Jonathon Leipsic

Jonathon Leipsic

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Jonathon Leipsic

Jonathon Leipsic

Publications by authors named "Jonathon Leipsic"

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100Publications

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Correlation of FFR-derived from CT and stress perfusion CMR with invasive FFR in intermediate-grade coronary artery stenosis.

Int J Cardiovasc Imaging 2018 Oct 3. Epub 2018 Oct 3.

Centre Hospitalier de Luxembourg, 4, Rue Ernest Barble L-1120, LU 1210, Luxembourg City, Luxembourg.

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October 2018

Left ventricular outflow obstruction predicts increase in systolic pressure gradients and blood residence time after transcatheter mitral valve replacement.

Sci Rep 2018 Oct 19;8(1):15540. Epub 2018 Oct 19.

Department of Biomedical Engineering, School of Imaging Sciences & Biomedical Engineering, King's College London, King's Health Partners, St Thomas Hospital, London, SE1 7EH, UK.

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October 2018

Phenotyping COPD exacerbations using imaging and blood-based biomarkers.

Int J Chron Obstruct Pulmon Dis 2018 8;13:217-229. Epub 2018 Jan 8.

Centre for Heart Lung Innovation, James Hogg Research Centre, St Paul's Hospital, Vancouver, BC, Canada.

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September 2018

Mitral Valve Imaging with CT: Relationship with Transcatheter Mitral Valve Interventions.

Radiology 2018 09 31;288(3):638-655. Epub 2018 Jul 31.

From the UBC Department of Medical Imaging, Centre for Heart Valve Innovation, St Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6 (J.R.W.M., P.B., J.L.); Department of Cardiology, Concord Hospital, The University of Sydney, Sydney, Australia (C.N.); and Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands (V.D., J.J.B.).

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September 2018

Development of a congenital cardiovascular computed tomography imaging registry: Rationale and implementation.

J Cardiovasc Comput Tomogr 2018 May - Jun;12(3):263-266. Epub 2018 Mar 16.

Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, Minneapolis, MN, USA.

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August 2018

CAC-DRS: Coronary Artery Calcium Data and Reporting System. An expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT).

J Cardiovasc Comput Tomogr 2018 May - Jun;12(3):185-191. Epub 2018 Mar 30.

Department of Medicine, Emory University School of Medicine, Atlanta, GA, United States.

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August 2018

Impact of Non-obstructive left main disease on the progression of coronary artery disease: A PARADIGM substudy.

J Cardiovasc Comput Tomogr 2018 May - Jun;12(3):231-237. Epub 2018 May 19.

St. Paul's Hospital & University of British Columbia, Department of Radiology, Vancouver, British Columbia, Canada; Centre for Heart Lung Innovation, University of British Columbia & St. Paul's Hospital, Vancouver, British Columbia, Canada. Electronic address:

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August 2018

Fluoroscopic Anatomy of Right-Sided Heart Structures for Transcatheter Interventions.

JACC Cardiovasc Interv 2018 Aug;11(16):1614-1625

Department of Medicine, Division of Cardiology, McGill University Health Centre, Montreal, Quebec, Canada; Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address:

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August 2018

Hypertrophic Cardiomyopathy (HCM): New insights into Coronary artery remodelling and ischemia from FFR.

J Cardiovasc Comput Tomogr 2018 Aug 15. Epub 2018 Aug 15.

Department of Radiology, St Paul's Hospital and University of British Columbia, Vancouver, Canada; Heart Flow Inc, Redwood City, CA, USA; Division of Cardiology, Department of Medicine, University of British Columbia, Vancouver, Canada. Electronic address:

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August 2018

Is it time to move from treating risk factors of the disease to treating the disease?

Eur Heart J 2018 Jul;39(25):2409-2411

St Paul's Hospital & University of British Columbia, Vancouver, British Columbia, Vancouver, Canada.

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July 2018

Cardiac Fibroma in an Adult AIRP Best Cases in Radiologic-Pathologic Correlation.

