Jose Luis Molinuevo

Jose Luis Molinuevo

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Jose Luis Molinuevo

Publications by authors named "Jose Luis Molinuevo"

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Associations Between the Subjective Cognitive Decline-Questionnaire's Scores, Gray Matter Volume, and Amyloid-β Levels.

J Alzheimers Dis 2019 Nov 7. Epub 2019 Nov 7.

Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clinic, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-190624DOI Listing
November 2019

Plant-Rich Dietary Patterns, Plant Foods and Nutrients, and Telomere Length.

Adv Nutr 2019 Nov;10(Supplement_4):S296-S303

BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.

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http://dx.doi.org/10.1093/advances/nmz026DOI Listing
November 2019

Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.

Alzheimers Dement 2019 Oct 17. Epub 2019 Oct 17.

Department of Neurodegenerative Diseases & Geropsychiatry/Neurology, University of Bonn Medical Center, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.07.018DOI Listing
October 2019

Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey.

Alzheimers Res Ther 2019 Aug 22;11(1):74. Epub 2019 Aug 22.

Alzheimer Centre, Department of Neurology, VU University Medical Centre, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13195-019-0525-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706888PMC
August 2019

Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects.

Neuroimage Clin 2019 Aug 16;24:101983. Epub 2019 Aug 16.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742967PMC
August 2019

MRI-Based Screening of Preclinical Alzheimer's Disease for Prevention Clinical Trials.

J Alzheimers Dis 2018 ;64(4):1099-1112

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-180299DOI Listing
July 2019

The Rationale Behind the New Alzheimer's Disease Conceptualization: Lessons Learned During the Last Decades.

J Alzheimers Dis 2018 ;62(3):1067-1077

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-170698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869992PMC
May 2019

CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals.

Neuroimage Clin 2019 1;23:101801. Epub 2019 Apr 1.

Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain; Neurology Department, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain; Universitat Pompeu Fabra, Spain; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458453PMC
April 2019

APOE-ε4 risk variant for Alzheimer's disease modifies the association between cognitive performance and cerebral morphology in healthy middle-aged individuals.

Neuroimage Clin 2019 8;23:101818. Epub 2019 Apr 8.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain; Universitat Pompeu Fabra, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463204PMC
April 2019

CSF-ApoER2 fragments as a read-out of reelin signaling: Distinct patterns in sporadic and autosomal-dominant Alzheimer disease.

Clin Chim Acta 2019 Mar 12;490:6-11. Epub 2018 Dec 12.

Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, 03550 Sant Joan d'Alacant, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183064
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http://dx.doi.org/10.1016/j.cca.2018.12.012DOI Listing
March 2019

Mechanisms of functional compensation, delineated by eigenvector centrality mapping, across the pathophysiological continuum of Alzheimer's disease.

Neuroimage Clin 2019 12;22:101777. Epub 2019 Mar 12.

Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434094PMC
March 2019

Perspectives on Communicating Biomarker-Based Assessments of Alzheimer's Disease to Cognitively Healthy Individuals.

J Alzheimers Dis 2018 ;62(2):487-498

Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.

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http://dx.doi.org/10.3233/JAD-170813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836405PMC
February 2019

Neuroimaging Methods for MRI Analysis in CSF Biomarkers Studies.

Methods Mol Biol 2018 ;1750:165-184

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.

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http://dx.doi.org/10.1007/978-1-4939-7704-8_11DOI Listing
February 2019

European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol.

BMJ Open 2019 02 19;8(12):e021017. Epub 2019 Feb 19.

Centre for Dementia Prevention, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1136/bmjopen-2017-021017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318591PMC
February 2019

Executive and Language Subjective Cognitive Decline Complaints Discriminate Preclinical Alzheimer's Disease from Normal Aging.

J Alzheimers Dis 2018 ;61(2):689-703

Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clinic, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-170627DOI Listing
January 2019

Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets.

Neuroimage Clin 2018 16;19:190-201. Epub 2018 Apr 16.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Neurology Department, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050455PMC
January 2019

Frontotemporal Dementia Caused by the P301L Mutation in the MAPT Gene: Clinicopathological Features of 13 Cases from the Same Geographical Origin in Barcelona, Spain.

Dement Geriatr Cogn Disord 2017 22;44(3-4):213-221. Epub 2017 Sep 22.

Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Department, Hospital Clínic-Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1159/000480077DOI Listing
October 2018

The impact of preanalytical variables on measuring cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: A review.

Alzheimers Dement 2018 10 23;14(10):1313-1333. Epub 2018 Jun 23.

Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2018.05.008DOI Listing
October 2018

Cost-Utility of Using Alzheimer's Disease Biomarkers in Cerebrospinal Fluid to Predict Progression from Mild Cognitive Impairment to Dementia.

J Alzheimers Dis 2017 ;60(4):1477-1487

Department of Neurobiology, Care Science and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institute, Huddinge, Sweden.

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http://dx.doi.org/10.3233/JAD-170324DOI Listing
July 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease.

Alzheimers Dement 2018 07 28;14(7):902-912. Epub 2018 Mar 28.

Barcelonabeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Catalonia, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.01.016DOI Listing
July 2018

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.

World J Biol Psychiatry 2018 06 27;19(4):244-328. Epub 2017 Oct 27.

a Department of Psychiatry and Psychotherapy , Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg , Erlangen , Germany.

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http://dx.doi.org/10.1080/15622975.2017.1375556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916324PMC
June 2018

European Prevention of Alzheimer's Dementia Registry: Recruitment and prescreening approach for a longitudinal cohort and prevention trials.

Alzheimers Dement 2018 06 28;14(6):837-842. Epub 2018 Mar 28.

Department of Neurology and Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Centre Limburg, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2018.02.010DOI Listing
June 2018

New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia.

Alzheimers Dement 2018 06 26;14(6):703-706. Epub 2018 May 26.

Editor-in-Chief, Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Rockville, MD, USA.

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http://dx.doi.org/10.1016/j.jalz.2018.05.002DOI Listing
June 2018

A whole-brain computational modeling approach to explain the alterations in resting-state functional connectivity during progression of Alzheimer's disease.

Neuroimage Clin 2017 8;16:343-354. Epub 2017 Aug 8.

Center for Brain and Cognition, Computational Neuroscience Group, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona 08018, Spain.

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http://dx.doi.org/10.1016/j.nicl.2017.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568172PMC
May 2018

Long-term exposure to residential green and blue spaces and anxiety and depression in adults: A cross-sectional study.

Environ Res 2018 04 19;162:231-239. Epub 2018 Jan 19.

ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.envres.2018.01.012DOI Listing
April 2018

The Crus exhibits stronger functional connectivity with executive network nodes than with the default mode network.

Brain 2018 04;141(4):e24

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1093/brain/awy025DOI Listing
April 2018

Tauopathy with Hippocampal 4-Repeat Tau Immunoreactive Spherical Inclusions in a Patient with PSP.

Brain Pathol 2018 03;28(2):284-286

Neurological Tissue Bank of the Biobanc-Hospital Clinic-IDIBAPS, Barcelona, Spain.

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http://dx.doi.org/10.1111/bpa.12506DOI Listing
March 2018

Quantitative Magnetic Resonance Abnormalities in Creutzfeldt-Jakob Disease and Fatal Insomnia.

J Alzheimers Dis 2017 ;55(1):431-443

Neurological Tissue Bank of the Biobanc-Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-160750DOI Listing
February 2018

Cerebrospinal Fluid Aβ42/40 Corresponds Better than Aβ42 to Amyloid PET in Alzheimer's Disease.

J Alzheimers Dis 2017 ;55(2):813-822

The Knight Alzheimer's Disease Research Center, Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.3233/JAD-160722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147502PMC
February 2018

Learning non-linear patch embeddings with neural networks for label fusion.

Med Image Anal 2018 02 2;44:143-155. Epub 2017 Dec 2.

Department of Information and Communication Technologies, Universitat Pompeu Fabra, Tànger 122-140, Barcelona 08018, Spain; ICREA, Pg. Lluis Companys 23, Barcelona 08010 Spain.

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http://dx.doi.org/10.1016/j.media.2017.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896774PMC
February 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 01;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

CSF microRNA Profiling in Alzheimer's Disease: a Screening and Validation Study.

Mol Neurobiol 2017 11 13;54(9):6647-6654. Epub 2016 Oct 13.

Alzheimer's disease and other cognitive disorders unit, Neurology Service, Hospital Clínic i Universitari-, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Villarroel 170, Barcelona, 08036, Spain.

