Jose Hermida

Jose Hermida

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Jose Hermida

Jose Hermida

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Role of age and comorbidities in mortality of patients with infective endocarditis.

Authors:
Carlos Armiñanzas Concepción Fariñas-Alvarez Jesús Zarauza Patricia Muñoz Víctor González Ramallo Manuel Martínez Sellés José Mª Miró Meda Juan Manuel Pericás Miguel Ángel Goenaga Guillermo Ojeda Burgos Regino Rodríguez Álvarez Laura Castelo Corral Juan Gálvez-Acebal Francisco Javier Martínez Marcos Maria Carmen Fariñas Fernando Fernández Sánchez Mariam Noureddine Gabriel Rosas Javier de la Torre Lima José Aramendi Elena Bereciartua María José Blanco Roberto Blanco María Victoria Boado Marta Campaña Lázaro Alejandro Crespo Josune Goikoetxea José Ramón Iruretagoyena Josu Irurzun Zuazabal Leire López-Soria Miguel Montejo Javier Nieto David Rodrigo David Rodríguez Regino Rodríguez Yolanda Vitoria Roberto Voces Mª Victoria García López Radka Ivanova Georgieva Guillermo Ojeda Isabel Rodríguez Bailón Josefa Ruiz Morales Ana María Cuende Tomás Echeverría Ana Fuerte Eduardo Gaminde Miguel Ángel Goenaga Pedro Idígoras José Antonio Iribarren Alberto Izaguirre Yarza Xabier Kortajarena Urkola Carlos Reviejo Rafael Carrasco Vicente Climent Patricio Llamas Esperanza Merino Joaquín Plazas Sergio Reus Nemesio Álvarez José María Bravo-Ferrer Laura Castelo José Cuenca Pedro Llinares Enrique Miguez Rey María Rodríguez Mayo Efrén Sánchez Dolores Sousa Regueiro Francisco Javier Martínez Mª Del Mar Alonso Beatriz Castro Dácil García Rosado Mª Del Carmen Durán Mª Antonia Miguel Gómez Juan Lacalzada Ibrahim Nassar Antonio Plata Ciezar José Mª Reguera Iglesias Víctor Asensi Álvarez Carlos Costas Jesús de la Hera Jonnathan Fernández Suárez Lisardo Iglesias Fraile Víctor León Arguero José López Menéndez Pilar Mencia Bajo Carlos Morales Alfonso Moreno Torrico Carmen Palomo Begoña Paya Martínez Ángeles Rodríguez Esteban Raquel Rodríguez García Mauricio Telenti Asensio Manuel Almela Juan Ambrosioni Manuel Azqueta Mercè Brunet Marta Bodro Ramón Cartañá Carlos Falces Guillermina Fita David Fuster Cristina García de la Mària Marta Hernández-Meneses Jaume Llopis Pérez Francesc Marco José M Miró Asunción Moreno David Nicolás Salvador Ninot Eduardo Quintana Carlos Paré Daniel Pereda Juan M Pericás José L Pomar José Ramírez Irene Rovira Elena Sandoval Marta Sitges Dolors Soy Adrián Téllez José M Tolosana Bárbara Vidal Jordi Vila Iván Adán Javier Bermejo Emilio Bouza Daniel Celemín Gregorio Cuerpo Caballero Antonia Delgado Montero Ana Fernández Cruz Ana García Mansilla Mª Eugenia García Leoni Víctor González Ramallo Martha Kestler Hernández Amaia Mari Hualde Mercedes Marín Manuel Martínez-Sellés Mª Cruz Menárguez