Jose Jalife

Jose Jalife

UNVERIFIED PROFILE

Are you Jose Jalife?   Register this Author

Register author
Jose Jalife

Jose Jalife

Publications by authors named "Jose Jalife"

Are you Jose Jalife?   Register this Author

100Publications

2561Reads

30Profile Views

Mechanisms by Which Ranolazine Terminates Paroxysmal but Not Persistent Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2019 Oct 9;12(10):e005557. Epub 2019 Oct 9.

Center for Arrhythmia Research, Department of Internal Medicine-Cardiology, University of Michigan, Ann Arbor (R.J.R., Y.T., R.P.M., D.F.-R., S.R.E., S.M., O.B., J.J., S.V.P.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.117.005557DOI Listing
October 2019

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources.

J Physiol 2019 Sep 27;597(17):4533-4564. Epub 2019 Jul 27.

Department of Physiology and Membrane Biology, Department of Pharmacology, School of Medicine, University of California, Davis, Davis, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/JP277724DOI Listing
September 2019

Instantaneous Amplitude and Frequency Modulations Detect the Footprint of Rotational Activity and Reveal Stable Driver Regions as Targets for Persistent Atrial Fibrillation Ablation.

Circ Res 2019 Aug 1;125(6):609-627. Epub 2019 Aug 1.

From the Myocardial Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.G.Q., J.M.A.-A., J.J., D.F.-R.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.119.314930DOI Listing
August 2019

Clinical Characteristics and Electrophysiological Mechanisms Underlying Brugada ECG in Patients With Severe Hyperkalemia.

J Am Heart Assoc 2019 Feb;8(3):e010115

1 Department of Cardiology Hospital General Universitario Gregorio Marañón Instituto de Investigación Sanitaria Gregorio Marañón Facultad de Medicina Universidad Complutense Madrid Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.118.010115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405573PMC
February 2019

Mechanisms and Drug Development in Atrial Fibrillation.

Pharmacol Rev 2018 07;70(3):505-525

Department of Cardiology, Arrhythmia Unit, Hospital Universitario Central de Asturias and Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain (D.C.); Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain (D.F.-R., J.J.); Department of Cardiology, Arrhythmia Unit, Hospital Clínico Universitario San Carlos, Madrid, Spain (D.F.-R.); Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain (D.F.-R., J.J.); and Center for Arrhythmia Research, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan (J.J.)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/pr.117.014183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010660PMC
July 2018

Factors affecting basket catheter detection of real and phantom rotors in the atria: A computational study.

PLoS Comput Biol 2018 03 5;14(3):e1006017. Epub 2018 Mar 5.

Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1006017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854439PMC
March 2018

The tornadoes of sudden cardiac arrest.

Authors:
José Jalife

Nature 2018 03;555(7698):597-598

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/d41586-018-01950-1DOI Listing
March 2018

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.

Am J Hum Genet 2018 01 28;102(1):103-115. Epub 2017 Dec 28.

Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777936PMC
January 2018

Eplerenone Reduces Atrial Fibrillation Burden Without Preventing Atrial Electrical Remodeling.

J Am Coll Cardiol 2017 Dec;70(23):2893-2905

Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan; Centro Nacional de Investigaciones Cardiovasculares Carlos III and CIBERCV, Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacc.2017.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726581PMC
December 2017

Triple threat: adiposity, aging, atrial fibrillation.

Aging (Albany NY) 2017 Nov;9(11):2235-2236

The Department of Internal Medicine/Cardiovascular Medicine University of Michigan, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723680PMC
November 2017

Synergistic Research Between the Center of Arrhythmia Research and the Michigan Biology of Cardiovascular Aging at the University of Michigan.

Circ Res 2017 11;121(11):1221-1223

From the Department of Internal Medicine/Cardiovascular Medicine, University of Michigan, Ann Arbor.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.117.311374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726534PMC
November 2017

hiPSC-CM Monolayer Maturation State Determines Drug Responsiveness in High Throughput Pro-Arrhythmia Screen.

Sci Rep 2017 10 23;7(1):13834. Epub 2017 Oct 23.

University of Michigan, Internal Medicine-Cardiology, Center for Arrhythmia Research, Ann Arbor, MI, 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-13590-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653750PMC
October 2017

Propagation of Sinus Waves in the Atrial Architecture: When Laminar Electrical Fluxes Turn Turbulent.

