Jong-Hwei S Pang

Jong-Hwei S Pang

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Jong-Hwei S Pang

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The anti-angiogenic effect of tryptanthrin is mediated by the inhibition of apelin promoter activity and shortened mRNA half-life in human vascular endothelial cells.

Phytomedicine 2019 May 26;58:152879. Epub 2019 Feb 26.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Taoyuan, Taiwan, ROC; Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2019.152879DOI Listing
May 2019

Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells.

Cytokine 2019 Apr 24;116:48-60. Epub 2019 Jan 24.

Graduate Institute of Health Industry Technology, Research Center for Chinese Herbal Medicine and Research Center for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2019.01.001DOI Listing
April 2019

Monocytic C-C chemokine receptor 5 expression increases in in vitro intermittent hypoxia condition and in severe obstructive sleep apnea patients.

Sleep Breath 2019 Feb 18. Epub 2019 Feb 18.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.

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http://dx.doi.org/10.1007/s11325-019-01797-4DOI Listing
February 2019

Inhibition of Advanced Glycation End Products Formation Attenuates Cardiac Electrical and Mechanical Remodeling and Vulnerability to Tachyarrhythmias in Diabetic Rats.

J Pharmacol Exp Ther 2019 Jan 31;368(1):66-78. Epub 2018 Oct 31.

Graduate Institute of Clinical Medicinal Sciences, College of Medicine, Chang Gung University (G.-J.C., J.-H.S.P., H.-Y.L.), and Cardiovascular Medicine, Chang Gung Memorial Hospital (G.-J.C., Y.-H.Y., W.-J.C., Y.-S.K.), Tao-Yuan, Taiwan.

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http://jpet.aspetjournals.org/lookup/doi/10.1124/jpet.118.25
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http://dx.doi.org/10.1124/jpet.118.252080DOI Listing
January 2019

Promoted Angiogenesis Associated With Modified MMP-2/TIMP-2 Balance and Activation of VEGF Ligand/Receptors Expression.

Front Pharmacol 2018 21;9:979. Epub 2018 Sep 21.

Department of Laboratory Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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https://www.frontiersin.org/article/10.3389/fphar.2018.00979
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http://dx.doi.org/10.3389/fphar.2018.00979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160574PMC
September 2018

Platelet-Rich Plasma Releasate Promotes Regeneration and Decreases Inflammation and Apoptosis of Injured Skeletal Muscle.

Am J Sports Med 2018 Jul 17;46(8):1980-1986. Epub 2018 May 17.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taoyuan City, Taiwan.

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http://dx.doi.org/10.1177/0363546518771076DOI Listing
July 2018

MART-10, a 1α,25(OH)D Analog, Potently Represses Metastasis of ER Breast Cancer Cells with VEGF-A Overexpression.

Anticancer Res 2018 Jul;38(7):3879-3887

Graduate Institute of Clinical Medical Sciences and Nursing department, College of Medicine, Gung University, Taoyuan, Taiwan, R.O.C.

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http://dx.doi.org/10.21873/anticanres.12672DOI Listing
July 2018

Author Correction: Prostaglandin E1 Attenuates Pulmonary Artery Remodeling by Activating Phosphorylation of CREB and the PTEN Signaling Pathway.

Sci Rep 2018 Jul 24;8(1):11383. Epub 2018 Jul 24.

Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Tao-Yuan, 33353, Taiwan.

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http://dx.doi.org/10.1038/s41598-018-28951-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057883PMC
July 2018

Use of Chinese Herbal Medicine Improves Chemotherapy-Induced Thrombocytopenia among Gynecological Cancer Patients: An Observational Study.

Evid Based Complement Alternat Med 2018 12;2018:4201325. Epub 2018 Jul 12.

Biostatistics Unit, Clinical Trial Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

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http://dx.doi.org/10.1155/2018/4201325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106719PMC
July 2018

Prostanoid EP agonist L-902,688 activates PPARγ and attenuates pulmonary arterial hypertension.

