Jos W M van der Meer

Jos W M van der Meer

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Jos W M van der Meer

Publications by authors named "Jos W M van der Meer"

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Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations.

J Allergy Clin Immunol 2020 Apr 9. Epub 2020 Apr 9.

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; CIBSS (Centre for Integrative Biological Signalling Studies), University of Freiburg, Freiburg, Germany; RESIST - Cluster of Excellence 2155 to Hanover Medical School, Satellite Center Freiburg, Freiburg, Germany; Institute of Immunology and Transplantation, Royal Free Hospital and University College London, London, United Kingdom; DZIF (German Center for Infection Research) Satellite Center Freiburg, Freiburg, Germany; Rheumatology and Clinical Immunology, Center for Chronic Immunodeficiency, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.11.051DOI Listing
April 2020

Immune recognition of putative alien microbial structures: Host-pathogen interactions in the age of space travel.

PLoS Pathog 2020 01 30;16(1):e1008153. Epub 2020 Jan 30.

Department of Laboratory Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1008153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991955PMC
January 2020

Mediation analysis shows that a decline in self-efficacy mediates the increase in fatigue severity following an initial positive response to cognitive behavioural therapy in Q fever fatigue syndrome.

J Psychosom Res 2019 12 23;127:109841. Epub 2019 Oct 23.

Department of Medical Psychology, Amsterdam University Medical Centers, Amsterdam Public Health Research Institute, University of Amsterdam, the Netherlands; Expert Centre for Chronic Fatigue, Department of Medical Psychology, Amsterdam University Medical Centers, VU University, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2019.109841DOI Listing
December 2019

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome.

Eur J Immunol 2019 07 9;49(7):1015-1022. Epub 2019 May 9.

Radboud Expertise Center for Q fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.20184801
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http://dx.doi.org/10.1002/eji.201848012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163623PMC
July 2019

Cytokine profiles in patients with Q fever fatigue syndrome.

J Infect 2019 05 23;78(5):349-357. Epub 2019 Jan 23.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands; Department of Internal Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2019.01.006DOI Listing
May 2019

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

J Transl Med 2019 05 14;17(1):157. Epub 2019 May 14.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases 463, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12967-019-1906-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518812PMC
May 2019

Long-term effect of cognitive behavioural therapy and doxycycline treatment for patients with Q fever fatigue syndrome: One-year follow-up of the Qure study.

J Psychosom Res 2019 01 12;116:62-67. Epub 2018 Nov 12.

Expert Center for Chronic Fatigue, Department of Medical Psychology, VU University Medical Centre, Amsterdam, The Netherlands; Department of Medical Psychology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2018.11.007DOI Listing
January 2019

Decontamination of Oral or Digestive Tract for Patients in the Intensive Care Unit.

JAMA 2018 11;320(20):2081-2083

Internal Medicine, Radboudumc, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1001/jama.2018.13764DOI Listing
November 2018

Autoimmunity and B-cell dyscrasia in acute and chronic Q fever: A review of the literature.

Eur J Intern Med 2018 08 19;54:6-12. Epub 2018 Jun 19.

Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands; Radboud Expert Center for Q fever, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2018.06.007DOI Listing
August 2018

Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.

Eur J Clin Microbiol Infect Dis 2018 Jul 26;37(7):1385-1391. Epub 2018 May 26.

Radboud Expertise Center for Q fever, Department of Internal Medicine, Division of Infectious Diseases 463, Radboud University Medical Center, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10096-018-3265-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015096PMC
July 2018

Hair and salivary cortisol in a cohort of women with chronic fatigue syndrome.

Horm Behav 2018 07 29;103:1-6. Epub 2018 May 29.

Department of Psychology, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.yhbeh.2018.05.016DOI Listing
July 2018

Innate immune memory: An evolutionary perspective.

Immunol Rev 2018 05;283(1):21-40

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12647DOI Listing
May 2018

Fatigue Is Associated With Altered Monitoring and Preparation of Physical Effort in Patients With Chronic Fatigue Syndrome.

Biol Psychiatry Cogn Neurosci Neuroimaging 2018 04 12;3(4):392-404. Epub 2018 Feb 12.

