Publications by authors named "Jonathan H Fox"

17Publications

Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease.

Mitochondrion 2019 07 20;47:318-329. Epub 2019 Mar 20.

Department of Veterinary Sciences, University of Wyoming, Laramie, WY 82070, USA. Electronic address:

View Article and Find Full Text PDF
July 2019

Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically.

Free Radic Biol Med 2018 05 4;120:317-329. Epub 2018 Apr 4.

Department of Veterinary Sciences, University of Wyoming, Laramie, WY 82070, United States. Electronic address:

View Article and Find Full Text PDF
May 2018

Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide-poisoned horses.

J Vet Diagn Invest 2018 Mar 4;30(2):280-285. Epub 2017 Dec 4.

Wyoming State Veterinary Laboratory, University of Wyoming, Laramie WY (Fox, Hildenbrand, O'Toole).

View Article and Find Full Text PDF
March 2018

Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality.

PLoS One 2016 9;11(9):e0162404. Epub 2016 Sep 9.

Department of Molecular Biology, University of Wyoming, Laramie, WY, 82071, United States of America.

View Article and Find Full Text PDF
August 2017

Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.

Redox Biol 2015 11;4:363-74. Epub 2015 Feb 11.

Department of Veterinary Sciences, University of Wyoming, 1174 Snowy Range Road, Laramie, WY 82070, USA; Neuroscience Graduate Program, University of Wyoming, 1174 Snowy Range Road, Laramie, WY 82070, USA. Electronic address:

View Article and Find Full Text PDF
June 2016

Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model.

Neurobiol Dis 2014 Nov 8;71:34-42. Epub 2014 Jul 8.

Department of Veterinary Sciences, University of Wyoming, Laramie, WY 82070, USA; Neuroscience Graduate Program, University of Wyoming, Laramie, WY 82070, USA. Electronic address:

View Article and Find Full Text PDF
November 2014

Iron accumulates in Huntington's disease neurons: protection by deferoxamine.

PLoS One 2013 11;8(10):e77023. Epub 2013 Oct 11.

Department of Veterinary Sciences and Neuroscience Graduate Program, University of Wyoming, Laramie, Wyoming, United States of America.

View Article and Find Full Text PDF
August 2014

A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse.

Proc Natl Acad Sci U S A 2007 Oct 9;104(42):16685-9. Epub 2007 Oct 9.

Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA 02129, USA.

View Article and Find Full Text PDF
October 2007

Mechanisms of copper ion mediated Huntington's disease progression.

PLoS One 2007 Mar 28;2(3):e334. Epub 2007 Mar 28.

Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America.

View Article and Find Full Text PDF
March 2007

Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1.

Hum Mol Genet 2005 Jan 17;14(2):179-89. Epub 2004 Nov 17.

Department of Neurology, MassGeneral Institute for Neurodegenerative Diseases, Massachusetts General Hospital and Harvard Medical School, Boston 02129, USA.

View Article and Find Full Text PDF
January 2005

Altered expression of transcripts for alpha-tubulin and an unidentified gene in the spinal cord of phenyl saligenin phosphate treated hens (Gallus gallus).

J Biochem Mol Toxicol 2003 ;17(5):263-71

Laboratory for Neurotoxicity Studies, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA.

View Article and Find Full Text PDF
June 2004