Jose Alcami

Jose Alcami

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Jose Alcami

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Association of a single nucleotide polymorphism in ubxn6 gene with long term non progression phenotype in hiv-positive individuals.

Clin Microbiol Infect 2019 May 31. Epub 2019 May 31.

AIDS Immunopathology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km. 2, 28220 Majadahonda, Madrid, Spain; Hospital Clínic- Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cmi.2019.05.015DOI Listing
May 2019

A small-molecule inhibitor of HIV-1 Rev function detected by a diversity screen based on RRE-Rev interference.

Biochem Pharmacol 2018 10 31;156:68-77. Epub 2018 Jul 31.

Facultad de Medicina, Universidad Católica de Valencia, C/Quevedo 2, 46001 Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.07.040DOI Listing
October 2018

Current situation of HIV research in Spain.

Enferm Infecc Microbiol Clin 2018 09;36 Suppl 1:26-30

Unidad VIH, Hospital Universitari Germans Trias i Pujol, Fundación Lluita contra la SIDA, Badalona, Barcelona, España.

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http://dx.doi.org/10.1016/S0213-005X(18)30243-XDOI Listing
September 2018

Converging roads: the latest science from the 2017 IAS HIV Cure and Cancer Forum.

J Virus Erad 2017 Oct 1;3(4):236-241. Epub 2017 Oct 1.

International and Scientific Relations, ANRS, 101 rue de Tolbiac, 75013Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632552PMC
October 2017

5-Hydroxytyrosol inhibits HIV-1 replication in primary cells of the lower and upper female reproductive tract.

Antiviral Res 2017 06 7;142:16-20. Epub 2017 Mar 7.

AIDS Immunopathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milano, Italy; Vita-Salute San Raffaele University, School of Medicine, Via Olgettina 58, 20132, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2017.03.003DOI Listing
June 2017

Potential role of tyrosine kinase inhibitors during primary HIV-1 infection.

Expert Rev Anti Infect Ther 2017 05 30;15(5):421-423. Epub 2017 Mar 30.

a Infectious Diseases Service, Hospital Clínic , University of Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/14787210.2017.1308823DOI Listing
May 2017

Tyrosine kinase inhibitors: potential use and safety considerations in HIV-1 infection.

Expert Opin Drug Saf 2017 May 26;16(5):547-559. Epub 2017 Apr 26.

a AIDS Immunopathology Unit , National Center of Microbiology, Instituto de Salud Carlos III , Madrid , Spain.

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http://dx.doi.org/10.1080/14740338.2017.1313224DOI Listing
May 2017

The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1.

Sci Rep 2017 05 24;7(1):2385. Epub 2017 May 24.

Department of Infectious Diseases, Hospital Ramón y Cajal, Alcalá de Henares University, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.

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http://dx.doi.org/10.1038/s41598-017-02634-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443841PMC
May 2017

Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways.

Molecules 2017 Feb 19;22(2). Epub 2017 Feb 19.

CIFLORPAN, Center for Pharmacognostic Research on Panamanian Flora, College of Pharmacy, University of Panama, P.O. Box 0824-00172 Panama, Panama.

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http://dx.doi.org/10.3390/molecules22020321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155902PMC
February 2017

Genetic and phenotypic analyses of sequential vpu alleles from HIV-infected IFN-treated patients.

Virology 2017 01 15;500:247-258. Epub 2016 Nov 15.

INSERM, U941, Paris F-75010, France; Univ Paris Diderot, Sorbonne Paris Cité, F-75475 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2016.10.028DOI Listing
January 2017

Hydroxytyrosol: a new class of microbicide displaying broad anti-HIV-1 activity.

AIDS 2016 11;30(18):2767-2776

aAIDS Immunopathology Department, National Centre of Microbiology, Instituto de Salud Carlos III bPharmacology Department, Pharmacy Faculty, Universidad Complutense de Madrid cSeprox Biotech, Madrid, Spain.

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http://dx.doi.org/10.1097/QAD.0000000000001283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106087PMC
November 2016

Guidelines for cloning, expression, purification and functional characterization of primary HIV-1 envelope glycoproteins.

