Jose Manuel Fernandez-Real

Jose Manuel Fernandez-Real

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Jose Manuel Fernandez-Real

Jose Manuel Fernandez-Real

Publications by authors named "Jose Manuel Fernandez-Real"

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A Modular Safety System for an Insulin Dose Recommender: A Feasibility Study.

J Diabetes Sci Technol 2020 Jan 22;14(1):87-96. Epub 2019 May 22.

Centre for Bio-Inspired Technology, Department of Electrical and Electronic Engineering, Imperial College London, London, UK.

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http://dx.doi.org/10.1177/1932296819851135DOI Listing
January 2020

Plasma Phospholipids with Long Chain Polyunsaturated Fatty Acids and Dihydroceramides at the Crossroads of Iron Stores and Insulin Resistance.

Mol Nutr Food Res 2020 Jan 16:e1901055. Epub 2020 Jan 16.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1002/mnfr.201901055DOI Listing
January 2020

The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue.

Rev Endocr Metab Disord 2019 12;20(4):387-397

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1007/s11154-019-09523-xDOI Listing
December 2019

Consider the microbiome in the equation! They were here before us...and hosted us!

Rev Endocr Metab Disord 2019 12;20(4):383-385

INSERM, Toulouse, France.

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http://dx.doi.org/10.1007/s11154-019-09538-4DOI Listing
December 2019

Microbiota impacts on chronic inflammation and metabolic syndrome - related cognitive dysfunction.

Rev Endocr Metab Disord 2019 12;20(4):473-480

Department of Diabetes, Endocrinology and Nutrition, Dr. Josep Trueta University Hospital, Girona Biomedical Research Institute [IdibGi], Carretera de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1007/s11154-019-09537-5DOI Listing
December 2019

Exploration of the microbiota and metabolites within body fluids could pinpoint novel disease mechanisms.

FEBS J 2019 Nov 11. Epub 2019 Nov 11.

Department of Endocrinology, Diabetes and Nutrition, Hospital of Girona 'Dr Josep Trueta', University of Girona, Girona Biomedical Research Institute (IdibGi), Spain.

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http://dx.doi.org/10.1111/febs.15130DOI Listing
November 2019

Preoperative Circulating Succinate Levels as a Biomarker for Diabetes Remission After Bariatric Surgery.

Diabetes Care 2019 Oct 2;42(10):1956-1965. Epub 2019 Aug 2.

Institut d'Investigació Sanitària Pere Virgili, Endocrinology and Nutrition Service, Hospital Universitari de Tarragona Joan XXIII, Tarragona, Spain

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http://dx.doi.org/10.2337/dc19-0114DOI Listing
October 2019

Combining metabolic profiling of plasma and faeces as a fingerprint of insulin resistance in obesity.

Clin Nutr 2019 Oct 25. Epub 2019 Oct 25.

CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Diabetes, Endocrinology and Nutrition (UDEN), Institut d'Investigació Biomédica de Girona (IDIBGI), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.10.022DOI Listing
October 2019

Hydrogen sulfide impacts on inflammation-induced adipocyte dysfunction.

Food Chem Toxicol 2019 Sep 30;131:110543. Epub 2019 May 30.

Department of Diabetes, Endocrinology and Nutrition, Hospital of Girona 'Dr Josep Trueta'Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain; Department of Medicine, Universitat de Girona, Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2019.05.051DOI Listing
September 2019

Iron influences on the Gut-Brain axis and development of type 2 diabetes.

Crit Rev Food Sci Nutr 2019 17;59(3):443-449. Epub 2017 Oct 17.

c Research Area for multifactorial diseases, Bambino Gesù Children's Hospital and Research Institute, Research Unit for Multifactorial Disease , Rome , Italy.

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http://dx.doi.org/10.1080/10408398.2017.1376616DOI Listing
August 2019

Adipose tissue TSH as a new modulator of human adipocyte mitochondrial function.

Int J Obes (Lond) 2019 08 11;43(8):1611-1619. Epub 2018 Sep 11.

