Jonathan D Mosley

Jonathan D Mosley

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Jonathan D Mosley

Jonathan D Mosley

Publications by authors named "Jonathan D Mosley"

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52Publications

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Clinical and genetic associations with prostacyclin response in pulmonary arterial hypertension.

Pulm Circ 2018 Oct-Dec;8(4):2045894018800544. Epub 2018 Aug 24.

1 Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1177/2045894018800544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134494PMC
August 2018

Clinical Features Associated With Nascent Left Ventricular Diastolic Dysfunction in a Population Aged 40 to 55 Years.

Am J Cardiol 2018 06 13;121(12):1552-1557. Epub 2018 Mar 13.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee.

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http://dx.doi.org/10.1016/j.amjcard.2018.02.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975107PMC
June 2018

Disease Heritability Studies Harness the Healthcare System to Achieve Massive Scale.

Cell 2018 06;173(7):1568-1570

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.cell.2018.05.053DOI Listing
June 2018

Benefit of Preemptive Pharmacogenetic Information on Clinical Outcome.

Clin Pharmacol Ther 2018 05 13;103(5):787-794. Epub 2018 Mar 13.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1002/cpt.1035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134843PMC
May 2018

Replication and fine-mapping of genetic predictors of lipid traits in African-Americans.

J Hum Genet 2017 Oct 25;62(10):895-901. Epub 2017 May 25.

Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1038/jhg.2017.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612856PMC
October 2017

Comparison of HLA allelic imputation programs.

PLoS One 2017 16;12(2):e0172444. Epub 2017 Feb 16.

Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172444PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312875PMC
September 2017

Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults.

Pharmacogenet Genomics 2017 07;27(7):247-254

aDepartment of Medicine bVanderbilt Translational and Clinical Cardiovascular Research Group cDepartment of Neurology dDepartment of Pediatrics eInstitute for Clinical and Translational Research fDepartment of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee gDepartment of General Oncology hDepartment of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, Texas iDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA jDepartment of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1097/FPC.0000000000000284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502740PMC
July 2017

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes.

Circ Cardiovasc Genet 2017 Apr;10(2)

From the Department of Medicine (J.D.M., M.B.S., Q.S.W., C.M.S., J.C.D., D.M.R.), Vanderbilt Epidemiology Center (T.L.E.), Department of Biomedical Informatics (L.B., J.C.D., D.M.R.), Department of Pharmacology (D.M.R.), Vanderbilt University, Nashville, TN; Division of Cardiology, University of Illinois at Chicago (D.D.); Essentia Institute of Rural Health, Duluth, MN (C.A.M.); Center for Biomedical Research Informatics, NorthShore University Health System, Evanston, IL (W.T.); School of Medicine (C.G.C.), School of Public Health (C.G.C.), and School of Nursing (C.G.C.), Johns Hopkins University, Baltimore, MD; Division of Medical Genetics, Department of Medicine (G.P.J.), Department of Genome Sciences (G.P.J.), Department of Biomedical Informatics (D.R.C.), Department of Medical Education (D.R.C.), University of Washington; Group Health Research Institute, Seattle, WA (E.B.L.); Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (I.J.K.); Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.A.P.); Biomedical Informatics Research Center (P.L.P.), Center for Human Genetics (M.H.B., J.G.L.), Marshfield Clinic Research Foundation, WI; and Department of Epidemiology and Biostatistics, University of California, San Francisco (J.S.W.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434456PMC
April 2017

Defining a Contemporary Ischemic Heart Disease Genetic Risk Profile Using Historical Data.

Circ Cardiovasc Genet 2016 Dec 25;9(6):521-530. Epub 2016 Oct 25.

From the Department of Medicine (J.D.M., S.L.v.D., Q.S.W., C.M.S., J.C.D., D.M.R.), Department of Pediatrics (S.L.v.D.), Vanderbilt Epidemiology Center (T.L.E.), Biomedical Informatics (L.B., J.C.D., D.M.R.), and Department of Pharmacology (D.M.R.), Vanderbilt University, Nashville, TN; Essentia Institute of Rural Health, Duluth, MN (C.A.M.); Center for Biomedical Research Informatics, North Shore University Health System, Evanston, IL (W.T.); Department of Health Policy and Management Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD (C.G.C.); Departments of Medicine (Medical Genetics) and Genome Sciences (G.P.J.) and Departments of Biomedical Informatics and Medical Education (D.R.C.), University of Washington, Seattle; Group Health Research Institute, Seattle, WA (E.B.L.); Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (I.J.K.); Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.A.P.); and Biomedical Informatics Research Center (P.L.P., J.G.L.) and Center for Human Genetics (M.H.B.), Marshfield Clinic Research Foundation, WI.