Am J Physiol Lung Cell Mol Physiol 2018 03 16;314(3):L349-L359. Epub 2017 Nov 16.

Department of Respiratory Therapy, Chang-Gung University College of Medicine , Tao-Yuan , Taiwan.

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http://dx.doi.org/10.1152/ajplung.00245.2017DOI Listing
March 2018

Platelet rich plasma promotes skeletal muscle cell migration in association with up-regulation of FAK, paxillin, and F-Actin formation.

J Orthop Res 2017 11 23;35(11):2506-2512. Epub 2017 Mar 23.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taoyuan City, Taiwan.

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http://dx.doi.org/10.1002/jor.23547DOI Listing
November 2017

1α,25(OH)D Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Metastasis After VEGF-A Stimulation.

Anticancer Res 2017 11;37(11):6215-6221

Department of Anatomy - College of Medicine, Chang Gung University, Taoyuan, Taiwan, R.O.C.

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http://dx.doi.org/10.21873/anticanres.12072DOI Listing
November 2017

Prostaglandin E1 Attenuates Pulmonary Artery Remodeling by Activating Phosphorylation of CREB and the PTEN Signaling Pathway.

Sci Rep 2017 08 30;7(1):9974. Epub 2017 Aug 30.

Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Tao-Yuan, 33353, Taiwan.

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http://dx.doi.org/10.1038/s41598-017-09707-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577102PMC
August 2017

Platelet rich plasma releasate promotes proliferation of skeletal muscle cells in association with upregulation of PCNA, cyclins and cyclin dependent kinases.

Platelets 2017 Jul 26;28(5):491-497. Epub 2016 Oct 26.

a Department of Physical Medicine and Rehabilitation , Chang Gung Memorial Hospital at Linkou , Taoyuan City , Taiwan.

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http://dx.doi.org/10.1080/09537104.2016.1227061DOI Listing
July 2017

Gallic Acid Inhibited Matrix Invasion and AP-1/ETS-1-Mediated MMP-1 Transcription in Human Nasopharyngeal Carcinoma Cells.

Int J Mol Sci 2017 Jun 24;18(7). Epub 2017 Jun 24.

Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung 404-02, Taiwan.

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http://dx.doi.org/10.3390/ijms18071354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535847PMC
June 2017

MART-10, a newly synthesized vitamin D analog, represses metastatic potential of head and neck squamous carcinoma cells.

Drug Des Devel Ther 2016 17;10:1995-2002. Epub 2016 Jun 17.

General Surgery Department, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China; Zebrafish Center, Chang Gung Memorial Hospital, Keelung, Taiwan, Republic of China.

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http://dx.doi.org/10.2147/DDDT.S107256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918737PMC
May 2017

Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation.

J Mol Med (Berl) 2017 03 15;95(3):323-333. Epub 2016 Nov 15.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan City, Taiwan, Republic Of China.

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http://dx.doi.org/10.1007/s00109-016-1488-yDOI Listing
March 2017

Davallia bilabiata exhibits anti-angiogenic effect with modified MMP-2/TIMP-2 secretion and inhibited VEGF ligand/receptors expression in vascular endothelial cells.

J Ethnopharmacol 2017 Jan 16;196:213-224. Epub 2016 Dec 16.

Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.12.019DOI Listing
January 2017

Lipocalin 2 (LCN2) is a promising target for cholangiocarcinoma treatment and bile LCN2 level is a potential cholangiocarcinoma diagnostic marker.

Sci Rep 2016 10 26;6:36138. Epub 2016 Oct 26.

General Surgery Department and Liver research center, Chang Gung Memorial Hospital, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, R.O.C.

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http://www.nature.com/articles/srep36138
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http://dx.doi.org/10.1038/srep36138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080596PMC
October 2016

PTEN Insufficiency Increases Breast Cancer Cell Metastasis In Vitro and In Vivo in a Xenograft Zebrafish Model.

