Publications by authors named "Joo-Youn Cho"

169Publications

Metastasis-on-a-chip reveals adipocyte-derived lipids trigger cancer cell migration via HIF-1α activation in cancer cells.

Biomaterials 2020 Dec 21;269:120622. Epub 2020 Dec 21.

Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, South Korea; Department of Physiology, Seoul National University College of Medicine, Seoul, 03080, South Korea; Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, 03080, South Korea. Electronic address:

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December 2020

The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects.

Drug Metab Pharmacokinet 2020 Nov 12;36:100368. Epub 2020 Nov 12.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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November 2020

Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects.

Drug Metab Pharmacokinet 2020 Dec 3;36:100374. Epub 2020 Dec 3.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

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December 2020

Population Pharmacokinetic Analysis of Amikacin for Optimal Pharmacotherapy in Korean Patients with Nontuberculous Mycobacterial Pulmonary Disease.

Antibiotics (Basel) 2020 Nov 6;9(11). Epub 2020 Nov 6.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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November 2020

A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators.

Pharmacogenet Genomics 2020 Nov 6. Epub 2020 Nov 6.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital.

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November 2020

Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A.

Transl Clin Pharmacol 2020 Jun 24;28(2):73-82. Epub 2020 Jun 24.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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June 2020

Probiotic treatment induced change of inflammation related metabolites in IBS-D patients/double-blind, randomized, placebo-controlled trial.

Food Sci Biotechnol 2020 Jun 23;29(6):837-844. Epub 2019 Dec 23.

Department of Gastroenterology, Mediplex Sejong Hospital, 20, Gyeyangmunhwa-ro, Gyeyang-gu, Incheon, 21080 Republic of Korea.

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June 2020

A Comprehensive Proteomic and Phosphoproteomic Analysis of Retinal Pigment Epithelium Reveals Multiple Pathway Alterations in Response to the Inflammatory Stimuli.

Int J Mol Sci 2020 Apr 25;21(9). Epub 2020 Apr 25.

Department of Microbiology and Immunology, and Institute of Endemic Disease, Seoul National University College of Medicine, Chongno-gu, Seoul 03080, Korea.

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April 2020

Mechanism of Chronic Kidney Disease Progression and Novel Biomarkers: A Metabolomic Analysis of Experimental Glomerulonephritis.

Metabolites 2020 Apr 24;10(4). Epub 2020 Apr 24.

Kidney Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.

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April 2020

Pharmacokinetics and pharmacodynamics of a fixed-dose combination of gemigliptin/metformin sustained release 25/500 mg compared to the loose combination in healthy male subjects.

Transl Clin Pharmacol 2020 Mar 30;28(1):43-54. Epub 2020 Mar 30.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.

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March 2020

Complex influences of gut microbiome metabolism on various drug responses.

Transl Clin Pharmacol 2020 Mar 30;28(1):7-16. Epub 2020 Mar 30.

Department of Clinical Pharmacology and Therapeutics, Seoul National University, College of Medicine and Hospital, Seoul 03080, Korea.

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March 2020

External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old.

J Korean Med Sci 2020 03 23;35(11):e70. Epub 2020 Mar 23.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.

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March 2020

Pharmacokinetics and Pharmacodynamics of Ursodeoxycholic Acid in an Overweight Population With Abnormal Liver Function.

Clin Pharmacol Drug Dev 2021 Jan 19;10(1):68-77. Epub 2020 Mar 19.

Clinical Trials Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

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January 2021

Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles.

Sci Rep 2020 02 18;10(1):2860. Epub 2020 Feb 18.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

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February 2020

Impact of Vancomycin-Induced Changes in the Intestinal Microbiota on the Pharmacokinetics of Simvastatin.

Clin Transl Sci 2020 07 29;13(4):752-760. Epub 2020 Mar 29.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.

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July 2020

Gut microorganisms and their metabolites modulate the severity of acute colitis in a tryptophan metabolism-dependent manner.

Eur J Nutr 2020 Dec 13;59(8):3591-3601. Epub 2020 Feb 13.

Department of Food and Nutrition, Seoul National University College of Human Ecology, Seoul, 08826, Korea.

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December 2020

Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model.

Mol Brain 2020 02 7;13(1):17. Epub 2020 Feb 7.

Department of Clinical Pharmacology and Therapeutics, College of Medicine, Seoul National University, 103 Daehakro, Jongro-gu, Seoul, Republic of Korea.

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February 2020

Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects.

Sci Rep 2019 12 19;9(1):19410. Epub 2019 Dec 19.

Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Bundang Hospital, Seongnam, Korea.

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December 2019

Author Correction: Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction.

Sci Rep 2019 Nov 13;9(1):17003. Epub 2019 Nov 13.

Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.

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November 2019