Jonathan L Bramson

Jonathan L Bramson

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Jonathan L Bramson

Publications by authors named "Jonathan L Bramson"

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TGFβ Programs Central Memory Differentiation in -Stimulated Human T Cells.

Cancer Immunol Res 2019 Sep 15;7(9):1426-1439. Epub 2019 Jul 15.

Centre de Recherche de l'Hôpital Maisonneuve-Rosemont (CRHMR), Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0691DOI Listing
September 2019

Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity.

J Clin Invest 2019 02 18;129(2):518-530. Epub 2018 Dec 18.

McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1172/JCI121004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355222PMC
February 2019

Expanded CD56CD16 NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model.

Cancer Immunol Res 2018 10 17;6(10):1174-1185. Epub 2018 Jul 17.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0144DOI Listing
October 2018

HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants.

Cell Rep 2018 07;24(3):642-654

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8N 3Z5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.040DOI Listing
July 2018

Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes.

Methods Mol Biol 2016 ;1458:137-57

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, 1200 Main Street West, Hamilton, ON, Canada, L8N 3Z5.

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http://dx.doi.org/10.1007/978-1-4939-3801-8_11DOI Listing
January 2018

Tumor-targeting domains for chimeric antigen receptor T cells.

Immunotherapy 2017 01;9(1):33-46

Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.2217/imt-2016-0103DOI Listing
January 2017

Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination.

J Immunol 2016 06 27;196(11):4587-95. Epub 2016 Apr 27.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8N 3Z5, Canada

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http://dx.doi.org/10.4049/jimmunol.1600106DOI Listing
June 2016

Chimeric antigen receptor-engineered T cells as oncolytic virus carriers.

Mol Ther Oncolytics 2015 9;2:15014. Epub 2015 Sep 9.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University , Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/mto.2015.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782951PMC
April 2016

Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly.

PLoS One 2014 8;9(8):e104522. Epub 2014 Aug 8.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada; Institute for Infectious Diseases Research, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104522PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126708PMC
December 2015

Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors.

J Immunother Cancer 2015 15;3:55. Epub 2015 Dec 15.

Department Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON Canada.

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http://dx.doi.org/10.1186/s40425-015-0099-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678647PMC
December 2015

T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice.

Mol Ther 2015 Oct 30;23(10):1600-10. Epub 2015 Jun 30.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S15250016163029
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http://dx.doi.org/10.1038/mt.2015.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817919PMC
October 2015

Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity.

Innate Immun 2015 Aug 5;21(6):626-34. Epub 2015 Mar 5.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada

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http://journals.sagepub.com/doi/10.1177/1753425915575078
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http://dx.doi.org/10.1177/1753425915575078DOI Listing
August 2015

An Introduction to Automated Flow Cytometry Gating Tools and Their Implementation.

Front Immunol 2015 27;6:380. Epub 2015 Jul 27.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre (MIRC), McMaster University , Hamilton, ON , Canada.

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http://journal.frontiersin.org/Article/10.3389/fimmu.2015.00
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http://dx.doi.org/10.3389/fimmu.2015.00380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515551PMC
August 2015

Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly.

Mol Immunol 2015 May 5;65(1):148-56. Epub 2015 Feb 5.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada; Institute for Infectious Diseases Research, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2015.01.015DOI Listing
May 2015

Circulating muramyl dipeptide is negatively associated with interleukin-10 in the frail elderly.

Inflammation 2015 Feb;38(1):272-7

Department of Pathology and Molecular Medicine, McMaster University, MDCL 4020 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada.

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http://dx.doi.org/10.1007/s10753-014-0030-zDOI Listing
February 2015

Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling.

Hum Immunol 2014 Dec 13;75(12):1192-6. Epub 2014 Oct 13.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada; Institute for Infectious Diseases Research, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01988859140046
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http://dx.doi.org/10.1016/j.humimm.2014.10.004DOI Listing
December 2014

Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics.

J Gen Virol 2014 Nov 5;95(Pt 11):2504-11. Epub 2014 Aug 5.

School of Cellular and Molecular Medicine, University Walk, University of Bristol, Bristol BS8 1TD, UK

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http://dx.doi.org/10.1099/vir.0.068221-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202269PMC
November 2014

Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop.

BMC Infect Dis 2014 May 9;14:246. Epub 2014 May 9.

Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Perlickstrasse 1, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1186/1471-2334-14-246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028281PMC
May 2014

Maraba virus as a potent oncolytic vaccine vector.

Mol Ther 2014 Feb 25;22(2):420-429. Epub 2013 Oct 25.

McMaster Immunology Research Center, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1038/mt.2013.249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916044PMC
February 2014

The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age.

PLoS Pathog 2012 13;8(12):e1003076. Epub 2012 Dec 13.

McMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.plos.org/10.1371/journal.ppat.1003076
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http://dx.doi.org/10.1371/journal.ppat.1003076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521721PMC
May 2013

Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8(+) T-cell recall responses.

Blood 2013 Mar 16;121(13):2432-9. Epub 2013 Jan 16.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1182/blood-2012-06-438481DOI Listing
March 2013

A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model.

Integr Biol (Camb) 2012 Aug 9;4(8):925-36. Epub 2012 Jul 9.

Department of Chemical Engineering and Mary Babb Randolph Cancer Center, West Virginia University, P.O. Box 6102, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1039/c2ib20053hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428131PMC
August 2012

Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines.

Mol Ther 2012 Apr 20;20(4):860-9. Epub 2011 Dec 20.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/mt.2011.281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321597PMC
April 2012

Multi-stability and multi-instability phenomena in a mathematical model of tumor-immune-virus interactions.

Bull Math Biol 2011 Dec 8;73(12):2932-61. Epub 2011 Apr 8.

Department of Mathematics and Statistics, McMaster University, Hamilton, ON, L8S 4K1, Canada.

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http://dx.doi.org/10.1007/s11538-011-9653-5DOI Listing
December 2011

Defining the critical hurdles in cancer immunotherapy.

Authors:
Bernard A Fox Dolores J Schendel Lisa H Butterfield Steinar Aamdal James P Allison Paolo Antonio Ascierto Michael B Atkins Jirina Bartunkova Lothar Bergmann Neil Berinstein Cristina C Bonorino Ernest Borden Jonathan L Bramson Cedrik M Britten Xuetao Cao William E Carson Alfred E Chang Dainius Characiejus A Raja Choudhury George Coukos Tanja de Gruijl Robert O Dillman Harry Dolstra Glenn Dranoff Lindy G Durrant James H Finke Jerome Galon Jared A Gollob Cécile Gouttefangeas Fabio Grizzi Michele Guida Leif Håkansson Kristen Hege Ronald B Herberman F Stephen Hodi Axel Hoos Christoph Huber Patrick Hwu Kohzoh Imai Elizabeth M Jaffee Sylvia Janetzki Carl H June Pawel Kalinski Howard L Kaufman Koji Kawakami Yutaka Kawakami Ulrich Keilholtz Samir N Khleif Rolf Kiessling Beatrix Kotlan Guido Kroemer Rejean Lapointe Hyam I Levitsky Michael T Lotze Cristina Maccalli Michele Maio Jens-Peter Marschner Michael J Mastrangelo Giuseppe Masucci Ignacio Melero Cornelius Melief William J Murphy Brad Nelson Andrea Nicolini Michael I Nishimura Kunle Odunsi Pamela S Ohashi Jill O'Donnell-Tormey Lloyd J Old Christian Ottensmeier Michael Papamichail Giorgio Parmiani Graham Pawelec Enrico Proietti Shukui Qin Robert Rees Antoni Ribas Ruggero Ridolfi Gerd Ritter Licia Rivoltini Pedro J Romero Mohamed L Salem Rik J Scheper Barbara Seliger Padmanee Sharma Hiroshi Shiku Harpreet Singh-Jasuja Wenru Song Per Thor Straten Hideaki Tahara Zhigang Tian Sjoerd H van Der Burg Paul von Hoegen Ena Wang Marij Jp Welters Hauke Winter Tara Withington Jedd D Wolchok Weihua Xiao Laurence Zitvogel Heinz Zwierzina Francesco M Marincola Thomas F Gajewski Jon M Wigginton Mary L Disis

J Transl Med 2011 Dec 14;9:214. Epub 2011 Dec 14.

Earle A, Chiles Research Institute, Robert W, Franz Research Center, Providence Cancer Center, Providence Portland Medical Center, Portland, OR, USA.