Anticancer Res 2016 Aug;36(8):3997-4005

Department of Anatomy, College of Medicine, Chang Gung University, Taoyuan, Taiwan, R.O.C. Department of Urology, Chang Gung University, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.

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August 2016

1α,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Growth Through Induction of G0/G1 Cell-cycle Arrest and Apoptosis.

Anticancer Res 2016 Jul;36(7):3307-13

Department of Urology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, R.O.C. Department of Anatomy, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, R.O.C.

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July 2016

Increased MCP-1 gene expression in monocytes of severe OSA patients and under intermittent hypoxia.

Sleep Breath 2016 Mar 9;20(1):425-33. Epub 2015 Sep 9.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1007/s11325-015-1252-5DOI Listing
March 2016

Prevention of Simvastatin-Induced Inhibition of Tendon Cell Proliferation and Cell Cycle Progression by Geranylgeranyl Pyrophosphate.

Toxicol Sci 2016 Feb 16;149(2):326-34. Epub 2015 Nov 16.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan City, Taiwan

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http://dx.doi.org/10.1093/toxsci/kfv239DOI Listing
February 2016

The Anti-Atherosclerotic Effect of Naringin Is Associated with Reduced Expressions of Cell Adhesion Molecules and Chemokines through NF-κB Pathway.

Molecules 2016 Feb 5;21(2). Epub 2016 Feb 5.

Department of Chinese Medicine and Mitochondrial Research Unit, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Da-Pei Road, Niao-Sung District, Kaohsiung 83301, Taiwan.

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http://www.mdpi.com/1420-3049/21/2/195
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http://dx.doi.org/10.3390/molecules21020195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274007PMC
February 2016

MART-10, the new brand of 1α,25(OH)2D3 analog, is a potent anti-angiogenic agent in vivo and in vitro.

J Steroid Biochem Mol Biol 2016 Jan 15;155(Pt A):26-34. Epub 2015 Sep 15.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, ROC.

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https://linkinghub.elsevier.com/retrieve/pii/S09600760153008
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http://dx.doi.org/10.1016/j.jsbmb.2015.09.022DOI Listing
January 2016

MART-10, the vitamin D analog, is a potent drug to inhibit anaplastic thyroid cancer cell metastatic potential.

Cancer Lett 2015 Dec 14;369(1):76-85. Epub 2015 Aug 14.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835150047
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http://dx.doi.org/10.1016/j.canlet.2015.07.024DOI Listing
December 2015

Indigo naturalis and its component tryptanthrin exert anti-angiogenic effect by arresting cell cycle and inhibiting Akt and FAK signaling in human vascular endothelial cells.

J Ethnopharmacol 2015 Nov 1;174:474-81. Epub 2015 Sep 1.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2015.08.050DOI Listing
November 2015

Promoting Diabetic Wound Therapy Using Biodegradable rhPDGF-Loaded Nanofibrous Membranes: CONSORT-Compliant Article.

Medicine (Baltimore) 2015 Nov;94(47):e1873

From the Division of Cardiology, Department of Internal Medicine (C-HL, S-HC, W-JC, K-CH, CC-C, P-CC), Department of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital-Linkou, Chang Gung University College of Medicine (K-SL), Department of Mechanical Engineering (S-JL), Graduate Institute of Clinical Medical Sciences, Chang Gung University (J-HSP), Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University and Chang Gung Memorial Hospital, Tao-Yuan (J-HJ), Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan (Y-TC), and Shui-Mu Foundation of Chemistry, National Tsing Hua University, Hsinchu, Taiwan (F-SW).

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http://dx.doi.org/10.1097/MD.0000000000001873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058951PMC
November 2015

Davallia bilabiata inhibits TNF-α-induced adhesion molecules and chemokines by suppressing IKK/NF-kappa B pathway in vascular endothelial cells.