J Virol Methods 2016 10 20;236:184-195. Epub 2016 Jul 20.

INSERM U1108, Institut Pasteur, 75015 Paris, France; Viral Pathogenesis Unit, Department of Virology, Institut Pasteur, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jviromet.2016.07.019DOI Listing
October 2016

Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing.

PLoS One 2015 13;10(10):e0139812. Epub 2015 Oct 13.

Department of Molecular Biology, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), PTS, Granada, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139812PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604205PMC
June 2016

Rate and predictors of progression in elite and viremic HIV-1 controllers.

AIDS 2016 05;30(8):1209-20

aHospital Clinic-Fundació Clinic, HIVACAT, Universidad de Barcelona, Barcelona bLaboratory of Immunovirology, Biomedicine Institute of Seville, Infectious Disease Unit, Virgen del Rocio University Hospital, University of Seville, Seville cIIS-Fundación Jiménez Diaz, UAM, Madrid dHospital Universitario rey Juan Carlos, Móstoles eCentro Nacional de Microbiología ISCIII fAIDS Immunopathology Laboratory, ISCIII, Madrid gHospital la Fe, Valencia hCentro Sanitario Sandoval, Madrid iHospital Trias i Pujol de Can Ruti, Badalona jHospital Donostia, San Sebastian, Spain. *Members of the EC and Immune Pathogenesis Working Group of the Spanish AIDS Research Network are listed in the Acknowledgements.

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http://dx.doi.org/10.1097/QAD.0000000000001050DOI Listing
May 2016

Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.

Biochem Pharmacol 2016 May 17;107:14-28. Epub 2016 Feb 17.

Facultad de Medicina, Universidad Católica de Valencia, C/Quevedo 2, 46001 Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2016.02.007DOI Listing
May 2016

Analysis of Non-AIDS-Defining Events in HIV Controllers.

Clin Infect Dis 2016 05 1;62(10):1304-1309. Epub 2016 Mar 1.

Laboratory of Immunovirology, Clinic Unit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville, Institute of Biomedicine of Seville (IBiS), Virgen del Rocío University Hospital.

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http://dx.doi.org/10.1093/cid/ciw120DOI Listing
May 2016

Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells.

Biochem Pharmacol 2016 Apr 4;106:30-45. Epub 2016 Feb 4.

AIDS Immunopathology Unit, National Center of Microbiology, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2016.02.002DOI Listing
April 2016

Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.

Biochem Pharmacol 2016 May 17;107:14-28. Epub 2016 Feb 17.

Facultad de Medicina, Universidad Católica de Valencia, C/Quevedo 2, 46001 Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2016.02.007DOI Listing
May 2016

PKCθ and HIV-1 Transcriptional Regulator Tat Co-exist at the LTR Promoter in CD4(+) T Cells.

Front Immunol 2016 29;7:69. Epub 2016 Feb 29.

AIDS Immunopathology Unit, National Center of Microbiology, Instituto de Salud Carlos III , Madrid , Spain.

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http://dx.doi.org/10.3389/fimmu.2016.00069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770193PMC
March 2016

Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells.

J Virol 2015 Aug 27;89(16):8162-81. Epub 2015 May 27.

Centre d'Études d'Agents Pathogènes et Biotechnologies pour la Santé (CPBS), CNRS UMR5236, Montpellier, France ENS de Lyon, Lyon, France

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http://dx.doi.org/10.1128/JVI.00469-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524266PMC
August 2015

Isolation, Structural Modification, and HIV Inhibition of Pentacyclic Lupane-Type Triterpenoids from Cassine xylocarpa and Maytenus cuzcoina.

J Nat Prod 2015 May 30;78(5):1045-55. Epub 2015 Apr 30.

†Instituto Universitario de Bio-Orgánica "Antonio González", Universidad de La Laguna, Avenida Astrofísico Francisco Sánchez 2, 38206 La Laguna, Tenerife, Spain.

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http://dx.doi.org/10.1021/np501025rDOI Listing
May 2015

Current situation of the pharmacogenetics of immune recovery in treated HIV-infected patients.

