Publications by authors named "Jonas Halfvarson"

99Publications

Restorative Surgery Is More Common In Ulcerative Colitis Patients with a High Income: A Population-Based Study.

Dis Colon Rectum 2020 Dec 7;Publish Ahead of Print. Epub 2020 Dec 7.

Dept. of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden Dept. of Colorectal Surgery, Karolinska University Hospital, Stockholm, Sweden Division of Surgery, Danderyd Hospital, Stockholm, Sweden Clinical Epidemiology Division, Dept. of Medicine Solna, Karolinska Institutet, Stockholm, Sweden Dept. of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden Dept. of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden Dept. Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Dept. of Pediatrics, Örebro University Hospital, Örebro, Sweden Division of surgery, Dept. of Clinical and Experimental Medicine, Faulty of Health Sciences, Linköping.

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December 2020

Crohn's Disease Is Associated With Activation of Circulating Innate Lymphoid Cells.

Inflamm Bowel Dis 2020 Dec 9. Epub 2020 Dec 9.

Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

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December 2020

Reply.

Clin Gastroenterol Hepatol 2020 Aug 28. Epub 2020 Aug 28.

The Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York.

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August 2020

Untargeted metabolomics profiling and hemoglobin normalization for archived newborn dried blood spots from a refrigerated biorepository.

J Pharm Biomed Anal 2020 Nov 23;191:113574. Epub 2020 Aug 23.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, United States; The Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, NY, 10029, United States. Electronic address:

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November 2020

Genetic and shared environmental risk factors do not lead to eosinophil activation in healthy twins of IBD patients.

Scand J Gastroenterol 2020 Oct 20;55(10):1163-1170. Epub 2020 Aug 20.

Department of Medical Sciences, Gastroenterology Research Group, Uppsala University, Uppsala, Sweden.

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October 2020

Age, Inflammation, and Disease Location Are Critical Determinants of Intestinal Expression of SARS-CoV-2 Receptor and in Inflammatory Bowel Disease.

Gastroenterology 2020 Sep 12;159(3):1151-1154.e2. Epub 2020 May 12.

Translational Gastroenterology Unit, Nuffield Department of Medicine, Experimental Medicine Division, University of Oxford, John Radcliffe Hospital, Oxford, UK; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. Electronic address:

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September 2020

Colorectal cancer in Crohn's disease: a Scandinavian population-based cohort study.

Lancet Gastroenterol Hepatol 2020 05 14;5(5):475-484. Epub 2020 Feb 14.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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May 2020

Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study.

Lancet 2020 01;395(10218):123-131

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Orebro University Hospital, Orebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, UK; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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January 2020

A User's Guide to De-escalating Immunomodulator and Biologic Therapy in Inflammatory Bowel Disease.

Clin Gastroenterol Hepatol 2020 May 27;18(6):1336-1345. Epub 2019 Dec 27.

Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York.

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May 2020

Validating surgical procedure codes for inflammatory bowel disease in the Swedish National Patient Register.

BMC Med Inform Decis Mak 2019 11 11;19(1):217. Epub 2019 Nov 11.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77, Stockholm, Sweden.

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November 2019

Prognostic significance of faecal eosinophil granule proteins in inflammatory bowel disease.

Scand J Gastroenterol 2019 Oct 2;54(10):1237-1244. Epub 2019 Oct 2.

Department of Medical Sciences, Gastroenterology Research Group, Uppsala University, Uppsala, Sweden.

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October 2019

Inflammatory Bowel Disease and Parkinson's Disease: A Reply to Letter to the Editor of Shih-Wei Lai.

Inflamm Bowel Dis 2019 09;25(10):e127

Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

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September 2019

Alterations in the relative abundance of correlate with changes in fecal calprotectin in patients with ileal Crohn's disease: a longitudinal study.

Scand J Gastroenterol 2019 May 19;54(5):577-585. Epub 2019 May 19.

d Department of Gastroenterology, Faculty of Medicine and Health , Örebro University , Örebro , Sweden.

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May 2019

Changes in inflammatory bowel disease subtype during follow-up and over time in 44,302 patients.

Scand J Gastroenterol 2019 Jan 31;54(1):55-63. Epub 2019 Jan 31.

a Department of Clinical Science and Education , Södersjukhuset, Karolinska Institutet , Stockholm , Sweden.

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January 2019

Validating microscopic colitis (MC) in Swedish pathology registers.

Scand J Gastroenterol 2018 Dec 2;53(12):1469-1475. Epub 2019 Jan 2.

a Department of Paediatrics , Örebro University Hospital , Örebro , Sweden.

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December 2018

Work Loss Before and After Diagnosis of Crohn's Disease.

Inflamm Bowel Dis 2019 06;25(7):1237-1247

Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

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June 2019

Differential clustering of fecal and mucosa-associated microbiota in 'healthy' individuals.