Department of Diabetes, Endocrinology and Nutrition Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1038/s41366-018-0203-1DOI Listing
August 2019

Recommendations for the detection, diagnosis and follow-up of patients with non-alcoholic fatty liver disease in primary and hospital care.

Med Clin (Barc) 2019 Aug 6;153(4):169-177. Epub 2019 Jun 6.

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) Instituto de Salud Carlos III, España; Servei d'Hepatologia, Hospital Clínic, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, España; Grupo de trabajo sobre «Hígado graso no alcohólico» de la Societat Catalana de Digestologia, Barcelona, España.

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http://dx.doi.org/10.1016/j.medcli.2019.01.030DOI Listing
August 2019

Circulating Irisin and Myostatin as Markers of Muscle Strength and Physical Condition in Elderly Subjects.

Front Physiol 2019 10;10:871. Epub 2019 Jul 10.

Department of Diabetes, Endocrinology and Nutrition, Girona Biomedical Research Institute (IdIBGi), CIBEROBN (CB06/03/010) and Carlos III Health Institute (ISCIII), Girona, Spain.

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http://dx.doi.org/10.3389/fphys.2019.00871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637304PMC
July 2019

Glycated Hemoglobin, but not Insulin Sensitivity, is Associated with Memory in Subjects with Obesity.

Obesity (Silver Spring) 2019 06 15;27(6):932-942. Epub 2019 Apr 15.

Department of Diabetes, Endocrinology and Nutrition, Girona Biomedical Research Institute, Dr. Josep Trueta University Hospital, Center for Physiopathology of Obesity and Nutrition, Girona, Spain.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/oby.22457
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http://dx.doi.org/10.1002/oby.22457DOI Listing
June 2019

Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition.

Acta Diabetol 2019 May 19;56(5):569-579. Epub 2019 Mar 19.

Department of Diabetes, Endocrinology and Nutrition, Hospital of Girona "Dr Josep Trueta", Institut d'Investigació Biomèdica de Girona (IDIBGI), Avinguda de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1007/s00592-019-01313-wDOI Listing
May 2019

Circulating Soluble CD36 is Similar in Type 1 and Type 2 Diabetes Mellitus versus Non-Diabetic Subjects.

J Clin Med 2019 May 18;8(5). Epub 2019 May 18.

Department of Endocrinology & Nutrition, University, Hospital de la Santa Creu i Sant Pau & Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), 08041 Barcelona, Spain.

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http://dx.doi.org/10.3390/jcm8050710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571689PMC
May 2019

Iron Status and Metabolically Unhealthy Obesity in Prepubertal Children.

Obesity (Silver Spring) 2019 04 28;27(4):636-644. Epub 2019 Feb 28.

Department of Diabetes, Endocrinology and Nutrition, Department of Medical Sciences, Faculty of Medicine, Girona Institute for Biomedical Research, Spanish Biomedical Research Center in Physiopathology of Obesity and Nutrition and National Institute of Health Carlos III, Girona, Spain.

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http://dx.doi.org/10.1002/oby.22425DOI Listing
April 2019

Adipose Tissue Expansion by Overfeeding Healthy Men Alters Iron Gene Expression.

J Clin Endocrinol Metab 2019 03;104(3):688-696

Univ-Lyon, CarMeN Laboratory, and Centre de Recherche en Nutrition Humaine Rhône-Alpes, Université Claude Bernard Lyon1, Pierre Benite, France.

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https://academic.oup.com/jcem/advance-article/doi/10.1210/jc
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http://dx.doi.org/10.1210/jc.2018-01169DOI Listing
March 2019

The complement system is dysfunctional in metabolic disease: Evidences in plasma and adipose tissue from obese and insulin resistant subjects.

Semin Cell Dev Biol 2019 01 28;85:164-172. Epub 2017 Oct 28.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.10.025DOI Listing
January 2019

Carnosine supplementation reduces plasma soluble transferrin receptor in healthy overweight or obese individuals: a pilot randomised trial.