Pharmacogenomics 2014 Apr;15(5):569-72

Infectious Diseases & HIV/AIDS Unit, Department of Internal Medicine, Hospital Universitari de Tarragona Joan XXIII, IISPV, Universitat Rovira i Virgili, Tarragona, Spain.

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http://dx.doi.org/10.2217/pgs.14.1DOI Listing
April 2014

Determination of HIV tropism and its use in the clinical practice.

Expert Rev Anti Infect Ther 2013 Dec 6;11(12):1291-302. Epub 2013 Nov 6.

AIDS Immunopathogenesis Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Crtra. Majadahonda Pozuelo Km2, 28220, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1586/14787210.2013.852469DOI Listing
December 2013

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

Angew Chem Int Ed Engl 2013 Dec 8;52(50):13405-9. Epub 2013 Nov 8.

Universidad Católica de Valencia, C/Quevedo 2, 46001 Valencia (Spain).

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http://dx.doi.org/10.1002/anie.201306665DOI Listing
December 2013

Immune activation promotes evolutionary conservation of T-cell epitopes in HIV-1.

PLoS Biol 2013 2;11(4):e1001523. Epub 2013 Apr 2.

Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, València, Spain.

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http://dx.doi.org/10.1371/journal.pbio.1001523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614509PMC
October 2013

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines.

Proc Natl Acad Sci U S A 2013 Jun 21;110(23):9475-80. Epub 2013 May 21.

Institut National de la Santé et de la Recherche Médicale Unit 1108, Viral Pathogenesis Unit, Department of Virology, 75015 Paris, France.

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http://dx.doi.org/10.1073/pnas.1222205110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677469PMC
June 2013

Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine.

PLoS One 2012 7;7(11):e48848. Epub 2012 Nov 7.

Institut dInvestigations Biomèdiques August Pi i Sunyer (IDIBAPS)-AIDS Research Group, Hospital Clinic, Catalonian Center for HIV Vaccines (HIVACAT) and University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048848PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492255PMC
May 2013

3-Phenylcoumarins as inhibitors of HIV-1 replication.

Molecules 2012 Aug 2;17(8):9245-57. Epub 2012 Aug 2.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Salamanca, CIETUS-IBSAL, 37007 Salamanca, Spain.

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http://dx.doi.org/10.3390/molecules17089245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268528PMC
August 2012

Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy.

Retrovirology 2012 Aug 13;9:68. Epub 2012 Aug 13.

Centro de Biología Molecular "Severo Ochoa", Consejo Superior de Investigaciones Científicas & Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1186/1742-4690-9-68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468358PMC
August 2012

Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

Eur J Med Chem 2012 Jun 28;52:295-303. Epub 2012 Mar 28.

Instituto Universitario de Bio-Orgánica Antonio González and Departamento de Química Orgánica, Universidad de La Laguna, Avenida Astrofísico Francisco Sánchez 2, 38206 La Laguna, Tenerife, Spain.

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http://dx.doi.org/10.1016/j.ejmech.2012.03.035DOI Listing
June 2012

Mechanisms of RNA interference in the HIV-1-host cell interplay.

AIDS Rev 2011 Jul-Sep;13(3):149-60

AIDS Immunopathology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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November 2011

Pharmacogenetics of the lipodystrophy syndrome associated with HIV infection and combination antiretroviral therapy.

Expert Opin Drug Metab Toxicol 2011 Nov;7(11):1365-82

Infectious Diseases and HIV/AIDS Section, Department of Internal Medicine , Hospital Universitari de Tarragona Joan XXIII, IISPV, Universitat Rovira i Virgili, Tarragona, Spain.

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http://dx.doi.org/10.1517/17425255.2011.621941DOI Listing
November 2011

Protein kinase Ctheta is a specific target for inhibition of the HIV type 1 replication in CD4+ T lymphocytes.

J Biol Chem 2011 Aug 13;286(31):27363-77. Epub 2011 Jun 13.

AIDS Immunopathology Unit, National Center of Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1074/jbc.M110.210443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149330PMC
August 2011

[Immunopathogenesis of HIV infection].

Enferm Infecc Microbiol Clin 2011 Mar;29(3):216-26

Unidad de Inmunopatología del Sida, Instituto de Salud Carlos III, Majadahonda, Madrid, España.