Am J Chin Med 2014 ;42(6):1411-29

Chinese Herbal Pharmacy, Chang Gung Memorial Hospital, Chang Gung University of Science and Technology, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1142/S0192415X1450089XDOI Listing
August 2015

Increased sulfatase 1 gene expression in degenerative intervertebral disc cells.

J Orthop Res 2015 Mar 2;33(3):312-7. Epub 2014 Dec 2.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan; Department of Orthopaedic Surgery, Spine Section, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

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http://dx.doi.org/10.1002/jor.22766DOI Listing
March 2015

Augmentation of diabetic wound healing and enhancement of collagen content using nanofibrous glucophage-loaded collagen/PLGA scaffold membranes.

J Colloid Interface Sci 2015 Feb 24;439:88-97. Epub 2014 Oct 24.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung University and Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1016/j.jcis.2014.10.028DOI Listing
February 2015

The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells.

Cancer Lett 2014 Nov 19;354(2):235-44. Epub 2014 Aug 19.

Department of Anatomy, College of Medicine, Chang Gung University, Kwei-Shan Taoyuan, 333, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.08.019DOI Listing
November 2014

Low-level laser irradiation stimulates tenocyte proliferation in association with increased NO synthesis and upregulation of PCNA and cyclins.

Lasers Med Sci 2014 Jul 9;29(4):1377-84. Epub 2014 Feb 9.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Gueishan Township, Taoyuan County, Taiwan.

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http://link.springer.com/10.1007/s10103-014-1528-1
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http://dx.doi.org/10.1007/s10103-014-1528-1DOI Listing
July 2014

Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma.

PLoS One 2013 26;8(7):e69928. Epub 2013 Jul 26.

General Surgery Department, Chang Gung Memorial Hospital, Kwei-Shan, Taoyuan, Taiwan, ROC.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069928PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724720PMC
April 2014

Enhancement of diabetic wound repair using biodegradable nanofibrous metformin-eluting membranes: in vitro and in vivo.

ACS Appl Mater Interfaces 2014 Mar 6;6(6):3979-86. Epub 2014 Mar 6.

Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital-Linkou, Chang Gung University College of Medicine , Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1021/am405329gDOI Listing
March 2014

Advanced glycation end products in degenerative nucleus pulposus with diabetes.

J Orthop Res 2014 Feb 22;32(2):238-44. Epub 2013 Oct 22.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, 259 Wenhwa 1st Road, Taoyuan, Taiwan, R.O.C.; Department of Orthopaedic Surgery, Spine Section, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.

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http://dx.doi.org/10.1002/jor.22508DOI Listing
February 2014

The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-α-induced VCAM-1, ICAM-1 and CX3CL1 expression.

Phytomedicine 2014 Feb 21;21(3):207-16. Epub 2013 Oct 21.

Department of Chinese Medicine and Mitochondrial Research Unit, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2013.09.012DOI Listing
February 2014

MART-10, a less calcemic vitamin D analog, is more potent than 1α,25-dihydroxyvitamin D3 in inhibiting the metastatic potential of MCF-7 breast cancer cells in vitro.

J Steroid Biochem Mol Biol 2014 Jan 12;139:54-60. Epub 2013 Oct 12.

General Surgery Department, Chang Gung Memorial Hospital, 222, Mai-Chin Road, Keelung, Taiwan, ROC; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.jsbmb.2013.10.005DOI Listing
January 2014

MART-10, a novel vitamin D analog, inhibits head and neck squamous carcinoma cells growth through cell cycle arrest at G0/G1 with upregulation of p21 and p27 and downregulation of telomerase.

J Steroid Biochem Mol Biol 2013 Nov 14;138:427-34. Epub 2013 Sep 14.

