooperation Group, Children's Hospital, Hematology-Oncology, Technical University Munich, Kölner Platz 1, D-80804 Munich, Germany.

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http://dx.doi.org/10.1016/j.jim.2005.07.020DOI Listing
November 2005

Epstein-Barr virus latent membrane protein 2A mimics B-cell receptor-dependent virus reactivation.

J Gen Virol 2005 Mar;86(Pt 3):551-559

GSF-Research Center for Environment and Health, Institute for Clinical Molecular Biology and Tumor Genetics, Marchioninistrasse 25, D-81377 Munich, Germany.

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http://dx.doi.org/10.1099/vir.0.80440-0DOI Listing
March 2005

Diverse CD8+ T-cell responses to renal cell carcinoma antigens in patients treated with an autologous granulocyte-macrophage colony-stimulating factor gene-transduced renal tumor cell vaccine.

Cancer Res 2005 Feb;65(3):1079-88

Division of Immunology and Hematopoiesis, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA.

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February 2005

Tumor-specific CD4+ T cells from a patient with renal cell carcinoma recognize diverse shared antigens.

Int J Cancer 2005 Jul;115(5):752-9

Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://doi.wiley.com/10.1002/ijc.20927
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http://dx.doi.org/10.1002/ijc.20927DOI Listing
July 2005

Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells.

Eur J Immunol 2004 Sep;34(9):2500-9

Clinical Cooperation Group, Institute for Clinical and Molecular Biology, GSF-National Research Center for Environment and Health, Munich, Germany.

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http://dx.doi.org/10.1002/eji.200324794DOI Listing
September 2004

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

J Gen Virol 2004 Aug;85(Pt 8):2347-2356

Klinische Kooperationsgruppe, Pädiatrische Tumorimmunologie, Kinderklinik, Universitätsklinikum der Technischen Universität München, Marchioninistr. 25, D-81377 München, Germany.

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http://dx.doi.org/10.1099/vir.0.79958-0DOI Listing
August 2004

Efficient generation and expansion of antigen-specific CD4+ T cells by recombinant influenza viruses.

Eur J Immunol 2003 Dec;33(12):3331-41

Klinische Kooperationsgruppe, Pädiatrische Tumorimmunologie, Kinderklinik, Universitätsklinikum der Technischen Universität München, München, Germany.

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http://dx.doi.org/10.1002/eji.200324342DOI Listing
December 2003

Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy.

Eur J Immunol 2003 May;33(5):1250-9

Klinische Kooperationsgruppe, GSF-Institut für Klinische Molekularbiologie, Munich, Germany.

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http://doi.wiley.com/10.1002/eji.200323730
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http://dx.doi.org/10.1002/eji.200323730DOI Listing
May 2003

Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library.

Int J Cancer 2002 Aug;100(6):669-77

Hämatologie-Onkologie, Kinderklinik der Technische Universität München, Kölner Platz 1, 80804 Munich, Germany.

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http://dx.doi.org/10.1002/ijc.10550DOI Listing
August 2002

MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells.

Proc Natl Acad Sci U S A 2002 Apr 26;99(7):4550-5. Epub 2002 Mar 26.

Institut für Klinische Molekularbiologie und Tumorgenetik, GSF-Forschungszentrum für Umwelt und Gesundheit, Marchioninistrasse 25, D-81377 München, Germany.

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http://dx.doi.org/10.1073/pnas.072495599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123685PMC
April 2002