Jonathan K Pritchard

Jonathan K Pritchard

UNVERIFIED PROFILE

Are you Jonathan K Pritchard?   Register this Author

Register author
Jonathan K Pritchard

Jonathan K Pritchard

Publications by authors named "Jonathan K Pritchard"

Are you Jonathan K Pritchard?   Register this Author

100Publications

2112Reads

28Profile Views

Public Discussion Affects Question Asking at Academic Conferences.

Am J Hum Genet 2019 Jul 27;105(1):189-197. Epub 2019 Jun 27.

Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA; Marcus Autism Center, Children's Healthcare of Atlanta, Atlanta, GA 30329, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2019.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612753PMC
July 2019

Trans Effects on Gene Expression Can Drive Omnigenic Inheritance.

Cell 2019 May;177(4):1022-1034.e6

Departments of Biology and Genetics and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553491PMC
May 2019

Evidence for Weak Selective Constraint on Human Gene Expression.

Genetics 2019 02 15;211(2):757-772. Epub 2018 Dec 15.

Department of Biology, Stanford University, California 94305

View Article

Download full-text PDF

Source
http://www.genetics.org/lookup/doi/10.1534/genetics.118.3018
Publisher Site
http://dx.doi.org/10.1534/genetics.118.301833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366908PMC
February 2019

High-resolution mapping of cancer cell networks using co-functional interactions.

Mol Syst Biol 2018 12 20;14(12):e8594. Epub 2018 Dec 20.

Department of Genetics, Stanford University, Stanford, CA, USA

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300813PMC
http://dx.doi.org/10.15252/msb.20188594DOI Listing
December 2018

Interpreting polygenic scores, polygenic adaptation, and human phenotypic differences.

Evol Med Public Health 2019 27;2019(1):26-34. Epub 2018 Dec 27.

Department of Biology, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/emph/eoy036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393779PMC
December 2018

Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing.

Cell 2018 10 20;175(2):544-557.e16. Epub 2018 Sep 20.

Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.08.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563827PMC
October 2018

Post-translational buffering leads to convergent protein expression levels between primates.

Genome Biol 2018 06 27;19(1):83. Epub 2018 Jun 27.

Department of Genetics, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-018-1451-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020354PMC
June 2018

Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.

Cell Stem Cell 2018 04;22(4):600-607.e4

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Lorry I. Lokey Stem Cell Research Building, 265 Campus Drive, Stanford, CA, USA; Department of Genetics, Stanford University, Stanford, CA, USA; Division of Stem Cell Therapy, Center for Stem Cell Biology and Regeneration Medicine, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896201PMC
April 2018

Annotation-free quantification of RNA splicing using LeafCutter.

Nat Genet 2018 01 11;50(1):151-158. Epub 2017 Dec 11.

Department of Genetics, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-017-0004-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742080PMC
January 2018

Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression.

Am J Hum Genet 2017 Nov 26;101(5):686-699. Epub 2017 Oct 26.

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2017.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673624PMC
November 2017

Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates.

Proc Natl Acad Sci U S A 2017 11 14;114(48):12779-12784. Epub 2017 Nov 14.

Department of Biology, Stanford University, Stanford, CA 94305;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1708151114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715747PMC
November 2017

Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype.

PLoS Comput Biol 2017 Aug 3;13(8):e1005629. Epub 2017 Aug 3.

Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1005629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542400PMC
August 2017

An Expanded View of Complex Traits: From Polygenic to Omnigenic.

Cell 2017 Jun;169(7):1177-1186

Department of Genetics, Stanford University, Stanford, CA 94305, USA; Department of Biology, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.05.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536862PMC
June 2017

Rapid evolution of the human mutation spectrum.

Elife 2017 04 25;6. Epub 2017 Apr 25.

Department of Genetics, Stanford University, Stanford, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.24284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435464PMC
April 2017

Tracing the peopling of the world through genomics.

