Jorge Melendez-Zajgla

Jorge Melendez-Zajgla

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Jorge Melendez-Zajgla

Jorge Melendez-Zajgla

Publications by authors named "Jorge Melendez-Zajgla"

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69Publications

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Microenvironment-regulated lncRNA-HAL is able to promote stemness in breast cancer cells.

Biochim Biophys Acta Mol Cell Res 2019 Aug 8:118523. Epub 2019 Aug 8.

Epigenetics, Instituto Nacional de Medicina Genomica, Periferico Sur No.4809, Col Arenal Tepepan, Tlalpan, Mexico City 14610, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.118523DOI Listing
August 2019

IKKε regulates the breast cancer stem cell phenotype.

Biochim Biophys Acta Mol Cell Res 2019 Apr 5;1866(4):598-611. Epub 2019 Jan 5.

Functional Genomics Laboratories, Instituto Nacional de Medicina Genomica, Periferico Sur No.4809, Col Arenal Tepepan, Tlalpan, Mexico City 14610, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.01.002DOI Listing
April 2019

The emerging role of lncRNAs in the regulation of cancer stem cells.

Cell Oncol (Dordr) 2018 Dec 14;41(6):585-603. Epub 2018 Sep 14.

Epigenetics, Instituto Nacional de Medicina Genomica, Periferico Sur No.4809, Col Arenal Tepepan, Tlalpan, 14610, Mexico City, Mexico.

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http://dx.doi.org/10.1007/s13402-018-0406-4DOI Listing
December 2018

MT4-MMP Modulates the Expression of miRNAs in Breast Cancer Cells.

Arch Med Res 2018 10 18;49(7):471-478. Epub 2019 Feb 18.

Laboratorio de Genómica Funcional, Instituto Nacional de Medicina Genómica, Ciudad de México, México. Electronic address:

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http://dx.doi.org/10.1016/j.arcmed.2019.02.001DOI Listing
October 2018

New emerging roles of microRNAs in breast cancer.

Breast Cancer Res Treat 2018 Sep 9;171(2):247-259. Epub 2018 Jun 9.

Epigenetics Laboratory, Instituto Nacional de Medicina Genómica, Periferico Sur 4809, Arenal Tepepan, 14610, Mexico, CDMX, Mexico.

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http://dx.doi.org/10.1007/s10549-018-4850-7DOI Listing
September 2018

miRNA expression profile in multicellular breast cancer spheroids.

Biochim Biophys Acta Mol Cell Res 2017 Oct 31;1864(10):1642-1655. Epub 2017 May 31.

Epigenetic Laboratory, Instituto Nacional de Medicina, Genómica, Periférico Sur 4809, Arenal Tepepan, 14610 Ciudad de Mexico, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.05.023DOI Listing
October 2017

Tissue inhibitor of metalloproteinases-4 (TIMP-4) regulates stemness in cervical cancer cells.

Mol Carcinog 2016 12 30;55(12):1952-1961. Epub 2015 Nov 30.

Functional Genomics Laboratory, Basic Research Subdirection, National Institute of Genomic Medicine, Ciudad de México, Mexico.

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http://dx.doi.org/10.1002/mc.22442DOI Listing
December 2016

Is there something else besides the proapoptotic AVPI-segment in the Smac/DIABLO protein?

Bol Med Hosp Infant Mex 2016 Nov - Dec;73(6):365-371. Epub 2016 Nov 30.

Unidad de Investigación en Enfermedades Oncológicas, Hospital Infantil de México Federico Gómez, Mexico City, Mexico; División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.bmhimx.2016.10.004DOI Listing
November 2016

Probenecid Sensitizes Neuroblastoma Cancer Stem Cells to Cisplatin.

Cancer Invest 2016 10;34(3):155-66. Epub 2016 Mar 10.

a Functional Genomics Laboratory , Instituto Nacional de Medicina Genomica , Mexico City 14610 , Mexico.

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http://dx.doi.org/10.3109/07357907.2016.1139717DOI Listing
August 2016

Advances in the knowledge of breast cancer stem cells. A review.

Histol Histopathol 2016 Jun 30;31(6):601-12. Epub 2015 Dec 30.

