Jorma Hinkula

Jorma Hinkula

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Jorma Hinkula

Jorma Hinkula

Publications by authors named "Jorma Hinkula"

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Dissecting multi drug resistance in head and neck cancer cells using multicellular tumor spheroids.

Sci Rep 2019 Dec 27;9(1):20066. Epub 2019 Dec 27.

Department of Clinical and Experimental Medicine (IKE), Linköping University, Linköping, Sweden.

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http://dx.doi.org/10.1038/s41598-019-56273-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934860PMC
December 2019

Detection of rotavirus- and norovirus-specific IgG memory B cells in tonsils.

J Med Virol 2019 02 16;91(2):326-329. Epub 2018 Jul 16.

Division of Molecular Virology, Department of Clinical and Experimental Medicine, University of Linköping, Linköping, Sweden.

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http://dx.doi.org/10.1002/jmv.25247DOI Listing
February 2019

Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth.

Proc Natl Acad Sci U S A 2018 04 2;115(16):E3808-E3816. Epub 2018 Apr 2.

Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden;

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http://dx.doi.org/10.1073/pnas.1722333115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910864PMC
April 2018

Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3.

PLoS One 2014 14;9(8):e104814. Epub 2014 Aug 14.

Dept. of Immunology, University of Oslo and Oslo University Hospital - Rikshospitalet, Oslo, Norway; Centre for Immune Regulation, University of Oslo, Oslo, Norway; KG Jebsen Centre for research on Influenza Vaccines, University of Oslo, Oslo, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133255PMC
March 2016

Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1.

J Immunol 2015 Aug 8;195(4):1698-704. Epub 2015 Jul 8.

Division of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, 58185 Linköping, Sweden; and

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http://dx.doi.org/10.4049/jimmunol.1500618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528080PMC
August 2015

Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3.

J Immunol 2014 Nov 24;193(9):4590-601. Epub 2014 Sep 24.

Division of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden;

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http://dx.doi.org/10.4049/jimmunol.1401781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201991PMC
November 2014

Intranasally administered Endocine formulated 2009 pandemic influenza H1N1 vaccine induces broad specific antibody responses and confers protection in ferrets.

Vaccine 2014 May 30;32(26):3307-15. Epub 2014 Mar 30.

Viroclinics Biosciences B.V., 3029 AK Rotterdam, The Netherlands; Department of Viroscience, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.03.061DOI Listing
May 2014

Endocine™, N3OA and N3OASq; three mucosal adjuvants that enhance the immune response to nasal influenza vaccination.

PLoS One 2013 8;8(8):e70527. Epub 2013 Aug 8.

Division of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070527PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738562PMC
April 2014

Blocking of integrins inhibits HIV-1 infection of human cervical mucosa immune cells with free and complement-opsonized virions.

Eur J Immunol 2013 Sep 25;43(9):2361-72. Epub 2013 Jun 25.

Division of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

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http://dx.doi.org/10.1002/eji.201243257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231223PMC
September 2013

NK cell function and antibodies mediating ADCC in HIV-1-infected viremic and controller patients.

Viral Immunol 2011 Oct 29;24(5):359-68. Epub 2011 Sep 29.

Department of Microbiology, Tumor and Cell Biology and Strategic Research Center IRIS, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1089/vim.2011.0025DOI Listing
October 2011

Assessment of mucosal immunity to HIV-1.

Expert Rev Vaccines 2010 Apr;9(4):381-94

HIV/STI Epidemiology and Control Unit, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerpen, Belgium.

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http://dx.doi.org/10.1586/erv.10.21DOI Listing
April 2010

NK cell activation by KIR-binding antibody 1-7F9 and response to HIV-infected autologous cells in viremic and controller HIV-infected patients.

Clin Immunol 2010 Feb 1;134(2):158-68. Epub 2009 Nov 1.

Department of Microbiology, Tumor and Cell Biology and Strategic Research Center IRIS, Karolinska Institutet, Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S152166160900841
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http://dx.doi.org/10.1016/j.clim.2009.10.001DOI Listing
February 2010

Maternal immune status influences HIV-specific immune responses in pups after DNA prime protein boost using mucosal adjuvant.

Vaccine 2008 Nov 16;26(47):5957-66. Epub 2008 Sep 16.

Swedish Institute for Infectious Disease Control & Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2008.08.060DOI Listing
November 2008

Intranasal immunization of young mice with a multigene HIV-1 vaccine in combination with the N3 adjuvant induces mucosal and systemic immune responses.

Vaccine 2008 Sep 15;26(40):5075-8. Epub 2008 Apr 15.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet and Swedish Institute for Infectious Disease Control, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.066DOI Listing
September 2008

Safety and immunogenicity, after nasal application of HIV-1 DNA gagp37 plasmid vaccine in young mice.