Amino Acids 2019 Jan 22;51(1):73-81. Epub 2018 Aug 22.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, 43-51 Kanooka Grove, Clayton, Melbourne, VIC, 3168, Australia.

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http://dx.doi.org/10.1007/s00726-018-2623-6DOI Listing
January 2019

Obesity status influences the relationship among serum osteocalcin, iron stores and insulin sensitivity.

Clin Nutr 2018 12 6;37(6 Pt A):2091-2096. Epub 2017 Oct 6.

Department of Diabetes, Endocrinology and Nutrition (UDEN), Institut d'Investigació Biomédica de Girona (IdIBGi), CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBERobn, CB06/03/0010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2017.10.001DOI Listing
December 2018

Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.

Cell Physiol Biochem 2018 16;51(1):142-153. Epub 2018 Nov 16.

Department of Diabetes, Endocrinology and Nutrition Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1159/000495170DOI Listing
December 2018

Ferritin, metabolic syndrome and its components: A systematic review and meta-analysis.

Atherosclerosis 2018 08 23;275:97-106. Epub 2018 May 23.

Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.05.043DOI Listing
August 2018

Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility.

Cell Rep 2018 08;24(8):2005-2012.e7

The University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge CB2 0QQ, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.07.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113930PMC
August 2018

Decreased iron stores are associated with cardiovascular disease in patients with type 2 diabetes both cross-sectionally and longitudinally.

Atherosclerosis 2018 05 21;272:193-199. Epub 2018 Mar 21.

Department of Diabetes, Endocrinology and Nutrition, Institut D'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.03.028DOI Listing
May 2018

Single Nucleotide Polymorphism relevance learning with Random Forests for Type 2 diabetes risk prediction.

Artif Intell Med 2018 04 22;85:43-49. Epub 2017 Sep 22.

Biomedical Research Institute of Girona, Avda. de França, s/n, 17007 Girona, Spain; CIBERobn Pathophysiology of Obesity and Nutrition, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.artmed.2017.09.005DOI Listing
April 2018

Low-grade Inflammatory Marker Profile May Help to Differentiate Patients With LADA, Classic Adult-Onset Type 1 Diabetes, and Type 2 Diabetes.

Diabetes Care 2018 04 22;41(4):862-868. Epub 2018 Jan 22.

Department of Endocrinology and Nutrition, Health Sciences Research Institute, University Hospital Germans Trias i Pujol, Badalona, Spain

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http://dx.doi.org/10.2337/dc17-1662DOI Listing
April 2018

LncRNAs in Adipose Tissue from Obese and Insulin-Resistant Subjects: New Targets for Therapy?

EBioMedicine 2018 04 21;30:10-11. Epub 2018 Mar 21.

Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Diabetes, Endocrinology, and Nutrition (UDEN), Institut d'Investigació Biomédica de Girona (IdIBGi), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952408PMC
April 2018

Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin-Stimulated Glucose Uptake.

Mol Nutr Food Res 2018 03 20;62(5). Epub 2018 Feb 20.

Department of Molecular and Cellular Physiology, Institute of Translational Medicine, The University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1002/mnfr.201700917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887919PMC
March 2018

Gut Microbiota Interacts with Markers of Adipose Tissue Browning, Insulin Action and Plasma Acetate in Morbid Obesity.

Mol Nutr Food Res 2018 02 29;62(3). Epub 2017 Dec 29.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/mnfr.201700721DOI Listing
February 2018

Increased Small Intestine Expression of Non-Heme Iron Transporters in Morbidly Obese Patients With Newly Diagnosed Type 2 Diabetes.

Mol Nutr Food Res 2018 01 29;62(2). Epub 2017 Dec 29.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/mnfr.201700301DOI Listing
January 2018

miRNAs in cerebrospinal fluid identify patients with MS and specifically those with lipid-specific oligoclonal IgM bands.

Mult Scler 2017 Nov 9;23(13):1716-1726. Epub 2017 Jan 9.

Girona Neuroimmunology and Multiple Sclerosis Unit (UNIEM), Dr. Josep Trueta University Hospital and Girona Biomedical Research Institute (IDIBGI), Girona, Spain/Red Española de Esclerosis Múltiple (REEM), Madrid, Spain.

