Joost Frenkel

Joost Frenkel

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Joost Frenkel

Publications by authors named "Joost Frenkel"

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Response to: 'Novel NLRP12 variant presenting with familial cold autoimmunity syndrome phenotype' by Gupta .

Ann Rheum Dis 2019 Sep 6. Epub 2019 Sep 6.

Paediatric Rheumatology, Istituto Giannina Gaslini, Genova, Italy.

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http://dx.doi.org/10.1136/annrheumdis-2019-216184DOI Listing
September 2019

Response to: 'Standard dose of ustekinumab for childhood-onset deficiency of interleukin-36 receptor antagonist' by Cherqaoui .

Ann Rheum Dis 2018 12 13;77(12):e89. Epub 2018 Jan 13.

Rheumatology Unit, G Gaslini Institute, Genova, Italy.

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http://dx.doi.org/10.1136/annrheumdis-2017-212832DOI Listing
December 2018

Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes.

N Engl J Med 2018 05;378(20):1908-1919

From the Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, Rome (F.D.B.), Clinica Pediatrica e Reumatologia, Unità Operativa Semplice Dipartimentale di Malattie Autoinfiammatorie e Immunodeficienze, IRCCS, Istituto G. Gaslini, Genoa (M.G.), the Pediatric Clinic, University of Brescia and Spedali Civili, Brescia (M.C.), and the Amyloidosis Research and Treatment Center, Biotechnology Research Laboratories, Fondazione IRCCS Policlinico San Matteo, Pavia (L.O.) - all in Italy; the Division of Pediatric Rheumatology, Hospital Sant Joan de Déu, Universitat de Barcelona (J.A.), and the Internal Medicine Department, Autoimmune and Systemic Diseases Unit, Hospital Vall d'Hebron (S.B.-R.), Barcelona, and the Pediatric Rheumatology Unit, Hospital Universitario y Politécnico La Fe, Valencia (I.C.P.) - all in Spain; the Rheumatology Unit, Hadassah-Hebrew University Hospital (E.B.-C.), and the Pediatric Rheumatology Unit, Shaare Zedek Medical Center (P.J.H.), Jerusalem, and Heller Institute of Medical Research and Medicine Faculty, Sheba Medical Center, Tel-Hashomer and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (A.L.) - all in Israel; the Division of Pediatrics, University Medical Center Utrecht, Utrecht (J.F.), and the Radboud Expertise Center for Immunodeficiency and Autoinflammation, Department of Internal Medicine, Radboud University Medical Center, Nijmegen (A. Simon) - both in the Netherlands; the Departments of Pediatrics and Medicine, University of California at San Diego and Rady Children's Hospital San Diego, San Diego (H.M.H.); the Department of Pediatric Rheumatology, Centre de Référence des Maladies Auto-inflammatoires et de l'Amylose Inflammatoire, Centre Hospitalier Universitaire (CHU) de Bicêtre, Assistance Publique-Hopitaux de Paris (APHP), Université de Paris Sud (I.K.-P.), and Paris-Descartes University, Imagine Institute, Unité d'Immuno-Hématologie et Rhumatologie Pédiatrique, Hôpital Necker-Enfants Malades, APHP (P.Q.), Paris; the National Amyloidosis Centre, University College London Division of Medicine, Royal Free Campus (H.J.L.), and University College London, Great Ormond Street Institute of Child Health, and Great Ormond Street Hospital for Children NHS Foundation Trust (P.B.), London; the Department of Pediatrics, Hacettepe University, Ankara (S.O.), and the Department of Pediatric Rheumatology, Cerrahpasa Medical School (O.K.), and Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology (A.G.), Istanbul University, Istanbul - all in Turkey; the Department of Pediatrics, Division of Pediatric Rheumatology, Cleveland Clinic, Cleveland (A.Z.); the Department of Infectious Diseases and General Internal Medicine, CHU Sart-Tilman, University of Liège, Liege (M.M.), and the Department of Infectious Diseases and Immunity, Jessa Hospital, University of Hasselt, Hasselt (J.V.H.) - both in Belgium; the Department of Clinical Immunology, Center for Pediatric Hematology, Oncology, and Immunology, Moscow (A. Shcherbina); Pediatric Rheumatology of Western Switzerland, University of Lausanne, Lausanne, (M.H.), and Novartis, Basel (K.L., A. Speziale, G.J.) - both in Switzerland; the Department of Pediatrics, Yokohama City University Graduate School of Medicine, Yokohama, Japan (R.H.); and the Department of Pediatrics, Semmelweis Egyetem, Budapest, Hungary (T.C.).

