Joost van den Oord

Joost van den Oord

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Joost van den Oord

Publications by authors named "Joost van den Oord"

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A variant in FTO gene shows association with histological ulceration in cutaneous melanoma.

J Cutan Pathol 2019 Aug 30. Epub 2019 Aug 30.

Department of Dermatology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/cup.13575DOI Listing
August 2019

Molecular profiling of Spitz nevi identified by digital RNA counting.

Melanoma Res 2018 12;28(6):510-520

Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center.

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http://dx.doi.org/10.1097/CMR.0000000000000495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221391PMC
December 2018

Genomic Landscape of Spitzoid Neoplasms Impacting Patient Management.

Front Med (Lausanne) 2018 13;5:344. Epub 2018 Dec 13.

Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands.

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http://dx.doi.org/10.3389/fmed.2018.00344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300473PMC
December 2018

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.

Cell Stem Cell 2017 Nov 12;21(5):679-693.e6. Epub 2017 Oct 12.

Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, 3000 Leuven, Belgium; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.003DOI Listing
November 2017

Response to targeted therapy in two patients with metastatic melanoma carrying rare BRAF exon 15 mutations: A598_T599insV and V600_K601delinsE.

Melanoma Res 2017 10;27(5):507-510

aDepartment of General Medical Oncology bDepartment of Human Genetics, Center for Human Genetics cDepartment of Pathology dDepartment of Oncological Surgery eDepartment of Dermatology, University Hospitals KU Leuven, Leuven fDepartment of Hematology and Medical Oncology, ;CHR East Belgium, Verviers, Belgium.

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http://dx.doi.org/10.1097/CMR.0000000000000376DOI Listing
October 2017

Molecular genetic and immunotherapeutic targets in metastatic melanoma.

Virchows Arch 2017 Aug 29;471(2):281-293. Epub 2017 Mar 29.

Department of Pathology, University Hospitals of Leuven, University of Leuven KUL, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00428-017-2113-3DOI Listing
August 2017

Immunohistochemical Profiling of Corneas With Fuchs Endothelial Corneal Dystrophy.

Cornea 2017 Jul;36(7):866-874

*Laboratory for Translational Cell & Tissue Research, Department of Imaging & Pathology, KU Leuven-University of Leuven, Leuven, Belgium; †Department of Pathology, UZ Leuven-University Hospitals Leuven, Leuven, Belgium; ‡Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven-University of Leuven, Leuven, Belgium; §Department of Ophthalmology, UZ Leuven-University Hospitals Leuven, Leuven, Belgium; and ¶Research Group Ophthalmology, Department of Neurosciences, KU Leuven-University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/ICO.0000000000001212DOI Listing
July 2017

Immunoplasticity in cutaneous melanoma: beyond pure morphology.

Virchows Arch 2017 04 5;470(4):357-369. Epub 2017 Jan 5.

Laboratory of Translational Cell and Tissue Research, KUL, Minderbroederstraat 19, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00428-016-2058-yDOI Listing
April 2017

The effect of L-PRF membranes on bone healing in rabbit tibiae bone defects: micro-CT and biomarker results.

Sci Rep 2017 04 12;7:46452. Epub 2017 Apr 12.

KU Leuven &University Hospitals Leuven, Department of Oral Health Sciences, BIOMAT KU Leuven &Prosthetics section, Leuven, Belgium.

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http://dx.doi.org/10.1038/srep46452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388884PMC
April 2017

Identification of a novel species of papillomavirus in giraffe lesions using nanopore sequencing.

Vet Microbiol 2017 Mar 30;201:26-31. Epub 2016 Dec 30.

KU Leuven - University of Leuven, Department of Microbiology and Immunology, Laboratory of Clinical Virology, Rega Institute for Medical Research, Herestraat 49/Box 1040, BE3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.vetmic.2016.12.035DOI Listing
March 2017

Identification of Circulating Fibrocytes and Dendritic Derivatives in Corneal Endothelium of Patients With Fuchs' Dystrophy.

