Publications by authors named "Jorma Ilonen"

100Publications

Distribution of HLA-DQ risk genotypes for celiac disease in Ethiopian children.

HLA 2020 Oct 22. Epub 2020 Oct 22.

Department of Clinical Sciences, Lund University, Malmo, Sweden.

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http://dx.doi.org/10.1111/tan.14119DOI Listing
October 2020

Association between family history, early growth and the risk of beta cell autoimmunity in children at risk for type 1 diabetes.

Diabetologia 2020 Oct 7. Epub 2020 Oct 7.

Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00125-020-05287-1DOI Listing
October 2020

Extended family history of type 1 diabetes in HLA-predisposed children with and without islet autoantibodies.

Pediatr Diabetes 2020 Sep 17. Epub 2020 Sep 17.

Department of Pediatrics, PEDEGO Research Unit, Medical Research Center, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1111/pedi.13122DOI Listing
September 2020

Dynamics of Islet Autoantibodies During Prospective Follow-Up From Birth to Age 15 Years.

J Clin Endocrinol Metab 2020 Dec;105(12)

Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1210/clinem/dgaa624DOI Listing
December 2020

Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes.

Diabetologia 2020 Nov 3;63(11):2396-2409. Epub 2020 Sep 3.

Department of Clinical Microbiology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1007/s00125-020-05257-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527319PMC
November 2020

Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease.

Environ Res 2020 Sep 30;188:109864. Epub 2020 Jun 30.

School of Science and Technology, Örebro University, Örebro, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2020.109864DOI Listing
September 2020

HLA-DR-DQ haplotypes and specificity of the initial autoantibody in islet specific autoimmunity.

Pediatr Diabetes 2020 Jul 1. Epub 2020 Jul 1.

Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1111/pedi.13073DOI Listing
July 2020

Association of HLA-DR-DQ alleles, haplotypes, and diplotypes with type 1 diabetes in Saudis.

Diabetes Metab Res Rev 2020 May 17:e3345. Epub 2020 May 17.

Department of Immunology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.

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http://dx.doi.org/10.1002/dmrr.3345DOI Listing
May 2020

Early exposure to cats, dogs and farm animals and the risk of childhood asthma and allergy.

Pediatr Allergy Immunol 2020 04 11;31(3):265-272. Epub 2020 Jan 11.

Faculty of Social Sciences/Health Sciences, Tampere University, Tampere, Finland.

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http://dx.doi.org/10.1111/pai.13186DOI Listing
April 2020

Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells.

Eur J Immunol 2020 04 19;50(4):581-588. Epub 2019 Dec 19.

Department of Clinical Microbiology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1002/eji.201948378DOI Listing
April 2020

Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection.

J Neuroinflammation 2019 Nov 21;16(1):232. Epub 2019 Nov 21.

Pediatric Infectious Diseases, University Children's Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1186/s12974-019-1626-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868812PMC
November 2019

The heterogeneous pathogenesis of type 1 diabetes mellitus.

Nat Rev Endocrinol 2019 11 18;15(11):635-650. Epub 2019 Sep 18.

Department of Paediatrics, University of Oulu and Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1038/s41574-019-0254-yDOI Listing
November 2019

Coeliac disease and HLA-conferred susceptibility to autoimmunity are associated with IgE sensitization in young children.

Allergy 2020 03 2;75(3):692-694. Epub 2019 Oct 2.

Children's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1111/all.14055DOI Listing
March 2020

Interleukin-7, T helper 1, and regulatory T-cell activity-related cytokines are increased during the second trimester of healthy pregnancy compared to non-pregnant women.

Am J Reprod Immunol 2019 12 28;82(6):e13188. Epub 2019 Sep 28.

Department of Immunology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1111/aji.13188DOI Listing
December 2019

Circulating metabolites in progression to islet autoimmunity and type 1 diabetes.

Diabetologia 2019 12 23;62(12):2287-2297. Epub 2019 Aug 23.

Turku Bioscience, University of Turku and Åbo Akademi University, Tykistokatu 6, FI-20520, Turku, Finland.

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http://dx.doi.org/10.1007/s00125-019-04980-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861356PMC
December 2019

Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome.

Nat Commun 2019 08 9;10(1):3621. Epub 2019 Aug 9.

Crown Princess Victoria's Children's Hospital, Region Östergötland, Division of Pediatrics, Linköping University, Linköping, SE 58185, Sweden.