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http://dx.doi.org/10.1186/1479-5876-9-214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338100PMC
December 2011

Optimizing vaccine-induced CD8(+) T-cell immunity: focus on recombinant adenovirus vectors.

Expert Rev Vaccines 2011 Sep;10(9):1307-19

Centre for Gene Therapeutics, Department of Pathology and Molecular Medicine, McMaster University, Room MDCL-5071, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada.

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http://dx.doi.org/10.1586/erv.11.88DOI Listing
September 2011

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells.

Cancer Res 2011 Apr 9;71(7):2497-506. Epub 2011 Feb 9.

Department of Pathology and Molecular Medicine and Medical Sciences Program, McMaster University, Hamilton, Ontario, Canada.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-3025DOI Listing
April 2011

Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production.

Cancer Immunol Immunother 2011 Mar 14;60(3):381-8. Epub 2010 Dec 14.

Department of Surgery, Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, University of British Columbia, 950 West 28th Ave, Vancouver, BC V5Z4H4, Canada.

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http://dx.doi.org/10.1007/s00262-010-0948-4DOI Listing
March 2011

Interactions between the immune system and cancer: a brief review of non-spatial mathematical models.

Bull Math Biol 2011 Jan 12;73(1):2-32. Epub 2010 Mar 12.

Department of Mathematics and Statistic, McMaster University, Hamilton, ON, Canada, L8S 4K1.

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http://dx.doi.org/10.1007/s11538-010-9526-3DOI Listing
January 2011

Surface phenotype and functionality of WNV specific T cells differ with age and disease severity.

PLoS One 2010 Dec 13;5(12):e15343. Epub 2010 Dec 13.

Department of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015343PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001480PMC
December 2010

Applying bioinformatics for antibody epitope prediction using affinity-selected mimotopes - relevance for vaccine design.

Immunome Res 2010 Nov 3;6 Suppl 2:S6. Epub 2010 Nov 3.

Department of Pathology and Molecular Medicine, Centre for Gene Therapeutics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada, L8N 3Z5.

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http://dx.doi.org/10.1186/1745-7580-6-S2-S6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981875PMC
November 2010

Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma.

J Theor Biol 2010 Aug 5;265(3):467-80. Epub 2010 May 5.

Department of Mathematics and Statistics, McMaster University, Hamilton, ON, Canada L8S 4K1.

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http://linkinghub.elsevier.com/retrieve/pii/S002251931000229
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http://dx.doi.org/10.1016/j.jtbi.2010.04.030DOI Listing
August 2010

Potentiating cancer immunotherapy using an oncolytic virus.

Mol Ther 2010 Aug 15;18(8):1430-9. Epub 2010 Jun 15.

Centre for Gene Therapeutics, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/mt.2010.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927075PMC
August 2010

Processing of tumor antigen differentially impacts the development of helper and effector CD4+ T-cell responses.

Mol Ther 2010 Jun 23;18(6):1224-32. Epub 2010 Feb 23.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/mt.2010.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889742PMC
June 2010

Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen.

J Immunol 2010 Apr 17;184(8):4269-75. Epub 2010 Mar 17.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4049/jimmunol.0901447DOI Listing
April 2010

Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus.

J Virol 2009 Dec 16;83(23):12027-36. Epub 2009 Sep 16.

Department of Pathology and Molecular Medicine, McMaster University, Center for Gene Therapeutics, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1128/JVI.00593-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786755PMC
December 2009

Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus.

Mol Ther 2009 Oct 14;17(10):1814-21. Epub 2009 Jul 14.

Centre for Gene Therapeutics, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario L8N 3Z5, Canada.

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http://dx.doi.org/10.1038/mt.2009.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835010PMC
October 2009

Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties.

Blood 2009 Sep 4;114(13):2632-8. Epub 2009 Aug 4.

Department of Medicine and Oncology, Sir Mortimer B. Davis Jewish General Hospital & Lady Davis Institute for Medical Research, Montreal, QC, Canada.

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http://dx.doi.org/10.1182/blood-2009-02-207795DOI Listing
September 2009

CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis.

Eur J Immunol 2009 May;39(5):1252-9

Department of Pathology and Molecular Medicine, McMaster University, Ontario, Canada.

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http://dx.doi.org/10.1002/eji.200839152DOI Listing
May 2009

Neoadjuvant vaccination provides superior protection against tumor relapse following surgery compared with adjuvant vaccination.