General Surgery Department, Chang Gung Memorial Hospital, 222, Mai-Chin Road, Keelung, Taiwan, ROC; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.jsbmb.2013.09.002DOI Listing
November 2013

Increased matrix metalloproteinases-9 after sleep in plasma and in monocytes of obstructive sleep apnea patients.

Life Sci 2013 Aug 20;93(5-6):220-5. Epub 2013 Jun 20.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.lfs.2013.06.009DOI Listing
August 2013

High glucose concentration up-regulates the expression of matrix metalloproteinase-9 and -13 in tendon cells.

BMC Musculoskelet Disord 2013 Aug 27;14:255. Epub 2013 Aug 27.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.

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http://dx.doi.org/10.1186/1471-2474-14-255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765930PMC
August 2013

MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D(3) in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells.

Evid Based Complement Alternat Med 2012 11;2012:310872. Epub 2012 Dec 11.

General Surgery Department, Chang Gung Memorial Hospital, 222 Mai-Chin Road, Keelung 204, Taiwan ; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan.

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http://dx.doi.org/10.1155/2012/310872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530235PMC
March 2013

Increased periostin gene expression in degenerative intervertebral disc cells.

Spine J 2013 Mar 27;13(3):289-98. Epub 2013 Feb 27.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, 259 Wen-Hwa 1st Rd, Kwei-Shan, Tao-Yuan, Taiwan, Republic of China.

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http://dx.doi.org/10.1016/j.spinee.2013.01.040DOI Listing
March 2013

Aging is associated with increased activities of matrix metalloproteinase-2 and -9 in tenocytes.

BMC Musculoskelet Disord 2013 Jan 2;14. Epub 2013 Jan 2.

Departement of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taiwan.

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http://dx.doi.org/10.1186/1471-2474-14-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621429PMC
January 2013

Low-level laser irradiation stimulates tenocyte migration with up-regulation of dynamin II expression.

PLoS One 2012 30;7(5):e38235. Epub 2012 May 30.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Taoyuan County, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038235PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364209PMC
October 2012

Ellagic Acid, the Active Compound of Phyllanthus urinaria, Exerts In Vivo Anti-Angiogenic Effect and Inhibits MMP-2 Activity.

Evid Based Complement Alternat Med 2011 11;2011:215035. Epub 2011 Jan 11.

Department of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan.

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http://www.hindawi.com/journals/ecam/2011/215035/
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http://dx.doi.org/10.1093/ecam/nep207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095481PMC
August 2012

Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes.

J Dermatol Sci 2012 Aug 2;67(2):140-6. Epub 2012 Jun 2.

Graduate Institute of Biomedical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.jdermsci.2012.05.008DOI Listing
August 2012

The effect of aging on migration, proliferation, and collagen expression of tenocytes in response to ciprofloxacin.

J Orthop Res 2012 May 21;30(5):764-8. Epub 2011 Oct 21.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, College of Medicine, Chang Gung University, Taiwan.

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http://dx.doi.org/10.1002/jor.21576DOI Listing
May 2012

In vivo and in vitro inhibitory effects of a traditional Chinese formulation on LPS-stimulated leukocyte-endothelial cell adhesion and VCAM-1 gene expression.

J Ethnopharmacol 2012 Mar 9;140(1):55-63. Epub 2011 Dec 9.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.jep.2011.12.002DOI Listing
March 2012

Anti-angiogenic effect of Tanshinone IIA involves inhibition of matrix invasion and modification of MMP-2/TIMP-2 secretion in vascular endothelial cells.

Cancer Lett 2011 Nov 5;310(2):198-206. Epub 2011 Jul 5.

Department of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.canlet.2011.06.031DOI Listing
November 2011

Cilostazol inhibits matrix invasion and modulates the gene expressions of MMP-9 and TIMP-1 in PMA-differentiated THP-1 cells.

Eur J Pharmacol 2011 Nov 12;670(2-3):419-26. Epub 2011 Sep 12.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan, Taiwan, ROC.