Nature 2017 01;541(7637):302-310

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, 1350 Copenhagen K, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature21347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772775PMC
January 2017

A Bibliometric History of the Journal GENETICS.

Genetics 2016 12 7;204(4):1337-1342. Epub 2016 Dec 7.

Howard Hughes Medical Institute, Chevy Chase, Maryland 20815.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.116.196964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161266PMC
December 2016

Mutation Rate Variation is a Primary Determinant of the Distribution of Allele Frequencies in Humans.

PLoS Genet 2016 Dec 15;12(12):e1006489. Epub 2016 Dec 15.

Department of Biology, Stanford University, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1006489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157949PMC
December 2016

Detection of human adaptation during the past 2000 years.

Science 2016 11 13;354(6313):760-764. Epub 2016 Oct 13.

Department of Genetics, Stanford University, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aag0776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182071PMC
November 2016

Genetic variation in MHC proteins is associated with T cell receptor expression biases.

Nat Genet 2016 09 1;48(9):995-1002. Epub 2016 Aug 1.

Department of Genetics, Stanford University, Stanford, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010864PMC
September 2016

Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila.

G3 (Bethesda) 2016 08 9;6(8):2505-16. Epub 2016 Aug 9.

Department of Molecular Genetics and Cell Biology, The University of Chicago, Illinois 60637

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/g3.116.028878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978903PMC
August 2016

msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.

PLoS One 2015 25;10(9):e0138030. Epub 2015 Sep 25.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America; Department of Statistics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138030PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583425PMC
May 2016

Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals.

Science 2016 May;352(6288):1009-13

Department of Genetics, Stanford University, Stanford, CA, USA. Department of Biology, Stanford University, Stanford, CA, USA. Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad8411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182070PMC
May 2016

RNA splicing is a primary link between genetic variation and disease.

Science 2016 Apr 28;352(6285):600-4. Epub 2016 Apr 28.

Department of Genetics, Stanford University, Stanford, CA, USA. Department of Biology, Stanford University, Stanford, CA, USA. Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad9417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182069PMC
April 2016

The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines.

PLoS One 2014 5;9(9):e107166. Epub 2014 Sep 5.

Department of Human Genetics, The University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156430PMC
February 2016

Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs.

PLoS Genet 2016 Jan 26;12(1):e1005793. Epub 2016 Jan 26.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727884PMC
January 2016

Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature.

PLoS Genet 2015 May 7;11(5):e1005216. Epub 2015 May 7.

Department of Human Genetics, The University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423863PMC
May 2015

Genomic variation. Impact of regulatory variation from RNA to protein.

Science 2015 Feb 18;347(6222):664-7. Epub 2014 Dec 18.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://www.sciencemag.org/cgi/doi/10.1126/science.1260793
Publisher Site
http://dx.doi.org/10.1126/science.1260793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507520PMC
February 2015

The genetic and mechanistic basis for variation in gene regulation.

PLoS Genet 2015 Jan 8;11(1):e1004857. Epub 2015 Jan 8.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
https://dx.doi.org/10.1371/journal.pgen.1004857
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1004857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287341PMC
January 2015

fastSTRUCTURE: variational inference of population structure in large SNP data sets.

Genetics 2014 Jun 2;197(2):573-89. Epub 2014 Apr 2.

Department of Genetics, Stanford University, Stanford, California 94305 Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, California 94305.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.114.164350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063916PMC
June 2014

The deleterious mutation load is insensitive to recent population history.

Nat Genet 2014 Mar 9;46(3):220-4. Epub 2014 Feb 9.

1] Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, USA. [2].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953611PMC
March 2014

The functional consequences of variation in transcription factor binding.

PLoS Genet 2014 Mar 6;10(3):e1004226. Epub 2014 Mar 6.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945204PMC
March 2014

Archaic humans: Four makes a party.

Nature 2014 Jan 18;505(7481):32-4. Epub 2013 Dec 18.

