Jonathan L Halperin

Jonathan L Halperin

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Jonathan L Halperin

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Thromboembolism in the Absence of Atrial Fibrillation.

Am J Cardiol 2019 Jul 25;124(2):303-311. Epub 2019 Apr 25.

The Cardiovascular Institute, Mount Sinai Medical Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2019.04.027DOI Listing
July 2019

Improved scoring system for the electrocardiographic diagnosis of left ventricular hypertrophy.

World J Cardiol 2019 Mar;11(3):94-102

Division of Cardiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center, New York, NY 10029, United States.

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http://dx.doi.org/10.4330/wjc.v11.i3.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475698PMC
March 2019

Association of International Normalized Ratio Stability and Bleeding Outcomes Among Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention.

Circ Cardiovasc Interv 2019 Feb;12(2):e007124

Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.K., M.K.Y., T.N., C.M.G.).

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007124DOI Listing
February 2019

Deep learning for cardiovascular medicine: a practical primer.

Eur Heart J 2019 Feb 27. Epub 2019 Feb 27.

Cardiovascular Institute and Department of Cardiovascular Medicine, Stanford University Medical Center, Stanford, CA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehz056DOI Listing
February 2019

Three-dimensional echocardiography demonstrates a skewered left ventricular thrombus in a patient with a heart transplant.

Echocardiography 2018 12 18;35(12):2117-2120. Epub 2018 Oct 18.

Icahn School of Medicine, Mount Sinai Medical Center, New York, New York.

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http://doi.wiley.com/10.1111/echo.14158
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http://dx.doi.org/10.1111/echo.14158DOI Listing
December 2018

No conflict of interest in data monitoring.

Science 2018 12;362(6419):1123

Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA.

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http://dx.doi.org/10.1126/science.aau9738DOI Listing
December 2018

Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness.

N Engl J Med 2018 Sep 26;379(12):1118-1127. Epub 2018 Aug 26.

From the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Feinstein Institute for Medical Research, and the Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health at Lenox Hill Hospital (A.C.S.), and the Cardiovascular Institute, Mount Sinai Medical Center (J.L.H.) - all in New York; the Department of Medicine and Surgery, University of Insubria, Varese, Italy (W.A.); the Stanford Stroke Center, Stanford University Medical Center, Stanford (G.W.A.), and the University of California at Davis, Sacramento (G.A.M.) - both in California; the Department of Medicine, Intermountain Medical Center, and Department of Medicine, University of Utah, Salt Lake City (C.G.E.); Division of Cardiology, University of Colorado School of Medicine, and CPC Clinical Research, Aurora (W.R.H.); Département Hospitalo-Universitaire FIRE (Fibrose Inflammation Remodelage), University Paris Diderot, Assistance Publique-Hôpitaux de Paris, and INSERM Unité 1148, Paris (P.G.S.); Imperial College, Royal Brompton Hospital, London (P.G.S.); McMaster University and the Thrombosis and Atherosclerosis Research Institute - both in Hamilton, ON, Canada (J.I.W.); Janssen Research and Development, Raritan (E.S., E.S.B.), and the Thrombosis and Hematology Therapeutic Area, Clinical Development, Pharmaceuticals, Bayer U.S., Whippany (T.E.S.) - both in New Jersey; and the College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City (G.E.R.).

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http://dx.doi.org/10.1056/NEJMoa1805090DOI Listing
September 2018

US Preventive Services Task Force recommendation statement regarding screening for peripheral artery disease with the ankle-brachial index: déjà vu all over again.

Lancet 2018 09;392(10153):1160-1162

Zena and Michael A Wiener Cardiovascular Institute and Marie-Josée and Henry R Kravis Center for Cardiovascular Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1016/S0140-6736(18)31650-7DOI Listing
September 2018

Gender Differences in Antithrombotic Treatment for Newly Diagnosed Atrial Fibrillation: The GLORIA-AF Registry Program.

Am J Med 2018 Aug 11;131(8):945-955.e3. Epub 2018 Apr 11.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2018.03.024DOI Listing
August 2018

Stroke-prevention strategies in North American patients with atrial fibrillation: The GLORIA-AF registry program.

Clin Cardiol 2018 Jun 10;41(6):744-751. Epub 2018 May 10.

Department of Medicine, Division of Cardiology, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1002/clc.22936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032943PMC
June 2018

Two-year follow-up of patients treated with dabigatran for stroke prevention in atrial fibrillation: Global Registry on Long-Term Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF) registry.

Am Heart J 2018 04 31;198:55-63. Epub 2017 Aug 31.

Institute of Cardiovascular Sciences, University of Birmingham, UK and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2017.08.018DOI Listing
April 2018

The World Heart Federation Roadmap for Nonvalvular Atrial Fibrillation.