Patricia Muñoz Cristina Rincón Hugo Rodríguez-Abella Marta Rodríguez-Créixems Blanca Pinilla Ángel Pinto Maricela Valerio Pilar Vázquez Eduardo Verde Moreno Isabel Antorrena Belén Loeches Alejandro Martín Quirós Mar Moreno Ulises Ramírez Verónica Rial Bastón María Romero Araceli Saldaña Jesús Agüero Balbín Cristina Amado Carlos Armiñanzas Castillo Ana Arnaiz García Manuel Cobo Belaustegui María Carmen Fariñas Concepción Fariñas-Álvarez Rubén Gómez Izquierdo Iván García Claudia González-Rico Manuel Gutiérrez-Cuadra José Gutiérrez Díez Marcos Pajarón José Antonio Parra Aurelio Sarralde Ramón Teira Jesús Zarauza Fernando Domínguez Pablo García Pavía Jesús González Beatriz Orden Antonio Ramos Tomasa Centella José Manuel Hermida José Luis Moya Pilar Martín-Dávila Enrique Navas Enrique Oliva Alejandro Del Río Soledad Ruiz Carmen Hidalgo Tenorio Manuel Almendro Delia Omar Araji José Miguel Barquero Román Calvo Jambrina Marina de Cueto Juan Gálvez Acebal Irene Méndez Isabel Morales Luis Eduardo López-Cortés Arístides de Alarcón Emilio García Juan Luis Haro José Antonio Lepe Francisco López Rafael Luque Luis Javier Alonso Pedro Azcárate José Manuel Azcona Gutiérrez José Ramón Blanco Lara García-Álvarez José Antonio Oteo Mercedes Sanz Natividad de Benito Mercé Gurguí Cristina Pacho Roser Pericas Guillem Pons M Álvarez A L Fernández Amparo Martínez A Prieto Benito Regueiro E Tijeira Marino Vega Andrés Canut Blasco José Cordo Mollar Juan Carlos Gainzarain Arana Oscar García Uriarte Alejandro Martín López Zuriñe Ortiz de Zárate José Antonio Urturi Matos Gloria García Domínguez Antonio Sánchez-Porto José Mª Arribas Leal Elisa García Vázquez Alicia Hernández Torres Ana Blázquez Gonzalo de la Morena Valenzuela Ángel Alonso Javier Aramburu Felicitas Elena Calvo Anai Moreno Rodríguez Paola Tarabini-Castellani Eva Heredero Gálvez Carolina Maicas Bellido José Largo Pau Mª Antonia Sepúlveda Pilar Toledano Sierra Sadaf Zafar Iqbal-Mirza Eva Cascales Alcolea Pilar Egea Serrano José Joaquín Hernández Roca Ivan Keituqwa Yañez Ana Peláez Ballesta Víctor Soriano Eduardo Moreno Escobar Alejandro Peña Monje Valme Sánchez Cabrera David Vinuesa García María Arrizabalaga Asenjo Carmen Cifuentes Luna Juana Núñez Morcillo Mª Cruz Pérez Seco Aroa Villoslada Gelabert Carmen Aured Guallar Nuria Fernández Abad Pilar García Mangas Marta Matamala Adell Mª Pilar Palacián Ruiz Juan Carlos Porres Begoña Alcaraz Vidal Nazaret Cobos Trigueros María Jesús Del Amor Espín José Antonio Giner Caro Roberto Jiménez Sánchez Amaya Jimeno Almazán Alejandro Ortín Freire Monserrat Viqueira González Pere Pericás Ramis Mª Ángels Ribas Blanco Enrique Ruiz de Gopegui Bordes Laura Vidal Bonet Mª Carmen Bellón Munera Elena Escribano Garaizabal Antonia Tercero Martínez Juan Carlos Segura Luque