Donders Institute for Brain, Cognition, and Behaviour, Radboud University, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1016/j.bpsc.2018.01.015DOI Listing
April 2018

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

Cell 2018 01;172(1-2):135-146.e9

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.025DOI Listing
January 2018

Hypothesis: stimulation of trained immunity as adjunctive immunotherapy in cancer.

J Leukoc Biol 2017 12 10;102(6):1323-1332. Epub 2017 Oct 10.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1189/jlb.5RI0217-064RRDOI Listing
December 2017

Cytokine signatures in chronic fatigue syndrome patients: a Case Control Study and the effect of anakinra treatment.

J Transl Med 2017 12 29;15(1):267. Epub 2017 Dec 29.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12967-017-1371-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747240PMC
December 2017

Cytokine signature in chronic fatigue syndrome.

Proc Natl Acad Sci U S A 2017 11 30;114(45):E9435. Epub 2017 Oct 30.

Radboud University Medical Center, Nijmegen 6500 HB, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1714011114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692594PMC
November 2017

Reply to Raoult.

Clin Infect Dis 2017 09;65(6):1055-1056

Radboud Expertise Center for Q Fever.

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http://dx.doi.org/10.1093/cid/cix470DOI Listing
September 2017

Cytokine Inhibition in Patients With Chronic Fatigue Syndrome.

Ann Intern Med 2017 09;167(6):448

From Radboud University Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.7326/L17-0317DOI Listing
September 2017

Observable phenomena that reveal medical students' clinical reasoning ability during expert assessment of their history taking: a qualitative study.

BMC Med Educ 2017 Aug 29;17(1):147. Epub 2017 Aug 29.

Department of Internal Medicine (463), Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1186/s12909-017-0983-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576321PMC
August 2017

Long-term follow-up after cognitive behaviour therapy for chronic fatigue syndrome.

J Psychosom Res 2017 06 27;97:45-51. Epub 2017 Mar 27.

Expert Center for Chronic Fatigue, Department of Medical Psychology, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, The Netherlands; Academic Medical Center (AMC), University of Amsterdam, Department of Medical Psychology, Amsterdam Public Health research institute, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2017.03.016DOI Listing
June 2017

Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.

Ann Intern Med 2017 Apr 7;166(8):557-564. Epub 2017 Mar 7.

From Radboud University Medical Centre, Nijmegen, and University of Amsterdam, Amsterdam, the Netherlands; and University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.7326/M16-2391DOI Listing
April 2017

Trained Immunity: An Ancient Way of Remembering.

Cell Host Microbe 2017 Mar;21(3):297-300

Department of Internal Medicine, Radboud University Medical Centre, PO box 9101, 6500HB Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.02.003DOI Listing
March 2017

Prefrontal Structure Varies as a Function of Pain Symptoms in Chronic Fatigue Syndrome.

Biol Psychiatry 2017 02 31;81(4):358-365. Epub 2016 Aug 31.

Expert Centre for Chronic Fatigue, Nijmegen; Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2016.07.016DOI Listing
February 2017

NFKB1 regulates human NK cell maturation and effector functions.

Clin Immunol 2017 02 3;175:99-108. Epub 2016 Dec 3.

Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili di Brescia, Italy.

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http://dx.doi.org/10.1016/j.clim.2016.11.012DOI Listing
February 2017

Metabolome of chronic fatigue syndrome.

Proc Natl Acad Sci U S A 2017 02 26;114(6):E910. Epub 2017 Jan 26.

Department of Internal Medicine, Radboud University Medical Centre, 6525 GA, Nijmegen, The Netherlands.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1618447114
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http://dx.doi.org/10.1073/pnas.1618447114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307451PMC
February 2017

Early and late B-cell developmental impairment in nuclear factor kappa B, subunit 1-mutated common variable immunodeficiency disease.

J Allergy Clin Immunol 2017 01 16;139(1):349-352.e1. Epub 2016 Jul 16.

Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Italy.

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http://dx.doi.org/10.1016/j.jaci.2016.05.045DOI Listing
January 2017

Interleukin-1 as a mediator of fatigue in disease: a narrative review.