Invest Ophthalmol Vis Sci 2017 01;58(1):670-681

Department of Imaging & Pathology, Laboratory for Translational Cell & Tissue Research, KU Leuven - University of Leuven, Leuven, Belgium 2Department of Pathology, UZ Leuven - University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1167/iovs.16-20880DOI Listing
January 2017

Plasma cells in primary melanoma. Prognostic significance and possible role of IgA.

Mod Pathol 2016 Apr 12;29(4):347-58. Epub 2016 Feb 12.

Laboratory of Translational Cell and Tissue Research, University of Leuven, KUL, Leuven, Belgium.

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http://dx.doi.org/10.1038/modpathol.2016.28DOI Listing
April 2016

Transforming Growth Factor Beta Switch in Aqueous Humor of Patients With Fuchs' Endothelial Corneal Dystrophy.

Invest Ophthalmol Vis Sci 2016 Feb;57(2):771-2

Translational Cell & Tissue Research Department of Imaging & Pathology, KU Leuven, Belgium; Department of Pathology, UZ Leuven, Belgium;

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http://dx.doi.org/10.1167/iovs.15-18768DOI Listing
February 2016

Novel Therapies for Metastatic Melanoma: An Update on Their Use in Older Patients.

Drugs Aging 2015 Oct;32(10):821-34

Department of General Medical Oncology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s40266-015-0304-7DOI Listing
October 2015

Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma.

J Invest Dermatol 2015 Sep 28;135(9):2328-2331. Epub 2015 Apr 28.

Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.163DOI Listing
September 2015

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma.

EBioMedicine 2015 Sep 1;2(9):1102-13. Epub 2015 Aug 1.

KU Leuven, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ebiom.2015.07.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588406PMC
September 2015

Mass Spectrometry of Flame Figures.

Acta Derm Venereol 2015 Jul;95(6):734-5

Translational Cell and Tissue Research, Dept. of Imaging and Pathology, University of Leuven (KU Leuven), 3000 Leuven, Belgium.

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http://www.medicaljournals.se/acta/content/?doi=10.2340/0001
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http://dx.doi.org/10.2340/00015555-2050DOI Listing
July 2015

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.

Nat Med 2015 Jul 1;21(7):741-50. Epub 2015 Jun 1.

1] Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, L'Hospitalet, Barcelona, Catalonia, Spain. [2] Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain. [3] Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/nm.3863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968631PMC
July 2015

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.

Melanoma Res 2015 Jun;25(3):189-99

aOncoMark Ltd, NovaUCD bDepartment of Medical Oncology, Royal College of Surgeons cUCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin Departments of dPathology eSurgery fMedical Oncology, St Vincent's University Hospital gDepartment of Histopathology, Royal College of Surgeons in Ireland Education and Research Centre, Beaumont Hospital hDepartment of Histopathology, St James's Hospital iDepartment of Histopathology, Trinity College, Dublin jDepartment of Pathology, Cork University Hospital, Cork Departments of kSurgery lMedical Oncology, University Hospital Galway mDepartment of Medicine, National University of Ireland Galway nDepartment of Histopathology, University Hospital Galway, Galway, Ireland oDepartment of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands pLaboratory of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CMR.0000000000000149DOI Listing
June 2015

Promoter CpG island hypermethylation in dysplastic nevus and melanoma: CLDN11 as an epigenetic biomarker for malignancy.

J Invest Dermatol 2014 Dec 7;134(12):2957-2966. Epub 2014 Jul 7.

Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands; The first two and last three authors contributed equally to this work. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.270DOI Listing
December 2014

BRAFV600E immunopositive melanomas show low frequency of heterogeneity and association with epithelioid tumor cells: a STROBE-compliant article.

Medicine (Baltimore) 2014 Dec;93(28):e285

From the Department of Pathology, Maastricht University Medical Centre, Maastricht, The Netherlands (IV, KvdH, CMHAS, GMJMR, AzH, E-JMS, VJLW); GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands (KvdH, AzH, E-JMS, VJLW); Department of Clinical Pathology, Atrium Medical Centre Parkstad, Heerlen, The Netherlands (RC); Department of Pathology, St. Laurentius ziekenhuis, Roermond, The Netherlands (APW); and Laboratory of Translational Cell & Tissue Research and Department of Pathology, University Hospital, KULeuven, Leuven, Belgium (JJvdO).