Radiographics 2018 Jul-Aug;38(4):1022-2026

From the Department of Radiology (G.L.G., J.A.L., S.L.S.), Centre for Heart Lung Innovation (J.A.L., S.L.S., M.A.S.), and Department of Pathology (M.A.S.), St Paul's Hospital and University of British Columbia, Vancouver, BC, Canada; and Division of Cardiology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada (J.A.L.).

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July 2018

Coronary CT Angiography to Guide Treatment Decision Making: Lessons From the SYNTAX II Trial.

J Am Coll Cardiol 2018 Jun 22;71(24):2770-2772. Epub 2018 May 22.

Department of Cardiology, Friedrich-Alexander-University, Erlangen-Nürnberg, Germany.

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June 2018

A Novel Method of Estimating Small Airway Disease Using Inspiratory-to-Expiratory Computed Tomography.

Respiration 2017 23;94(4):336-345. Epub 2017 Aug 23.

UBC Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, Canada.

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May 2018

Blooming Artifact Reduction in Coronary Artery Calcification by A New De-blooming Algorithm: Initial Study.

Sci Rep 2018 May 2;8(1):6945. Epub 2018 May 2.

Department of Radiology, St Paul's Hospital and University of British Columbia, Vancouver, BC, V6Z 1Y6, Canada.

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May 2018

Imaging Needs in Novel Transcatheter Tricuspid Valve Interventions.

JACC Cardiovasc Imaging 2018 May;11(5):736-754

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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May 2018

Prevalence and impact of scan-related anxiety during coronary CT angiography: A prospective cohort study of 366 patients.

J Cardiovasc Comput Tomogr 2018 Sep - Oct;12(5):364-371. Epub 2018 May 4.

Radiology Department, St Paul's Hospital, St. Paul's Hospital, 1081 Burrard St., Vancouver, British Columbia, V6Z 1Y6 Canada.

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May 2018

Update on Cardiovascular Applications of Multienergy CT.

Radiographics 2017 Nov-Dec;37(7):1955-1974

From the Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio (K.K.); Philips Healthcare, Cleveland, Ohio (S.H.); Department of Radiology, Cardiothoracic Imaging Division, University of Texas Southwestern Medical Center, E6.120 B, Mail Code 9316, 5323 Harry Hines Blvd, Dallas, TX 75390-8896 (S.A., P.R.); Department of Radiology, University of British Columbia, Vancouver, Canada (J.A.L.); and Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC (M.H.A., U.J.S.).

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April 2018

CT Fractional Flow Reserve for Stable Coronary Artery Disease: The Ongoing Journey.

Radiology 2018 04;287(1):85-86

From the Department of Radiology and Centre for Heart Lung Innovation, St. Paul's Hospital & University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6 (J.A.L.); and Department of Radiology, Duke University Medical Center, Durham, NC (L.H.K.).

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April 2018

The contribution of thoracic vertebral deformity and arthropathy to trunk pain in patients with chronic obstructive pulmonary disease (COPD).

Respir Med 2018 04 3;137:115-122. Epub 2018 Mar 3.

Department of Physical Therapy, University of Toronto, Toronto Rehabilitation Institute, Interdivisional Department of Critical Care Medicine, Toronto, Canada.

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April 2018

Role of MDCT Imaging in Planning Mitral Valve Intervention.

Curr Cardiol Rep 2018 Mar 6;20(3):16. Epub 2018 Mar 6.

Department of Radiology, St Paul's Hospital and University of British Columbia, Vancouver, Canada.

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March 2018

Prospective Comparison of Standard- Versus Low-Radiation-Dose CT Enterography for the Quantitative Assessment of Crohn Disease.

AJR Am J Roentgenol 2018 Feb 20;210(2):W54-W62. Epub 2017 Dec 20.

1 Department of Medicine, Division of Gastroenterology, University of British Columbia, 770 - 1190 Hornby St, Vancouver, BC V6Z 2K5, Canada.

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February 2018

The Authors Reply.

JACC Cardiovasc Imaging 2018 Feb;11(2 Pt 1):285-286

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February 2018

It's in the Field of View! Coronary Artery Analysis on Chest Computed Tomographic Angiography.