Circ Arrhythm Electrophysiol 2017 09;10(9)

From the Arrhythmia Unit, Instituto de Investigación Sanitaria del Principado de Asturias, Hospital Universitario Central de Asturias, Oviedo, Spain (D.C.); Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC) Carlos III, Madrid, Spain (D.F., J.J.); Hospital Clínico Universitario San Carlos, Madrid, Spain (D.F.-R.); Center for Arrhythmia Research, University of Michigan, Ann Arbor (D.F., J.J.); and CIBERCV, Madrid, Spain (D.F., J.J.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.117.005699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678985PMC
September 2017

Is TGF-β (Transforming Growth Factor-β) an Enabler of Myofibroblast-Cardiomyocyte Cross Talk?

Circ Arrhythm Electrophysiol 2017 05;10(5):e005289

From the Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor (K.K., J.J.); Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain (J.J.); and Centro de Investigación Biomédica en Red, Enfermedades Cardiovasculares, Spain (J.J.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.117.005289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508726PMC
May 2017

Selection of the Best of 2016 in Catheter Ablation.

Rev Esp Cardiol (Engl Ed) 2017 Apr;70(4):302-303

Departamento de Cardiología, Hospital Universitario Clínico San Carlos, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rec.2016.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616107PMC
April 2017

Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias.

Circ Arrhythm Electrophysiol 2016 12;9(12)

From the Department of Pharmacology, University of Michigan Medical School, Ann Arbor (Y.B., C.R.F., L.F.L.-S., C.C., L.L.I.); Center for Arrhythmia Research and Department of Medicine/Cardiovascular Medicine, University of Michigan, Ann Arbor (B.C.W., R.R.-M., J.A., H.H.V., J.J.); Leon H. Charney Division of Cardiology, New York University School of Medicine, NY (X.L., M.D.); Department of Pharmacology and Physiology, University of Rochester Medical Center, NY (D.S.A.); and Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis (Z.W.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.116.003923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161227PMC
December 2016

miR-208b upregulation interferes with calcium handling in HL-1 atrial myocytes: Implications in human chronic atrial fibrillation.

J Mol Cell Cardiol 2016 Oct 18;99:162-173. Epub 2016 Aug 18.

Cardiovascular Development and Repair Department, Spanish National Cardiovascular Research Center (CNIC), Madrid, Spain; Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yjmcc.2016.08.012DOI Listing
October 2016

Dynamics and Molecular Mechanisms of Ventricular Fibrillation in Structurally Normal Hearts.

Authors:
José Jalife

Card Electrophysiol Clin 2016 09 24;8(3):601-12. Epub 2016 Jun 24.

Center for Arrhythmia Research, North Campus Research Complex, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccep.2016.04.009DOI Listing
September 2016

Mutated KCNJ5 activates the acute and chronic regulatory steps in aldosterone production.

J Mol Endocrinol 2016 07 20;57(1):1-11. Epub 2016 Apr 20.

Department of Internal MedicineDivision of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, Michigan, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/JME-15-0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027885PMC
July 2016

Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia.

Circulation 2016 Jun 11;133(24):2348-59. Epub 2016 May 11.

From University of Michigan, Ann Arbor (B.C.W., S.V.P., D.P.-B., M.Z., G.G.-S., R.J.R., S.M., T.J.H., H.H.V., J.J.); Norfolk State University, VA (B.L., M.D.); University of Tennessee Health Science Center, Memphis (E.C.); and Fundación Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain (J.J.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.021936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902321PMC
June 2016

Nav1.5 N-terminal domain binding to α1-syntrophin increases membrane density of human Kir2.1, Kir2.2 and Nav1.5 channels.

Cardiovasc Res 2016 May 19;110(2):279-90. Epub 2016 Jan 19.

Department of Pharmacology, School of Medicine, Universidad Complutense, Madrid 28040, Spain Instituto de Investigación Sanitaria Gregorio Marañón, School of Medicine, Universidad Complutense, Madrid 28040, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cvr/cvw009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836625PMC
May 2016

Atrial Fibrillation Susceptibility in Obesity: An Excess Adiposity and Fibrosis Complicity?

Circ Res 2016 05;118(10):1468-1471

Center for Arrhythmia Research, Department of Internal Medicine-Cardiology, University of Michigan, Ann Arbor, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.116.308686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869997PMC
May 2016

Mechanisms of Atrial Fibrillation: Rotors, Ionic Determinants, and Excitation Frequency.

Heart Fail Clin 2016 Apr;12(2):167-78

Center for Arrhythmia Research, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hfc.2015.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547895PMC
April 2016

Novel Upstream Approaches to Prevent Atrial Fibrillation Perpetuation.