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https://insights.ovid.com/crossref?an=00005792-201412030-000
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http://dx.doi.org/10.1097/MD.0000000000000285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603111PMC
December 2014

Tissue microarray.

J Invest Dermatol 2014 Sep;134(9):1-4

Laboratory of Dermatology, Department of Oncology, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.277DOI Listing
September 2014

A novel hypoxia-associated subset of FN1 high MITF low melanoma cells: identification, characterization, and prognostic value.

Mod Pathol 2014 Aug 3;27(8):1088-100. Epub 2014 Jan 3.

Translational Cell and Tissue Research, Department of Imaging and Pathology, University of Leuven (KU Leuven), Leuven, Belgium.

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http://dx.doi.org/10.1038/modpathol.2013.228DOI Listing
August 2014

A new and standardized method to sample and analyse vitreous samples by the Cellient automated cell block system.

Acta Ophthalmol 2014 Aug 7;92(5):e388-92. Epub 2014 Feb 7.

Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/aos.12360DOI Listing
August 2014

Clinical presentation, pathological features and natural course of metastatic uveal melanoma, an orphan and commonly fatal disease.

Oncology 2014 23;86(3):185-9. Epub 2014 Apr 23.

Department of General Medical Oncology and Laboratory of Experimental Oncology, University Hospitals and Catholic University Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1159/000358729DOI Listing
June 2014

The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis.

PLoS One 2013 3;8(10):e76550. Epub 2013 Oct 3.

Translational Cell & Tissue Research, Dept. of Imaging and Pathology, University of Leuven (KU Leuven), Leuven, Belgium ; Research Unit of Stem Cell Research (Lab. of Tissue Plasticity), Cluster Stem Cell Biology and Embryology, Dept. of Development and Regeneration, University of Leuven (KU Leuven), Leuven, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789681PMC
April 2014

Quantitative proteomics profiling of primary lung adenocarcinoma tumors reveals functional perturbations in tumor metabolism.

J Proteome Res 2013 Sep 13;12(9):3934-43. Epub 2013 Aug 13.

Cancer Proteomics Mass Spectrometry, Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1021/pr4002096DOI Listing
September 2013

Choroidal paraganglioma with metastases to the fellow eye.

Case Rep Ophthalmol 2013 Jan 25;4(1):17-22. Epub 2013 Feb 25.

Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium ; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1159/000347169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604866PMC
January 2013

Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression.

Virchows Arch 2012 Oct 6;461(4):441-8. Epub 2012 Sep 6.

Lady Davis Institute for Medical Research, Jewish General Hospital, LDI-E447, 3755 Cote Ste-Catherine, Montreal, QC, Canada H3T 1E2.

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http://dx.doi.org/10.1007/s00428-012-1309-9DOI Listing
October 2012

Genetics and epigenetics of cutaneous malignant melanoma: a concert out of tune.

Biochim Biophys Acta 2012 Aug 31;1826(1):89-102. Epub 2012 Mar 31.

Department of Pathology, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.bbcan.2012.03.011DOI Listing
August 2012

Neogenesis of lymphoid structures and antibody responses occur in human melanoma metastases.

Cancer Res 2012 Aug 31;72(16):3997-4007. Epub 2012 Jul 31.

de Duve Institute, Université catholique de Louvain, Bruxelles, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1377DOI Listing
August 2012

Gene expression changes in melanoma metastases in response to high-dose chemotherapy during isolated limb perfusion.

Pigment Cell Melanoma Res 2012 Jul 3;25(4):454-65. Epub 2012 May 3.

Translational Cell & Tissue Research, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/j.1755-148X.2012.01004.xDOI Listing
July 2012

Antigenic profiles of individual-matched pairs of primary and melanoma metastases.

Hum Pathol 2009 Oct 22;40(10):1399-407. Epub 2009 Apr 22.

Department of Pathology, Academical Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.humpath.2008.11.018DOI Listing
October 2009

Porphyria cutanea tarda and liver disease. A retrospective analysis of 17 cases from a single centre and review of the literature.