J Neuroinflammation 2017 01 21;14(1):16. Epub 2017 Jan 21.

Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein Zuid 8, 6500HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12974-017-0796-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251329PMC
January 2017

Innate immunity networks during infection with Borrelia burgdorferi.

Crit Rev Microbiol 2016 25;42(2):233-44. Epub 2014 Jun 25.

a Department of Internal Medicine , and.

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http://dx.doi.org/10.3109/1040841X.2014.929563DOI Listing
December 2016

The challenge of autoinflammatory syndromes: with an emphasis on hyper-IgD syndrome.

Rheumatology (Oxford) 2016 12;55(suppl 2):ii23-ii29

Department of Medicine and Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kew351DOI Listing
December 2016

Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-γ therapy.

J Allergy Clin Immunol 2016 09 7;138(3):895-898. Epub 2016 Apr 7.

Department of Internal Medicine, and RadboudUMC Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.02.025DOI Listing
September 2016

Adaptation and memory in innate immunity.

Semin Immunol 2016 08;28(4):317-8

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.smim.2016.07.002DOI Listing
August 2016

30 years hids-Travels between bedside and bench.

Temperature (Austin) 2015 Jan-Mar;2(1):1-7. Epub 2015 Feb 3.

Radboud University Medical Center ; Nijmegen, The Netherlands.

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http://dx.doi.org/10.1080/23328940.2014.995569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843863PMC
May 2016

Altered interferon-γ response in patients with Q-fever fatigue syndrome.

J Infect 2016 Apr 25;72(4):478-85. Epub 2016 Jan 25.

Department of Internal Medicine, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2016.01.004DOI Listing
April 2016

The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis.

J Interferon Cytokine Res 2016 Apr 27;36(4):267-76. Epub 2016 Jan 27.

1 Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre , Nijmegen, The Netherlands .

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http://dx.doi.org/10.1089/jir.2015.0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827303PMC
April 2016

Inflammasome-independent regulation of IL-1-family cytokines.

Annu Rev Immunol 2015 10;33:49-77. Epub 2014 Dec 10.

Department of Internal Medicine.

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http://dx.doi.org/10.1146/annurev-immunol-032414-112306DOI Listing
December 2015

Long-term in vitro and in vivo effects of γ-irradiated BCG on innate and adaptive immunity.

J Leukoc Biol 2015 Dec 16;98(6):995-1001. Epub 2015 Jun 16.

Departments of *Internal Medicine and Gastroenterology, Radboud University Medical Center, Nijmegen, The Netherlands; Research Center for Vitamins and Vaccines, Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark; and Odense Patient Data Explorative Network, University of Southern Denmark/Odense University Hospital, Copenhagen, Denmark

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http://dx.doi.org/10.1189/jlb.4MA0215-059RDOI Listing
December 2015

Trained immunity: A smart way to enhance innate immune defence.

Mol Immunol 2015 Nov;68(1):40-4

Department of Internal Medicine, Radboud University Medical Centre, PO Box 9101, 6500HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2015.06.019DOI Listing
November 2015

Immune defence against Candida fungal infections.

Nat Rev Immunol 2015 Oct 21;15(10):630-42. Epub 2015 Sep 21.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/nri3897DOI Listing
October 2015

Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial.

Trials 2015 Oct 5;16:439. Epub 2015 Oct 5.

Department of Internal Medicine, Radboud University Medical Center, Post Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13063-015-0971-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595002PMC
October 2015

Immunotherapy with G-CSF in patients with chronic mucocutaneous candidiasis.

Immunol Lett 2015 Sep 18;167(1):54-6. Epub 2015 May 18.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01652478150007
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http://dx.doi.org/10.1016/j.imlet.2015.05.008DOI Listing
September 2015

Haploinsufficiency of the NF-κB1 Subunit p50 in Common Variable Immunodeficiency.

Am J Hum Genet 2015 Sep 13;97(3):389-403. Epub 2015 Aug 13.