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177499PMC
December 2016

Finding a Needle in a QT Interval Big Data Haystack: The Role for Orthogonal Datasets.

J Am Coll Cardiol 2016 10;68(16):1765-1768

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1016/j.jacc.2016.08.012DOI Listing
October 2016

Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations.

PLoS One 2014 20;9(6):e100322. Epub 2014 Jun 20.

Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America; Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100322PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065041PMC
February 2015

Using systems approaches to address challenges for clinical implementation of pharmacogenomics.

Wiley Interdiscip Rev Syst Biol Med 2014 Mar-Apr;6(2):125-35. Epub 2013 Dec 6.

Department of Medicine, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1002/wsbm.1255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944797PMC
October 2014

Coordination versus solvation in Al(+)(benzene)(n) complexes studied with infrared spectroscopy.

J Phys Chem A 2014 Sep 25;118(35):7516-25. Epub 2014 Mar 25.

Department of Chemistry, University of Georgia , Athens, Georgia 30602, United States.

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http://dx.doi.org/10.1021/jp500778wDOI Listing
September 2014

Whole-exome sequencing in familial atrial fibrillation.

Eur Heart J 2014 Sep 11;35(36):2477-83. Epub 2014 Apr 11.

Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USA Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1285A MRB IV, Nashville 37323-6602, TN, USA.

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http://eurheartj.oxfordjournals.org/content/ehj/35/36/2477.f
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http://eurheartj.oxfordjournals.org/cgi/doi/10.1093/eurheart
Publisher Site
http://dx.doi.org/10.1093/eurheartj/ehu156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169871PMC
September 2014

Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression.

Cancer Res 2014 Sep 14;74(17):4762-71. Epub 2014 Jul 14.

Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio. Department of Genetics and Division of General Medical Sciences-Oncology, Case Western Reserve University, School of Medicine, Cleveland, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155007PMC
September 2014

Structural isomerization of the gas-phase 2-norbornyl cation revealed with infrared spectroscopy and computational chemistry.

Angew Chem Int Ed Engl 2014 Jun 7;53(23):5888-91. Epub 2014 May 7.

Department of Chemistry, University of Georgia, Athens, GA 30602 (USA) http://maduncan.myweb.uga.edu.

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http://dx.doi.org/10.1002/anie.201311326DOI Listing
June 2014

Validation and enhancement of a computable medication indication resource (MEDI) using a large practice-based dataset.

AMIA Annu Symp Proc 2013 16;2013:1448-56. Epub 2013 Nov 16.

Department of Biomedical Informatics, Vanderbilt University, Nashville, TN ; Department of Medicine, Vanderbilt University, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900157PMC
May 2014

QT variability during initial exposure to sotalol: experience based on a large electronic medical record.

Europace 2013 Dec 19;15(12):1791-7. Epub 2013 Jun 19.

Department of Medicine and Clinical Pharmacology, Vanderbilt University, 1285 Medical Research Building IV, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1093/europace/eut153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888125PMC
December 2013

IR spectroscopy of protonation in benzene-water nanoclusters: hydronium, zundel, and eigen at a hydrophobic interface.

J Am Chem Soc 2012 Aug 27;134(31):13046-55. Epub 2012 Jul 27.

Department of Chemistry, University of Georgia , Athens, Georgia 30602, United States.

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http://dx.doi.org/10.1021/ja3038245DOI Listing
August 2012

Intrinsic bias in breast cancer gene expression data sets.

BMC Cancer 2009 Jun 29;9:214. Epub 2009 Jun 29.

Department of Pharmacology, Division of General Medical Sciences-Oncology, Case Western Reserve University School of Medicine, Cleveland, USA.

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http://dx.doi.org/10.1186/1471-2407-9-214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711113PMC
June 2009

Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists.

BMC Med Genomics 2008 Apr 25;1:11. Epub 2008 Apr 25.

Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, USA.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
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http://dx.doi.org/10.1186/1755-8794-1-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396170PMC
April 2008

Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer.

Mol Cancer Ther 2007 Aug;6(8):2188-97

Department of Pharmacology, CWRU School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106-4965, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562754PMC
August 2007

Splice variants of mIAP1 have an enhanced ability to inhibit apoptosis.

Biochem Biophys Res Commun 2006 Sep 4;348(3):1174-83. Epub 2006 Aug 4.

Department of Pharmacology, Case School of Medicine, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.07.176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592129PMC
September 2006

Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease.

Am J Hum Genet 2002 May 25;70(5):1229-39. Epub 2002 Mar 25.

Channing Laboratory and Division of Pulmonary and Critical Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1086/340316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC447597PMC
May 2002

Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes.

Hum Mol Genet 2002 Mar;11(6):623-32

Channing Laboratory, Division of Pulmonary and Critical Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/hmg/11.6.623DOI Listing
March 2002