Acta Gastroenterol Belg 2008 Apr-Jun;71(2):237-42

Department of Hepatology, University Hospital Gasthuisberg, University of Leuven, Belgium.

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September 2008

The CCR9-CCL25 axis mediates melanoma metastasis to the small intestine.

Nat Clin Pract Oncol 2008 Aug 24;5(8):440-1. Epub 2008 Jun 24.

Laboratory of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/ncponc1174DOI Listing
August 2008

Expression profiling of melanoma cell lines: in search of a progression-related molecular signature.

Future Oncol 2007 Dec;3(6):609-11

Katholieke Universiteit Leuven, Department of Pathology, Morphology & Molecular Pathology Laboratory, University Hospitals Minderbroedersstraat 12, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.2217/14796694.3.6.609DOI Listing
December 2007

Gene expression profiling and clinical outcome in melanoma: in search of novel prognostic factors.

Expert Rev Anticancer Ther 2007 Nov;7(11):1611-31

Universiteit Maastricht, University Hospital, P. Debyelaan 25, Postbus 5800, 6202 AZ, Maastricht, The Netherlands.

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http://dx.doi.org/10.1586/14737140.7.11.1611DOI Listing
November 2007

Expression and possible role of hPTTG1/securin in cutaneous malignant melanoma.

Mod Pathol 2006 Sep 23;19(9):1170-80. Epub 2006 Jun 23.

Department of Morphology and Molecular Pathology, University Hospitals, Katholieke Universiteit Leuven (KUL), Leuven, Belgium.

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http://dx.doi.org/10.1038/modpathol.3800627DOI Listing
September 2006

Organotypic epithelial raft cultures as a model for evaluating compounds against alphaherpesviruses.

Antimicrob Agents Chemother 2005 Nov;49(11):4671-80

Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1128/AAC.49.11.4671-4680.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280113PMC
November 2005

Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)--associated TORC1-MAML2 gene fusion.

Genes Chromosomes Cancer 2005 Jun;43(2):202-5

Lundberg Laboratory for Cancer Research, Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://doi.wiley.com/10.1002/gcc.20168
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http://dx.doi.org/10.1002/gcc.20168DOI Listing
June 2005

Immunophenotype and possible origin of nevi with phenotypical heterogeneity.

Arch Dermatol Res 2004 Jul 13;296(2):49-53. Epub 2004 May 13.

Department of Pathology, Laboratory of Morphology and Molecular Pathology, University Hospital St-Rafael, Minderbroedersstraat 12, Leuven, Belgium.

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http://dx.doi.org/10.1007/s00403-004-0471-6DOI Listing
July 2004

New phenotypical and ultrastructural findings in spindle cell (desmoplastic/neurotropic) melanoma.

Appl Immunohistochem Mol Morphol 2003 Dec;11(4):319-25

Department of Pathology, Laboratory of Morphology and Molecular Pathology, University Hospital St-Raphael, Katholieke Universiteit Leuven, Minderbroedersstraat 12, B-3000 Leuven, Belgium.

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December 2003

Pathologic staging of melanoma.

Semin Oncol 2002 Aug;29(4):370-81

Department of Pathology, University Medical Center St Radboud, Nijmegen, The Netherland.

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August 2002

Gelatinase B deficiency protects against endotoxin shock.

Eur J Immunol 2002 Aug;32(8):2163-71

Rega Institute, Laboratory of Molecular Immunology, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/1521-4141(200208)32:8<2163::AID-IMMU2163>3.0.CO;2-QDOI Listing
August 2002

Local treatment of HPV-induced skin lesions by Cidofovir.

J Med Virol 2002 Jun;67(2):241-5

Department of Dermatology, U.Z. Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/jmv.2213DOI Listing
June 2002

Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations.

Mod Pathol 2002 Apr;15(4):454-61

Department of Pathology, Laboratory of Morphology and Molecular Pathology, University Hospitals, Katholieke Universiteit Leuven, Belgium.

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http://www.nature.com/articles/3880546
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http://dx.doi.org/10.1038/modpathol.3880546DOI Listing
April 2002