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http://dx.doi.org/10.1007/s12035-016-0106-xDOI Listing
November 2017

Cerebral amyloid angiopathy in Down syndrome and sporadic and autosomal-dominant Alzheimer's disease.

Alzheimers Dement 2017 Nov 29;13(11):1251-1260. Epub 2017 Apr 29.

Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Barcelona Down Medical Center, Fundació Catalana de Síndrome de Down, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, CIBERNED, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660938PMC
November 2017

Plasma miR-34a-5p and miR-545-3p as Early Biomarkers of Alzheimer's Disease: Potential and Limitations.

Mol Neurobiol 2017 09 8;54(7):5550-5562. Epub 2016 Sep 8.

Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, Spain.

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http://dx.doi.org/10.1007/s12035-016-0088-8DOI Listing
September 2017

Alzheimer's disease prevention: from risk factors to early intervention.

Alzheimers Res Ther 2017 Sep 12;9(1):71. Epub 2017 Sep 12.

Barcelonaβeta Brain Research Center-Pasqual Maragall Foundation, C/Wellington, 30, 08005, Barcelona, Spain.

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http://dx.doi.org/10.1186/s13195-017-0297-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596480PMC
September 2017

Effect of long-term exposure to air pollution on anxiety and depression in adults: A cross-sectional study.

Int J Hyg Environ Health 2017 08 3;220(6):1074-1080. Epub 2017 Jul 3.

ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ijheh.2017.06.009DOI Listing
August 2017

White Matter Abnormalities Track Disease Progression in PSEN1 Autosomal Dominant Alzheimer's Disease.

J Alzheimers Dis 2016 ;51(3):827-35

Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-150899DOI Listing
December 2016

Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease.

Alzheimers Dement 2016 12 14;12(12):1259-1272. Epub 2016 Jul 14.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.06.005DOI Listing
December 2016

The ε4 genotype modulates CSF YKL-40 levels and their structural brain correlates in the continuum of Alzheimer's disease but not those of sTREM2.

Alzheimers Dement (Amst) 2017 22;6:50-59. Epub 2016 Dec 22.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.dadm.2016.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266482PMC
December 2016

Altered Blood Gene Expression of Tumor-Related Genes (PRKCB, BECN1, and CDKN2A) in Alzheimer's Disease.

Mol Neurobiol 2016 11 28;53(9):5902-5911. Epub 2015 Oct 28.

Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1007/s12035-015-9483-9DOI Listing
November 2016

Preservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotype.

Neurobiol Aging 2016 10 15;46:169-79. Epub 2016 Jul 15.

Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC, Barcelona, Spain; Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.002DOI Listing
October 2016

Exome sequencing in a consanguineous family clinically diagnosed with early-onset Alzheimer's disease identifies a homozygous CTSF mutation.

Neurobiol Aging 2016 10 4;46:236.e1-6. Epub 2016 Jul 4.

Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166571PMC
October 2016

Cerebrospinal fluid Presenilin-1 increases at asymptomatic stage in genetically determined Alzheimer's disease.

Mol Neurodegener 2016 Sep 29;11(1):66. Epub 2016 Sep 29.

Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, 03550, Av. Ramón y Cajal s/n, Sant Joan d'Alacant, E-03550, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043603PMC
http://dx.doi.org/10.1186/s13024-016-0131-2DOI Listing
September 2016

Modeling practice effects in healthy middle-aged participants of the Alzheimer and Families parent cohort.

Alzheimers Dement (Amst) 2016 30;4:149-158. Epub 2016 Aug 30.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.dadm.2016.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061467PMC
August 2016

Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project.

Lancet Psychiatry 2016 Feb 10;3(2):179-86. Epub 2015 Dec 10.

Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.

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http://dx.doi.org/10.1016/S2215-0366(15)00454-XDOI Listing
February 2016

CSF YKL-40 and pTau181 are related to different cerebral morphometric patterns in early AD.

Neurobiol Aging 2016 Feb 2;38:47-55. Epub 2015 Nov 2.

Clinical and Neuroimaging Departments, Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

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February 2016

Informants' Perception of Subjective Cognitive Decline Helps to Discriminate Preclinical Alzheimer's Disease from Normal Aging.

J Alzheimers Dis 2015 Sep;48 Suppl 1:S87-98

Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clinic, Barcelona, Spain.

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http://dx.doi.org/10.3233/JAD-150117DOI Listing
September 2015