Vaccine 2008 Sep 25;26(40):5101-6. Epub 2008 Apr 25.

Department of Molecular Virology, Linkoping University, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2008.03.098DOI Listing
September 2008

Parenteral administration of RF 8-2/6/7 rotavirus-like particles in a one-dose regimen induce protective immunity in mice.

Vaccine 2008 Aug 25;26(35):4594-601. Epub 2008 Jun 25.

Instituto de Biologia Experimental e Tecnologica and Instituto de Tecnologia Quimica e Biologica, SE-171 76 Oeiras, Portugal.

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http://dx.doi.org/10.1016/j.vaccine.2008.05.089DOI Listing
August 2008

Individuals with selective IgA deficiency resolve rotavirus disease and develop higher antibody titers (IgG, IgG1) than IgA competent individuals.

J Med Virol 2008 Mar;80(3):531-5

Instituto de Biologia Experimental e Tecnologica and Instituto de Tecnologia Quimica e Biologica, Oeiras, Portugal.

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http://doi.wiley.com/10.1002/jmv.21101
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http://dx.doi.org/10.1002/jmv.21101DOI Listing
March 2008

Murine models for HIV vaccination and challenge.

Expert Rev Vaccines 2008 Feb;7(1):117-30

Swedish Institute for Infectious Disease Control and Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1586/14760584.7.1.117DOI Listing
February 2008

The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent.

Virology 2007 Dec 5;369(2):299-308. Epub 2007 Sep 5.

Department of Virology, Haartman Institute, PO Box 21, FIN-000 14 University of Helsinki, Finland.

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http://dx.doi.org/10.1016/j.virol.2007.08.009DOI Listing
December 2007

Candidate HIV-1 gp140DeltaV2, Gag and Tat vaccines protect against experimental HIV-1/MuLV challenge.

Vaccine 2007 Sep 27;25(39-40):6882-90. Epub 2007 Jul 27.

Swedish Institute for Infectious Disease Control, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2007.07.012DOI Listing
September 2007

Clarification of how HIV-1 DNA and protein immunizations may be better used to obtain HIV-1-specific mucosal and systemic immunity.

Authors:
Jorma Hinkula

Expert Rev Vaccines 2007 Apr;6(2):203-12

Department of Molecular Virology, Linkoping University, Linkoping, Sweden.

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http://dx.doi.org/10.1586/14760584.6.2.203DOI Listing
April 2007

Immunization with HIV protease peptides linked to syngeneic erythrocytes.

Infect Agent Cancer 2007 Apr 18;2. Epub 2007 Apr 18.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1186/1750-9378-2-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1857698PMC
April 2007

Efficient expression of recombinant human monoclonal antibodies in Drosophila S2 cells.

J Immunol Methods 2007 Jan 25;318(1-2):37-46. Epub 2006 Sep 25.

Karolinska Institutet, Department of Medicine at Center for Molecular Medicine, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jim.2006.08.017DOI Listing
January 2007

Elimination of HIV-1 infection by treatment with a doxorubicin-conjugated anti-envelope antibody.

AIDS 2006 Oct;20(15):1911-5

Swedish Institute for Infectious Disease Control, Microbiology and Tumor Biology Center, Karolinska Institutet, S-171 82 Solna, Sweden.

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http://dx.doi.org/10.1097/01.aids.0000247111.58961.60DOI Listing
October 2006

Antiretroviral therapy does not induce HIV type 1-specific neutralizing activity against autologous HIV type 1 isolates.

AIDS Res Hum Retroviruses 2006 Sep;22(9):908-11

Swedish Institute for Infectious Disease Control, Department of Virology, 171 82 Solna, Sweden.

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http://www.liebertpub.com/doi/10.1089/aid.2006.22.908
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http://dx.doi.org/10.1089/aid.2006.22.908DOI Listing
September 2006

A novel DNA adjuvant, N3, enhances mucosal and systemic immune responses induced by HIV-1 DNA and peptide immunizations.

Vaccine 2006 May 19;24(21):4494-7. Epub 2005 Aug 19.

Swedish Institute for Infectious Disease Control and Microbiology and Tumorbiology Center, Karolinska Institutet, Department of Virology, SE-171 82 Stockholm, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S0264410X0500810
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http://dx.doi.org/10.1016/j.vaccine.2005.08.015DOI Listing
May 2006

Responses of mice immunized with a DNA vaccine encoding carcinoembryonic antigen (CEA).

Vaccine 2006 May 24;24(21):4572-5. Epub 2005 Aug 24.

Microbiology and Tumor Biology Center, and Swedish Institute for Infectious Disease Control, Karolinska Institutet, Tomtebodavägen 12B, S-171 82 Solna, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2005.08.044DOI Listing
May 2006

Reduced cellular immune responses following immunization with a multi-gene HIV-1 vaccine.