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http://linkinghub.elsevier.com/retrieve/pii/S001429991100950
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http://dx.doi.org/10.1016/j.ejphar.2011.08.040DOI Listing
November 2011

Decreased proliferation of aging tenocytes is associated with down-regulation of cellular senescence-inhibited gene and up-regulation of p27.

J Orthop Res 2011 Oct 30;29(10):1598-603. Epub 2011 Mar 30.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taiwan.

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http://dx.doi.org/10.1002/jor.21418DOI Listing
October 2011

Cilostazol reduces MCP-1-induced chemotaxis and adhesion of THP-1 monocytes by inhibiting CCR2 gene expression.

Biochem Biophys Res Commun 2011 Jul 2;411(2):402-8. Epub 2011 Jul 2.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.bbrc.2011.06.163DOI Listing
July 2011

Zinc-chelation contributes to the anti-angiogenic effect of ellagic acid on inhibiting MMP-2 activity, cell migration and tube formation.

PLoS One 2011 May 4;6(5):e18986. Epub 2011 May 4.

Department of Chinese Medicine, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087719PMC
May 2011

Anti-cancer effects of Phyllanthus urinaria and relevant mechanisms.

Chang Gung Med J 2010 Sep-Oct;33(5):477-87

Department of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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February 2011

Procalcitonin as a biomarker for bacterial infections in patients with liver cirrhosis in the emergency department.

Acad Emerg Med 2011 Feb 28;18(2):121-6. Epub 2011 Jan 28.

Department of Emergency Medicine, Chang-Gung Memorial Hospital, Keelung Branch, Taipei, Taiwan, ROC.

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http://dx.doi.org/10.1111/j.1553-2712.2010.00991.xDOI Listing
February 2011

Ciprofloxacin up-regulates tendon cells to express matrix metalloproteinase-2 with degradation of type I collagen.

J Orthop Res 2011 Jan;29(1):67-73

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, College of Medicine, Chang Gung University, Linkou, Taiwan.

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http://doi.wiley.com/10.1002/jor.21196
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January 2011

Ibuprofen upregulates expressions of matrix metalloproteinase-1, -8, -9, and -13 without affecting expressions of types I and III collagen in tendon cells.

J Orthop Res 2010 Apr;28(4):487-91

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital College of Medicine, Chang Gung University, 5 Fu-Shin Street, Taoyuan County 333, Taiwan.

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http://dx.doi.org/10.1002/jor.21009DOI Listing
April 2010

Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells.

Phytomedicine 2010 Jan 3;17(1):47-54. Epub 2009 Jul 3.

Department of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan.

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http://dx.doi.org/10.1016/j.phymed.2009.06.005DOI Listing
January 2010

Propylthiouracil, independent of its antithyroid effect, promotes vascular smooth muscle cells differentiation via PTEN induction.

Basic Res Cardiol 2010 Jan 25;105(1):19-28. Epub 2009 Jul 25.

First Cardiovascular Division, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Fu-Shin Road no 5, Kwei-Shan, Tao-Yuan, 333, Taiwan.

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http://link.springer.com/10.1007/s00395-009-0045-z
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http://dx.doi.org/10.1007/s00395-009-0045-zDOI Listing
January 2010

Therapeutic ultrasound stimulation of tendon cell migration.

Connect Tissue Res 2008 ;49(5):367-73

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, and College of Medicine, Chang Gung University, Taoyuan, Taiwan.

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http://dx.doi.org/10.1080/03008200802325359DOI Listing
August 2009

Thrombin regulates matrix metalloproteinase-9 expression in human monocytes.

Biochem Biophys Res Commun 2009 Jul 18;385(2):241-6. Epub 2009 May 18.

The First Cardiovascular Division, Chang-Gung University, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1016/j.bbrc.2009.05.049DOI Listing
July 2009

Intense pulsed light effects on the expression of extracellular matrix proteins and transforming growth factor beta-1 in skin dermal fibroblasts cultured within contracted collagen lattices.