Authors:
José Jalife

Heart Fail Clin 2016 Apr;12(2):309-22

Center for Arrhythmia Research, Cardiovascular Research Center, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hfc.2015.08.024DOI Listing
April 2016

Extracellular Matrix-Mediated Maturation of Human Pluripotent Stem Cell-Derived Cardiac Monolayer Structure and Electrophysiological Function.

Circ Arrhythm Electrophysiol 2016 Apr;9(4):e003638

From the Center for Arrhythmia Research, Department of Internal Medicine, Cardiovascular Research Center, University of Michigan, Ann Arbor, MI (T.J.H., A.M.D.R., K.C., D.P.-B., B.C.W., G.G.-S., Q.L., J.F., J.A., S.M., J.J.); Department of Medicine, University of California San Diego, La Jolla, CA (M.K.); Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH (H.M.); Shanxi Medical University, Zhejiang, China (Q.L.); and University of Valencia, Valencia, Spain (M.Z., A.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.113.003638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833010PMC
April 2016

Spectral analysis-based risk score enables early prediction of mortality and cerebral performance in patients undergoing therapeutic hypothermia for ventricular fibrillation and comatose status.

Int J Cardiol 2015 14;186:250-8. Epub 2015 Mar 14.

Bio-ITACA Grupo de Bioingeniería, Instituto de Aplicaciones Avanzadas, Dpto Ingeniería Electrónica, Universitat Politècnica de Valencia, Spain; Grupo Electrofisiología y Bioingeniería, Microcluster en Protección Cardiovascular, Dpto de Medicina, Fundación INCLIVA Hospital Clínico, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2015.03.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568426PMC
February 2016

STRUCTURAL AND FUNCTIONAL BASES OF CARDIAC FIBRILLATION. DIFFERENCES AND SIMILARITIES BETWEEN ATRIA AND VENTRICLES.

JACC Clin Electrophysiol 2016 Feb;2(1):1-3

Fundación Centro Nacional de Investigaciones Cardiovasculares, Carlos III (CNIC)., Myocardial Pathophysiology Area, Madrid, Spain; Center for Arrhythmia Research, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, EEUU.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2015.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815272PMC
February 2016

Mechanistic Approaches to Detect, Target, and Ablate the Drivers of Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2016 Jan;9(1):e002481

From the Advanced Development in Arrhythmia Mechanisms and Therapy Laboratory, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain (J.G.Q., J.J., D.F.R.); Arrhythmia Unit, Cardiovascular Institute, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain (J.G.Q., J.P.V., N.P.C, D.F.R.); and Center for Arrhythmia Research, Department of Internal Medicine-Cardiology, University of Michigan, Ann Arbor (S.V.P., O.B., J.J.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.115.002481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547888PMC
January 2016

The elusive rotor electrogram footprint.

Authors:
José Jalife

Europace 2015 Dec 20;17(12):1743-4. Epub 2015 Nov 20.

Center for Arrhythmia Research, University of Michigan, 2800 Plymouth Rd, Ann Arbor, MI 48109, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euv370DOI Listing
December 2015

Ventricular Tachycardia and Early Fibrillation in Patients With Brugada Syndrome and Ischemic Cardiomyopathy Show Predictable Frequency-Phase Properties on the Precordial ECG Consistent With the Respective Arrhythmogenic Substrate.

Circ Arrhythm Electrophysiol 2015 Oct 7;8(5):1133-43. Epub 2015 Aug 7.

From the Arrhythmia Unit, Hospital Universitario Central de Asturias, Oviedo, Spain (D.C., J.R.); Center for Arrhythmia Research, University of Michigan, Ann Arbor (J.J., O.B.); Arrhythmia Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain (F.A., P.Á., Á.A.); Centro de Investigación e Innovación en Bioingeniería, Ci2B, Universitat Politècnica de Valencia, Valencia, Spain (J.S., L.M., A.F.); Arrhythmia Unit, Hospital Río Hortega de Valladolid and Universitario de Burgos, Valladolid-Burgos, Spain (B.H., J.G.-F.); Universitat de Valencia, Valencia, Spain (R.S.); and Department of Statistics, Hospital Universitario Central de Asturias, Oviedo, Spain (P.M.-C.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.114.002717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608487PMC
October 2015

Letter by Jalife et al Regarding Article, "Quantitative Analysis of Localized Sources Identified by Focal Impulse and Rotor Modulation Mapping in Atrial Fibrillation".

