Publications by authors named "Jonathan W Heusel"

26Publications

Identification of challenges and a framework for implementation of the AMP/ASCO/CAP classification guidelines for reporting somatic variants.

Pract Lab Med 2020 Aug 31;21:e00170. Epub 2020 May 31.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1016/j.plabm.2020.e00170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286953PMC
August 2020

Diagnostic Utility of Next-Generation Sequencing for Disorders of Somatic Mosaicism: A Five-Year Cumulative Cohort.

Am J Hum Genet 2019 10;105(4):734-746

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Genetics, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817554PMC
October 2019

A Multimodality Approach to Assessing Factor I Genetic Variants in Atypical Hemolytic Uremic Syndrome.

Kidney Int Rep 2019 Jul 9;4(7):1007-1017. Epub 2019 Apr 9.

Department of Medicine, Division of Rheumatology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1016/j.ekir.2019.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609824PMC
July 2019

Optimization of Population Frequency Cutoffs for Filtering Common Germline Polymorphisms from Tumor-Only Next-Generation Sequencing Data.

J Mol Diagn 2019 09 25;21(5):903-912. Epub 2019 Jun 25.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri.

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http://dx.doi.org/10.1016/j.jmoldx.2019.05.005DOI Listing
September 2019

Beyond sequence variation: assessment of copy number variation in adult glioblastoma through targeted tumor somatic profiling.

Hum Pathol 2019 04 27;86:170-181. Epub 2018 Dec 27.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.12.004DOI Listing
April 2019

Natural Killer Cell Recruitment to the Lung During Influenza A Virus Infection Is Dependent on CXCR3, CCR5, and Virus Exposure Dose.

Front Immunol 2018 17;9:781. Epub 2018 Apr 17.

Interdisciplinary Graduate Program in Immunology, Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913326PMC
June 2019

Clinical Targeted Next-Generation Sequencing Shows Increased Mutational Load in Endometrioid-type Endometrial Adenocarcinoma With Deficient DNA Mismatch Repair.

Int J Gynecol Pathol 2018 Nov;37(6):581-589

Departments of Pathology and Immunology (P.J.L., S.M., E.J.D., J.W.H., I.S.H.) Obstetrics and Gynecology (I.S.H.), Washington University School of Medicine, St Louis, Missouri.

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http://Insights.ovid.com/crossref?an=00004347-900000000-9924
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http://dx.doi.org/10.1097/PGP.0000000000000459DOI Listing
November 2018

amplification in colorectal adenocarcinoma.

Cold Spring Harb Mol Case Stud 2017 Nov 21;3(6). Epub 2017 Nov 21.

Department of Pathology and Immunology, Washington University in St. Louis, Missouri 63130, USA.

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http://dx.doi.org/10.1101/mcs.a001495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701301PMC
November 2017

Routine use of clinical exome-based next-generation sequencing for evaluation of patients with thrombotic microangiopathies.

Mod Pathol 2017 12 28;30(12):1739-1747. Epub 2017 Jul 28.

Department of Pathology and Immunology, Division of Anatomic and Molecular Pathology, Washington University School of Medicine, St Louis, MO, USA.

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http://www.nature.com/doifinder/10.1038/modpathol.2017.90
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http://dx.doi.org/10.1038/modpathol.2017.90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716882PMC
December 2017

Concurrent MPL W515L and Y591D mutations in a patient with myelofibrosis.

Blood Cells Mol Dis 2016 09 26;60:1-2. Epub 2016 May 26.

Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2016.05.010DOI Listing
September 2016

Extrinsic allospecific signals of hematopoietic origin dictate iNKT cell lineage-fate decisions during development.

Sci Rep 2016 06 29;6:28837. Epub 2016 Jun 29.

Department of Surgery, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1038/srep28837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926280PMC
June 2016

Prenatal Allogeneic Tolerance in Mice Remains Stable Despite Potent Viral Immune Activation.

J Immunol 2015 Oct 11;195(8):4001-9. Epub 2015 Sep 11.

Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; University of Cincinnati College of Medicine, Cincinnati, OH 45229;

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http://dx.doi.org/10.4049/jimmunol.1500844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592829PMC
October 2015

Prenatal Allospecific NK Cell Tolerance Hinges on Instructive Allorecognition through the Activating Receptor during Development.

J Immunol 2015 Aug 1;195(4):1506-16. Epub 2015 Jul 1.

Department of Surgery, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45229;

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http://dx.doi.org/10.4049/jimmunol.1500463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574102PMC
August 2015

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

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http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

The Glycophosphatidylinositol Anchor of the MCMV Evasin, m157, Facilitates Optimal Cell Surface Expression and Ly49 Receptor Recognition.

PLoS One 2013 19;8(6):e67295. Epub 2013 Jun 19.

Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America ; The Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067295PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686720PMC
October 2017

Role of NK cell subsets in organ-specific murine melanoma metastasis.

PLoS One 2013 11;8(6):e65599. Epub 2013 Jun 11.

Iowa City VA Medical Center and the Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065599PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679158PMC
January 2014

Perforin plays an unexpected role in regulating T-cell contraction during prolonged Listeria monocytogenes infection.

Eur J Immunol 2012 Mar 18;42(3):629-40. Epub 2012 Jan 18.

Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1002/eji.201141902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418886PMC
March 2012

Innate immune control and regulation of influenza virus infections.

J Leukoc Biol 2009 Oct 30;86(4):803-12. Epub 2009 Jul 30.

Department of Pathology and Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1189/jlb.0509368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752015PMC
October 2009

Characterization of murine cytomegalovirus m157 from infected cells and identification of critical residues mediating recognition by the NK cell receptor Ly49H.

J Immunol 2008 Jul;181(1):265-75

Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507881PMC
http://dx.doi.org/10.4049/jimmunol.181.1.265DOI Listing
July 2008

Natural killer cells: emerging concepts in immunity to infection and implications for assessment of immunodeficiency.

Curr Opin Pediatr 2003 Dec;15(6):586-93

Departments of Pathology and Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa and the Iowa City VA Medical Center, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1097/00008480-200312000-00008DOI Listing
December 2003

Recognition of a virus-encoded ligand by a natural killer cell activation receptor.

Proc Natl Acad Sci U S A 2002 Jun 11;99(13):8826-31. Epub 2002 Jun 11.

Howard Hughes Medical Institute, and Division of Rheumatology, Department of Medicine, Washington University School of Medicine, and Barnes-Jewish Hospital, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.092258599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC124383PMC
June 2002