Circ Res 2018 Feb;122(3):402-404

From the Icahn School of Medicine at Mount Sinai, New York (H.S.H., J.N.); and Department of Medicine and Radiology, University of British Columbia, Vancouver, Canada (J.L.).

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February 2018

Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study.

Am J Respir Crit Care Med 2018 Jan;197(1):56-65

1 The University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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January 2018

Noninvasive FFR Derived From Coronary CT Angiography: Management and Outcomes in the PROMISE Trial.

JACC Cardiovasc Imaging 2017 Nov 12;10(11):1350-1358. Epub 2017 Apr 12.

Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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November 2017

Structured reporting platform improves CAD-RADS assessment.

J Cardiovasc Comput Tomogr 2017 Nov 18;11(6):449-454. Epub 2017 Sep 18.

MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Varosmajor Str. 68, Budapest, Hungary. Electronic address:

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November 2017

Coronary lumen volume to myocardial mass ratio in primary microvascular angina.

J Cardiovasc Comput Tomogr 2017 Nov 22;11(6):423-428. Epub 2017 Sep 22.

Department of Radiology, St Paul's Hospital and University of British Columbia, Vancouver, Canada; Centre for Heart Lung Innovation, St Paul's Hospital and University of British Columbia, Vancouver, Canada.

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November 2017

Fractional flow reserve computed tomography in the evaluation of coronary artery disease.

Cardiovasc Diagn Ther 2017 Oct;7(5):463-474

St Paul's Hospital, Vancouver, Canada.

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October 2017

Multimodality Imaging for Planning and Follow-up of Transcatheter Aortic Valve Replacement.

Can J Cardiol 2017 09 4;33(9):1110-1123. Epub 2017 Apr 4.

Department of Radiology, Centre for Heart Valve Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada. Electronic address:

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September 2017

Coronary CT Angiography Derived Fractional Flow Reserve: The Game Changer in Noninvasive Testing.

Curr Cardiol Rep 2017 09 22;19(11):112. Epub 2017 Sep 22.

Department of Radiology and Medicine, St. Paul´s Hospital, University of British Columbia, Vancouver, Canada.

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September 2017

Imaging for structural heart procedures: focus on computed tomography.

EuroIntervention 2017 Sep;13(AA):AA85-AA96

Department of Radiology, St. Paul's Hospital and University of British Columbia, Vancouver, Canada.

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September 2017

Relationship between changes in blood pressure and left ventricular mass over 1 year in end-stage renal disease.

J Hypertens 2017 Aug;35(8):1709-1716

aTerrence Donnelly Heart Centre, St Michael's Hospital bUniversity of Toronto cDivision of Nephrology, St Michael's Hospital and Li Ka Shing Knowledge Institute of St Michael's Hospital dDepartment of Medical Imaging, St Michael's Hospital, Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario eDepartment of Radiology and Medicine fDivision of Nephrology, St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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August 2017

C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations.

PLoS One 2017 22;12(3):e0174063. Epub 2017 Mar 22.

Centre for Heart Lung Innovation, James Hogg Research Centre, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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August 2017

Relationship of Hypertension to Coronary Atherosclerosis and Cardiac Events in Patients With Coronary Computed Tomographic Angiography.

Hypertension 2017 08 12;70(2):293-299. Epub 2017 Jun 12.