Circ Arrhythm Electrophysiol 2015 Oct;8(5):1296-8

Center for Arrhythmia Research, Departments of Internal Medicine and Biomedical Engineering University of Michigan, Ann Arbor, MI.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.115.003324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479569PMC
October 2015

Atrial remodeling, fibrosis, and atrial fibrillation.

Trends Cardiovasc Med 2015 Aug 31;25(6):475-84. Epub 2014 Dec 31.

Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcm.2014.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658790PMC
August 2015

Protein assemblies of sodium and inward rectifier potassium channels control cardiac excitability and arrhythmogenesis.

Am J Physiol Heart Circ Physiol 2015 Jun 10;308(12):H1463-73. Epub 2015 Apr 10.

Department of Internal Medicine and Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan; and Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00176.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469872PMC
June 2015

Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death.

Circ Res 2015 Jun;116(12):1971-88

From the Department of Clinical Research, University of Bern, Bern, Switzerland (H.A., J.-S.R.); Center for Arrhythmia Research, Department of Internal Medicine, University of Michigan, Ann Arbor (J.J.); and Area of Myocardial Pathophysiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (J.J.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.116.305017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471480PMC
June 2015

Role of extracellular histones in the cardiomyopathy of sepsis.

FASEB J 2015 May 13;29(5):2185-93. Epub 2015 Feb 13.

*Department of Pathology and Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Orthopaedic Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital of Ulm, Ulm, Germany; Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA; and Center for Thrombosis and Hemostasis and Department of Hematology, Oncology and Pneumology, University Medical Center, Mainz, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.14-268730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415013PMC
May 2015

Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function.

Proc Natl Acad Sci U S A 2015 Mar 16;112(13):E1669-77. Epub 2015 Mar 16.

Center for Arrhythmia Research, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1419795112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386375PMC
March 2015

A device for rapid and quantitative measurement of cardiac myocyte contractility.

Rev Sci Instrum 2015 Mar;86(3):034302

Center for Arrhythmia Research, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1063/1.4915500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376763PMC
March 2015

[Basic mechanisms of the new antiarrhythmic drugs in atrial fibrillation].

Arch Cardiol Mex 2012 Apr-Jun;82(2):139-52

Unidad de Arritmias y Electrofisiología Cardiaca Robotizada. Departamento de Cardiología. Hospital Universitario La Paz. Madrid, España. Centro para Investigación de Arritmias. Departamento de Medicina Interna, Medicina cardiovascular. Universidad de Michigan. E.U.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576579PMC
January 2015

Spectral analysis of electrograms in a substrate modified by radiofrequency ablation reveals similarities between organized and disorganized atrial rhythms.

Heart Rhythm 2014 Dec 7;11(12):2306-9. Epub 2014 Oct 7.

Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2014.10.008DOI Listing
December 2014

Mechanisms of atrial fibrillation: rotors, ionic determinants, and excitation frequency.

Cardiol Clin 2014 Nov 23;32(4):495-506. Epub 2014 Oct 23.

Center for Arrhythmia Research, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccl.2014.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254447PMC
November 2014

Novel upstream approaches to prevent atrial fibrillation perpetuation.

Authors:
José Jalife

Cardiol Clin 2014 Nov 22;32(4):637-50. Epub 2014 Aug 22.

Center for Arrhythmia Research, Cardiovascular Research Center, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccl.2014.07.004DOI Listing
November 2014

CrossTalk proposal: Rotors have been demonstrated to drive human atrial fibrillation.

J Physiol 2014 Aug;592(15):3163-6

Center for Arrhythmia Research and Department of Internal Medicine/Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2014.271031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146362PMC
August 2014

Rebuttal from Sanjiv M. Narayan and José Jalife.

J Physiol 2014 Aug;592(15):3171

Center for Arrhythmia Research and Department of Medicine/Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2014.275396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146364PMC
August 2014

Dominant frequency increase rate predicts transition from paroxysmal to long-term persistent atrial fibrillation.

Circulation 2014 Apr 24;129(14):1472-82. Epub 2014 Jan 24.

Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI (R.P.M., K.K., E.H., R.J.R., B.C.W., D.F.-R., S.R.E., Y.T., D.P.-B., M.Z., R.P.O., H.M., G.G.-S., U.M.R.A., S.V.P., O.B., J.J.); Department of Surgery, University of Rochester, Rochester, NY (M.F.S.); and Department of Engineering, Norfolk State University, Norfolk, VA (S.B., M.D.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.113.004742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981906PMC
April 2014

Mechanisms of persistent atrial fibrillation.