Dermatol Surg 2009 May 30;35(5):816-25. Epub 2009 Mar 30.

Graduate Institute of Clinical Medical Sciences, Chang Gung Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1111/j.1524-4725.2009.01138.xDOI Listing
May 2009

Ciprofloxacin-mediated inhibition of tenocyte migration and down-regulation of focal adhesion kinase phosphorylation.

Eur J Pharmacol 2009 Apr 14;607(1-3):23-6. Epub 2009 Feb 14.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Taiwan.

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http://dx.doi.org/10.1016/j.ejphar.2009.02.006DOI Listing
April 2009

Phyllanthus urinaria increases apoptosis and reduces telomerase activity in human nasopharyngeal carcinoma cells.

Forsch Komplementmed 2009 Feb 6;16(1):34-40. Epub 2009 Feb 6.

Department of Chinese Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung Institute of Technology, Taiwan, Republic of China.

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http://dx.doi.org/10.1159/000194154DOI Listing
February 2009

Propylthiouracil, independent of its antithyroid effect, decreases VSMC collagen expression.

Basic Res Cardiol 2009 Jan 15;104(1):60-8. Epub 2008 Sep 15.

First Cardiovascular Division, Chang Gung Memorial Hospital, Fu-Shin Road no. 5, Kwei-Shan, Tao-Yuan, Taiwan 333.

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http://dx.doi.org/10.1007/s00395-008-0746-8DOI Listing
January 2009

Ciprofloxacin-mediated cell proliferation inhibition and G2/M cell cycle arrest in rat tendon cells.

Arthritis Rheum 2008 Jun;58(6):1657-63

Chang Gung Memorial Hospital Department of Physical Medicine and Rehabilitation, Chang Gung University College of Medicine, Taoyuan, Taiwan.

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http://doi.wiley.com/10.1002/art.23518
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June 2008

Propylthiouracil, independent of its antithyroid effect, produces endothelium-dependent vasodilatation through induction of nitric oxide bioactivity.

Atherosclerosis 2008 Jan 18;196(1):383-90. Epub 2006 Dec 18.

First Cardiovascular Division, Department of Cardiology, Chang Gung Memorial Hospital, Fu-Shin Road no. 5, Kwei-Shan, Tao-Yuan 333, Taiwan.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.11.018DOI Listing
January 2008

The pentapeptide KTTKS promoting the expressions of type I collagen and transforming growth factor-beta of tendon cells.

J Orthop Res 2007 Dec;25(12):1629-34

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, 259 Wen-Hwa 1 Road, Kweishan 333, Taoyuan, Taiwan.

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http://dx.doi.org/10.1002/jor.20455DOI Listing
December 2007

Effects of celecoxib on migration, proliferation and collagen expression of tendon cells.

Connect Tissue Res 2007 ;48(1):46-51

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

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http://dx.doi.org/10.1080/03008200601071295DOI Listing
April 2007

Inhibition of melanogenesis in murine B16/F10 melanoma cells by Ligusticum sinensis Oliv.

Am J Chin Med 2006 ;34(3):523-33

Department of Chinese Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan, R.O.C.

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http://www.worldscientific.com/doi/abs/10.1142/S0192415X0600
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December 2006

Anti-tumor and anti-angiogenic effects of Phyllanthus urinaria in mice bearing Lewis lung carcinoma.

Int Immunopharmacol 2006 Jun 30;6(6):870-9. Epub 2006 Jan 30.

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.intimp.2005.12.010DOI Listing
June 2006

Ultrasound stimulation of types I and III collagen expression of tendon cell and upregulation of transforming growth factor beta.

J Orthop Res 2006 Jun;24(6):1310-6

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, 5, Fu-Shin Street, Kweishan, Taoyuan 333, Taiwan.