Departments of Genetics and Biology and the Howard Hughes Medical Institute, Stanford University, Stanford, California 94305-5120, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nature12847
Publisher Site
http://dx.doi.org/10.1038/nature12847DOI Listing
January 2014

Primate transcript and protein expression levels evolve under compensatory selection pressures.

Science 2013 Nov 17;342(6162):1100-4. Epub 2013 Oct 17.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1242379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994702PMC
November 2013

Inference of population splits and mixtures from genome-wide allele frequency data.

PLoS Genet 2012 15;8(11):e1002967. Epub 2012 Nov 15.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
https://dx.plos.org/10.1371/journal.pgen.1002967
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1002967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499260PMC
May 2013

Controls of nucleosome positioning in the human genome.

PLoS Genet 2012 15;8(11):e1003036. Epub 2012 Nov 15.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
https://dx.plos.org/10.1371/journal.pgen.1003036
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1003036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499251PMC
May 2013

The genetic architecture of adaptations to high altitude in Ethiopia.

PLoS Genet 2012 6;8(12):e1003110. Epub 2012 Dec 6.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1003110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516565PMC
May 2013

Genomics: ENCODE explained.

Nature 2012 Sep;489(7414):52-5

Howard Hughes Medical Institute and the Salk Institute for Biological Studies, La Jolla, California 92037, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/489052a
Publisher Site
http://dx.doi.org/10.1038/489052aDOI Listing
September 2012

Comment on "Widespread RNA and DNA sequence differences in the human transcriptome".

Science 2012 Mar;335(6074):1302; author reply 1302

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://www.sciencemag.org/cgi/doi/10.1126/science.1210484
Publisher Site
http://dx.doi.org/10.1126/science.1210484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207799PMC
March 2012

Haplotype variation and genotype imputation in African populations.

Genet Epidemiol 2011 Dec;35(8):766-80

Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.20626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568705PMC
December 2011

Whole-genome sequencing data offer insights into human demography.

Nat Genet 2011 Sep 28;43(10):923-5. Epub 2011 Sep 28.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.953DOI Listing
September 2011

False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions.

Bioinformatics 2011 Aug 19;27(15):2144-6. Epub 2011 Jun 19.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btr354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137225PMC
August 2011

Efficient counting of k-mers in DNA sequences using a bloom filter.

BMC Bioinformatics 2011 Aug 10;12:333. Epub 2011 Aug 10.

Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-12-333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166945PMC
August 2011

Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data.

Genome Res 2011 Mar 24;21(3):447-55. Epub 2010 Nov 24.

Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.112623.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044858PMC
March 2011

A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues.

PLoS Genet 2011 Feb 24;7(2):e1001316. Epub 2011 Feb 24.

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1001316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044686PMC
February 2011

Noisy splicing drives mRNA isoform diversity in human cells.

PLoS Genet 2010 Dec 9;6(12):e1001236. Epub 2010 Dec 9.

Department of Human Genetics, The University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1001236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000347PMC
December 2010

Adaptation - not by sweeps alone.

Nat Rev Genet 2010 Oct 14;11(10):665-7. Epub 2010 Sep 14.

Department of Human Genetics, Howard Hughes Medical Institute, University of Chicago, Illinois 60615, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrg2880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652788PMC
October 2010

How we are evolving.

Sci Am 2010 Oct;303(4):40-7

University of Chicago, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/scientificamerican1010-40DOI Listing
October 2010

Using environmental correlations to identify loci underlying local adaptation.

Genetics 2010 Aug 1;185(4):1411-23. Epub 2010 Jun 1.

Department of Evolution and Ecology and Center for Population Biology, University of California, Davis, Calfornia 95616, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.110.114819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927766PMC
August 2010

The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation.

Curr Biol 2010 Feb;20(4):R208-15

Department of Human Genetics, The University of Chicago, Room 507, 929 E. 58th St, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2009.11.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994553PMC
February 2010

Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data.

Bioinformatics 2009 Dec 6;25(24):3207-12. Epub 2009 Oct 6.