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http://dx.doi.org/10.1177/1352458516684213DOI Listing
November 2017

Hepatic iron content is independently associated with serum hepcidin levels in subjects with obesity.

Clin Nutr 2017 10 29;36(5):1434-1439. Epub 2016 Sep 29.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), Hospital Dr Josep Trueta, CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2016.09.022DOI Listing
October 2017

mRNA is linked to cholesterol metabolism in adipose tissue.

FASEB J 2017 10 23;31(10):4482-4491. Epub 2017 Jun 23.

Department of Diabetes, Endocrinology, and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Girona, Spain;

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http://dx.doi.org/10.1096/fj.201700161RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602896PMC
October 2017

Heme Biosynthetic Pathway is Functionally Linked to Adipogenesis via Mitochondrial Respiratory Activity.

Obesity (Silver Spring) 2017 10 31;25(10):1723-1733. Epub 2017 Aug 31.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III, Girona, Spain.

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http://dx.doi.org/10.1002/oby.21956DOI Listing
October 2017

The Gut Metagenome Changes in Parallel to Waist Circumference, Brain Iron Deposition, and Cognitive Function.

J Clin Endocrinol Metab 2017 08;102(8):2962-2973

Department of Diabetes, Endocrinology and Nutrition (UDEN), Girona Biomedical Research Institute (IDIBGI), CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBERobn, CB06/03/0010), Instituto de Salud Carlos III (ISCIII), Girona 17007, Spain.

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http://dx.doi.org/10.1210/jc.2017-00133DOI Listing
August 2017

Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism.

Sci Rep 2017 07 13;7(1):5305. Epub 2017 Jul 13.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), Hospital of Girona 'Dr JosepTrueta', Carretera de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1038/s41598-017-05597-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509649PMC
July 2017

Physiology and role of irisin in glucose homeostasis.

Nat Rev Endocrinol 2017 06 17;13(6):324-337. Epub 2017 Feb 17.

Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/nrendo.2016.221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878942PMC
June 2017

HMOX1 as a marker of iron excess-induced adipose tissue dysfunction, affecting glucose uptake and respiratory capacity in human adipocytes.

Diabetologia 2017 05 27;60(5):915-926. Epub 2017 Feb 27.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), Hospital of Girona 'Dr Josep Trueta', Carretera de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1007/s00125-017-4228-0DOI Listing
May 2017

Modulation of SHBG binding to testosterone and estradiol by sex and morbid obesity.

Eur J Endocrinol 2017 Apr 11;176(4):393-404. Epub 2017 Jan 11.

Department of Biochemistry and Molecular Biomedicine; Faculty of BiologyUniversity of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1530/EJE-16-0834DOI Listing
April 2017

Thyroid hormones induce browning of white fat.

J Endocrinol 2017 02 2;232(2):351-362. Epub 2016 Dec 2.

Department of PhysiologyCIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain

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http://dx.doi.org/10.1530/JOE-16-0425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292977PMC
February 2017

Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature.

Obesity (Silver Spring) 2017 02 21;25(2):391-400. Epub 2016 Dec 21.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/oby.21711DOI Listing
February 2017

Gestational diabetes is associated with changes in placental microbiota and microbiome.

Pediatr Res 2016 12 4;80(6):777-784. Epub 2016 Aug 4.

Department of Endocrinology, Dr. Josep Trueta Hospital and Girona Institute for Biomedical Research and CIBERobn, Girona, Spain.

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http://dx.doi.org/10.1038/pr.2016.155DOI Listing
December 2016

Lower serum osteocalcin concentrations are associated with brain microstructural changes and worse cognitive performance.

Clin Endocrinol (Oxf) 2016 May 14;84(5):756-63. Epub 2015 Dec 14.

Department of Diabetes, Endocrinology and Nutrition, Girona Biomedical Research Institute (IDIBGI), Hospital Universitari de Girona Dr Josep Trueta, and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Girona, Spain.