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http://dx.doi.org/10.1016/j.eimc.2011.01.006DOI Listing
March 2011

New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection.

J Biol Chem 2011 Feb 30;286(7):4978-90. Epub 2010 Nov 30.

INSERM U819/Unité de Pathogénie Virale, Institut Pasteur, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1074/jbc.M110.168955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037610PMC
February 2011

A therapeutic dendritic cell-based vaccine for HIV-1 infection.

J Infect Dis 2011 Feb 13;203(4):473-8. Epub 2011 Jan 13.

Infectious Diseases Department, Hospital Clinic - HIV Development Program in Catalonia, Institut d'Investigacions Biomédiques August Pi I Sunyer, University of Barcelona, Spain.

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http://dx.doi.org/10.1093/infdis/jiq077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071229PMC
February 2011

A sensitive phenotypic assay for the determination of human immunodeficiency virus type 1 tropism.

J Antimicrob Chemother 2010 Dec 14;65(12):2493-501. Epub 2010 Oct 14.

AIDS Immunopathology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1093/jac/dkq379DOI Listing
December 2010

Broadly neutralizing antibodies and their significance for HIV-1 vaccines.

Curr HIV Res 2010 Dec;8(8):602-12

AIDS Immunopathogenesis Unit, Instituto de Salud Carlos III, Madrid, Spain.

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December 2010

Drastic decrease of transcription activity due to hypermutated long terminal repeat (LTR) region in different HIV-1 subtypes and recombinants.

Antiviral Res 2010 Nov 14;88(2):152-9. Epub 2010 Aug 14.

Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain; National Center for Microbiology, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1016/j.antiviral.2010.08.007DOI Listing
November 2010

Dual role of host cell factors in HIV-1 replication: restriction and enhancement of the viral cycle.

AIDS Rev 2010 Apr-Jun;12(2):103-12

AIDS Immunopathology Unit, National Centre of Microbiology, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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September 2010

Quinoline-based compounds as modulators of HIV transcription through NF-kappaB and Sp1 inhibition.

Antiviral Res 2010 Sep 23;87(3):338-44. Epub 2010 Jun 23.

Centro Nacional de Microbiología, Instituto de Salud Carlos III, Crt. Majadahonda a Pozuelo, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1016/j.antiviral.2010.06.006DOI Listing
September 2010

SDF-1/CXCL12 production by mature dendritic cells inhibits the propagation of X4-tropic HIV-1 isolates at the dendritic cell-T-cell infectious synapse.

J Virol 2010 May 24;84(9):4341-51. Epub 2010 Feb 24.

AIDS Immunopathology Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo Km 2, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1128/JVI.02449-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863755PMC
May 2010

Gold nanoparticles capped with sulfate-ended ligands as anti-HIV agents.

Bioorg Med Chem Lett 2010 May 25;20(9):2718-21. Epub 2010 Mar 25.

Laboratory of GlycoNanotechnology, CIC biomaGUNE/CIBER-BBN, P degrees Miramón 182, San Sebastián E-20009, Spain.

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http://dx.doi.org/10.1016/j.bmcl.2010.03.079DOI Listing
May 2010

HIV-1 latency and eradication of long-term viral reservoirs.

Discov Med 2010 Mar;9(46):185-91

AIDS Immunopathology Unit, Instituto de Salud Carlos III, Madrid, Spain.

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March 2010

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs.

Nat Rev Microbiol 2009 Nov;7(11):798-812

AIDS Immunopathology Unit, National Centre of Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1038/nrmicro2223DOI Listing
November 2009

Multivalent manno-glyconanoparticles inhibit DC-SIGN-mediated HIV-1 trans-infection of human T cells.

Chembiochem 2009 Jul;10(11):1806-9

Laboratory of GlycoNanotechnology, CIC biomaGUNE/CIBER-BBN, P degrees Miramón 182, 20009 San Sebastián, Spain.

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http://dx.doi.org/10.1002/cbic.200900294DOI Listing
July 2009

Molecular phenotype of CXCL12beta 3'UTR G801A polymorphism (rs1801157) associated to HIV-1 disease progression.