Glob Heart 2017 12 21;12(4):273-284. Epub 2017 Mar 21.

Department of Cardiac Sciences, Cumming School of Medicine, Division of Cardiology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada; Alberta Health Services, Foothills Medical Centre, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.gheart.2017.01.015DOI Listing
December 2017

Dronedarone exerts anticoagulant and antiplatelet effects independently of its antiarrhythmic actions.

Atherosclerosis 2017 Nov 28;266:81-86. Epub 2017 Sep 28.

Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.09.029DOI Listing
November 2017

Persistence With Dabigatran Therapy at 2 Years in Patients With Atrial Fibrillation.

J Am Coll Cardiol 2017 Sep;70(13):1573-1583

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2017.07.793DOI Listing
September 2017

Preventing Myocardial Infarction in Patients With Atrial Fibrillation: Another Piece of the Puzzle.

J Am Coll Cardiol 2017 06;69(24):2910-2912

Cardiovascular Institute, The Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.05.006DOI Listing
June 2017

Noncentral Nervous System Systemic Embolism in Patients With Atrial Fibrillation: Results From ROCKET AF (Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation).

Circ Cardiovasc Qual Outcomes 2017 05;10(5)

From the Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (R.O., D.W., W.S.J., M.R.P.); Department of Statistics, North Carolina State University, Raleigh (D.H.); Mount Sinai Medical Center, New York, NY (J.L.H.); Department of Cardiovascular Medicine, Hospital of the University of Münster, Germany (G.B.); Massachusetts General Hospital and Harvard Medical School, Boston (D.E.S.); University of Edinburgh and Royal Infirmary of Edinburgh, Scotland, United Kingdom (K.A.A.F.); School of Medicine and Pharmacology, University of Western Australia, Crawley (G.J.H.); and Stanford University School of Medicine, CA (K.W.M.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.116.003520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485838PMC
May 2017

Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves.

Circulation 2017 03 16;135(13):1273-1275. Epub 2017 Feb 16.

From Brigham & Women's Hospital, Harvard Medical School, Boston, MA (A.P.C.); Institute of Cardiology and Center of Excellence on Aging, G. d'Annunzio University, Chieti, Italy (R.D.C., G.R.); Mount Sinai Hospital, Icahn School of Medicine at Mount Sinai, New York (J.L.H.); TIMI Study Group (Thrombolysis in Myocardial Infarction), Boston, MA (C.T.R., M.T., F.N., E.A., R.P.G.); and Daiichi Sankyo Pharma Development, Edison, NJ (M.P.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026714DOI Listing
March 2017

Treatment Consistency Across Levels of Baseline Renal Function With Rivaroxaban or Warfarin: A ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) Analysis.

Circulation 2017 03;135(10):1001-1003

From Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (S.M.L., C.B.F., A.S.H., Y.L., J.P.P., M.R.P.); Division of Cardiology, University of British Columbia, Vancouver, Canada (C.B.F.); Department of Cardiovascular Medicine, University of Münster, Germany (G.B.); Stanford University School of Medicine, CA (K.W.M.); Massachusetts General Hospital and Harvard Medical School, Boston (D.E.S.); Ruprecht-Karls-University, Heidelberg, Germany (W.H.); Cardiovascular Institute, Mount Sinai Medical Center, NY (J.L.H.); School of Medicine and Pharmacology, The University of Western Australia, Crawley (G.J.H.); Bayer HealthCare Pharmaceuticals, Parsippany, NJ (S.D.B.); Janssen Research and Development LLC, Raritan, NJ (C.C.N.); University of Cincinnati College of Medicine, OH (R.C.B.); and University of Edinburgh and Royal Infirmary of Edinburgh, UK (K.A.A.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024666DOI Listing
March 2017

Temporal trends in ischemic stroke and anticoagulation therapy for non-valvular atrial fibrillation: effect of diabetes.

J Diabetes 2017 Feb 13;9(2):115-122. Epub 2016 Apr 13.

Division of Cardiology, Department of Medicine, Hennepin County Medical Center and University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1111/1753-0407.12392DOI Listing
February 2017

Determinants of Time in Therapeutic Range in Patients Receiving Oral Anticoagulants (A Substudy of IMPACT).

Am J Cardiol 2016 Dec 31;118(11):1680-1684. Epub 2016 Aug 31.

The Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, New York; The Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai Medical Center, New York, New York.

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http://dx.doi.org/10.1016/j.amjcard.2016.08.047DOI Listing
December 2016

Low intraoperative heart rate volatility is associated with early postoperative mortality in general surgical patients: a retrospective case-control study.

J Clin Monit Comput 2016 Dec 17;30(6):911-918. Epub 2015 Oct 17.

Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/s10877-015-9792-6DOI Listing
December 2016

When Should We Go With HALT?

JACC Cardiovasc Imaging 2016 Dec 8. Epub 2016 Dec 8.

Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

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http://dx.doi.org/10.1016/j.jcmg.2016.11.002DOI Listing
December 2016

Stroke risk assessment in atrial fibrillation: risk factors and markers of atrial myopathy.

Nat Rev Cardiol 2016 09 7;13(9):549-59. Epub 2016 Jul 7.

Duke University Medical Center, 2400 Pratt Street, Durham, North Carolina 27705, USA.

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http://dx.doi.org/10.1038/nrcardio.2016.106DOI Listing
September 2016

Use of concomitant aspirin in patients with atrial fibrillation: Findings from the ROCKET AF trial.

Am Heart J 2016 09 22;179:77-86. Epub 2016 Jun 22.

Duke Clinical Research Institute, Durham, NC; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2016.05.019DOI Listing
September 2016

Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation.

Thromb Haemost 2016 08 23;116(3):544-53. Epub 2016 Jun 23.

John M. Kittelson, Ph.D., Historic Building 500, Box B119, University of Colorado Anschutz Medical Campus, 13001 East 17th Place, Aurora, CO 80045, USA, Tel.: +1 303 724 4364, E-mail:

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http://dx.doi.org/10.1160/TH15-12-1000DOI Listing
August 2016

Current strategies in the evaluation and management of cocaine-induced chest pain.

Cardiol Rev 2015 Nov-Dec;23(6):303-11

From the *Department of Medicine, Surat Municipal Institute of Medical Education and Research, Surat, Gujarat, India; †Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, NY; ‡Department of Internal Medicine, St John Hospital and Medical Center, Wayne State University School of Medicine, Detroit, MI; §Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL; and ¶VA Ann Arbor Health Care System, University of Michigan, Ann Arbor, MI.

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http://pdfs.journals.lww.com/cardiologyinreview/2015/11000/C
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CRD.0000000000000050DOI Listing
July 2016

A Baby in the Bathwater: Preserving Evidence-Based Medicine.

J Am Coll Cardiol 2016 07;68(2):214-6

Mount Sinai Medical Center, New York, New York.

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http://dx.doi.org/10.1016/j.jacc.2016.05.023DOI Listing
July 2016

Response by Piccini et al to Letters Regarding Article, "Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation".

Circulation 2016 Jul;134(2):e7-8

From the Duke Clinical Research Institute (J.P.P., A.S.H., M.R.P.) and Duke Heart Center (J.P.P., J.B.W., M.R.P.), Duke University Medical Center, Durham, NC; University of Cincinnati College of Medicine, Cincinnati, OH (R.C.B.); Hospital of the University of Münster, Germany (G.B.); Bayer HealthCare Pharmaceuticals, Parsippany, NJ (S.D.B.); Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, NY (J.L.H.); School of Medicine and Pharmacology, University of Western Australia, Crawley, Australia (G.J.H.); Ruprecht-Karls-University, Heidelberg, Germany (W.H.); Department of Medicine, Stanford University, CA (K.W.M.); Janssen Pharmaceutical Research and Development, Raritan, NJ (C.C.N.); Massachusetts General Hospital, and Harvard Medical School, Boston (D.E.S.); and University of Edinburgh and Royal Infirmary of Edinburgh, UK (K.A.A.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022737DOI Listing
July 2016

2015 ACC/AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST-elevation myocardial Infarction: An update of the 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention and the 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions.

Catheter Cardiovasc Interv 2016 May;87(6):1001-19

Former Task Force member; current member during the writing effort.

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http://dx.doi.org/10.1002/ccd.26325DOI Listing
May 2016

Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation.

Circulation 2016 Jan 16;133(4):352-60. Epub 2015 Dec 16.

From Duke Clinical Research Institute, Durham, NC (J.P.P., A.S.H., M.R.P.); Duke Heart Center, Duke University Medical Center, Durham, NC (J.P.P., J.B.W., M.R.P.); University of Cincinnati College of Medicine, OH (R.C.B.); Hospital of the University of Münster, Germany (G.B.); Bayer HealthCare Pharmaceuticals, Whippany, NJ (S.D.B.); Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, NY (J.L.H.); School of Medicine and Pharmacology, University of Western Australia, Crawley, WA (G.J.H.); Ruprecht-Karls-University, Heidelberg, Germany (W.H.); Department of Medicine, Stanford University, Palo Alto, CA (K.W.M.); Janssen Pharmaceutical Research and Development, Raritan, NJ (C.C.N.); Massachusetts General Hospital and Harvard Medical School, Boston (D.E.S.); and University of Edinburgh and Royal Infirmary of Edinburgh, UK (K.A.A.F.).