From the Los Angeles BioMedical Research Institute at Harbor UCLA Medical Center, Torrance, CA (R.N., M.J.B.); Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA (R.N., H.G., D.S.B.); Department of Radiology, Dalio Institute of Cardiovascular Imaging, NewYork-Presbyterian Hospital and Weill Cornell Medicine (L.B., E.J., N.H., M.G., F.Y.L., J.K.M.); Department of Medicine, University of Erlangen, Germany (S.A.); King Saudbin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King AbdulAziz Cardiac Center, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia (M.A.-M.); Department of Radiology, Montreal Heart Institute, Quebec, Canada (F.C., E.M.); Department of Radiology, Erasmus University Medical Center, Rotterdam, The Netherlands (F.C., E.M.); Tennessee Heart and Vascular Institute, Hendersonville (T.Q.C.); Division of Cardiology, Severance Cardiovascular Hospital and Severance Biomedical Science Institute, Yonsei University College of Medicine, Yonsei University Health System, Seoul, South Korea (H.-J.C.); William Beaumont Hospital, Royal Oaks, MI (K.C., G.R.); Department of Medicine and Radiology, University of Ottawa, Ontario, Canada (B.J.W.C.); Capitol Cardiology Associates, Albany, New York (A.D.); Department of Radiology and Nuclear Medicine, German Heart Center Munich, Germany (M.H.); Medizinische Klinik und Poliklinik I, Ludwig-Maximilians-Universität München, Germany (J.H.); Baptist Cardiac and Vascular Institute, Miami, FL (R.C.); Department of Radiology, Medical University of Innsbruck, Austria (G.F.); Department of Medicine and Radiology, Seoul National University Hospital, South Korea (Y.-J.K.); Department of Medicine and Radiology, University of British Columbia, Vancouver, Canada (J.L.); Department of Nuclear Cardiology, Cardiovascular Center, University Hospital, Zurich, Switzerland (P.A.K.); Department of Cardiology, Emory University School of Medicine, Atlanta, GA (L.J.S.); Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD (T.C.V.); Duke Clinical Research Institute, Durham, NC (A.D.); UNICA, Cardiac CT and MRI Unit, Hospital da Luz, Lisbon, Portugal (H.M.); Department of Clinical Sciences and Community Health, University of Milan, Italy (G.P., D.A.); Centro Cardiologico Monzino, IRCCS, Italy (G.P., D.A.); Department of Cardiology at the Lady Davis Carmel Medical Center, The Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (R.R.); and Department of Cardiology, Leiden University Medical Center, HARTZ, The Netherlands (J.B.).

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August 2017

Prognostic Significance of Nonobstructive Left Main Coronary Artery Disease in Women Versus Men: Long-Term Outcomes From the CONFIRM (Coronary CT Angiography Evaluation For Clinical Outcomes: An International Multicenter) Registry.

Circ Cardiovasc Imaging 2017 Aug;10(8)

From the Department of Cardiology, Emory University School of Medicine, Atlanta, GA (J.X.X., P.E., T.V., A.G., P.K.M., W.K., L.J.S.); Department of Cardiology, University of British Columbia, Vancouver, Canada (J.L.); Department of Cardiology, Weill Cornell Medical College and the New York Presbyterian Hospital, NY (B.ó.H., J.K.M.); Department of Cardiology, Barbara Stresiand Women's Heart Center, Cedars-Sinai Medical Center, Los Angeles, CA (C.N.B.M., D.S.B., H.G.); Department of Cardiology, Harbor UCLA Medical Center, Los Angeles, CA (M.J.B.); Department of Cardiology, University of Erlangen, Germany (S.A.); Department of Cardiolog, Tennessee Heart and Vascular Institute, Hendersonville, TN (T.Q.C.); Department of Cardiology, Hospital da Luz, Lisbon, Portugal (H.M.); Department of Cardiology, The Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (R.R.); Department of Cardiology, Henry Ford Hospital, Detroit, MI (M.H.A.-M.); Department of Cardiology, University of Milan, Centro Cardiologico Monzino, IRCCS, Italy (D.A., G.P.); Department of Radiology/Centre de Recherche, Montreal Heart Institute/Universitè de Montreal, Quebec, Canada (F.C., E.M.); Department of Cardiology, William Beaumont Hospital, Royal Oaks, MI (K.C., G.R.); Department of Cardiology, Deutsches Herzzentrum Munchen, Munich, Germany (M.H.); Department of Cardiology, Medizinische Klinik I der Ludwig-Maximilians-Universität München, Munich, Germany (J.H.); Department of Cardiology, Medical University of Innsbruck, Austria (G.F.); Department of Cardiology, University Hospital, Zurich, Switzerland (P.A.K.); Department of Cardiology, Walter Reed Medical Center, Washington, DC (T.C.V); Department of Cardiology, University of Ottawa Heart Institute, Ontario, Canada (B.J.W.C.).