Department of Human Genetics, University of Chicago, 920 E. 58th St., CLSC 507, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btp579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788925PMC
December 2009

Characterizing natural variation using next-generation sequencing technologies.

Trends Genet 2009 Oct 2;25(10):463-71. Epub 2009 Oct 2.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2009.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994700PMC
October 2009

Inferring weak population structure with the assistance of sample group information.

Mol Ecol Resour 2009 Sep 1;9(5):1322-32. Epub 2009 Apr 1.

Department of Human Genetics, Department of Statistics, and Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853, USA, Environmental Research Institute, Department of Microbiology, University College Cork, Cork, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1755-0998.2009.02591.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518025PMC
September 2009

Revealing the architecture of gene regulation: the promise of eQTL studies.

Trends Genet 2008 Aug 1;24(8):408-15. Epub 2008 Jul 1.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2008.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583071PMC
August 2008

High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.

Science 2008 Mar 31;319(5868):1395-8. Epub 2008 Jan 31.

Department of Human Genetics, University of Chicago, 920 East 58th Street, Cummings Life Science Center, Chicago, IL 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1151851DOI Listing
March 2008

Adaptations to climate in candidate genes for common metabolic disorders.

PLoS Genet 2008 Feb;4(2):e32

Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.0040032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242814PMC
February 2008

Adaptive drool in the gene pool.

Nat Genet 2007 Oct;39(10):1188-90

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng1007-1188DOI Listing
October 2007

Adaptive evolution of conserved noncoding elements in mammals.

PLoS Genet 2007 Sep 18;3(9):1572-86. Epub 2007 Jul 18.

Department of Statistics, The University of Chicago, Chicago, Illinois, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.0030147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971121PMC
September 2007

Overcoming the winner's curse: estimating penetrance parameters from case-control data.

Am J Hum Genet 2007 Apr 16;80(4):605-15. Epub 2007 Feb 16.

Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/512821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852705PMC
April 2007

A worldwide survey of haplotype variation and linkage disequilibrium in the human genome.

Nat Genet 2006 Nov 22;38(11):1251-60. Epub 2006 Oct 22.

Department of Human Genetics, University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng1911DOI Listing
November 2006

Sequencing and analysis of Neanderthal genomic DNA.

Science 2006 Nov;314(5802):1113-8

U.S. Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1131412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583069PMC
November 2006

Clonal origin and evolution of a transmissible cancer.

Cell 2006 Aug;126(3):477-87

MRC/UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593932PMC
http://dx.doi.org/10.1016/j.cell.2006.05.051DOI Listing
August 2006

The effects of genotype-dependent recombination, and transmission asymmetry, on linkage disequilibrium.

Genetics 2006 Mar 30;172(3):2001-5. Epub 2005 Dec 30.

Department of Human Genetics, University of Chicago, Chicago, Illinois 60637.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.104.039271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456301PMC
March 2006

A map of recent positive selection in the human genome.

PLoS Biol 2006 Mar 7;4(3):e72. Epub 2006 Mar 7.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

View Article

Download full-text PDF

Source
https://dx.plos.org/10.1371/journal.pbio.0040072
Publisher Site
http://dx.doi.org/10.1371/journal.pbio.0040072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382018PMC
March 2006

A high-resolution survey of deletion polymorphism in the human genome.

Nat Genet 2006 Jan 4;38(1):75-81. Epub 2005 Dec 4.

Department of Human Genetics, The University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng1697DOI Listing
January 2006

Clines, clusters, and the effect of study design on the inference of human population structure.

PLoS Genet 2005 Dec 9;1(6):e70. Epub 2005 Dec 9.

Department of Human Genetics, Bioinformatics Program, and the Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
https://web.stanford.edu/group/rosenberglab/papers/clinesclu
Web Search
http://dx.plos.org/10.1371/journal.pgen.0010070
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.0010070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310579PMC
December 2005