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http://dx.doi.org/10.1038/s41467-019-11460-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689114PMC
August 2019

Characteristics of familial type 1 diabetes: effects of the relationship to the affected family member on phenotype and genotype at diagnosis.

Diabetologia 2019 11 25;62(11):2025-2039. Epub 2019 Jul 25.

Children's Hospital, University of Helsinki, P.O. Box 22, (Stenbäckinkatu 11), FI-00014, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00125-019-4952-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805821PMC
November 2019

Characteristics of Slow Progression to Type 1 Diabetes in Children With Increased HLA-Conferred Disease Risk.

J Clin Endocrinol Metab 2019 11;104(11):5585-5594

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2019-01069DOI Listing
November 2019

Circulating CXCR5PD-1 peripheral T helper cells are associated with progression to type 1 diabetes.

Diabetologia 2019 09 3;62(9):1681-1688. Epub 2019 Jul 3.

Department of Clinical Microbiology, Institute of Clinical Medicine, University of Eastern Finland, Yliopistonranta 1 C, FIN-70210, Kuopio, Finland.

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http://dx.doi.org/10.1007/s00125-019-4936-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677711PMC
September 2019

Early childhood infections and the use of antibiotics and antipyretic-analgesics in Finland, Estonia and Russian Karelia.

Acta Paediatr 2019 11 23;108(11):2075-2082. Epub 2019 Jun 23.

Pediatric Research Center, Children's Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1111/apa.14874DOI Listing
November 2019

Rhinoviruses in infancy and risk of immunoglobulin E sensitization.

J Med Virol 2019 08 25;91(8):1470-1478. Epub 2019 Mar 25.

Department of Virology, Faculty of Medical Sciences and Biotechnology, Tampere University, Tampere, Finland.

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http://doi.wiley.com/10.1002/jmv.25455
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http://dx.doi.org/10.1002/jmv.25455DOI Listing
August 2019

Gliptin-associated Bullous Pemphigoid and the Expression of Dipeptidyl Peptidase-4/CD26 in Bullous Pemphigoid.

Acta Derm Venereol 2019 May;99(6):602-609

Department of Pathology, MRC Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.2340/00015555-3166DOI Listing
May 2019

No evidence of the role of early chemical exposure in the development of β-cell autoimmunity.

Environ Sci Pollut Res Int 2019 Jan 13;26(2):1370-1378. Epub 2018 Nov 13.

Scientific Laboratory, Clinicum, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.

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http://link.springer.com/10.1007/s11356-018-3659-6
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http://dx.doi.org/10.1007/s11356-018-3659-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331740PMC
January 2019

Early childhood CMV infection may decelerate the progression to clinical type 1 diabetes.

Pediatr Diabetes 2019 02 19;20(1):73-77. Epub 2018 Nov 19.

Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.

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http://doi.wiley.com/10.1111/pedi.12788
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http://dx.doi.org/10.1111/pedi.12788DOI Listing
February 2019

Enterovirus infection during pregnancy is inversely associated with atopic disease in the offspring.

Clin Exp Allergy 2018 12 16;48(12):1698-1704. Epub 2018 Oct 16.

Department of Virology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1111/cea.13280DOI Listing
December 2018

Effector T Cell Resistance to Suppression and STAT3 Signaling during the Development of Human Type 1 Diabetes.

J Immunol 2018 08 13;201(4):1144-1153. Epub 2018 Jul 13.

Department of Clinical Microbiology, Institute of Clinical Medicine, University of Eastern Finland, 70210 Kuopio, Finland;

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http://dx.doi.org/10.4049/jimmunol.1701199DOI Listing
August 2018

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.

Cell Host Microbe 2018 07;24(1):146-154.e4

The Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091882PMC
July 2018

Sex as a determinant of type 1 diabetes at diagnosis.

Pediatr Diabetes 2018 11 17;19(7):1221-1228. Epub 2018 Jun 17.

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1111/pedi.12697DOI Listing
November 2018

Class II HLA Genotype Association With First-Phase Insulin Response Is Explained by Islet Autoantibodies.

J Clin Endocrinol Metab 2018 08;103(8):2870-2878

Department of Pediatrics, PEDEGO Research Unit, Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1210/jc.2017-02040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097602PMC
August 2018

Celiac Disease by the Age of 13 Years Is Not Associated With Probiotics Administration in Infancy.

J Pediatr Gastroenterol Nutr 2018 06;66(6):937-940

Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki.