Eur J Intern Med 2019 Jun 21;64:63-71. Epub 2019 Mar 21.

Complejo Hospitalario Universitario de Albacete Albacete, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S09536205193008
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http://dx.doi.org/10.1016/j.ejim.2019.03.006DOI Listing
June 2019

Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.

Thromb Haemost 2017 08 27;117(9):1722-1729. Epub 2017 Jul 27.

José Hermida, MD,PhD, University of Navarra, Center for Applied Medical Research (CIMA), Laboratory of Thrombosis and Haemostasis, Pío XII 55, Pamplona 31008, Spain, Tel.: +34948194700×3027, Fax: +34948194716, E-mail:

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH17-02-0108
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http://dx.doi.org/10.1160/TH17-02-0108DOI Listing
August 2017

Management of a tracheoesophageal fistula in a patient with AIDS.

Asian Cardiovasc Thorac Ann 2017 Mar 1;25(3):226-228. Epub 2017 Jan 1.

2 Department of Infectious Disease, University Hospital Ramón y Cajal, Madrid, Spain.

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http://dx.doi.org/10.1177/0218492317696374DOI Listing
March 2017

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth.

J Hematol Oncol 2017 01 19;10(1):23. Epub 2017 Jan 19.

Adhesion and Metastasis Laboratory, Program Solid Tumors and Biomarkers, Center for Applied Medical Research (CIMA), University of Navarra, 31008, Pamplona, Spain.

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http://dx.doi.org/10.1186/s13045-017-0399-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248526PMC
January 2017

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

Cardiovasc Res 2016 06 14;110(3):309-18. Epub 2016 Mar 14.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Center for Applied Medical Research (CIMA), IdiSNA, Navarra's Health Research Institute, University of Navarra, Pío XII, 55, Pamplona, Spain

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http://dx.doi.org/10.1093/cvr/cvw049DOI Listing
June 2016

Short Leukocyte Telomere Length Is Associated With Cardioembolic Stroke Risk in Patients With Atrial Fibrillation.

Stroke 2016 Mar 19;47(3):863-5. Epub 2016 Jan 19.

From the Cardiovascular Sciences Program, Center for Applied Medical Research (CIMA), Navarra's Health Research Institute (IdiSNA), University of Navarra, Pamplona, Spain (M.A., E.M., J.H.); Department of Haematology, IBSAL-Hospital Universitario de Salamanca, Salamanca, Spain (J.R.G.-P.); Department of Preventive Medicine and Public Health, School of Medicine, University of Navarra, IdiSNA, Pamplona, Spain (E.T.); and Hematology Service, University Clinic of Navarra, IdiSNA, Pamplona, Spain (R.L.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011837DOI Listing
March 2016

Progressive multifocal leukoencephalopathy mimicking milliary CNS tuberculosis.

J Neurovirol 2015 Dec 5;21(6):691-3. Epub 2015 Aug 5.

Department of Radiology, Hospital Ramón y Cajal, Madrid, Spain.

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http://link.springer.com/10.1007/s13365-015-0367-6
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http://dx.doi.org/10.1007/s13365-015-0367-6DOI Listing
December 2015

Factors influencing the use of thromboprophylaxis in cancer outpatients in clinical practice: A prospective study.

Thromb Res 2015 Dec 9;136(6):1145-8. Epub 2015 Oct 9.

Hematology Service, University Clinic of Navarra, Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.10.015DOI Listing
December 2015

Protein C system defects inflicted by the malaria parasite protein PfEMP1 can be overcome by a soluble EPCR variant.

Thromb Haemost 2015 Nov 9;114(5):1038-48. Epub 2015 Jul 9.

Jens E. V. Petersen, Centre for Medical Parasitology, Dept. of International Health, Immunology & Microbiology, University of Copenhagen and Dept. of Infectious Diseases, Rigshospitalet, 1014 Copenhagen, Denmark, Tel.: +45 35327549, Fax: +45 35327851, E-mail:

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http://dx.doi.org/10.1160/TH15-01-0018DOI Listing
November 2015

[Gastrointestinal lesions and characteristics of acute gastrointestinal bleeding in acenocoumarol-treated patients].

Gastroenterol Hepatol 2014 Jun-Jul;37(6):334-41. Epub 2014 Feb 28.

Laboratorio de Trombosis y Hemostasia, Área de Ciencias Cardiovasculares, CIMA de la Universidad de Navarra, Pamplona, España.

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http://dx.doi.org/10.1016/j.gastrohep.2013.12.008DOI Listing
September 2015

Activated protein C β-glycoform promotes enhanced noncanonical PAR1 proteolysis and superior resistance to ischemic injury.

Blood 2015 Aug 17;126(7):915-9. Epub 2015 Jun 17.

Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, United Kingdom; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Crumlin, Dublin, United Kingdom;

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http://dx.doi.org/10.1182/blood-2015-03-632877DOI Listing
August 2015

Laparoscopic limited liver resection decreases morbidity irrespective of the hepatic segment resected.