Center for Chronic Immunodeficiency, University Medical Center Freiburg and University of Freiburg, Freiburg 79108, Germany; Institute of Immunity and Transplantation, University College London, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564940PMC
September 2015

The long wait for a breakthrough in chronic fatigue syndrome.

BMJ 2015 May 5;350:h2087. Epub 2015 May 5.

Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.

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http://dx.doi.org/10.1136/bmj.h2087DOI Listing
May 2015

Anti-SSA antibodies are present in immunoglobulin preparations.

Transfusion 2015 Apr 13;55(4):832-7. Epub 2014 Nov 13.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://doi.wiley.com/10.1111/trf.12922
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http://dx.doi.org/10.1111/trf.12922DOI Listing
April 2015

The epigenetic memory of monocytes and macrophages as a novel drug target in atherosclerosis.

Clin Ther 2015 Apr 20;37(4):914-23. Epub 2015 Feb 20.

Department of Internal Medicine, Division of Vascular Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clinthera.2015.01.008DOI Listing
April 2015

ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions.

Front Immunol 2015 12;6:54. Epub 2015 Feb 12.

Department of Medicine, Radboud University Medical Center, Nijmegen Institute for Infection, Inflammation and Immunity (N4i) , Nijmegen , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2015.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325933PMC
March 2015

TLR2/TLR4-dependent exaggerated cytokine production in hyperimmunoglobulinaemia D and periodic fever syndrome.

Rheumatology (Oxford) 2015 Feb 29;54(2):363-8. Epub 2014 Aug 29.

Department of Internal Medicine, Radboud University Medical Center and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands. Department of Internal Medicine, Radboud University Medical Center and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Nijmegen, The Netherlands.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keu341DOI Listing
February 2015

Myeloid lineage-restricted somatic mosaicism of NLRP3 mutations in patients with variant Schnitzler syndrome.

J Allergy Clin Immunol 2015 Feb 16;135(2):561-4. Epub 2014 Sep 16.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, The Netherlands; Nijmegen Center for Immunodeficiency and Autoinflammation, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2014.07.050DOI Listing
February 2015

Ebola Virus Disease has Features of Hemophagocytic Lymphohistiocytosis Syndrome.

Front Med (Lausanne) 2015 4;2. Epub 2015 Feb 4.

Department of Internal Medicine, Radboud University Medical Centre , Nijmegen , Netherlands.

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http://journal.frontiersin.org/Article/10.3389/fmed.2015.000
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http://dx.doi.org/10.3389/fmed.2015.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316785PMC
February 2015

Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.

Front Microbiol 2014 7;5:762. Epub 2015 Jan 7.

Department of Medicine, University of Colorado Denver Denver, CO, USA ; Department of Medicine, Radboud University Nijmegen Medical Center Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fmicb.2014.00762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285810PMC
January 2015

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection.

Clin Immunol 2014 Dec 25;155(2):213-9. Epub 2014 Oct 25.

Department of Internal Medicine, Radboud University Medical Centre, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.clim.2014.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084088PMC
December 2014

Inflammatory responses to infection: the Dutch contribution.

Immunol Lett 2014 Dec 18;162(2 Pt B):113-20. Epub 2014 Oct 18.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.imlet.2014.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132409PMC
December 2014

Antimicrobial innovation: combining commitment, creativity and coherence.

Nat Rev Drug Discov 2014 Oct;13(10):709-10

Julius-Maximilians-Universität Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany, Chair of the Biosciences Programme at EASAC and Co-Chair of the InterAcademy Partnership.

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http://dx.doi.org/10.1038/nrd4448DOI Listing
October 2014

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis.

Front Microbiol 2014 23;5:483. Epub 2014 Sep 23.

Department of Internal Medicine, Radboud University Medical Center Nijmegen, Netherlands ; Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Radboud University Medical Center Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fmicb.2014.00483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172055PMC
October 2014

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.

PLoS Pathog 2014 Oct 30;10(10):e1004485. Epub 2014 Oct 30.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1004485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214925PMC
October 2014

Carbon: no silver bullet.

Science 2014 Sep;345(6201):1130

Secretary to the EASAC Energy Programme; Department of Earth Sciences, University of Oxford, Oxford, OX1 3AN UK.