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http://dx.doi.org/10.1097/MPG.0000000000001846DOI Listing
June 2018

Exocrine pancreas function decreases during the progression of the beta-cell damaging process in young prediabetic children.

Pediatr Diabetes 2018 05 17;19(3):398-402. Epub 2017 Oct 17.

Department of Virology, School of Medicine, University of Tampere, Tampere, Finland.

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http://doi.wiley.com/10.1111/pedi.12592
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http://dx.doi.org/10.1111/pedi.12592DOI Listing
May 2018

Vitamin D intake during the first 4 years and onset of asthma by age 5: A nested case-control study.

Pediatr Allergy Immunol 2017 Nov 8;28(7):641-648. Epub 2017 Sep 8.

Faculty of Social Sciences/Health, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1111/pai.12773DOI Listing
November 2017

Transglutaminase antibodies and celiac disease in children with type 1 diabetes and in their family members.

Pediatr Diabetes 2018 03 26;19(2):305-313. Epub 2017 Jul 26.

Scientific Laboratory, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://doi.wiley.com/10.1111/pedi.12563
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http://dx.doi.org/10.1111/pedi.12563DOI Listing
March 2018

Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial.

Gastroenterology 2017 10 5;153(4):961-970.e3. Epub 2017 Jul 5.

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Center for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland; Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland; Folkhälsan Research Center, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.06.049DOI Listing
October 2017

Primary islet autoantibody at initial seroconversion and autoantibodies at diagnosis of type 1 diabetes as markers of disease heterogeneity.

Pediatr Diabetes 2018 03 9;19(2):284-292. Epub 2017 Jun 9.

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1111/pedi.12545DOI Listing
March 2018

Ketoacidosis at diagnosis of type 1 diabetes: Effect of prospective studies with newborn genetic screening and follow up of risk children.

Pediatr Diabetes 2018 03 23;19(2):314-319. Epub 2017 May 23.

Department of Pediatrics, MRC Oulu, PEDEGO Research Unit, University of Oulu and Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1111/pedi.12541DOI Listing
March 2018

Fatty acid status in infancy is associated with the risk of type 1 diabetes-associated autoimmunity.

Diabetologia 2017 07 4;60(7):1223-1233. Epub 2017 May 4.

Department of Public Health Solutions, National Institute for Health and Welfare, PO Box 30, FI-00271, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00125-017-4280-9DOI Listing
July 2017

Characterisation of rapid progressors to type 1 diabetes among children with HLA-conferred disease susceptibility.

Diabetologia 2017 07 31;60(7):1284-1293. Epub 2017 Mar 31.

Children's Hospital, University of Helsinki and Helsinki University Hospital, P.O. Box 22, FI-00014, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00125-017-4258-7DOI Listing
July 2017

Eliminating cows' milk, but not wheat, barley or rye, increases the risk of growth deceleration and nutritional inadequacies.

Acta Paediatr 2017 Jul 25;106(7):1142-1149. Epub 2017 Apr 25.

Department of Pediatrics, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1111/apa.13846DOI Listing
July 2017

Human enterovirus and rhinovirus infections are associated with otitis media in a prospective birth cohort study.

J Clin Virol 2016 12 20;85:1-6. Epub 2016 Oct 20.

School of Medicine, University of Tampere, Lääkärinkatu 1, FIN-33520, Tampere, Finland; Fimlab Laboratories, Pirkanmaa Hospital District, Tampere, Finland.

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http://dx.doi.org/10.1016/j.jcv.2016.10.010DOI Listing
December 2016

Exploring the risk factors for differences in the cumulative incidence of coeliac disease in two neighboring countries: the prospective DIABIMMUNE study.

Dig Liver Dis 2016 Nov 6;48(11):1296-1301. Epub 2016 Jul 6.

Department of Immunology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2016.06.029DOI Listing
November 2016

Continuous glucose monitoring and HbA1c in the evaluation of glucose metabolism in children at high risk for type 1 diabetes mellitus.

Diabetes Res Clin Pract 2016 Oct 6;120:89-96. Epub 2016 Aug 6.

Department of Pediatrics, PEDEGO Research Unit, Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1016/j.diabres.2016.07.027DOI Listing
October 2016

Role of humoral beta-cell autoimmunity in type 1 diabetes.