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August 2017

Cardiac CT: a coming of age.

Minerva Cardioangiol 2017 06;65(3):199-200

Department of Medical Imaging, St Paul's Hospital, Vancouver, BC, Canada.

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June 2017

Indexed Aortic Area in Bicuspid Valve Disease: An Important Step Toward a More Personalized Approach to Risk Prediction and Clinical Decision Making.

Circ Cardiovasc Imaging 2017 Jun;10(6):e006593

From the Centre for Heart Lung Innovation, University of British Columbia, Vancouver, Canada (S.L.S., J.A.L.); and University of British Columbia and Department of Radiology, St. Paul's Hospital, Vancouver, Canada (S.L.S., D.T.M., J.A.L.).

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June 2017

Predictive Value of Age- and Sex-Specific Nomograms of Global Plaque Burden on Coronary Computed Tomography Angiography for Major Cardiac Events.

Circ Cardiovasc Imaging 2017 Mar;10(3)

From the Department of Medicine and Radiology, University of British Columbia, Vancouver, Canada (C.N., P.B., J.L.); Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA (D.S.B., H.G.); Department of Cardiology, Mount Sinai Hospital Medical Centre, New York, NY (A.A., J.N.); Division of Cardiology, Emory University School of Medicine, Atlanta, GA (L.J.S.); Department of Cardiology, Concord Hospital and The University of Sydney, New South Wales, Australia (L.K.); Department of Medicine, University of Erlangen, Germany (S.A.); Department of Medicine, Wayne State University, Henry Ford Hospital, Detroit, MI (M.H.A.-M.); Department of Clinical Sciences and Community Health, University of Milan, Centro Cardiologico Monzino, IRCCS Milan, Italy (D.A., G.P.); Department of Medicine, Harbor University of California Los Angeles Medical Center (M.J.B.); Cardiovascular Imaging Unit, Giovanni XXIII Hospital, Monastier, Treviso, Italy (F.C., E.M.); Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands (F.C., E.M.); Tennessee Heart and Vascular Institute, Hendersonville (T.Q.C.); Division of Cardiology, Severance Cardiovascular Hospital and Severance Biomedical Science Institute, Yonsei University College of Medicine, Yonsei University Health System, Seoul, South Korea (H.-J.C.); William Beaumont Hospital, Royal Oaks, MI (K.C., G.R.); Department of Medicine and Radiology, University of Ottawa, Ontario, Canada (B.C.); Baptist Cardiac and Vascular Institute, Miami, FL (R.C.C.); Capitol Cardiology Associates, Albany, NY (A.D.); Duke Clinical Research Institute, Durham, NC (A.D.); Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria (G.F.); Division of Cardiology, Deutsches Herzzentrum Munchen, Munich, Germany (M.H., J.H.); Department of Nuclear Medicine, University Hospital, Zurich, Switzerland (P.A.K.); Seoul National University Hospital, South Korea (Y.-J.K.); Department of Surgery, Curry Cabral Hospital, Lisbon, Portugal (H.M.); Department of Cardiology at the Lady Davis Carmel Medical Center, The Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, (R.R.); Department of Medicine, Walter Reed Medical Center, Washington, DC (T.C.V.); and Department of Radiology, New York-Presbyterian Hospital and the Weill Cornell Medical College, New York (J.M.).

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March 2017

Cardiac Computed Tomography and Magnetic Resonance Imaging in the Evaluation of Mitral and Tricuspid Valve Disease: Implications for Transcatheter Interventions.

Circ Cardiovasc Imaging 2017 Mar;10(3)

From the Department of Cardiology, Concord Hospital, University of Sydney, Australia (C.N.); Department of Radiology and Division of Cardiology, Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, Vancouver, Canada (P.B., J.L.); and Division of Cardiology, Department of Medicine, University of Pittsburgh Medical Center, PA (J.L.C.).

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March 2017

Stroke Related to Transcatheter Heart Valve Thrombosis.

J Heart Valve Dis 2016 11;25(6):756-759

Department of Cardiology, Aarhus University Hospital Skejby, Aarhus N, Denmark.

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November 2016