Functional Genomics Laboratory, National Institute of Genomic Medicine, Col. Arenal Tepepan, Delegación Tlalpan, Mexico City, México.

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http://dx.doi.org/10.14670/HH-11-718DOI Listing
June 2016

Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells.

PLoS One 2015 20;10(8):e0135929. Epub 2015 Aug 20.

Basic Research Subdivision, National Institute of Genomic Medicine, Functional Genomics Laboratory, Periferico Sur 4809, Col. Arenal Tepepan, Del. Tlalpan. Mexico, D.F. C.P.14610, Mexico.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135929PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546159PMC
May 2016

Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding.

Sci Rep 2015 Oct 7;5:14838. Epub 2015 Oct 7.

Functional Cancer Genomics Laboratory, National Institute of Genomic Medicine, Mexico D.F., 14610, Mexico.

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http://dx.doi.org/10.1038/srep14838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595840PMC
October 2015

Particulate matter (PM₁₀) induces metalloprotease activity and invasion in airway epithelial cells.

Toxicol Lett 2015 Sep 3;237(3):167-73. Epub 2015 Jun 3.

Instituto Nacional de Cancerología (INCan), Subdirección de Investigación Básica, San Fernando No. 22, Tlalpan, 14080 México, D.F., Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2015.06.001DOI Listing
September 2015

Induction of c-Jun by air particulate matter (PM₁₀) of Mexico city: Participation of polycyclic aromatic hydrocarbons.

Environ Pollut 2015 Aug 20;203:175-182. Epub 2015 Apr 20.

Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Av. San Fernando No. 22, Col Sección XVI. C.P. 14080. Delegación Tlalpan, México, D.F., Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2015.03.051DOI Listing
August 2015

Ectopic expression of new alternative splice variant of Smac/DIABLO increases mammospheres formation.

Int J Clin Exp Pathol 2014 15;7(9):5515-26. Epub 2014 Aug 15.

Functional Cancer Genomics Laboratory, National Institute of Genomic Medicine Periférico Sur 4809, Col. Arenal Tepepan, Tlalpan 14610, Mexico.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203164PMC
July 2015

Tissue inhibitor of metalloproteases-4 (TIMP-4) modulates adipocyte differentiation in vitro.

Exp Cell Res 2015 Jul 19;335(2):207-15. Epub 2015 May 19.

Basic Research Subdirection, National Institute of Genomic Medicine, Functional Genomics Laboratory, Periferico Sur 4809, Col. Arenal Tepepan, Del. Tlalpan, Mexico D.F. 14610, Mexico. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2015.05.006DOI Listing
July 2015

[Cancer genomes: where do we go from here?].

Gac Med Mex 2014 Nov-Dec;150(6):563-9

Subdirección de Investigación Médica, Instituto Nacional de Medicina Genómica, México, D.F.

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March 2015

Landscape of genomic alterations in cervical carcinomas.

Nature 2014 Feb 25;506(7488):371-5. Epub 2013 Dec 25.

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [4].

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http://dx.doi.org/10.1038/nature12881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161954PMC
February 2014

Bcl-3 regulates UVB-induced apoptosis.

Hum Cell 2013 Jun 14;26(2):47-55. Epub 2013 Mar 14.

National Institute of Cancerology, Av. San Fernando 22 Tlalpan, 14080 Mexico, Mexico.

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http://dx.doi.org/10.1007/s13577-012-0056-1DOI Listing
June 2013

Survivin isoform Delta Ex3 regulates tumor spheroid formation.

Cancer Lett 2012 May 8;318(1):61-7. Epub 2011 Dec 8.

Cancer Functional Genomics Laboratory, National Institute of Genomic Medicine, Periferico Sur 4124, Sexto Piso, Torre Zafiro II, Col. Ex Rancho de Anzaldo, Alvaro Obregon, Mexico City, Mexico.

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http://dx.doi.org/10.1016/j.canlet.2011.12.002DOI Listing
May 2012

Probenecid is a chemosensitizer in cancer cell lines.

Cancer Chemother Pharmacol 2012 Feb 23;69(2):495-504. Epub 2011 Aug 23.

Cancer Functional Genomics Laboratory, National Institute of Genomic Medicine, Periferico Sur 4124, 01900 Mexico City, Mexico.