Pediatr Diabetes 2016 07;17 Suppl 22:17-24

Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://doi.wiley.com/10.1111/pedi.12386
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http://dx.doi.org/10.1111/pedi.12386DOI Listing
July 2016

Polymorphism of IL-10 gene promoter region: association with T cell proliferative responses after acellular pertussis vaccination in adults.

Immunogenetics 2016 10 10;68(9):733-41. Epub 2016 Jun 10.

Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1007/s00251-016-0923-0DOI Listing
October 2016

Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population.

J Clin Endocrinol Metab 2016 08 11;101(8):3018-26. Epub 2016 May 11.

Department of Pediatrics (H.H., J.M.), University of Eastern Finland, and Kuopio University Hospital, Kuopio, Finland; Children's Hospital (P.J.M., M.K., T.O.), University of Helsinki, and Helsinki University Hospital, Helsinki, Finland; Immunogenetics Laboratory (J.I.), University of Turku, and Turku University Hospital, Turku, Finland; Department of Pediatrics (P.N.), Mikkeli Central Hospital, Mikkeli, Finland; Department of Pediatrics (R.V.), Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland; Department of Pediatrics (P.K.), Tampere University Hospital, Tampere, Finland; Department of Pediatrics (K.N.-S.), Turku University Hospital, Turku, Finland; Institute of Clinical Medicine (J.V., J.R., A.S., T.K., M.L.), Internal Medicine, University of Eastern Finland, Kuopio, Finland; Institute of Clinical Medicine (M.L.), Internal Medicine, University of Eastern Finland, and Kuopio University Hospital, Kuopio, Finland.

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http://dx.doi.org/10.1210/jc.2015-4296DOI Listing
August 2016

Immunological Reconstitution in Children After Completing Conventional Chemotherapy of Acute Lymphoblastic Leukemia is Marked by Impaired B-cell Compartment.

Pediatr Blood Cancer 2016 09 10;63(9):1653-6. Epub 2016 May 10.

Division of Pediatric Hematology and Oncology, Department of Pediatrics, Turku University Hospital, University of Turku, Turku, Finland.

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http://doi.wiley.com/10.1002/pbc.26047
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http://dx.doi.org/10.1002/pbc.26047DOI Listing
September 2016

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans.

Cell 2016 May 28;165(4):842-53. Epub 2016 Apr 28.

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950857PMC
May 2016

Serum 25-Hydroxyvitamin D Concentrations in Children Progressing to Autoimmunity and Clinical Type 1 Diabetes.

J Clin Endocrinol Metab 2016 Feb 22;101(2):723-9. Epub 2015 Dec 22.

Medicity (M.M., M.Ko., V.S.), Department of Pediatrics (M.M., J.M., M.Ko., J.T.), Immunogenetics Laboratory (J.I.), University of Turku and Turku University Hospital, and Research Center of Applied and Preventive Cardiovascular Medicine (O.S.), and Department of Physiology (J.T.), Institute of Biomedicine, University of Turku, FI-20520 Turku, Finland; Department of Pediatrics (R.V.), Research Unit for Pediatrics, Dermatology, Clinical Genetics, Obstetrics and Gynecology, Medical Research Center Oulu, University of Oulu, FI 90014 Oulu, Finland; Department of Children and Adolescents (R.V.), Oulu University Hospital, FI 90029 Oulu, Finland; Department of Virology (H.H.), School of Medicine, University of Tampere, and Department of Pediatrics (M.Kn.), Tampere University Hospital, FI-33520 Tampere, Finland; Fimlab Laboratories (H.H.), Pirkanmaa Hospital District, FI-33014 Tampere, Finland; Children's Hospital (M.Kn.), University of Helsinki and Helsinki University Hospital, Research Programs Unit (M.Kn.), Diabetes and Obesity, University of Helsinki, and Folkhälsan Research Center (M.Kn.), FI-00290 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2015-3504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880127PMC
February 2016

Reduced β-cell function in early preclinical type 1 diabetes.

Eur J Endocrinol 2016 Mar 30;174(3):251-9. Epub 2015 Nov 30.