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http://dx.doi.org/10.1056/NEJMoa1706314DOI Listing
May 2018

Flexibility in Postgraduate Medical Training in the Netherlands.

Acad Med 2018 03;93(3S Competency-Based, Time-Variable Education in the Health Professions):S32-S36

R.G. Hoff is professor of education and training in perioperative, intensive, and emergency care and program director, Anesthesiology Residency, Department of Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands. J. Frenkel is professor of patient- and family-centered education and program director, Pediatrics Residency, Department of Pediatrics, University Medical Center Utrecht, Utrecht, The Netherlands. S.M. Imhof is professor of ophthalmology and program director, Ophthalmology Residency, Department of Ophthalmology, and chair, Central Residency Committee, University Medical Center Utrecht, Utrecht, The Netherlands. O. ten Cate is professor of medical education, Center for Research and Development of Education, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/ACM.0000000000002078DOI Listing
March 2018

The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey.

Pediatr Rheumatol Online J 2018 Mar 21;16(1):19. Epub 2018 Mar 21.

Department of General Pediatrics, University Medical Center Utrecht, Room KE 04 133 1, PO-Box 85090, 3508, AB Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s12969-018-0235-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863478PMC
March 2018

Juvenile interleukin-36 receptor antagonist deficiency (DITRA) with c.80T>C (p.Leu27Pro) mutation successfully treated with etanercept and acitretin.

JAAD Case Rep 2018 Mar 2;4(2):192-195. Epub 2018 Feb 2.

Department of Dermatology, Sophia Children's Hospital, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jdcr.2017.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993535PMC
March 2018

Response to: 'Autoinflammatory disease damage index (ADDI): a possible newborn also in hidradenitis suppurativa daily practice' by Damiani .

Ann Rheum Dis 2017 08 2;76(8):e26. Epub 2017 Jan 2.

Department of Paediatrics, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2016-210918DOI Listing
August 2017

Patient-Centered Teaching in a Technology-Dominated Era.

South Med J 2016 12;109(12):743-746

From the Division Child, Department of Pediatrics, and the Center for Research and Development of Education, University Medical Center Utrecht, Utrecht, the Netherlands, and the Department of Pediatrics, University of California, San Francisco.

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http://dx.doi.org/10.14423/SMJ.0000000000000569DOI Listing
December 2016

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease.

Oncotarget 2016 Apr;7(15):19265-71

Department of Pediatric Immunology, Wilhelmina Children's Hospital, UMC Utrecht, EA, Utrecht, Netherlands.

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http://dx.doi.org/10.18632/oncotarget.8086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991381PMC
April 2016

Performance of Different Diagnostic Criteria for Familial Mediterranean Fever in Children with Periodic Fevers: Results from a Multicenter International Registry.

J Rheumatol 2016 Jan 15;43(1):154-60. Epub 2015 Nov 15.

