Publications by authors named "Jorge A Suby"

2 Publications

  • Page 1 of 1

Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence.

Int J Paleopathol 2015 Dec 17;11:92-101. Epub 2015 Nov 17.

Instituto de Bioantropología, Museo de la Naturaleza y el Hombre, Tenerife, Islas Canarias, Spain.

This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierra del Fuego, Constantinescu (1999) briefly described vertebral bone lesions compatible with TB in an undated skeleton from Myren 1 site (Chile). The remains of Myren are estimated to represent a man between 18 and 23 years old at the time of death. The objectives of this research are to extend this description, to present molecular results, to establish a radiocarbon date, and to report stable isotopic values for the remains. We provide further description of the remains, including tuberculosis-like skeletal pathology. Radiocarbon dating of 640±20 years BP attributes this individual to the precontact fourteenth-fifteenth centuries. Isotopic ratios for nitrogen and carbon from bone collagen suggest a mixed diet. Molecular results were positive for the rpoB quantitative PCR (qPCR) assays but negative for two independent IS6110 and IS1081 qPCR assays. Further testing using genomic methods to target any mycobacteria for specific identification are needed.
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http://dx.doi.org/10.1016/j.ijpp.2015.09.003DOI Listing
December 2015

A case of adult osteomyelitis in a Final Late Holocene hunter-gatherer population, eastern Pampa-Patagonian transition, Argentina.

Int J Paleopathol 2013 Jun 15;3(2):128-133. Epub 2013 Jun 15.

INCUAPA-CONICET, Facultad de Ciencias Sociales, UNICEN, Avda. del Valle 5737, Olavarría B7400JWI, Argentina. Electronic address:

Osteomyelitis was frequent in prehistoric times, although its paleopathological recognition and analysis in skeletal remains is typically incomplete. Contrasting with osteomyelitis in children, in adults it is usually a subacute or chronic infection that develops secondary to an open injury. The aim of this paper is to present a case of osteomyelitis in an adult female skeleton, from a hunter-gatherer population that inhabited the eastern Pampa-Patagonian transition (Argentina) during Final Late Holocene (ca. 250 years BP). Macroscopic studies as well as biplanar radiographs and CT scans were used for diagnosis. Lamellar bone formations on the diaphysis and in the interior of the marrow cavity were recorded. Also, a lytic lesion was identified in CT images. The diagnostic procedures and the probable causes that could generate the lesions in the long bones of the lower limb are discussed. The lesions are consistent with osteomyelitis secondary to a contiguous focus of infection, possibly linked to the abscess in the maxillary bone.
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http://dx.doi.org/10.1016/j.ijpp.2013.05.002DOI Listing
June 2013