Jordan Jarjour

Jordan Jarjour

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Jordan Jarjour

Jordan Jarjour

Publications by authors named "Jordan Jarjour"

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17Publications

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Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance.

Mol Ther Nucleic Acids 2016 Aug 23;5(8):e352. Epub 2016 Aug 23.

Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/mtna.2016.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023401PMC
August 2016

Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.

Structure 2016 06 28;24(6):862-73. Epub 2016 Apr 28.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, A3-025, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899242PMC
June 2016

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.

Sci Transl Med 2015 Sep;7(307):307ra156

Center for Immunity and Immunotherapies and Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA 98101, USA. Department of Pediatrics, University of Washington, Seattle, WA 98101, USA. Department of Immunology, University of Washington, Seattle, WA 98101, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac5530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790757PMC
September 2015

Fanconi anemia gene editing by the CRISPR/Cas9 system.

Hum Gene Ther 2015 Feb;26(2):114-26

1 Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota , Minneapolis, MN 55455.

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http://dx.doi.org/10.1089/hum.2014.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326027PMC
February 2015

The design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene drive.

PLoS One 2013 10;8(9):e74254. Epub 2013 Sep 10.

Department of Genetics, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074254PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769382PMC
June 2014

Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus.

Nucleic Acids Res 2014 Jun 25;42(10):6463-75. Epub 2014 Mar 25.

Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101, USA Departments of Pediatrics and Immunology, University of Washington, Seattle, WA 98195, USA

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http://dx.doi.org/10.1093/nar/gku224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041414PMC
June 2014

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.

Nucleic Acids Res 2014 Feb 26;42(4):2591-601. Epub 2013 Nov 26.

Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA, Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101, USA, Pregenen, Inc., Seattle, WA 98103, USA, Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA, Cellectis S.A., Paris, 75013, France, Division of Basic Sciences, Fred Hutch Cancer Research Center, Seattle, WA 98109, USA, Department of Biochemistry, University of Washington, Seattle, WA 98195, USA, Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA and Department of Immunology, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1093/nar/gkt1224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936731PMC
February 2014

LAHEDES: the LAGLIDADG homing endonuclease database and engineering server.

Nucleic Acids Res 2012 Jul 8;40(Web Server issue):W110-6. Epub 2012 May 8.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/nar/gks365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394308PMC
July 2012

Tracking genome engineering outcome at individual DNA breakpoints.

Nat Methods 2011 Jul 10;8(8):671-6. Epub 2011 Jul 10.

Program in Molecular and Cellular Biology, University of Washington, Seattle, Washington, USA.

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http://www.nature.com/articles/nmeth.1648
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http://dx.doi.org/10.1038/nmeth.1648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415300PMC
July 2011

Exploitation of binding energy for catalysis and design.

Nature 2009 Oct;461(7268):1300-4

Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1038/nature08508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771326PMC
October 2009