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http://dx.doi.org/10.1126/science.345.6201.1130-aDOI Listing
September 2014

Tryptophan depletion in chronic fatigue syndrome, a pilot cross-over study.

BMC Res Notes 2014 Sep 16;7:650. Epub 2014 Sep 16.

Department of General Internal Medicine, Nijmegen Expert Centre Chronic Fatigue, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/1756-0500-7-650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176591PMC
September 2014

Innate immune memory: towards a better understanding of host defense mechanisms.

Curr Opin Immunol 2014 Aug 12;29:1-7. Epub 2014 Mar 12.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.02.006DOI Listing
August 2014

Immunogenicity of the Q fever skin test.

J Infect 2014 Aug 15;69(2):161-4. Epub 2014 Mar 15.

Department of Internal Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jinf.2014.03.008DOI Listing
August 2014

Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice.

Eur J Immunol 2014 Aug 27;44(8):2405-14. Epub 2014 May 27.

Department of Internal Medicine, Radboud Center for Infectious Disease, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/eji.201343828DOI Listing
August 2014

Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes.

Arterioscler Thromb Vasc Biol 2014 Aug 5;34(8):1731-8. Epub 2014 Jun 5.

From the Department of Internal Medicine, Division of Experimental Medicine (S.B., J.Q., L.A.B.J., J.W.M.v.d.M., M.G.N.), and Division of Vascular Medicine (N.P.R.), and the Department of Pharmacology-Toxicology (N.P.R.), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1161/ATVBAHA.114.303887DOI Listing
August 2014

Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors.

Clin Vaccine Immunol 2014 Apr 12;21(4):534-45. Epub 2014 Feb 12.

Radboud University Medical Center, Department of Internal Medicine, Division of Experimental Internal Medicine, Nijmegen, The Netherlands.

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http://cvi.asm.org/lookup/doi/10.1128/CVI.00688-13
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http://dx.doi.org/10.1128/CVI.00688-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993125PMC
April 2014

Role of Dectin-2 for host defense against systemic infection with Candida glabrata.

Infect Immun 2014 Mar 16;82(3):1064-73. Epub 2013 Dec 16.

Radboud University Medical Center, Department of Internal Medicine, Division of Experimental Internal Medicine, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/IAI.01189-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957982PMC
March 2014

Comment on "Power of rare diseases: found in translation".

Sci Transl Med 2014 Jan;6(219):219le1

Department of Medicine, Radboud University Medical Center, 6500HB Nijmegen, the Netherlands.

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http://dx.doi.org/10.1126/scitranslmed.3007911DOI Listing
January 2014

Limited humoral and cellular responses to Q fever vaccination in older adults with risk factors for chronic Q fever.

J Infect 2013 Dec 22;67(6):565-73. Epub 2013 Aug 22.

Department of Internal Medicine and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), Radboud University Nijmegen Medical Centre, Internal Postal Code 463, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jinf.2013.08.008DOI Listing
December 2013

Trained innate immunity and atherosclerosis.

Curr Opin Lipidol 2013 Dec;24(6):487-92

aDepartment of Internal Medicine, Division of Experimental Medicine, Radboud University Nijmegen Medical Centre bNijmegen Institute for Infection, Inflammation and Immunity (N4i) cDepartment of Internal Medicine, Division of Vascular Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/MOL.0000000000000023DOI Listing
December 2013

Treating inflammation by blocking interleukin-1 in humans.

Semin Immunol 2013 Dec 23;25(6):469-84. Epub 2013 Nov 23.

Department of Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S10445323130008
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http://dx.doi.org/10.1016/j.smim.2013.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953875PMC
December 2013

The infectious disease challenges of our time.

Front Public Health 2013 22;1. Epub 2013 Mar 22.

Department of Internal Medicine, Nijmegen Instutie for Infection Inflammation and Immunity, Radboud University Nijmegen Medical Centre Nijmegen, Netherlands.

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http://journal.frontiersin.org/article/10.3389/fpubh.2013.00
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http://dx.doi.org/10.3389/fpubh.2013.00007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854861PMC
December 2013