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http://dx.doi.org/10.1111/cen.12954DOI Listing
May 2016

Circulating irisin levels are positively associated with metabolic risk factors in sedentary subjects.

PLoS One 2015 21;10(4):e0124100. Epub 2015 Apr 21.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124100PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405583PMC
April 2016

Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity.

Diabetologia 2016 Apr 2;59(4):822-32. Epub 2016 Feb 2.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), Hospital of Girona 'Dr Josep Trueta', Carretera de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1007/s00125-016-3863-1DOI Listing
April 2016

Obesity Is Associated With Gene Expression and Imaging Markers of Iron Accumulation in Skeletal Muscle.

J Clin Endocrinol Metab 2016 Mar 14;101(3):1282-9. Epub 2016 Jan 14.

Department of Diabetes, Endocrinology and Nutrition (J.M.M.-N., G.X., F.O., W.R., J.M.F.-R.), Institut d'Investigació Biomèdica de Girona, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CB06/03/010) and Instituto de Salud Carlos III, Girona, 17007 Spain; Department of Radiology (G.B., J.P.), Girona Biomedical Research Institute, Diagnostic Imaging Institute, Girona, 17007 Spain; Department of Metabolic Diseases (M.K.-K., M.Ste., N.M., M.Str), Medical University of Białystok, 15-089 Białystok, Poland; and Department of Prophylaxis of Metabolic Diseases (M.K.-K., M.Ste., N.M., M.Str), Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-747 Olsztyn, Poland.

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http://dx.doi.org/10.1210/jc.2015-3303DOI Listing
March 2016

Adipose tissue R2* signal is increased in subjects with obesity: A preliminary MRI study.

Obesity (Silver Spring) 2016 Feb 26;24(2):352-8. Epub 2015 Dec 26.

Department of Diabetes, Endocrinology and Nutrition, Institut D'investigació Biomèdica De Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto De Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/oby.21347DOI Listing
February 2016

Contrasting association of circulating sCD14 with insulin sensitivity in non-obese and morbidly obese subjects.

Mol Nutr Food Res 2016 Jan 20;60(1):103-9. Epub 2015 Jul 20.

University Hospital of Girona, Institut d'Investigació Biomèdica de Girona (IDIBGi) and CIBERobn Pathophysiology of Obesity and Nutrition, Spain.

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http://dx.doi.org/10.1002/mnfr.201500102DOI Listing
January 2016

Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels.

Arterioscler Thromb Vasc Biol 2016 Jan 19;36(1):174-80. Epub 2015 Nov 19.

From the Girona Institute for Biomedical Research, Girona, Spain (A.P.-P., M.M., G.C.-B., J.B., W.R., A.L.-B., J.M.F.-R.); Department of Physical Therapy, EUSES University School (A.P.-P.) and TransLab Research Group, Department of Medical Sciences, Faculty of Medicine (A.L.-B.), University of Girona, Girona, Spain; Pediatrics, Dr. JosepTrueta Hospital, Girona, Spain (A.P.-P., G.C.-B., J.B., A.L.-B.); and Department of Diabetes, Endocrinology, CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain (M.M., W.R., J.M.F.-R.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306396DOI Listing
January 2016

CISD1 in association with obesity-associated dysfunctional adipogenesis in human visceral adipose tissue.

Obesity (Silver Spring) 2016 Jan;24(1):139-47

Department of Diabetes, Endocrinology and Nutrition, Institut D'investigació Biomèdica De Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto De Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/oby.21334DOI Listing
January 2016

Breath gas concentrations mirror exposure to sevoflurane and isopropyl alcohol in hospital environments in non-occupational conditions.

J Breath Res 2016 Jan 29;10(1):016001. Epub 2016 Jan 29.

Servicio de Neurología, Complejo Hospitalario Universitario de A Coruña (CHUAC), A Coruña, Spain.

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http://dx.doi.org/10.1088/1752-7155/10/1/016001DOI Listing
January 2016

Circulating hepcidin in type 2 diabetes: A multivariate analysis and double blind evaluation of metformin effects.