HPB (Oxford) 2014 Apr 22;16(4):320-6. Epub 2013 Aug 22.

Department of General and Abdominal Surgery, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1111/hpb.12147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967883PMC
April 2014

Neutropenia during therapy with peginterferon and ribavirin in HIV-infected subjects with chronic hepatitis C and the risk of infections.

Clin Infect Dis 2013 Aug 10;57(3):458-64. Epub 2013 Apr 10.

Department of Infectious Diseases, Instituto de Investigacion Sanitaria del Hospital Ramon y Cajal (IRICYS), Hospital Universitario Ramon y Cajal, Madrid, Spain.

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http://dx.doi.org/10.1093/cid/cit221DOI Listing
August 2013

High incidence of venous thromboembolism despite electronic alerts for thromboprophylaxis in hospitalised cancer patients.

Thromb Haemost 2013 Jul 16;110(1):184-90. Epub 2013 May 16.

Hematology Service, University Clinic of Navarra, Av. Pío XII, 36, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1160/TH13-02-0131DOI Listing
July 2013

Atrial fibrillation in pigs induces left atrial endocardial transcriptional remodelling.

Thromb Haemost 2012 Oct 26;108(4):742-9. Epub 2012 Jul 26.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1160/TH12-05-0285DOI Listing
October 2012

Is EPCR a multi-ligand receptor? Pros and cons.

Thromb Haemost 2012 May 8;107(5):815-26. Epub 2012 Feb 8.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1160/TH11-11-0766DOI Listing
May 2012

sPLA2-V inhibits EPCR anticoagulant and antiapoptotic properties by accommodating lysophosphatidylcholine or PAF in the hydrophobic groove.

Blood 2012 Mar 13;119(12):2914-21. Epub 2011 Dec 13.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1182/blood-2011-05-353409DOI Listing
March 2012

Usefulness of high-sensitivity C-reactive protein to predict mortality in patients with atrial fibrillation (from the Atherosclerosis Risk In Communities [ARIC] Study).

Am J Cardiol 2012 Jan 29;109(1):95-9. Epub 2011 Sep 29.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://linkinghub.elsevier.com/retrieve/pii/S000291491102554
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http://dx.doi.org/10.1016/j.amjcard.2011.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062871PMC
January 2012

The endothelial cell protein C receptor: its role in thrombosis.

Thromb Res 2011 Nov 7;128(5):410-6. Epub 2011 Sep 7.

Hemostasis and Thrombosis Unit, Research Center, La Fe University Hospital, Valencia, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S00493848110042
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http://dx.doi.org/10.1016/j.thromres.2011.08.001DOI Listing
November 2011

Limited ability to activate protein C confers left atrial endocardium a thrombogenic phenotype: a role in cardioembolic stroke?

Stroke 2011 Sep 23;42(9):2622-4. Epub 2011 Jun 23.

Division of Cardiovascular Sciences, Centre for Applied Medical Research, University of Navarra, Avenida Pío XII, 55, 31008 Pamplona, Spain.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.111.614420
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http://dx.doi.org/10.1161/STROKEAHA.111.614420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178262PMC
September 2011

VEGF₁₂₁b and VEGF₁₆₅b are weakly angiogenic isoforms of VEGF-A.

Mol Cancer 2010 Dec 31;9:320. Epub 2010 Dec 31.

Laboratory of Novel Therapeutic Targets, Division of Oncology, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-9-320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022671PMC
December 2010

Blocking endothelial protein C receptor (EPCR) accelerates thrombus development in vivo.

Thromb Haemost 2010 Jun 29;103(6):1239-44. Epub 2010 Mar 29.

Division of Cardiovascular Sciences, Centre for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1160/TH09-11-0750DOI Listing
June 2010

The endothelial cells downregulate the generation of factor VIIa through EPCR binding.

Br J Haematol 2010 Apr 18;149(1):111-7. Epub 2010 Jan 18.

Centre for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1111/j.1365-2141.2009.08060.xDOI Listing
April 2010

Recombinant expression of biologically active murine soluble EPCR.