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http://dx.doi.org/10.1007/s00280-011-1725-6DOI Listing
February 2012

Role of Bcl-3 in solid tumors.

Mol Cancer 2011 Dec 23;10:152. Epub 2011 Dec 23.

Instituto Nacional de Cancerología, Mexico City, Mexico.

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http://dx.doi.org/10.1186/1476-4598-10-152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258214PMC
December 2011

Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs.

Met Based Drugs 2008 ;2008:576104

Laboratorio de Biología Molecular, Subdirección de Investigación Básica, Instituto Nacional de Cancerológica, Avenida San Fernando 22, 14080 Tlalpan, Mexico.

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http://dx.doi.org/10.1155/2008/576104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291150PMC
July 2011

Cancer stem cells.

Rev Invest Clin 2011 Mar-Apr;63(2):179-86

Unidad de Genómica Funcional del Cáncer, Instituto Nacional de Medicina Genómica, Universidad Nacional Autónoma de México, Col. Ex-Rancho de Anzaldo, Mexico.

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July 2011

[The Instituto Nacional de Medicina Genómica. Vocation and challenges].

Rev Invest Clin 2010 Sep-Oct;62(5):391-2

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April 2011

Paradoxial changes in the expression of estrogen receptor alpha in breast cancer multicellular spheroids.

Tissue Cell 2010 Oct;42(5):334-7

Molecular Biology Laboratory, Sub-Direction of Basic Research, National Institute of Cancerology, Av. San Fernando 22, Tlalpan 14080, Mexico City, Mexico.

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http://dx.doi.org/10.1016/j.tice.2010.07.006DOI Listing
October 2010

[Personalized medicine. So close and so far away].

Rev Invest Clin 2009 Nov-Dec;61(6):454-5

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April 2010

Tissue inhibitor of metalloproteinases-4. The road less traveled.

Mol Cancer 2008 Nov 21;7:85. Epub 2008 Nov 21.

Instituto Nacional de Medicina Genomica, Mexico.

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http://dx.doi.org/10.1186/1476-4598-7-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599898PMC
November 2008

Role of Smac/DIABLO in cancer progression.

J Exp Clin Cancer Res 2008 Sep 26;27:48. Epub 2008 Sep 26.

Functional Cancer Genomics Laboratory, National Institute of Genomic Medicine, Periferico Sur 4124, Torre Zafiro II 5to piso, Col, Ex-Rancho de Anzaldo, Alvaro Obregon 01900, Mexico City, México.

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http://dx.doi.org/10.1186/1756-9966-27-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566557PMC
September 2008

[Is cancer a transmittable disease?].

Gac Med Mex 2007 Jul-Aug;143(4):353-4

Laboratorio de Biología Molecular, Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Tlalpan, México, DF, México.

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December 2007

Is digitalis compound-induced cardiotoxicity, mediated through guinea-pig cardiomyocytes apoptosis?

Eur J Pharmacol 2007 Jul 30;566(1-3):34-42. Epub 2007 Mar 30.

Departamento de Farmacologia, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, Col. Seccion XVI, 14080 Mexico, D. F., Mexico.

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http://dx.doi.org/10.1016/j.ejphar.2007.03.033DOI Listing
July 2007

Apoptosis induced by cAMP requires Smac/DIABLO transcriptional upregulation.

Cell Signal 2007 Jun 21;19(6):1212-20. Epub 2007 Jan 21.

Molecular Biology Laboratory, Subdireccion de Investigacion Basica, Instituto Nacional de Cancerologia, Mexico City, Mexico.

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http://dx.doi.org/10.1016/j.cellsig.2007.01.001DOI Listing
June 2007

High Smac/DIABLO expression is associated with early local recurrence of cervical cancer.

BMC Cancer 2006 Oct 26;6:256. Epub 2006 Oct 26.

Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Av, San Fernando # 22, Tlalpan 14080 México City, Mexico.

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http://dx.doi.org/10.1186/1471-2407-6-256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225885PMC
October 2006

NF-kappaB does not influence the induction of apoptosis by Ukrain.

Cancer Biol Ther 2006 Jul 26;5(7):788-93. Epub 2006 Jul 26.