From the Familial Mediterranean Fever Arthritis Vasculitis and Orphan Disease Research Center (FAVOR), Gulhane Military Medical Faculty; Epidemiology, Gulhane Military Medical Faculty, Ankara, Turkey; Centre de référence national des maladies auto-inflammatoires, CEREMAI, Rhumatologie pédiatrique, CHU Le Kremlin Bicêtre (APHP, University of Paris SUD), Paris, France; Center of Paediatric and Adolescent Rheumatology, UCL, London, UK; Istituto Giannina Gaslini, UO Pediatria II, Reumatologia, Genoa, Italy; Arabkir Medical Centre, Institute of Child and Adolescents Health, Yerevan, Armenia; Department of Paediatrics, University Medical Center Utrecht, Utrecht, Netherlands; Pediatrics, Meir Medical Centre, Kfar Saba, Israel; Division of Rheumatology, Department of Pediatric Medicine, Bambino Gesù Children's Hospital, IRCCS, Rome; Rheumatology Unit, Policlinico le Scotte, University of Siena, Siena, Italy; Pediatrie, Centre Multisite Romand de Rhumatologie Pediatrique/Centre Hospitalier, Universitaire Vaudois (CHUV), Lausanne, Switzerland; Pediatric Rheumatology, Université Paris-Descartes, Paris, France; Pediatric Rheumatology, Hacettepe University, School of Medicine, Ankara, Turkey; Reumatologia, Hospital Valle de Hebron, Barcelona, Spain; Pediatrics, Università Cattolica Sacro Cuore, Rome, Italy; Fourth Department of Pediatrics, Aristotle University of Thessaloniki Papageorgiou Hospital, Thessaloniki, Greece; Universitatsklinik fur Kinderheilkunde und Jugendmedizin, Tübingen, Germany; Université Paris-Descartes, Hôpital Necker-Enfants Malades, Centre de référence national pour les Arthrites Juveniles, Unité d'Immunologie, Hématologie et Rhumatologie Pédiatrique, Université Descartes, Sorbonne Paris Cité, Institut IMAGINE, Paris, France; National Amyloidosis Centre, University College London Medical School, Royal Free Campus, London, UK.E. Demirkaya, MD, MSc, FAVOR, Gulhane Military Medical Faculty; C. Saglam, MD, FAVOR, Gulhane Military Medical Facult

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http://dx.doi.org/10.3899/jrheum.141249DOI Listing
January 2016

What is the diagnosis?

Med Educ 2014 Nov;48(11):1114-5

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http://dx.doi.org/10.1111/medu.12593DOI Listing
November 2014

Unprenylated RhoA contributes to IL-1β hypersecretion in mevalonate kinase deficiency model through stimulation of Rac1 activity.

J Biol Chem 2014 Oct 8;289(40):27757-65. Epub 2014 Aug 8.

From Department of Pediatric Immunology and Infectious Diseases, University Medical Center Utrecht, Wilhelmina Children's Hospital, 3584 EA, Utrecht, the Netherlands and

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http://dx.doi.org/10.1074/jbc.M114.571810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183811PMC
October 2014

Treatment of hereditary autoinflammatory diseases.

Curr Opin Rheumatol 2014 May;26(3):252-8

aDepartment of Pediatric Rheumatology bDepartment of General Pediatrics, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://pdfs.journals.lww.com/co-rheumatology/2014/05000/Trea
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http://dx.doi.org/10.1097/BOR.0000000000000059DOI Listing
May 2014

Defects in mitochondrial clearance predispose human monocytes to interleukin-1β hypersecretion.

J Biol Chem 2014 Feb 19;289(8):5000-12. Epub 2013 Dec 19.

From the Department of Pediatric Immunology and Infectious Diseases, University Medical Center Utrecht, Wilhelmina Children's Hospital, 3584 EA Utrecht, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M113.536920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931060PMC
February 2014

[Familial Mediterranean fever: not to be missed].

Ned Tijdschr Geneeskd 2013 ;157(18):A5784

Universitair Medisch Centrum Utrecht, afd. Algemene Pediatrie, Utrecht, the Netherlands.

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July 2013

Mevalonate kinase deficiency, a metabolic autoinflammatory disease.

Clin Immunol 2013 Jun 4;147(3):197-206. Epub 2012 Oct 4.

Center for Cellular and Molecular Intervention, Division of Pediatrics, University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.clim.2012.09.011DOI Listing
June 2013

Mevalonate kinase deficiency: disclosing the role of mevalonate pathway modulation in inflammation.