Vaccine 2006 May 18;24(21):4524-6. Epub 2005 Aug 18.

Department of Virology, Swedish Institute for Infectious Disease Control, 17182 Solna, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2005.08.018DOI Listing
May 2006

Immunological cross-reactivity against a drug mutated HIV-1 protease epitope after DNA multi-CTL epitope construct immunization.

Vaccine 2006 May 18;24(21):4527-30. Epub 2005 Aug 18.

Swedish Institute for Infectious Disease Control, Karolinska Institute, 171 82 Solna, Sweden.

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http://dx.doi.org/10.1016/j.vaccine.2005.08.019DOI Listing
May 2006

A nonsense mutation (428G-->A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection.

AIDS 2006 Mar;20(5):685-9

Department of Forensic Genetics, National Board of Forensic Medicine, University Hospital, Linköping, Sweden.

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https://insights.ovid.com/crossref?an=00002030-200603210-000
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http://dx.doi.org/10.1097/01.aids.0000216368.23325.bcDOI Listing
March 2006

Elevated levels of serum perforin in chronic HIV-1 and acute SIV/SHIV infection.

AIDS 2006 Jan;20(1):125-7

Swedish Institute for Infectious Disease Control, SE-171 82 Solna, Sweden.

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http://dx.doi.org/10.1097/01.aids.0000196170.57927.e1DOI Listing
January 2006

Activation of innate immunity, inflammation, and potentiation of DNA vaccination through mammalian expression of the TLR5 agonist flagellin.

J Immunol 2005 Sep;175(6):3882-91

Center for Infectious Medicine, F59, Department of Medicine, Karolinska Institutet, Karolinska University Hospital at Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.175.6.3882DOI Listing
September 2005

Genetic immunization with multiple HIV-1 genes provides protection against HIV-1/MuLV pseudovirus challenge in vivo.

Cells Tissues Organs 2004 ;177(3):169-84

Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1159/000079991DOI Listing
March 2005

Intranasal HIV-1-gp160-DNA/gp41 peptide prime-boost immunization regimen in mice results in long-term HIV-1 neutralizing humoral mucosal and systemic immunity.

J Immunol 2004 Dec;173(11):7078-89

Swedish Institute for Infectious Disease Control and Microbiology and Tumorbiology Center, Department of Virology, Karolinska Institute, Solna, Sweden.

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http://dx.doi.org/10.4049/jimmunol.173.11.7078DOI Listing
December 2004

Cis-cleavage affects hammerhead and hairpin ribozyme steady-state levels differently and has strong impact on trans-targeting efficiency.

Oligonucleotides 2004 ;14(1):11-21

Division of Molecular Neurobiology, Karolinska Institutet, MBB, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1089/154545704322988012DOI Listing
November 2004

Demonstration of neutralizing mucosal IgA response to intranasal HIV-1 env DNA vaccines with or without the V3 glycosylation site.

Scand J Infect Dis 2004 ;36(5):360-4

Department of Clinical Virology, University of Göteborg, Guldhedsgatan IOB, S-41346, Göteborg, Sweden.

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http://dx.doi.org/10.1080/00365540410020208DOI Listing
August 2004

Primary murine cells as a model for HIV-1 infection.

AIDS 2004 Apr;18(7):1067-9

Microbiology and Tumor Biology Center and Department of Virology, Swedish Institute for Infectious Disease Control, Karolinska Institute, 17182 Solna, Sweden.

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http://dx.doi.org/10.1097/00002030-200404300-00016DOI Listing
April 2004

Therapeutic vaccination with MVA-HIV-1 nef elicits Nef-specific T-helper cell responses in chronically HIV-1 infected individuals.

Vaccine 2003 Dec;22(1):21-9

Institute of Molecular Virology, GSF-National Research Centre for Environment and Health, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/s0264-410x(03)00538-3DOI Listing
December 2003

Induction of HIV-1-specific immunity after vaccination with apoptotic HIV-1/murine leukemia virus-infected cells.

J Immunol 2002 Nov;169(10):5771-9

Department of Medicine, Center for Infectious Medicine, Huddinge University Hospital, F82 Karolinska Institutet, S-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.169.10.5771DOI Listing
November 2002

Enhanced immune responses after DNA vaccination with combined envelope genes from different HIV-1 subtypes.

Virology 2002 Oct;302(1):44-57

Department of Virology, Swedish Institute for Infectious Disease Control and Microbiology and Tumor Biology Center, Karolinska Institute, SE-17182, Stockholm, Sweden.

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http://dx.doi.org/10.1006/viro.2002.1547DOI Listing
October 2002