Protein Expr Purif 2009 Apr 13;64(2):194-7. Epub 2008 Nov 13.

Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Centre for Applied Medical Research, University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1016/j.pep.2008.11.002DOI Listing
April 2009

The influence of polymorphisms of VKORC1 and CYP2C9 on major gastrointestinal bleeding risk in anticoagulated patients.

Br J Haematol 2008 Dec 15;143(5):727-33. Epub 2008 Oct 15.

Haematology Department and the Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Applied Medical Research Centre and Clinica Universitaria/School of Medicine, University of Navarra, Pamplona, Navarra, Spain.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07414.xDOI Listing
December 2008

[Contributions of the science and food technology to the improvement of health].

An R Acad Nac Med (Madr) 2007 ;124(4):755-70

Real Academia de Medicina de Cantabria.

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October 2008

The functional properties of a truncated form of endothelial cell protein C receptor generated by alternative splicing.

Haematologica 2008 Jun 28;93(6):878-84. Epub 2008 Apr 28.

Haematology Department and the Division of Cardiovascular Sciences, Laboratory of Thrombosis and Haemostasis, Clínica Universitaria/School of Medicine, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.3324/haematol.12376DOI Listing
June 2008

Identification of peptide inhibitors of transforming growth factor beta 1 using a phage-displayed peptide library.

Cytokine 2007 Aug 4;39(2):106-15. Epub 2007 Sep 4.

Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Avda. Pío XII, 55-31008-Pamplona, Spain.

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http://dx.doi.org/10.1016/j.cyto.2007.06.004DOI Listing
August 2007

The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients.

Br J Haematol 2006 Apr;133(2):183-7

Laboratory of Thrombosis and Haemostasis, Haematology Department and Division of Cardiovascular Sciences, Centre for Applied Medical Research, Clínica Universitaria/School of Medicine, University of Navarre, C/Pio XII 55, 3rd floor, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1111/j.1365-2141.2006.06007.xDOI Listing
April 2006

Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation.

FEBS J 2005 Jan;272(1):97-108

Department of Haematology, Division of Investigative Science, Hammersmith Campus, Imperial College London, UK.

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http://dx.doi.org/10.1111/j.1432-1033.2004.04401.xDOI Listing
January 2005

Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death.

Blood 2004 Sep 18;104(5):1369-74. Epub 2004 May 18.

Haematology Department, Clínica Universitaria, University of Navarra, Avenida Pío XII 36, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1182/blood-2004-03-0793DOI Listing
September 2004

Tumor necrosis factor-alpha inhibition reduces CXCL-8 levels but fails to prevent fibrin generation and does not improve outcome in a rabbit model of endotoxic shock.

J Lab Clin Med 2003 Apr;141(4):257-64

Hemostasis and Thrombosis Research Unit, Hematology Service, University Clinic, School of Medicine, University of Navarra, Avenida Pío XII 36, 31008-Pamplona, Spain.

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http://dx.doi.org/10.1067/mlc.2003.32DOI Listing
April 2003

Regulation by nitric oxide of endotoxin-induced tissue factor and plasminogen activator inhibitor-1 in endothelial cells.

Thromb Haemost 2002 Dec;88(6):1060-5

Haematosis and Thrombosis Research Unit, School of Medicine, University of Navarra, Pamplona, Spain.

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December 2002

Interleukin (IL)-8 and growth related oncogene-alpha in severe endotoxemia and the effects of a tumor necrosis factor-alpha/IL-1beta inhibitor on these chemokines.

Exp Mol Pathol 2002 Dec;73(3):220-9

Hemostasis and Thrombosis Research Unit, School of Medicine, University Clinic, University of Navarra, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1006/exmp.2002.2467DOI Listing
December 2002

Differential effects of 2C9*3 and 2C9*2 variants of cytochrome P-450 CYP2C9 on sensitivity to acenocoumarol.

Blood 2002 Jun;99(11):4237-9

Hemostasis and Thrombosis Research Unit, School of Medicine, University of Navarra, Pamplona, Spain.

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http://dx.doi.org/10.1182/blood.v99.11.4237DOI Listing
June 2002