Curr HIV Res 2009 Jul;7(4):384-9

Immunogenetics Unit and Human Molecular Pathology Unit, Experimental Biology Department, University of Jaén, Jaén, Spain.

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July 2009

SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro.

Biochem Pharmacol 2009 Mar 3;77(6):965-78. Epub 2008 Dec 3.

Unidad de Inmunopatología del SIDA, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, km. 2, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1016/j.bcp.2008.11.025DOI Listing
March 2009

Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IkappaBalpha and enhances HIV-1 replication in human T lymphocytes.

Retrovirology 2008 Dec 1;5:109. Epub 2008 Dec 1.

AIDS Immunopathology Unit, National Center of Microbiology, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1186/1742-4690-5-109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631510PMC
December 2008

[Infectious diseases research].

Enferm Infecc Microbiol Clin 2008 Dec;26 Suppl 15:40-50

Servicio de Enfermedades Infecciosas, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.

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December 2008

[The HIV replication cycle. Established therapeutic targets and potential targets].

Authors:
José Alcamí

Enferm Infecc Microbiol Clin 2008 Nov;26 Suppl 12:3-10

Unidad de Inmunopatología del Sida, Instituto de Salud Carlos III, Madrid, España.

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November 2008

[Introduction. A brief history of AIDS].

Authors:
José Alcamí

Enferm Infecc Microbiol Clin 2008 Oct;26 Suppl 11:1-4

Unidad de Inmunopatología del Sida, Instituto de Salud Carlos III, Madrid, España.

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October 2008

[Conclusions and perspectives. Maraviroc].

Authors:
José Alcamí

Enferm Infecc Microbiol Clin 2008 Oct;26 Suppl 11:49-54

Unidad de Inmunopatología del Sida, Instituto de Salud Carlos III, Madrid, España.

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October 2008

Guatemalan plants extracts as virucides against HIV-1 infection.

Phytomedicine 2008 Jun 20;15(6-7):520-4. Epub 2008 Feb 20.

Departamento de Inmunopatología del SIDA, Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1016/j.phymed.2007.10.006DOI Listing
June 2008

Application of proteomics technology for analyzing the interactions between host cells and intracellular infectious agents.

Proteomics 2008 Feb;8(4):852-73

Unidad de Inmunopatología del SIDA, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1002/pmic.200700664DOI Listing
February 2008

Basal shuttle of NF-kappaB/I kappaB alpha in resting T lymphocytes regulates HIV-1 LTR dependent expression.

Retrovirology 2007 Aug 8;4:56. Epub 2007 Aug 8.

AIDS Immunopathology Unit, National Center of Microbiology, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1186/1742-4690-4-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1988826PMC
August 2007

Genetic analysis of the long terminal repeat (LTR) promoter region in HIV-1-infected individuals with different rates of disease progression.

Virus Genes 2007 Apr 9;34(2):111-6. Epub 2006 Dec 9.

Department of Infectious Diseases, Hospital Carlos III, C/ Sinesio Delgado, 10, 28029, Madrid, Spain.

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http://dx.doi.org/10.1007/s11262-006-0054-zDOI Listing
April 2007

Anti-HIV activity of stilbene-related heterocyclic compounds.

Bioorg Med Chem Lett 2006 Aug 18;16(15):4075-9. Epub 2006 May 18.

Unidad de Inmunopatalogía, Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220-Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1016/j.bmcl.2006.04.087DOI Listing
August 2006

Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.

Proteomics 2006 Apr;6 Suppl 1:S63-73

AIDS Immunopathology Unit, National Centre of Microbiology, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

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http://dx.doi.org/10.1002/pmic.200500437DOI Listing
April 2006

A safe, effective and affordable HIV vaccine--an urgent global need.

AIDS Rev 2005 Jul-Sep;7(3):131-8

HIV Vaccine Research and Development Group, AIDS Research Unit, Infectious Diseases Department, Hospital Clínic/IDIBAPS, University of Barcelona, Barcelona, Spain.

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December 2005

Current situation in the development of a preventive HIV vaccine.

Enferm Infecc Microbiol Clin 2005 Jul;23 Suppl 2:5-24

Unidad de Inmunopatología del Sida, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, España.

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July 2005