Department of PaediatricsUniversity of Turku and Turku University Hospital, Turku, FinlandMediCity LaboratoriesDepartment of Clinical Medicine, University of Turku, Lemminkäisenkatu 3, 20520 Turku, FinlandPEDEGO Research UnitDepartment of Paediatrics, Medical Research Centre Oulu, University of Oulu, Oulu, FinlandDepartment of Children and AdolescentsOulu University Hospital, Oulu, FinlandClinical Research CentreTurku University Hospital, Turku, FinlandDepartment of PaediatricsTampere University Hospital, Tampere, FinlandNovo Nordisk Farma OyCMR Department, Espoo, FinlandDiabetes Outpatient ClinicTampere, FinlandDepartment of PaediatricsTurku University Hospital, Turku, FinlandResearch Centre of Applied and Preventive Cardiovascular MedicineUniversity of Turku, Turku, FinlandImmunogenetics LaboratoryUniversity of Turku, Turku, FinlandDepartment of Clinical MicrobiologyUniversity of Eastern Finland, Kuopio, FinlandChildren's HospitalUniversity of Helsinki and Helsinki University Hospital, Helsinki, FinlandResearch Programs UnitDiabetes and Obesity, University of Helsinki, Helsinki, FinlandFolkhälsan Research CentreUniversity of Helsinki, Helsinki, FinlandDepartment of PhysiologyInstitute of Biomedicine, University of Turku, Turku, Finland Department of PaediatricsUniversity of Turku and Turku University Hospital, Turku, FinlandMediCity LaboratoriesDepartment of Clinical Medicine, University of Turku, Lemminkäisenkatu 3, 20520 Turku, FinlandPEDEGO Research UnitDepartment of Paediatrics, Medical Research Centre Oulu, University of Oulu, Oulu, FinlandDepartment of Children and AdolescentsOulu University Hospital, Oulu, FinlandClinical Research CentreTurku University Hospital, Turku, FinlandDepartment of PaediatricsTampere University Hospital, Tampere, FinlandNovo Nordisk Farma OyCMR Department, Espoo, FinlandDiabetes Outpatient ClinicTampere, FinlandDepartment of PaediatricsTurku University Hospital, Turku, FinlandResearch Centre of Applied and Preventive Cardiovascu

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http://dx.doi.org/10.1530/EJE-15-0674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712442PMC
March 2016

Positivity for Zinc Transporter 8 Autoantibodies at Diagnosis Is Subsequently Associated With Reduced β-Cell Function and Higher Exogenous Insulin Requirement in Children and Adolescents With Type 1 Diabetes.

Diabetes Care 2016 Jan 30;39(1):118-21. Epub 2015 Oct 30.

Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland Folkhälsan Research Center, University of Helsinki, Helsinki, Finland Tampere Center for Child Health Research, Tampere University Hospital, Tampere, Finland

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http://dx.doi.org/10.2337/dc15-1027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876730PMC
January 2016

The Gene Polymorphism of IL-17 G-152A is Associated with Increased Colonization of Streptococcus pneumoniae in Young Finnish Children.

Pediatr Infect Dis J 2015 Sep;34(9):928-32

From the *Department of Infectious Disease Surveillance and Control, National Institute for Health and Welfare, Turku, Finland; †Department of Pediatrics, Turku University Hospital, Turku, Finland; ‡Turku Institute for Child and Youth Research, §The immunogenetics Laboratory, University of Turku, Finland; ¶Department of Clinical Microbiology, University of Eastern Finland, Kuopio, Finland; and ‖Department of Medical Microbiology and Immunology, University of Turku, Finland.

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http://dx.doi.org/10.1097/INF.0000000000000691DOI Listing
September 2015

Development of gliadin-specific immune responses in children with HLA-associated genetic risk for celiac disease.

Scand J Gastroenterol 2016 10;51(2):168-77. Epub 2015 Jul 10.

a 1 Department of Clinical Microbiology, University of Eastern Finland , Kuopio, Finland.

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http://dx.doi.org/10.3109/00365521.2015.1067328DOI Listing
August 2016

Non-HLA gene effects on the disease process of type 1 diabetes: From HLA susceptibility to overt disease.

J Autoimmun 2015 Jul 12;61:45-53. Epub 2015 Jun 12.

Immunogenetics Laboratory, University of Turku, Turku, Finland; Department of Clinical Microbiology, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1016/j.jaut.2015.05.005DOI Listing
July 2015

OGTT and random plasma glucose in the prediction of type 1 diabetes and time to diagnosis.

Diabetologia 2015 Aug 19;58(8):1787-96. Epub 2015 May 19.

Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University Hospital and University of Oulu, PO Box 5000, FIN-90014, Oulu, Finland,

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http://link.springer.com/10.1007/s00125-015-3621-9
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http://dx.doi.org/10.1007/s00125-015-3621-9DOI Listing
August 2015