Jonathan N Barker

Jonathan N Barker

UNVERIFIED PROFILE

Are you Jonathan N Barker?   Register this Author

Register author
Jonathan N Barker

Jonathan N Barker

Publications by authors named "Jonathan N Barker"

Are you Jonathan N Barker?   Register this Author

75Publications

1995Reads

8Profile Views

Interleukin-36 promotes systemic Type-I IFN responses in severe forms of psoriasis.

J Invest Dermatol 2019 Sep 17. Epub 2019 Sep 17.

Department of Medical and Molecular Genetics, School of Basic & Medical Biosciences, King's College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2019.08.444DOI Listing
September 2019

Morphologic Switch From Psoriasiform to Eczematous Dermatitis After Anti-IL-17 Therapy: A Case Series.

JAMA Dermatol 2019 Jul 10. Epub 2019 Jul 10.

St John's Institute of Dermatology, London, England.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamadermatol.2019.1268DOI Listing
July 2019

Prevalence of Advanced Liver Fibrosis in Patients With Severe Psoriasis.

JAMA Dermatol 2019 Jun 5. Epub 2019 Jun 5.

St John's Institute of Dermatology, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamadermatol.2019.0721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552112PMC
June 2019

Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.

Nat Commun 2019 03 8;10(1):1150. Epub 2019 Mar 8.

St. John's Institute of Dermatology, King's College London, London, Guy's Hospital, London, SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09117-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408457PMC
March 2019

Reply.

J Allergy Clin Immunol 2019 Feb 1;143(2):810-811. Epub 2019 Jan 1.

Skin Inflammation Genetics Group, Department of Medical and Molecular Genetics, King's College, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2018.11.010DOI Listing
February 2019

Juvenile generalized pustular psoriasis is a chronic recalcitrant disease: an analysis of 27 patients seen in a tertiary hospital in Johor, Malaysia.

Int J Dermatol 2017 Apr 14;56(4):392-399. Epub 2017 Feb 14.

Department of Dermatology Hospital Sultanah Aminah, Johor Bahru, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ijd.13489DOI Listing
April 2017

Update on psoriasis immunopathogenesis and targeted immunotherapy.

Semin Immunopathol 2016 Jan 16;38(1):11-27. Epub 2015 Nov 16.

St John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00281-015-0539-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706579PMC
January 2016

Differential Drug Survival of Biologic Therapies for the Treatment of Psoriasis: A Prospective Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

J Invest Dermatol 2015 Nov 8;135(11):2632-2640. Epub 2015 Jun 8.

Dermatology Centre, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2015.208DOI Listing
November 2015

Genetics of psoriasis.

Dermatol Clin 2015 Jan;33(1):1-11

Division of Genetics and Molecular Medicine, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, King's College London, 9th Floor, Tower Wing, London SE1 9RT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2014.09.001DOI Listing
January 2015

Polymorphisms in IL-1B distinguish between psoriasis of early and late onset.

J Invest Dermatol 2014 May 12;134(5):1459-1462. Epub 2013 Nov 12.

The Dermatology Centre, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0022202X153676
Publisher Site
http://dx.doi.org/10.1038/jid.2013.485DOI Listing
May 2014

Generalized pustular eruptions: time to adapt the disease taxonomy to the genetic architecture?

J Invest Dermatol 2014 Feb 16;134(2):580-581. Epub 2013 Aug 16.

Division of Genetics and Molecular Medicine, Guy's Hospital, King's College, London, UK; Division of Genetics and Molecular Medicine, St John's Institute of Dermatology, Guy's Hospital, London, UK; Guy's and St Thomas' NHS Foundation Trust, Skin Therapy Research Unit, St John's Institute of Dermatology, St Thomas' Hospital, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2013.349DOI Listing
February 2014

Loss of IL36RN function does not confer susceptibility to psoriasis vulgaris.

J Invest Dermatol 2014 Jan 21;134(1):271-273. Epub 2013 Jun 21.

Division of Genetics and Molecular Medicine, King's College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2013.285DOI Listing
January 2014

Psoriasis and cardiovascular disease: where is the risk?

J Invest Dermatol 2013 Oct;133(10):2308-2311

St John's Institute of Dermatology, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2013.207DOI Listing
October 2013

γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis.

J Invest Dermatol 2013 Mar 25;133(3):601-607. Epub 2012 Oct 25.

Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2012.372DOI Listing
March 2013

Demyelination during tumour necrosis factor antagonist therapy for psoriasis: a case report and review of the literature.

J Dermatolog Treat 2013 Feb 11;24(1):38-49. Epub 2012 Mar 11.

St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/09546634.2012.660520DOI Listing
February 2013

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.

Hum Mol Genet 2012 Dec 21;21(23):5185-92. Epub 2012 Aug 21.

National Institute for Health Research, Biomedical Research Centre, Guy’s and St Thomas’ NHS Foundation Trust, Toronto, ON, Canada M5T 1R8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/dds344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490509PMC
December 2012

Mutations in the γ-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa).

J Invest Dermatol 2012 Oct 24;132(10):2459-2461. Epub 2012 May 24.

Division of Genetics and Molecular Medicine, King's College London School of Medicine, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2012.162DOI Listing
October 2012

Psoriasis and other complex trait dermatoses: from Loci to functional pathways.

J Invest Dermatol 2012 Mar 8;132(3 Pt 2):915-22. Epub 2011 Dec 8.

Division of Genetics and Molecular Medicine, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2011.395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378482PMC
March 2012

Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis.

Hum Mol Genet 2011 Aug 13;20(16):3129-37. Epub 2011 May 13.

Division of Immunology, Infection and Inflammatory Disease, King’s College London, School of Medicine at Guy’s, King’s College and St Thomas’ Hospitals, London SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddr215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140818PMC
August 2011

The value of monitoring ciclosporin concentration 2 hours post-dose (C2) in dermatology: a prospective cohort study.

J Dermatolog Treat 2011 Apr 1;22(2):79-85. Epub 2010 Aug 1.

Skin Therapy Research Unit, St John's Institute of Dermatology, Guy's and St Thomas' Hospital NHS Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/09546630903575539DOI Listing
April 2011

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Nat Genet 2010 Nov 17;42(11):985-90. Epub 2010 Oct 17.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749730PMC
November 2010

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions.

J Invest Dermatol 2010 Jul 6;130(7):1785-96. Epub 2010 May 6.

Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2010.103DOI Listing
July 2010

Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis.

J Invest Dermatol 2008 Aug 7;128(8):1925-9. Epub 2008 Feb 7.

Dermatological Sciences, The University of Manchester, Salford Royal Hospital, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2008.16DOI Listing
August 2008

Filaggrin null alleles are not associated with psoriasis.

J Invest Dermatol 2007 Aug 5;127(8):1878-82. Epub 2007 Apr 5.

Epithelial Genetics Group, Human Genetics Unit, Division of Pathology and Neuroscience, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.jid.5700817DOI Listing
August 2007

Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.

J Invest Dermatol 2007 Aug 5;127(8):1860-7. Epub 2007 Apr 5.

King's College, Skin Therapy Research Unit, St John's Institute of Dermatology, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.jid.5700808DOI Listing
August 2007

Placebo response in two long-term randomized psoriasis studies that were negative for rosiglitazone.

Am J Clin Dermatol 2007 ;8(2):93-102

Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2165/00128071-200708020-00005DOI Listing
June 2007

Genetic association analysis using data from triads and unrelated subjects.

Am J Hum Genet 2005 Apr 14;76(4):592-608. Epub 2005 Feb 14.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/429225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1199297PMC
April 2005

A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups.

Hum Mol Genet 2004 Oct 27;13(20):2361-8. Epub 2004 Aug 27.

Department of Genetics, University of Leicester, Leicester LE1 7RH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddh273DOI Listing
October 2004

An update on the genetics of psoriasis.

Dermatol Clin 2004 Oct;22(4):339-47, vii

Division of Medical Genetics, Department of Genetics and Cardiovascular Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0733-8635(03)00125-6DOI Listing
October 2004

Basal cell carcinoma is associated with high TNF-alpha release but nor with TNF-alpha polymorphism at position--308.

Exp Dermatol 2003 Dec;12(6):772-6

Department of Dermatology, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.

View Article

Download full-text PDF

Source
December 2003

Genetics of psoriasis: the potential impact on new therapies.

J Am Acad Dermatol 2003 Aug;49(2 Suppl):S51-6

Department of Genetics, Pediatrics, and Medicine, Washington University School of Medicine, Box 8232, 4566 Scott Avenue, St Louis, MO 63110, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0190-9622(03)01135-6DOI Listing
August 2003