Mol Nutr Food Res 2015 Dec 20;59(12):2460-70. Epub 2015 Oct 20.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/mnfr.201500310DOI Listing
December 2015

Gut Microbiota Interacts With Brain Microstructure and Function.

J Clin Endocrinol Metab 2015 Dec 7;100(12):4505-13. Epub 2015 Oct 7.

Department of Diabetes, Endocrinology and Nutrition (J.-M.F.-R., W.R.), Institut d'Investigació Biomédica de Girona, CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBERobn, CB06/03/0010) and Instituto de Salud Carlos III, Girona, 17007 Spain; Institut National de la Santé et de la Recherche Médicale (M.S., R.B.), Toulouse, France; Unité Mixte de Recherche 1048 (M.S., R.B.), Institut de Maladies Métaboliques et Cardiovasculaires, Université Paul Sabatier, F-31432 Toulouse Cedex 4, France; Girona Biomedical Research Institute, Department of Radiology-Institut de Diagnostic per la Imatge (G.B., J.P.), Hospital Universitari Dr Josep Trueta, Girona, 17007 Spain; Department of Computer Science, Applied Mathematics, and Statistics (J.D.-E.), University of Girona, Girona, 17071 Spain; Department of Psychiatry (F.F.-A.), University Hospital of Bellvitge-IDIBELL, Barcelona, CIBERobn, Instituto Salud Carlos III, Barcelona, 08908 Spain; and Nutren Group, Department of Experimental Medicine (M.P.-O.), PCiTAL-IRBLleida-Universitat de Lleida, Lleida, 25198 Spain.

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http://dx.doi.org/10.1210/jc.2015-3076DOI Listing
December 2015

Lean mass, and not fat mass, is an independent determinant of carotid intima media thickness in obese subjects.

Atherosclerosis 2015 Dec 9;243(2):493-8. Epub 2015 Sep 9.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.09.012DOI Listing
December 2015

Altered Circulating miRNA Expression Profile in Pregestational and Gestational Obesity.

J Clin Endocrinol Metab 2015 Nov 25;100(11):E1446-56. Epub 2015 Sep 25.

Departments of Pediatrics (G.C.-B., E.P.-G., A.L.-B., J.B.) and Gynecology (A.B.), Dr Josep Trueta Hospital, Department of Diabetes, Endocrinology, and Nutrition (F.-J.O., J.-M.F.-R.), Girona Institute for Biomedical Research (G.C.-B., E.P.-G., A.L.-B., J.B.), and Department of Physical Therapy (A.P.-P.), Escola Universitària de la Salut i l'Esport (EUSES), University of Girona, 17007 Girona, Spain; Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (F.-J.O., J.-M.F.-R.) and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (F.-J.O., J.-M.F.-R.), Instituto de Salud Carlos III, 28029 Madrid, Spain; Joint program on Computational Biology, Barcelona Supercomputing Center and Institut de Recerca Biomèdica de Barcelona (BSC-IRB) (J.-M.M., M.G.-M., D.T.), Barcelona Supercomputing Center, 08003 Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (D.T.), 08916 Barcelona, Spain; Institute of Legal Medicine of Catalonia (J.-M.M.-C.), 17001 Girona, Spain; Department of Development and Regeneration (F.D.Z.), University of Leuven, B-3000 Leuven, Belgium; and Department of Endocrinology (L.I.), Hospital Sant Joan de Déu, University of Barcelona, 08950 Esplugues, Barcelona, Spain.

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http://dx.doi.org/10.1210/jc.2015-2872DOI Listing
November 2015

Lipopolysaccharide binding protein is an adipokine involved in the resilience of the mouse adipocyte to inflammation.

Diabetologia 2015 Oct 23;58(10):2424-34. Epub 2015 Jul 23.

Section of Diabetes, Endocrinology and Nutrition, Hospital of Girona 'Dr Josep Trueta', Carretera de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1007/s00125-015-3692-7DOI Listing
October 2015

Obesity changes the human gut mycobiome.