J Dig Dis 2018 Dec;19(12):745-752

Department of Microbiology, Tumor and Cell Biology & Science for Life Laboratory, Karolinska Institute, Solna, Sweden.

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December 2018

The Management of Inflammatory Bowel Disease in Elderly: Current Evidence and Future Perspectives.

Inflamm Intest Dis 2018 Jul 26;2(4):189-199. Epub 2018 Jun 26.

Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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July 2018

Sick Leave and Disability Pension in Prevalent Patients With Crohn's Disease.

J Crohns Colitis 2018 Nov;12(12):1418-1428

Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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November 2018

Incidence, prevalence and clinical outcome of anaemia in inflammatory bowel disease: a population-based cohort study.

Aliment Pharmacol Ther 2018 09 1;48(6):638-645. Epub 2018 Aug 1.

Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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September 2018

Should we use vedolizumab as mono or combo therapy in ulcerative colitis?

Best Pract Res Clin Gastroenterol 2018 Feb - Apr;32-33:27-34. Epub 2018 May 12.

Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, SE 70182, Örebro, Sweden. Electronic address:

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September 2018

Association between inflammatory bowel disease and Parkinson's disease: seek and you shall find?

Gut 2019 01 18;68(1):175-176. Epub 2018 Jul 18.

Department of Gastroenterology, North Zealand University Hospital, Frederikssund, Denmark.

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January 2019

Gut Barrier Dysfunction-A Primary Defect in Twins with Crohn's Disease Predominantly Caused by Genetic Predisposition.

J Crohns Colitis 2018 Nov;12(10):1200-1209

Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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November 2018

Impact of thiopurines on the natural history and surgical outcome of ulcerative colitis: a cohort study.

Gut 2019 04 4;68(4):623-632. Epub 2018 Apr 4.

Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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April 2019

Inflammatory bowel disease registries for collection of patient iron parameters in Europe.

World J Gastroenterol 2018 Mar;24(10):1063-1071

Service d'hépato-gastroentérologie, CHU de Rouen-Hôpital Charles Nicolle, Rouen 76031, France.

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March 2018

Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease: a population-based study.

Gut 2019 02 10;68(2):218-225. Epub 2018 Jan 10.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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February 2019

Birth weight, sex, and celiac disease: a nationwide twin study.

Clin Epidemiol 2017 10;9:567-577. Epub 2017 Nov 10.

Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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November 2017

Incidence and Treatment of Patients Diagnosed With Inflammatory Bowel Diseases at 60 Years or Older in Sweden.

Gastroenterology 2018 02 2;154(3):518-528.e15. Epub 2017 Nov 2.

Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden; Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Department of Pediatric Gastroenterology and Nutrition, Sachs' Children and Youth Hospital, Stockholm, Sweden.

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February 2018

Resilience to stress and risk of gastrointestinal infections.

Eur J Public Health 2018 04;28(2):364-369

Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.

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April 2018

Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles.

PLoS One 2017 5;12(10):e0186142. Epub 2017 Oct 5.

Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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November 2017

Cost-utility of biological treatment sequences for luminal Crohn's disease in Europe.

Expert Rev Pharmacoecon Outcomes Res 2017 Dec 28;17(6):597-606. Epub 2017 Apr 28.

a Department of Health Economics , Corvinus University of Budapest , Budapest , Hungary.

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December 2017

Elevated fecal peptidase D at onset of colitis in Galphai2-/- mice, a mouse model of IBD.

PLoS One 2017 21;12(3):e0174275. Epub 2017 Mar 21.

School of Medical Sciences, Faculty of Medicine and Health, University of Örebro, Örebro, Sweden.

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September 2017

Stress resilience and the risk of inflammatory bowel disease: a cohort study of men living in Sweden.

BMJ Open 2017 01 27;7(1):e014315. Epub 2017 Jan 27.

Department of Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.

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January 2017

Clinical implications of assay specific differences in f-calprotectin when monitoring inflammatory bowel disease activity over time.

Scand J Gastroenterol 2017 Mar 24;52(3):344-350. Epub 2016 Nov 24.

a Dept of Gastroenterology, Faculty of Medicine and Health , Örebro University , Örebro , Sweden.

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March 2017

Validating inflammatory bowel disease (IBD) in the Swedish National Patient Register and the Swedish Quality Register for IBD (SWIBREG).

Scand J Gastroenterol 2017 Feb 31;52(2):216-221. Epub 2016 Oct 31.

a Department of Medical Epidemiology and Biostatistics , Karolinska Institutet , Stockholm , Sweden.

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February 2017

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Nat Commun 2016 08 9;7:12342. Epub 2016 Aug 9.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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August 2016

Heritability of non-HLA genetics in coeliac disease: a population-based study in 107 000 twins.

Gut 2016 11 20;65(11):1793-1798. Epub 2016 May 20.

Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

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November 2016

Physical Fitness in Adolescence and Subsequent Inflammatory Bowel Disease Risk.

Clin Transl Gastroenterol 2015 Nov 5;6:e121. Epub 2015 Nov 5.

Clinical Epidemiology and Biostatistics, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

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November 2015

Polymorphism in the NLRP3 inflammasome-associated EIF2AK2 gene and inflammatory bowel disease.

Mol Med Rep 2015 Jun 21;11(6):4579-84. Epub 2015 Jan 21.

Department of Clinical Medicine, School of Health and Medical Sciences, Örebro University, Örebro SE‑70182, Sweden.

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June 2015

Costs and resource utilization for diagnosis and treatment during the initial year in a European inflammatory bowel disease inception cohort: an ECCO-EpiCom Study.

Inflamm Bowel Dis 2015 Jan;21(1):121-31

1Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark; 2Department of Public Health, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel; 3Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia; 4Private Practice, Nicosia, Cyprus; 5IBD Center ISCARE, Charles University, Prague, Czech Republic; 6Department of Gastroenterology, Hospital České Budějovice, České Budějovice, Czech Republic; 7Department of Medicine, Amager Hospital, Amager, Denmark; 8Department of Medicine, Herning Central Hospital, Herning, Denmark; 9Medical Department, Viborg Regional Hospital, Viborg, Denmark; 10Organ Center, Hospital of Southern Jutland, Aabenraa, Denmark; 11Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark; 12Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Arhus, Denmark; 13Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark; 14Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia; 15Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands; 16Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; 17First Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece; 18Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland; 19First Department of Medicine, Semmelweis University, Budapest, Hungary; 20Department of Gastroenterology, Adelaide and Meath Hospital, TCD, Dublin, Ireland; 21Department of Gastroenterology and Hepatology, Soroka Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel; 22U.O. di Gastroenterologia e Endoscopia Digestiva, Az.Ospedaliera Ospedale Maggiore di Crema, Crema, Italy; 23EpiCom Northern Italy centre based in Crema a

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January 2015

The history of genetics in inflammatory bowel disease.

Ann Gastroenterol 2014 ;27(4):294-303

Department of Internal medicine, Division of Gastroenterology, Örebro University Hospital and School of Health and Medical Sciences, Örebro University, Örebro (Jonas Halfvarson), Sweden.

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January 2014

Temporal trends in non-stricturing and non-penetrating behaviour at diagnosis of Crohn's disease in Örebro, Sweden: a population-based retrospective study.

J Crohns Colitis 2014 Dec 10;8(12):1653-60. Epub 2014 Aug 10.

Department of Internal Medicine, Division of Gastroenterology, Örebro University Hospital, Örebro, Sweden; School of Health and Medical Sciences, Örebro University, Örebro, Sweden. Electronic address:

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December 2014

Initial disease course and treatment in an inflammatory bowel disease inception cohort in Europe: the ECCO-EpiCom cohort.

Inflamm Bowel Dis 2014 Jan;20(1):36-46

1Medical Section, Digestive Disease Centre, Medical Section, Herlev University Hospital, Copenhagen, Denmark; 2Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia; 3Nicosia Private Practice, Nicosia, Cyprus; 4IBD Center ISCARE, Charles University, Prague, Czech Republic; 5Gastroenterology Department, Hospital České Budějovice, České Budějovice, Czech Republic; 6Department of Medicine, Amager Hospital, Amager, Denmark; 7Department of Medicine, Herning Central Hospital, Herning, Denmark; 8Medical Department, Viborg Regional Hospital, Viborg, Denmark; 9Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; 10Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark; 11Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Arhus, Denmark; 12Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark; 13Division of Endocrinology and Gastroenterology, Tartu University Hospital, Tartu, Estonia; 14Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands; 15Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; 161st Division of Internal Medicine and Hepato-Gastroenterology Unit, University Hospital, Ioannina, Greece; 17Medical Department, Dronning Ingrids Hospital, Nuuk, Greenland; 18Department of Medicine, Csolnoky F. Province Hospital, Veszprem, Hungary; 19Department of Gastroenterology, Adelaide and Meath Hospital, Trinity College of Dublin, Dublin, Ireland; 20Department of Gastroenterology and Hepatology, Soroka Medical Center and Ben Gurion University of the Negev, Beer Sheva, Israel; 21U.O. Gastroenterologia, Azienda Ospedaliera, Università di Padova, Padova, Italy; 22EpiCom Northern Italy Centre based in Crema & Cremona, Padova and Reggio Emilia, Italy; 23UO Medicina 3° e Gastroenterologia, Azie

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January 2014

Colorectal cancer in patients with inflammatory bowel disease: can we predict risk?

World J Gastroenterol 2012 Aug;18(31):4091-4

Medical Department, Sygehus Sønderjylland Aabenraa, DK-6200 Aabenraa, Denmark.

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August 2012