John Wrangle

John Wrangle

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John Wrangle

John Wrangle

Publications by authors named "John Wrangle"

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SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.

Sci Adv 2019 Sep 18;5(9):eaax6352. Epub 2019 Sep 18.

Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1126/sciadv.aax6352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750908PMC
September 2019

The clinical implications of immunogenomics in colorectal cancer: A path for precision medicine.

Cancer 2018 04 9;124(8):1650-1659. Epub 2018 Jan 9.

Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1002/cncr.31214DOI Listing
April 2018

IL-2 and Beyond in Cancer Immunotherapy.

J Interferon Cytokine Res 2018 02;38(2):45-68

2 Department of Surgery, Medical University of South Carolina , Charleston, South Carolina.

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http://dx.doi.org/10.1089/jir.2017.0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815463PMC
February 2018

Inducible Enhancement of T Cell Function and Anti-tumor Activity after Adoptive Transfer.

Mol Ther 2017 09 19;25(9):1995-1996. Epub 2017 Aug 19.

Departments of Surgery and Microbiology and Immunology, 86 Jonathan Lucas Street, Hollings Cancer Center Room 506, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589154PMC
September 2017

Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.

Cancer Immunol Immunother 2017 Jun 9;66(6):737-751. Epub 2017 Mar 9.

Departments of Surgery, and Microbiology and Immunology, Medical University of South Carolina, 86 Jonathan Lucas Street, Hollings Cancer Center Room 506, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1007/s00262-017-1965-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679708PMC
June 2017

First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.

N Engl J Med 2017 06;376(25):2415-2426

From the Ohio State University Comprehensive Cancer Center, Columbus (D.P.C.); LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf (M.R.), and Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.) - both in Germany; Hospital Universitario Doce de Octubre, Centro Nacional de Investigaciones Oncológicas and Universidad Complutense, Madrid (L.P.-A., J.C.J.), Vall d'Hebron University Hospital, Barcelona (E.F.), and Hospital Universitario Insular de Gran Canaria, Las Palmas (D.R.-A.) - all in Spain; H. Lee Moffitt Cancer Center, Tampa, FL (B.C.); Vanderbilt University Medical Center, Nashville (L. Horn); Antoni van Leeuwenhoek Ziekenhuis, Amsterdam (M.M.H.), and University of Groningen, Universitair Medisch Centrum Groningen, Groningen (T.J.N.H.) - both in the Netherlands; Prof. Dr. Ion Chiricuta Institute of Oncology and University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania (T.-E.C.); Baptist Health Lexington, Lexington, KY (F.B.); Duke University, Durham, NC (N.R.); Lehigh Valley Health Network, Allentown (S.N.), Fox Chase Cancer Center, Philadelphia (H.B.), and University of Pittsburgh Medical Center Cancer Center, Pittsburgh (L.C.V., M.A.S.) - all in Pennsylvania; Juravinski Cancer Centre, Hamilton, ON, Canada (R.J.); Oncology Department, Lausanne University Hospital, Lausanne, Switzerland (S.P.); Santa Maria Hospital, Terni, Italy (E.M.); Hollings Cancer Center, Charleston, SC (J.M.W.); Department of Thoracic-Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston (G.R.B.); Klinika Pneumologie a Hrudní Chirurgie, Nemocnice Na Bulovce, Prague, Czech Republic (L. Havel, J.K.); and Bristol-Myers Squibb, Princeton, NJ (H.C., W.J.G., P.B., A.C.C.).

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http://dx.doi.org/10.1056/NEJMoa1613493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487310PMC
June 2017

β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.

JCI Insight 2017 Apr 20;2(8). Epub 2017 Apr 20.

Department of Microbiology and Immunology, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina, USA.

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http://dx.doi.org/10.1172/jci.insight.90547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396523PMC
April 2017

Imaging in Advanced Non-Small Cell Lung Cancer: A Medical Oncology Perspective.

J Thorac Imaging 2016 Jul;31(4):238-42

Department of Medicine, Division of Hematology/Oncology, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1097/RTI.0000000000000219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461391PMC
July 2016

Harnessing the IL-7/IL-7Rα axis to improve tumor immunotherapy.

Oncoimmunology 2016 May 19;5(5):e1122865. Epub 2016 Jan 19.

Department of Surgery, Medical University of South Carolina, Charleston, SC; Department of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1080/2162402X.2015.1122865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910714PMC
May 2016

Neutrophil-to-lymphocyte ratio and overall survival in all sites of head and neck squamous cell carcinoma.

Head Neck 2016 04 28;38 Suppl 1:E1068-74. Epub 2015 Sep 28.

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1002/hed.24159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909151PMC
April 2016

Molecularly targeted therapies in non-small-cell lung cancer annual update 2014.

J Thorac Oncol 2015 Jan;10(1 Suppl 1):S1-63

*Department of Medical Oncology, Washington University School of Medicine, Saint Louis, Missouri; Departments of †Medical Oncology and ‡Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts; §Department of Medical Oncology, University of Colorado School of Medicine and University of Colorado Cancer Center, Aurora, Colorado; ‖UCLA Santa Monica Hematology Oncology, Santa Monica, California; ¶Division of Hematology-Oncology, Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas; #Department of Medical Oncology, Yale School of Medicine and Cancer Center, New Haven, Connecticut; **Massachusetts General Hospital Cancer Center, Boston, Massachusetts; ††Department of Oncology, The University of Chicago Medicine, Chicago, Illinois; ‡‡Division of Hematology-Oncology, Vanderbilt University Medical Center, Nashville, Tennessee; §§Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia; ‖‖Memorial Sloan-Kettering Cancer Center, New York, New York; ¶¶Division of Hematology-Oncology, Medical University of South Carolina, Charleston, South Carolina; ##Sarah Cannon Research Institute, Nashville, Tennessee; ***The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; †††Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas; and ‡‡‡Division of Medical Oncology, University of Colorado Denver School of Medicine, Denver, Colorado.

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http://dx.doi.org/10.1097/JTO.0000000000000405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346098PMC
January 2015

Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer.

Clin Cancer Res 2014 Apr 31;20(7):1856-64. Epub 2014 Jan 31.

Authors' Affiliations: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium; MDxHealth Inc, Irvine, California; Shinshu University School of Medicine, Asahi, Matsumoto, Nagano, Japan; and Lovelace Respiratory Research Institute, Albuquerque, New Mexico.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-2109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019442PMC
April 2014

CpG methylation as a tool to characterize cell-free Kaposi sarcoma herpesvirus DNA.

J Infect Dis 2012 Apr 22;205(7):1095-9. Epub 2012 Feb 22.

Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1093/infdis/jis032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295606PMC
April 2012

Ha sentido sola? Culturally competent screening for intimate partner violence in Latina women.

J Womens Health (Larchmt) 2008 Mar;17(2):261-8

Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://www.liebertpub.com/doi/10.1089/jwh.2007.0394
Publisher Site
http://dx.doi.org/10.1089/jwh.2007.0394DOI Listing
March 2008

Chemoprevention of squamous cell carcinoma of the head and neck.

Curr Opin Oncol 2007 May;19(3):180-7

Winship Cancer Institute/Emory University, Atlanta, Georgia 30322, USA.

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https://insights.ovid.com/crossref?an=00001622-200705000-000
Publisher Site
http://dx.doi.org/10.1097/CCO.0b013e3280f01026DOI Listing
May 2007