Sci Rep 2015 Oct 12;5:14600. Epub 2015 Oct 12.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigacio´ Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://www.nature.com/articles/srep14600
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http://dx.doi.org/10.1038/srep14600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600977PMC
October 2015

Nonalcoholic fatty liver disease and age are strong indicators for atherosclerosis in morbid obesity.

Clin Endocrinol (Oxf) 2015 Aug 30;83(2):180-6. Epub 2015 Jan 30.

Department of Diabetes, Endocrinology and Nutrition, Girona Biomedical Research Institute (IDIBGI), Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain.

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http://dx.doi.org/10.1111/cen.12698DOI Listing
August 2015

Circulating hepcidin is independently associated with systolic blood pressure in apparently healthy individuals.

Arch Med Res 2015 Aug 6;46(6):507-13. Epub 2015 Aug 6.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.arcmed.2015.07.007DOI Listing
August 2015

Cytosolic aconitase activity sustains adipogenic capacity of adipose tissue connecting iron metabolism and adipogenesis.

FASEB J 2015 Apr 30;29(4):1529-39. Epub 2014 Dec 30.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona, CIBEROBN (CB06/03/010), and Instituto de Salud Carlos III, Girona, Spain

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http://dx.doi.org/10.1096/fj.14-258996DOI Listing
April 2015

Deleted in breast cancer 1 plays a functional role in adipocyte differentiation.

Am J Physiol Endocrinol Metab 2015 Apr 3;308(7):E554-61. Epub 2015 Feb 3.

Department of Diabetes, Endocrinology, and Nutrition, Institut d'Investigació Biomèdica de Girona, Centro de Investigacion Biomedica en Red Fisiopatologia de Obesidad y Nutricion (CB06/03/010) and Instituto de Salud Carlos III, Girona, Spain

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http://dx.doi.org/10.1152/ajpendo.00286.2014DOI Listing
April 2015

PRDM16 sustains white fat gene expression profile in human adipocytes in direct relation with insulin action.

Mol Cell Endocrinol 2015 Apr 7;405:84-93. Epub 2015 Feb 7.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010), Instituto de Salud Carlos III (ISCIII), Girona 17007, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.01.042DOI Listing
April 2015

Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants.

Clin Epigenetics 2015 24;7:49. Epub 2015 Apr 24.

Department of Diabetes, Endocrinology and Nutrition (UDEN), Institut d'Investigació Biomédica de Girona (IdIBGi), Avinguda de França s/n, 17007 Girona, Spain ; CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBERobn, CB06/03) and Instituto de Salud Carlos III (ISCIII), Sinesio Delgado 4, 28029 Madrid, Spain.

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http://dx.doi.org/10.1186/s13148-015-0083-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413548PMC
April 2015

Carotid pulse wave velocity by magnetic resonance imaging is increased in middle-aged subjects with the metabolic syndrome.

Int J Cardiovasc Imaging 2015 Mar 26;31(3):603-12. Epub 2014 Nov 26.

Department of Radiology, Girona Biomedical Research Institute (IDIBGI) - Diagnostic Imaging Institute (IDI), Hospital of Girona "Dr Josep Trueta", Av de França s/n, 17007, Girona, Spain,

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http://dx.doi.org/10.1007/s10554-014-0578-6DOI Listing
March 2015

Coxsackie and adenovirus receptor is increased in adipose tissue of obese subjects: a role for adenovirus infection?

J Clin Endocrinol Metab 2015 Mar 2;100(3):1156-63. Epub 2014 Dec 2.

Department of Diabetes, Endocrinology, and Nutrition (M.S., M.M., J.M.M.-N., F.O., W.R., J.M.F.-R.), Institut d'Investigació Biomèdica de Girona, CIBEROBN (CB06/03/010), and Instituto de Salud Carlos III, 17007 Girona, Spain; and Department of Pediatrics (J.B.), Institut d'Investigació Biomèdica de Girona, 17007 Girona, Spain.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-3791DOI Listing
March 2015

DBC1 is involved in adipocyte inflammation and is a possible marker of human adipose tissue senescence.

