Jordi Bonaventura

Jordi Bonaventura

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Jordi Bonaventura

Jordi Bonaventura

Publications by authors named "Jordi Bonaventura"

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18Publications

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Ultrapotent chemogenetics for research and potential clinical applications.

Science 2019 04 14;364(6436). Epub 2019 Mar 14.

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.

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http://dx.doi.org/10.1126/science.aav5282DOI Listing
April 2019

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine.

Science 2017 08;357(6350):503-507

Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse (NIDA) Intramural Research Program, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1126/science.aan2475DOI Listing
August 2017

Key role of the dopamine D receptor in the modulation of corticostriatal glutamatergic neurotransmission.

Sci Adv 2017 Jan 11;3(1):e1601631. Epub 2017 Jan 11.

Integrative Neurobiology Section, National Institute on Drug Abuse, Intramural research Program, National Institutes of Health, Baltimore, MD 21224, USA.

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http://advances.sciencemag.org/lookup/doi/10.1126/sciadv.160
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http://dx.doi.org/10.1126/sciadv.1601631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226642PMC
January 2017

Adenosine receptors as markers of brain iron deficiency: Implications for Restless Legs Syndrome.

Neuropharmacology 2016 12 4;111:160-168. Epub 2016 Sep 4.

Integrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056844PMC
http://dx.doi.org/10.1016/j.neuropharm.2016.09.002DOI Listing
December 2016

Equilibrative nucleoside transporter ENT1 as a biomarker of Huntington disease.

Neurobiol Dis 2016 Dec 24;96:47-53. Epub 2016 Aug 24.

Integrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961163020
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http://dx.doi.org/10.1016/j.nbd.2016.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102769PMC
December 2016

Evidence for the heterotetrameric structure of the adenosine A2A-dopamine D2 receptor complex.

Biochem Soc Trans 2016 Apr;44(2):595-600

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 28031 Madrid, Spain Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain Institute of Biomedicine of the University of Barcelona (IBUB), 08028 Barcelona, Spain

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http://dx.doi.org/10.1042/BST20150276DOI Listing
April 2016

Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer.

Proc Natl Acad Sci U S A 2015 Jul 22;112(27):E3609-18. Epub 2015 Jun 22.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, and Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas and Institute of Biomedicine of the University of Barcelona, 08028 Barcelona, Spain;

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http://dx.doi.org/10.1073/pnas.1507704112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500251PMC
July 2015

A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors.

Eur J Med Chem 2015 Jun 28;97:173-80. Epub 2015 Apr 28.

Combinatorial Chemistry Unit, Barcelona Science Park, University of Barcelona, 08028 Barcelona, Spain; CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Barcelona Science Park, 08028 Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.04.052DOI Listing
June 2015

L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus.

Neuropharmacology 2014 Apr 11;79:90-100. Epub 2013 Nov 11.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain; Centro de Investigación Médica Aplicada, Universidad de Navarra, 31008 Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2013.10.036DOI Listing
April 2014

L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies.

Exp Neurol 2014 Mar 9;253:180-91. Epub 2014 Jan 9.

Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain; Centro de Investigación Médica Aplicada, Universidad de Navarra, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1016/j.expneurol.2013.12.021DOI Listing
March 2014

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers.

PLoS One 2013 18;8(4):e61245. Epub 2013 Apr 18.

Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED) and Institute of Biomedicine of the University of Barcelona (IBUB) and Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061245PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630156PMC
December 2013

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.

Biochem Pharmacol 2009 Dec 28;78(12):1456-63. Epub 2009 Jul 28.

Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, Avda. Diagonal 465, 08028 Barcelona, Spain.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520900642
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http://dx.doi.org/10.1016/j.bcp.2009.07.012DOI Listing
December 2009