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http://dx.doi.org/10.1002/jor.20130DOI Listing
June 2006

Ibuprofen inhibition of tendon cell migration and down-regulation of paxillin expression.

J Orthop Res 2006 Mar;24(3):551-8

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Building J, 12F, 5 Fu-Shin Street, Kweishan, Taoyuan 333, Taiwan.

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http://dx.doi.org/10.1002/jor.20069DOI Listing
March 2006

Linear allele-specific long-range amplification: a novel method of long-range molecular haplotyping.

Hum Mutat 2005 Oct;26(4):393-4

Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1002/humu.9369DOI Listing
October 2005

Thrombosed arteriovenous fistula for hemodialysis access is characterized by a marked inflammatory activity.

Kidney Int 2005 Sep;68(3):1312-9

First Cardiovascular Division, Chang Gung Memorial Hospital, Chang Gung University, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00529.xDOI Listing
September 2005

Ultrasound stimulation of tendon cell proliferation and upregulation of proliferating cell nuclear antigen.

J Orthop Res 2005 Jul 26;23(4):970-6. Epub 2005 Jan 26.

Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Building J, 12F, 5 Fu-Shing Street, Kweishan, Taoyuan 333, Taiwan.

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http://doi.wiley.com/10.1016/j.orthres.2004.11.013
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July 2005

Aqueous extract of Phyllanthus urinaria induces apoptosis in human cancer cells.

Am J Chin Med 2004 ;32(2):175-83

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan, Taiwan.

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http://www.worldscientific.com/doi/abs/10.1142/S0192415X0400
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http://dx.doi.org/10.1142/S0192415X04001849DOI Listing
November 2004

Phyllanthus urinaria induces the Fas receptor/ligand expression and ceramide-mediated apoptosis in HL-60 cells.

Life Sci 2004 Jun;75(3):339-51

Chinese Herbal Pharmacy, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan, ROC.

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http://dx.doi.org/10.1016/j.lfs.2003.12.013DOI Listing
June 2004

Ibuprofen inhibition of tendon cell proliferation and upregulation of the cyclin kinase inhibitor p21CIP1.

J Orthop Res 2004 May;22(3):586-91

Department of Physical Medicine and Rehabilitation, Graduate Institute of Clinical Medical Sciences, Chang Gung Memorial Hospital, Chang Gung University, Building J, 12F, 5 Fu-Shing Street, Kweishan, Taoyuan 333, Taiwan.

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http://dx.doi.org/10.1016/j.orthres.2003.10.014DOI Listing
May 2004

Percutaneous transvenous mitral valvulotomy normalizes elevated circulating levels of tumor necrosis factor-alpha and interleukin-6 in mitral stenosis with heart failure.

Am J Cardiol 2003 Apr;91(8):1018-20, A8

First Cardiovascular Division, Chang Gung Memorial Hospital, Fu-Shin Road no. 5, Kwei-Shan, Tao-Yuan, Taipei, Taiwan 333.

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April 2003

Inhibition of tendon cell migration by dexamethasone is correlated with reduced alpha-smooth muscle actin gene expression: a potential mechanism of delayed tendon healing.

J Orthop Res 2003 Mar;21(2):265-71

Department of Physical Medicine and Rehabilitation, Graduate Institute of Clinical Medical Sciences, Chang Gung Memorial Hospital, Chang Gung University, Building J, 12F, 5 Fu-Shin Street, Gueishan, Taoyuan, Taiwan.

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http://dx.doi.org/10.1016/S0736-0266(02)00151-1DOI Listing
March 2003

Phyllanthus urinaria triggers the apoptosis and Bcl-2 down-regulation in Lewis lung carcinoma cells.

Life Sci 2003 Feb;72(15):1705-16

Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan, Taiwan, ROC.

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February 2003

Telomerase expression in benign and malignant skin neoplasms: comparison of three major subunits.

J Formos Med Assoc 2002 Aug;101(8):593-7

Department of Dermatology, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.

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August 2002