Curr Pharm Des 2012 ;18(35):5746-52

Institute for Maternal and Child Health – IRCCS “Burlo Garofolo” – Trieste, Italy.

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http://dx.doi.org/10.2174/138161212803530835DOI Listing
May 2013

Inflammasomes and viruses: cellular defence versus viral offence.

J Gen Virol 2012 Oct 27;93(Pt 10):2063-75. Epub 2012 Jun 27.

Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1099/vir.0.042978-0DOI Listing
October 2012

The Eurofever Project: towards better care for autoinflammatory diseases.

Eur J Pediatr 2011 Apr 1;170(4):445-52. Epub 2011 Mar 1.

Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

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http://link.springer.com/content/pdf/10.1007/s00431-011-1411
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http://link.springer.com/10.1007/s00431-011-1411-z
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http://dx.doi.org/10.1007/s00431-011-1411-zDOI Listing
April 2011

[DIRA: life-threatening but treatable inherited inflammatory disease].

Ned Tijdschr Geneeskd 2010 ;154:A1601

Universitair Medisch Centrum Utrecht, Afd. Kindergeneeskunde, The Netherlands.

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June 2010

Hyperimmunoglobulin D syndrome in childhood.

Curr Rheumatol Rep 2010 Apr;12(2):101-7

Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s11926-010-0086-1DOI Listing
April 2010

HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation.

Blood 2008 Nov 6;112(9):3563-73. Epub 2008 Aug 6.

Department of General Pediatrics, University Medical Centre, Utrecht, The Netherlands.

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http://dx.doi.org/10.1182/blood-2008-03-144667DOI Listing
November 2008

Long-term follow-up, clinical features, and quality of life in a series of 103 patients with hyperimmunoglobulinemia D syndrome.

Medicine (Baltimore) 2008 Nov;87(6):301-10

Department of General Internal Medicine, Radboud University Nijmegen, Medical Centre, Nijmegen, the Netherlands.

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https://insights.ovid.com/crossref?an=00005792-200811000-000
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http://dx.doi.org/10.1097/MD.0b013e318190cfb7DOI Listing
November 2008

Growth of analytical thinking skills over time as measured with the MATCH test.

Med Educ 2008 Oct;42(10):1037-43

Department of Paediatrics, Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2923.2008.03152.xDOI Listing
October 2008

Statin synergizes with LPS to induce IL-1beta release by THP-1 cells through activation of caspase-1.

Mol Immunol 2008 Apr 1;45(8):2158-65. Epub 2008 Feb 1.

Department of General Pediatrics, Division of Pediatrics, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2007.12.008DOI Listing
April 2008

Glucocorticoid-associated Bradycardia.

J Pediatr Hematol Oncol 2008 Feb;30(2):172-5

Utrecht University Medical School, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/MPH.0b013e31815dcfebDOI Listing
February 2008

A role for geranylgeranylation in interleukin-1beta secretion.

Arthritis Rheum 2006 Nov;54(11):3690-5

Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/art.22194DOI Listing
November 2006

Temperature dependence of mutant mevalonate kinase activity as a pathogenic factor in hyper-IgD and periodic fever syndrome.

Hum Mol Genet 2002 Dec;11(25):3115-24

Departments of Paediatrics/Emma Children's Hospital and Clinical Chemistry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/hmg/11.25.3115DOI Listing
December 2002

Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.

Arthritis Rheum 2002 Oct;46(10):2794-803

Division of Pediatrics, Wilhelmina Children's Hospital, KE.04.133.1, University Medical Center Utrecht, PO Box 85090, 3580 AB Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/art.10550DOI Listing
October 2002

Overt and occult rheumatic diseases: the child with chronic fever.

Best Pract Res Clin Rheumatol 2002 Jul;16(3):443-69

Department of General Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Suite KE.04.133.1, P.O. Box 85090, The Netherlands.

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July 2002