Molecular Biology Laboratory, Subdireccion de Investigacion Basica, Instituto Nacional de Cancerologia, Mexico City, Mexico.

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http://dx.doi.org/10.4161/cbt.5.7.2752DOI Listing
July 2006

External membrane vesicles from Helicobacter pylori induce apoptosis in gastric epithelial cells.

FEMS Microbiol Lett 2006 Jul;260(2):178-85

Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Publica, Cuernavaca, México.

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https://academic.oup.com/femsle/article-lookup/doi/10.1111/j
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http://dx.doi.org/10.1111/j.1574-6968.2006.00305.xDOI Listing
July 2006

Proliferation and apoptosis of HeLa cells induced by in vitro stimulation with digitalis.

Eur J Pharmacol 2006 Mar 28;534(1-3):71-6. Epub 2006 Feb 28.

Departamento de Farmacologia, Instituto Nacional de Cardiología Ignacio Chavez, Juan Badiano No. 1, Col. Seccion XVI, 14080 Mexico, Mexico.

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http://dx.doi.org/10.1016/j.ejphar.2006.01.035DOI Listing
March 2006

Inhibitors of apoptosis proteins in human cervical cancer.

BMC Cancer 2006 Feb 27;6:45. Epub 2006 Feb 27.

Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Mexico City, Mexico.

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http://dx.doi.org/10.1186/1471-2407-6-45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403791PMC
February 2006

Tissue inhibitor of metalloproteinases-4 is expressed in cervical cancer patients.

Anticancer Res 2005 Jan-Feb;25(1B):623-7

Subdirección de Investigación Básica, Instituto Nacional de Cancerología, DF Mexico.

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May 2005

Oxaliplatin activity in head and neck cancer cell lines.

Cancer Chemother Pharmacol 2005 Mar 21;55(3):301-5. Epub 2004 Oct 21.

Laboratorio de Biología Molecular, Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Av. San Fernando # 22. Tlalpan, 14000, Mexico, DF, Mexico.

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http://dx.doi.org/10.1007/s00280-004-0847-5DOI Listing
March 2005

SMAC is expressed de novo in a subset of cervical cancer tumors.

BMC Cancer 2004 Nov 23;4:84. Epub 2004 Nov 23.

Subdirección de Investigación Básica. Instituto Nacional de Cancerología, México, DF MEXICO.

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http://dx.doi.org/10.1186/1471-2407-4-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC535940PMC
November 2004

Tissue inhibitor of metalloproteinases-2 growth-stimulatory activity is mediated by nuclear factor-kappa B in A549 lung epithelial cells.

Int J Biochem Cell Biol 2004 Aug;36(8):1655-63

Laboratorio de Biologia Molecular Subdirección de Investigación Básica, Instituto Nacional de Cancerología (INCan), Av. San Fernando 22, Tlalpan, 14080 México City, DF, Mexico.

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http://dx.doi.org/10.1016/j.biocel.2004.02.004DOI Listing
August 2004

[Caspases: apoptosis inducing molecules].

Gac Med Mex 2003 Sep-Oct;139(5):493-9

Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Apartado Postal 70228, C. P. 04510, México, D.F.

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January 2004

Cytogenetic analysis of the mononuclear cell component of giant cell tumors of bone.

Cancer Genet Cytogenet 2003 Oct;146(2):170-2

Laboratorio Cultivo de Tejidos, Instituto Nacional de Pediatria, Mexico City, Mexico.

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http://dx.doi.org/10.1016/s0165-4608(03)00153-5DOI Listing
October 2003

[Mechanism of cellular toxicity induced by digitalis compounds. Study with ouabain].

Arch Cardiol Mex 2002 Jan-Mar;72 Suppl 1:S171-6

Departamento de Farmacología, Instituto Nacional de Cardiología Ignacio Chávez, INCICH, Juan Badiano No. 1, Col. Sección XVI, Tlalpan, 14080 México, D. F.

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December 2002

Estrogen receptor expression in giant cell tumors of the bone.

Hum Pathol 2002 Feb;33(2):165-9

Laboratorio de Biología Molecular, División de Investigación Básica, Instituto Nacional de Cancerología, Mexico City, Mexico.

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http://dx.doi.org/10.1053/hupa.2002.31476DOI Listing
February 2002