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https://circ.ahajournals.org/content/early/2015/12/16/CIRCUL
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http://circ.ahajournals.org/content/early/2015/12/16/CIRCULA
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http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.018544DOI Listing
January 2016

Standards and Barriers in Acute Stroke Therapy: A Leap Forward in the Evolution of Endovascular Interventions for Stroke.

J Am Coll Cardiol 2015 Dec;66(22):2506-9

The Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

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http://dx.doi.org/10.1016/j.jacc.2015.09.069DOI Listing
December 2015

Taking TASC to TASK: Evolving from nomenclature to guidelines.

Vasc Med 2015 Oct 12;20(5):463-4. Epub 2015 Aug 12.

The Cardiovascular Institute, Mount Sinai Medical Center, New York, NY, USA

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http://dx.doi.org/10.1177/1358863X15598022DOI Listing
October 2015

Extracranial Systemic Embolic Events in Patients With Nonvalvular Atrial Fibrillation: Incidence, Risk Factors, and Outcomes.

Circulation 2015 Sep 29;132(9):796-803. Epub 2015 Jul 29.

From Lillehei Heart Institute and Cardiovascular Division, University of Minnesota Medical School, Minneapolis (W.B., S.D., A.T.H.); Department of Medicine, McMaster University, Hamilton, Ontario (S.J.C., S.C., J.P., J.W.E., S.Y.); Mt. Sinai School of Medicine, New York (J.L.H.); Division of Cardiology, Minneapolis Veterans Administration Medical Center, MN (S.A.); Lankenau Institute for Medical Research, Wynnewood, PA (M.D.E.); and Uppsala Clinical Research Center, Sweden (L.G.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013243DOI Listing
September 2015

Age, Ethnicity, and Stroke Risk in Patients With Atrial Fibrillation: Another Stitch in the Patchwork.

J Am Coll Cardiol 2015 Sep;66(12):1348-9

Cardiovascular Institute, Mount Sinai Medical Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.08.003DOI Listing
September 2015

COCATS 4 Introduction.

J Am Coll Cardiol 2015 May 13;65(17):1724-33. Epub 2015 Mar 13.

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http://dx.doi.org/10.1016/j.jacc.2015.03.020DOI Listing
May 2015

Fibrotic atrial cardiomyopathy, atrial fibrillation, and thromboembolism: mechanistic links and clinical inferences.

J Am Coll Cardiol 2015 May;65(20):2239-51

Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.03.557DOI Listing
May 2015

Variability in low-density lipoprotein cholesterol and cardiovascular risk: should consistency be a new target?

J Am Coll Cardiol 2015 Apr;65(15):1549-51

Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097150075
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http://dx.doi.org/10.1016/j.jacc.2015.02.048DOI Listing
April 2015

Response: “Actually, it’s more of a guideline than a rule”.

J Am Coll Cardiol 2015 Feb;65(4):400

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February 2015

Device-detected atrial fibrillation: what to do with asymptomatic patients?

J Am Coll Cardiol 2015 Jan;65(3):281-94

Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Medical Center, New York, New York.

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http://dx.doi.org/10.1016/j.jacc.2014.10.045DOI Listing
January 2015

Interaction between digoxin and dronedarone in the PALLAS trial.

Circ Arrhythm Electrophysiol 2014 Dec 6;7(6):1019-25. Epub 2014 Nov 6.

From the Division of Clinical Electrophysiology, J.W. Goethe University, Frankfurt, Germany (S.H.H.); Population Health Research Institute, McMaster University, Hamilton, ON, Canada (P.G., S.J.C.); Department of Clinical Sciences, St George's University of London, London, United Kingdom (A.J.C.); The Cardiovascular Institute, Mount Sinai Medical Center, New York, NY (J.L.H.); and Sanofi Recherche, Paris, France (D.R.).

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http://dx.doi.org/10.1161/CIRCEP.114.002046DOI Listing
December 2014

Vorapaxar, combination antiplatelet therapy, and stroke.

J Am Coll Cardiol 2014 Dec 1;64(22):2327-9. Epub 2014 Dec 1.

Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2014.09.038DOI Listing
December 2014

Efficacy and safety of amiodarone in patients with atrial fibrillation in the era of target-specific anticoagulants.

J Am Coll Cardiol 2014 Oct;64(15):1551-3

Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.07.966DOI Listing
October 2014

Thoracic aortic aneurysm and dissection.

J Am Coll Cardiol 2014 Oct;64(16):1725-39

Department of Medicine, Division of Cardiology, Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097140600
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http://dx.doi.org/10.1016/j.jacc.2014.08.025DOI Listing
October 2014