Publications by authors named "Jonathon Huntington"

1 Publications

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Frequency and abundance of alphaherpesvirus DNA in human thoracic sympathetic ganglia.

J Virol 2014 Jul 30;88(14):8189-92. Epub 2014 Apr 30.

Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA Department of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Alphaherpesvirus reactivation from thoracic sympathetic ganglia (TSG) and transaxonal spread to target organs cause human visceral disease. Yet alphaherpesvirus latency in TSG has not been well characterized. In this study, quantitative PCR detected varicella-zoster virus (VZV), herpes simplex virus 1 (HSV-1), and HSV-2 DNA in 117 fresh TSG obtained postmortem from 15 subjects. VZV DNA was found in 76 (65%) ganglia from all subjects, HSV-1 DNA was found in 5 (4%) ganglia from 3 subjects, and no HSV-2 was found.
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http://dx.doi.org/10.1128/JVI.01070-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097807PMC
July 2014