Publications by authors named "Joost Kok"

17Publications

Dynamic vehicle routing with time windows in theory and practice.

Nat Comput 2017 9;16(1):119-134. Epub 2016 Apr 9.

Leiden Institute of Advanced Computer Science, Leiden University, Niels Bohrweg 1, 2333 CA Leiden, The Netherlands.

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http://link.springer.com/10.1007/s11047-016-9550-9
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http://dx.doi.org/10.1007/s11047-016-9550-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309326PMC
April 2016

An efficient algorithm for the extraction of HGVS variant descriptions from sequences.

Bioinformatics 2015 Dec 31;31(23):3751-7. Epub 2015 Jul 31.

Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, Leiden Genome Technology Center, Leiden University Medical Center, Leiden, The Netherlands.

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http://bioinformatics.oxfordjournals.org/content/early/2015/
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http://bioinformatics.oxfordjournals.org/content/early/2015/
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http://bioinformatics.oxfordjournals.org/lookup/doi/10.1093/
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http://dx.doi.org/10.1093/bioinformatics/btv443DOI Listing
December 2015

The Open Physiology workflow: modeling processes over physiology circuitboards of interoperable tissue units.

Front Physiol 2015 24;6:24. Epub 2015 Feb 24.

Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh Edinburgh, UK.

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http://dx.doi.org/10.3389/fphys.2015.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338662PMC
March 2015

Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging.

Aging Cell 2014 Apr 19;13(2):216-25. Epub 2013 Nov 19.

Department of Molecular Epidemiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands; The Delft Bioinformatics Lab, Delft University of Technology, PO Box 5031, 2600 GA, Delft, The Netherlands.

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http://dx.doi.org/10.1111/acel.12160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331790PMC
April 2014

Clinical subtypes of Parkinson's disease.

Mov Disord 2011 Jan 16;26(1):51-8. Epub 2010 Nov 16.

Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/mds.23346DOI Listing
January 2011

Finding discriminative subtypes of aggressive brain tumours using magnetic resonance spectroscopy.

Annu Int Conf IEEE Eng Med Biol Soc 2010 ;2010:1065-8

Center for Neurobehavioral Genetics, University of California Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1109/IEMBS.2010.5627286DOI Listing
March 2011

The identification of Parkinson's disease subtypes using cluster analysis: a systematic review.

Mov Disord 2010 Jun;25(8):969-78

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/mds.23116DOI Listing
June 2010

GPCR NaVa database: natural variants in human G protein-coupled receptors.

Hum Mutat 2008 Jan;29(1):39-44

Division of Medicinal Chemistry, Leiden-Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/humu.20638DOI Listing
January 2008

DNA computing of solutions to knapsack problems.

Biosystems 2007 Mar 10;88(1-2):156-62. Epub 2006 Jun 10.

Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.biosystems.2006.06.001DOI Listing
March 2007

TreeSOM: Cluster analysis in the self-organizing map.

Neural Netw 2006 Jul-Aug;19(6-7):935-49. Epub 2006 Jun 15.

Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Einsteinweg 55, 2333CC Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.neunet.2006.05.003DOI Listing
October 2006

Substructure mining using elaborate chemical representation.

J Chem Inf Model 2006 Mar-Apr;46(2):597-605

Division of Medicinal Chemistry, Leiden-Amsterdam Center for Drug Research, Leiden University, P.O. Box 9502, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/ci0503715DOI Listing
September 2006

Mining a chemical database for fragment co-occurrence: discovery of "chemical clichés".

J Chem Inf Model 2006 Mar-Apr;46(2):553-62

Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Einsteinweg 55, 2300 RA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/ci050370cDOI Listing
September 2006

The molecule evoluator. An interactive evolutionary algorithm for the design of drug-like molecules.

J Chem Inf Model 2006 Mar-Apr;46(2):545-52

Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, P.O. Box 9502, 2300RA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/ci050369dDOI Listing
September 2006