Jorge Duconge

Jorge Duconge

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Jorge Duconge

Jorge Duconge

Publications by authors named "Jorge Duconge"

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62Publications

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Pharmacokinetics of the Rac/Cdc42 Inhibitor MBQ-167 in Mice by Supercritical Fluid Chromatography-Tandem Mass Spectrometry.

ACS Omega 2019 Nov 23;4(19):17981-17989. Epub 2019 Oct 23.

Department of Biochemistry and Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico Medical Sciences Campus, PO Box 365067, San Juan, Puerto Rico 00936-5067, United States.

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http://dx.doi.org/10.1021/acsomega.9b01641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843717PMC
November 2019

Low-frequency variants at the locus among Puerto Rican patients on warfarin: predictions of functionality and conservation.

Pharmacogenomics 2019 08;20(12):891-902

Department of Pharmaceutical Sciences, Medical Sciences Campus, School of Pharmacy, University of Puerto Rico, San Juan, PR 00936-5067, USA.

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http://dx.doi.org/10.2217/pgs-2019-0051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739902PMC
August 2019

CYP2C9*61, a rare missense variant identified in a Puerto Rican patient with low warfarin dose requirements.

Pharmacogenomics 2019 01 6;20(1):3-8. Epub 2018 Dec 6.

Department of Pharmaceutical Sciences, School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, Puerto Rico.

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http://dx.doi.org/10.2217/pgs-2018-0143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479273PMC
January 2019

Preventing the exacerbation of health disparities by iatrogenic pharmacogenomic applications: lessons from warfarin.

Pharmacogenomics 2018 07 14;19(11):875-881. Epub 2018 Jun 14.

Institute of Living at Hartford Hospital, Hartford, CT 06102, USA.

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http://dx.doi.org/10.2217/pgs-2018-0055DOI Listing
July 2018

Potential Usefulness of Clopidogrel Pharmacogenetics in Cerebral Endovascular Procedures and Carotid Artery Stenting.

Curr Clin Pharmacol 2017 ;12(1):11-17

Department of Medicine, School of Medicine, University of Puerto Rico Medical Sciences Campus (UPR-MSC), San Juan, PR, United States.

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http://dx.doi.org/10.2174/1574884712666170227154654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478430PMC
April 2018

A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO MIRCERA and iorEPOCIM.

J Pharm Pharmacogn Res 2018 May-Jun;6(3):179-190. Epub 2018 Feb 23.

Department of Pharmacy, Institute of Pharmacy & Foods, University of Havana, 222 St. and 23 Av. La Coronela, La Lisa, 13600, Havana, Cuba.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364991PMC
February 2018

Clinical determinants of clopidogrel responsiveness in a heterogeneous cohort of Puerto Rican Hispanics.

Ther Adv Cardiovasc Dis 2017 Sep 4;11(9):235-241. Epub 2017 Jul 4.

Pharmaceutical Sciences Department, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA.

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http://dx.doi.org/10.1177/1753944717718718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555769PMC
September 2017

Admixture and ethno-specific alleles: missing links for global pharmacogenomics.

Pharmacogenomics 2016 09 18;17(14):1479-82. Epub 2016 Aug 18.

Pharmaceutical Sciences Department, Genomas Inc., Hartford, CT 06102, USA.

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http://dx.doi.org/10.2217/pgs-2016-0115DOI Listing
September 2016

Fixed-dose combination products and unintended drug interactions: urgent need for pharmacogenetic evaluation.

Pharmacogenomics 2015 2;16(15):1685-8. Epub 2015 Oct 2.

Genomas Inc., Hartford, CT 06106, USA.

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http://dx.doi.org/10.2217/pgs.15.123DOI Listing
July 2016

Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2015 Feb 2;981-982:19-26. Epub 2015 Jan 2.

Department of Biochemistry, School of Medicine, University of Puerto Rico, San Juan, PR, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2014.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306626PMC
February 2015

CYP2D6's functional status associated with the length of hospitalization stay in psychiatric patients: a twist in the tale or evidence that matters?

Biomark Med 2013 Dec;7(6):913-4

School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, San Juan, PR 00936-5067, Puerto Rico.

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http://dx.doi.org/10.2217/bmm.13.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109677PMC
December 2013

The bio-energetic theory of carcinogenesis.

Med Hypotheses 2012 Oct 17;79(4):433-9. Epub 2012 Jul 17.