Authors:
José Jalife

Curr Opin Cardiol 2014 Jan;29(1):20-7

Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HCO.0000000000000027DOI Listing
January 2014

Myosin light chain 2-based selection of human iPSC-derived early ventricular cardiac myocytes.

Stem Cell Res 2013 Nov 18;11(3):1335-47. Epub 2013 Sep 18.

Department of Internal Medicine, Cardiovascular Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48108, USA; Université Pierre et Marie Curie, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scr.2013.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148042PMC
November 2013

Modulated parasystole: still relevant after all these years!

Authors:
José Jalife

Heart Rhythm 2013 Oct 24;10(10):1441-3. Epub 2013 Jun 24.

Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2013.06.018DOI Listing
October 2013

Genetically engineered excitable cardiac myofibroblasts coupled to cardiomyocytes rescue normal propagation and reduce arrhythmia complexity in heterocellular monolayers.

PLoS One 2013 5;8(2):e55400. Epub 2013 Feb 5.

Center for Arrhythmia Research, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055400PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564921PMC
August 2013

Neuroanatomy of the murine cardiac conduction system: a combined stereomicroscopic and fluorescence immunohistochemical study.

Auton Neurosci 2013 Jun 9;176(1-2):32-47. Epub 2013 Feb 9.

Institute of Anatomy, Faculty of Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15660702130000
Publisher Site
http://dx.doi.org/10.1016/j.autneu.2013.01.006DOI Listing
June 2013

Introduction to the series on Computational Approaches to Cardiac Arrhythmias: Translation Into Diagnostics and Therapy.

Authors:
José Jalife

Circ Res 2013 Mar;112(5):831-3

Center for Arrhythmia Research, University of Michigan, NCRC, 2800 Plymouth Rd, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.113.300936DOI Listing
March 2013

Rotors and the dynamics of cardiac fibrillation.

Circ Res 2013 Mar;112(5):849-62

Center for Arrhythmia Research, University of Michigan, NCRC, 2800 Plymouth Rd, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.111.30015
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.111.300158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650644PMC
March 2013

Mechanoelectric feedback in the ischemic myocardium: an interplay that modulates susceptibility to fibrillation.

Rev Esp Cardiol (Engl Ed) 2013 Mar 11;66(3):168-70. Epub 2013 Jan 11.

Center for Arrhythmia Research, University of Michigan, Ann Arbor, Michigan, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.rec.2012.09.017DOI Listing
March 2013

Heterogeneity of ryanodine receptor dysfunction in a mouse model of catecholaminergic polymorphic ventricular tachycardia.

Circ Res 2013 Jan 14;112(2):298-308. Epub 2012 Nov 14.

Center for Arrhythmia Research, Cardiovascular Division, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.112.274803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549355PMC
January 2013

Translational research in atrial fibrillation: a quest for mechanistically based diagnosis and therapy.

Circ Arrhythm Electrophysiol 2012 Dec 27;5(6):1207-15. Epub 2012 Sep 27.

Hospital General Universitario Gregorio Marañón, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.111.970335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535065PMC
December 2012

Spatial gradients in action potential duration created by regional magnetofection of hERG are a substrate for wavebreak and turbulent propagation in cardiomyocyte monolayers.

J Physiol 2012 Dec 22;590(24):6363-79. Epub 2012 Oct 22.

Center for Arrhythmia Research, Department of InternalMedicine, University of Michigan, Ann Arbor, MI 48108, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2012.238758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533198PMC
December 2012

Iatrogenic atrioventricular reentrant tachycardia following Bjork/Fontan palliation of tricuspid atresia: Electro-anatomic mapping, ablation, review and possible mechanism.

J Cardiol Cases 2012 Sep 25;6(3):e66-e69. Epub 2012 Apr 25.

Michigan Congenital Heart Center, University of Michigan Health System, Ann Arbor, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jccase.2012.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269261PMC
September 2012

Biological pacemakers: the oscillatory road ahead.

Heart Rhythm 2012 Aug 10;9(8):1319-20. Epub 2012 May 10.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2012.05.010DOI Listing
August 2012

Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia.

Proc Natl Acad Sci U S A 2012 Jul 16;109(31):E2134-43. Epub 2012 Apr 16.

Departments of Internal Medicine, Molecular and Integrative Physiology, and Pharmacology, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48108, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1109370109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412015PMC
July 2012

Postrepolarization refractoriness in acute ischemia and after antiarrhythmic drug administration.

Heart Rhythm 2012 May 16;9(5):e13-4; author reply e14. Epub 2012 Mar 16.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2012.03.018DOI Listing
May 2012