Obesity (Silver Spring) 2015 Mar 13;23(3):519-22. Epub 2015 Feb 13.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBEROBN (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Girona, Spain.

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http://dx.doi.org/10.1002/oby.20999DOI Listing
March 2015

Hypothalamic damage is associated with inflammatory markers and worse cognitive performance in obese subjects.

J Clin Endocrinol Metab 2015 Feb 25;100(2):E276-81. Epub 2014 Nov 25.

Department of Radiology (J.P., G.B., X.M., S.P.), Girona Biomedical Research Institute (IDIBGI), Hospital Universitari de Girona Dr Josep Trueta. Girona, Spain; Department of Computer Science, Applied Mathematics and Statistics (J.D.-i.-E.), University of Girona. Girona, Spain; Department of Diabetes, Endocrinology and Nutrition (J.P., G.X., W.R., J.M.F.-R.), IDIBGI, Hospital Universitari de Girona Dr Josep Trueta, and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn). Girona, Spain; and Department of Psychiatry (F.F.-A.), Hospital Universitari de Bellvitge, and CIBERobn, Barcelona, Spain.

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http://dx.doi.org/10.1210/jc.2014-2682DOI Listing
February 2015

Transducin-like enhancer of split 3 (TLE3) in adipose tissue is increased in situations characterized by decreased PPARγ gene expression.

J Mol Med (Berl) 2015 Jan 25;93(1):83-92. Epub 2014 Sep 25.

Department of Diabetes, Endocrinology and Nutrition (UDEN), Institut d'Investigació Biomèdica de Girona (IdIBGi), CIBERobn (CB06/03/010) and Instituto de Salud Carlos III (ISCIII), Carretera de França s/n, 17007, Girona, Spain,

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http://dx.doi.org/10.1007/s00109-014-1207-5DOI Listing
January 2015

Response to letter to the editor.

J Clin Endocrinol Metab 2015 Jan;100(1):L17

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http://dx.doi.org/10.1210/jc.2014-4213DOI Listing
January 2015

Olive oil phenolic compounds decrease the postprandial inflammatory response by reducing postprandial plasma lipopolysaccharide levels.

Food Chem 2014 Nov 24;162:161-71. Epub 2014 Apr 24.

Lipids and Atherosclerosis Unit, IMIBIC/Reina Sofia University Hospital/University of Cordoba, Cordoba, Spain; CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Spain.

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http://dx.doi.org/10.1016/j.foodchem.2014.04.047DOI Listing
November 2014

Adipose tissue μ-crystallin is a thyroid hormone-binding protein associated with systemic insulin sensitivity.

J Clin Endocrinol Metab 2014 Nov 24;99(11):E2259-68. Epub 2014 Jul 24.

Department of Diabetes, Endocrinology, and Nutrition, Institut d'Investigació Biomèdica de Girona, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CB06/03/010), and Instituto de Salud Carlos III, 17007 Girona, Spain.

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http://dx.doi.org/10.1210/jc.2014-1327DOI Listing
November 2014

Brain iron overload, insulin resistance, and cognitive performance in obese subjects: a preliminary MRI case-control study.

Diabetes Care 2014 Nov 14;37(11):3076-83. Epub 2014 Aug 14.

Diabetes, Endocrinology and Nutrition Group, Girona Biomedical Research Institute, Dr. Trueta University Hospital, and Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBERobn), Girona, Spain

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http://dx.doi.org/10.2337/dc14-0664DOI Listing
November 2014

Fine-tuned iron availability is essential to achieve optimal adipocyte differentiation and mitochondrial biogenesis.

Diabetologia 2014 Sep 29;57(9):1957-67. Epub 2014 Jun 29.

Department of Diabetes, Endocrinology and Nutrition, Institut d'Investigació Biomèdica de Girona (IdIBGi), Hospital of Girona 'Dr Josep Trueta', Girona, Spain.

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http://dx.doi.org/10.1007/s00125-014-3298-5DOI Listing
September 2014