University of Puerto Rico, Medical Sciences Campus, School of Public Health and Pharmacy, RECNAC2 Program, San Juan, PR 00936-5067, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03069877120029
Publisher Site
http://dx.doi.org/10.1016/j.mehy.2012.06.015DOI Listing
October 2012

The Emerging Role of Admixture in the Pharmacogenetics of Puerto Rican Hispanics.

J Pharmacogenomics Pharmacoproteomics 2010 Oct;1(101)

University of Puerto Rico School of Pharmacy, Medical Sciences Campus, Pharmaceutical Sciences Department, San Juan PR 00936.

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http://dx.doi.org/10.4172/2153-0645.1000101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515058PMC
October 2010

Implementing genotype-guided antithrombotic therapy.

Future Cardiol 2010 May;6(3):409-24

Genomas, Inc., 67 Jefferson Street, Hartford, CT 06106, USA.

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http://dx.doi.org/10.2217/fca.10.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903229PMC
May 2010

Applying organ clearance concepts in a clinical setting.

Authors:
Jorge Duconge

Am J Pharm Educ 2008 Oct;72(5):121

University of Puerto Rico School of Pharmacy, Medical Sciences Campus, Pharmaceutical Sciences Department, PO Box 365067, San Juan, PR 00936-5067.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630146PMC
http://dx.doi.org/10.5688/aj7205121DOI Listing
October 2008

High carrier prevalence of combinatorial CYP2C9 and VKORC1 genotypes affecting warfarin dosing.

Per Med 2008 May;5(3):225-232

University of California, San Francisco, Department of Laboratory Medicine, Clinical Chemistry Laboratory, San Francisco General Hospital; 1001 Portero Avenue, San Francisco, CA 94110, USA.

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http://dx.doi.org/10.2217/17410541.5.3.225DOI Listing
May 2008

Pharmacokinetics of vitamin C: insights into the oral and intravenous administration of ascorbate.

P R Health Sci J 2008 Mar;27(1):7-19

Department of Pharmaceutical Sciences, Suite 413C, School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, PO Box 365067, San Juan, PR 00936-5067.

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March 2008

Kinetics of monoclonal anti-epidermal growth factor receptor antibody (IOR EGF/r3)-induced apoptosis in human carcinoma bearing nude mice.

P R Health Sci J 2008 Mar;27(1):35-41

Department of Pharmacology & Toxicology, Center for Biological Evaluation and Research Institute of Pharmacy & Foods, University of Havana, Havana 36, CP 13600, Cuba.

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March 2008

Biodistribution of liposome-entrapped human gamma-globulin.

Biopharm Drug Dispos 2006 Sep;27(6):275-83

Molecular Biology Department, Division of Biotechnology, Finlay Institute, Havana City, Cuba.

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http://dx.doi.org/10.1002/bdd.511DOI Listing
September 2006

The case of biotech-derived product equivalence: much ado about nothing?

Authors:
Jorge Duconge

Curr Clin Pharmacol 2006 May;1(2):147-56

Department of Pharmaceutical Sciences, School of Pharmacy, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936-5067.

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http://dx.doi.org/10.2174/157488406776872523DOI Listing
May 2006

Pharmacokinetic comparison of two recombinant human granulocyte colony-stimulating factor after subcutaneous administration in rabbits.

Eur J Pharm Biopharm 2005 Oct 29;61(3):142-8. Epub 2005 Aug 29.

Department of Pharmacology and Toxicology, Center for Biological Evaluation and Research, Institute of Pharmacy & Foods, University of Havana.

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http://dx.doi.org/10.1016/j.ejpb.2005.06.003DOI Listing
October 2005

Interspecies scaling of the monoclonal anti-EGF receptor ior EGF/r3 antibody disposition using allometric paradigm: is it really suitable?

Biopharm Drug Dispos 2004 May;25(4):177-86

Laboratory of Biopharmaceutics, Department of Pharmacology, Institute of Pharmacy and Foods, University of Havana, Cuba.

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http://dx.doi.org/10.1002/bdd.398DOI Listing
May 2004

Integrated pharmacokinetic-pharmacodynamic modeling and allometric scaling for optimizing the dosage regimen of the monoclonal ior EGF/r3 antibody.

Eur J Pharm Sci 2004 Feb;21(2-3):261-70

Department of Pharmacology and Toxicology, Institute of Pharmacy and Foods, University of Havana, 222 St. and 23rd. Avenue, La Coronela, La Lisa, Havana 36 CP 13600, Cuba.

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http://dx.doi.org/10.1016/j.ejps.2003.10.015DOI Listing
February 2004