Cancer Res 2009 May 21;69(9):3979-85. Epub 2009 Apr 21.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3385DOI Listing
May 2009

Deciphering epitope specificities within polyserum using affinity selection of random peptides and a novel algorithm based on pattern recognition theory.

Mol Immunol 2009 Jan 26;46(3):429-36. Epub 2008 Nov 26.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.molimm.2008.10.013DOI Listing
January 2009

A novel computer algorithm improves antibody epitope prediction using affinity-selected mimotopes: a case study using monoclonal antibodies against the West Nile virus E protein.

Mol Immunol 2008 Nov 29;46(1):125-34. Epub 2008 Aug 29.

Department of Pathology and Molecular Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5.

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http://dx.doi.org/10.1016/j.molimm.2008.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856767PMC
November 2008

Enhanced antitumor immunity elicited by dendritic cell vaccines is a result of their ability to engage both CTL and IFN gamma-producing NK cells.

Mol Ther 2008 Feb 4;16(2):411-8. Epub 2007 Dec 4.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/sj.mt.6300347DOI Listing
February 2008

Enhanced Antitumor Immunity Elicited by Dendritic Cell Vaccines Is a Result of Their Ability to Engage Both CTL and IFNγ-producing NK Cells.

Mol Ther 2008 Feb 7;16(2):411-418. Epub 2016 Dec 7.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1038/sj.mt.6300347DOI Listing
February 2008

T-cell immunity generated by recombinant adenovirus vaccines.

Expert Rev Vaccines 2007 Jun;6(3):347-56

Center for Gene Therapeutics, Department of Pathology and Molecular Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada.

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http://dx.doi.org/10.1586/14760584.6.3.347DOI Listing
June 2007

Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.

J Immunol 2006 Feb;176(4):2568-80

Division of Respiratory Diseases and Allergy, Centre for Gene Therapeutics, Department of Pathology and Molecular Medicine, Master University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4049/jimmunol.176.4.2568DOI Listing
February 2006

Semliki forest virus and Kunjin virus RNA replicons elicit comparable cellular immunity but distinct humoral immunity.

Vaccine 2005 Jul;23(33):4189-94

Center for Gene Therapeutics, Department of Pathology and Molecular Medicine, McMaster University, MDCL-5025, 1200 Main Street West, Hamilton, Ont., Canada L8N 3Z5.

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http://dx.doi.org/10.1016/j.vaccine.2005.04.005DOI Listing
July 2005

Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responses.

J Immunol 2005 Feb;174(3):1664-74

Division of Respiratory Diseases and Allergy, Centre for Gene Therapeutics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4049/jimmunol.174.3.1664DOI Listing
February 2005

CTL-dependent and -independent antitumor immunity is determined by the tumor not the vaccine.

J Immunol 2004 May;172(9):5200-5

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4049/jimmunol.172.9.5200DOI Listing
May 2004

Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin.

Cancer Res 2004 Feb;64(4):1509-14

Department of Pathology and Molecular Medicine, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5.

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http://dx.doi.org/10.1158/0008-5472.can-03-3227DOI Listing
February 2004

Helper-dependent adenoviral vectors containing modified fiber for improved transduction of developing and mature muscle cells.

Hum Gene Ther 2004 Feb;15(2):179-88

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, L8N 325 Canada.

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http://dx.doi.org/10.1089/104303404772679986DOI Listing
February 2004

A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.

J Immunol 2004 Jan;172(2):981-8

Department of Immunology, University of Toronto, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.4049/jimmunol.172.2.981DOI Listing
January 2004

Super-activated interferon-regulatory factors can enhance plasmid immunization.

Vaccine 2003 Mar;21(13-14):1363-70

Department of Pathology and Molecular Medicine, Center for Gene Therapeutics, McMaster University, 1200 Main Street West, Hamilton, Ont., Canada L8N 3Z5.

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http://dx.doi.org/10.1016/s0264-410x(02)00694-1DOI Listing
March 2003

The efficacy of genetic vaccination is dependent upon the nature of the vector system and antigen.

Expert Opin Biol Ther 2002 Jan;2(1):75-85

Department of Pathology and Molecular Medicine, McMaster University, Room HSC-4H21B, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada.

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http://dx.doi.org/10.1517/14712598.2.1.75DOI Listing
January 2002