John Whittaker

John Whittaker

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John Whittaker

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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 Jun;51(6):1067

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-019-0438-3DOI Listing
June 2019

Fermentation Products That Mitigate Foodborne in Cattle and Poultry.

Front Vet Sci 2019 10;6:107. Epub 2019 Apr 10.

Department of Biomedical Sciences, Iowa State University College of Medicine, Ames, IA, United States.

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http://dx.doi.org/10.3389/fvets.2019.00107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467977PMC
April 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

A Hierarchical Model To Understand the Processing of Polysaccharides/Protein-Based Films in Ionic Liquids.

Biomacromolecules 2018 10 5;19(10):3970-3982. Epub 2018 Sep 5.

Department of Physics and Astronomy, Department of Biomedical Engineering , Rowan University , Glassboro , New Jersey 08028 , United States.

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http://dx.doi.org/10.1021/acs.biomac.8b00903DOI Listing
October 2018

Computational and experimental analysis of short peptide motifs for enzyme inhibition.

PLoS One 2017 15;12(8):e0182847. Epub 2017 Aug 15.

Department of Chemistry, Rutgers University-Camden, Camden, New Jersey, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182847PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557489PMC
October 2017

Impact of Phosphorylation and Pseudophosphorylation on the Early Stages of Aggregation of the Microtubule-Associated Protein Tau.

J Phys Chem B 2017 03 24;121(9):2095-2103. Epub 2017 Feb 24.

Department of Physics and ‡Center for Computational and Integrative Biology, Rutgers University-Camden , Camden, New Jersey 08102, United States.

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http://dx.doi.org/10.1021/acs.jpcb.7b00194DOI Listing
March 2017

Intestinal Enterobacteriaceae that Protect Nematodes from the Effects of Benzimidazoles.

J Bacteriol Parasitol 2016 Oct 31;7(5). Epub 2016 Oct 31.

Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA, USA.

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https://www.omicsonline.org/open-access/intestinal-enterobac
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http://dx.doi.org/10.4172/2155-9597.1000294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215066PMC
October 2016

Resonance control of mid-infrared metamaterials using arrays of split-ring resonator pairs.

Nanotechnology 2016 Feb 11;27(5):055303. Epub 2016 Jan 11.

National Graphene Institute, University of Manchester, Oxford Road, Manchester M13 9PL, UK.

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http://dx.doi.org/10.1088/0957-4484/27/5/055303DOI Listing
February 2016

Early tranexamic acid administration: A protective effect on gut barrier function following ischemia/reperfusion injury.

J Trauma Acute Care Surg 2015 Dec;79(6):1015-22

From the Marian and Michael Ilitch Department of Surgery (M.E.D., L.N.D., D.M.L., J.R.W.), and Department of Chemical Engineering (C.W.M.), Wayne State University, Detroit, Michigan.

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http://dx.doi.org/10.1097/TA.0000000000000703DOI Listing
December 2015

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Authors:
Daniel I Swerdlow David Preiss Karoline B Kuchenbaecker Michael V Holmes Jorgen E L Engmann Tina Shah Reecha Sofat Stefan Stender Paul C D Johnson Robert A Scott Maarten Leusink Niek Verweij Stephen J Sharp Yiran Guo Claudia Giambartolomei Christina Chung Anne Peasey Antoinette Amuzu KaWah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos Yun R Li Gordon Lowe John Gallacher Marlene C W Stewart Ioanna Tzoulaki Sarah G Buxbaum Daphne L van der A Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Urszula Stepaniak Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Fabrizio Veglia Ian Ford J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Pim A de Jong Ale Algra Wilko Spiering Anke H Maitland-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Charles B Eaton Jennifer G Robinson David Duggan John Kjekshus John R Downs Antonio M Gotto Anthony C Keech Roberto Marchioli Gianni Tognoni Peter S Sever Neil R Poulter David D Waters Terje R Pedersen Pierre Amarenco Haruo Nakamura John J V McMurray James D Lewsey Daniel I Chasman Paul M Ridker Aldo P Maggioni Luigi Tavazzi Kausik K Ray Sreenivasa Rao Kondapally Seshasai JoAnn E Manson Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Pamela J Schreiner Myriam Fornage David S Siscovick Mary Cushman Meena Kumari Nick J Wareham W M Monique Verschuren Susan Redline Sanjay R Patel John C Whittaker Anders Hamsten Joseph A Delaney Caroline Dale Tom R Gaunt Andrew Wong Diana Kuh Rebecca Hardy Sekar Kathiresan Berta A Castillo Pim van der Harst Eric J Brunner Anne Tybjaerg-Hansen Michael G Marmot Ronald M Krauss Michael Tsai Josef Coresh Ronald C Hoogeveen Bruce M Psaty Leslie A Lange Hakon Hakonarson Frank Dudbridge Steve E Humphries Philippa J Talmud Mika Kivimäki Nicholas J Timpson Claudia Langenberg Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Alex P Reiner Brendan J Keating Aroon D Hingorani Naveed Sattar

Lancet 2015 Jan 24;385(9965):351-61. Epub 2014 Sep 24.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1016/S0140-6736(14)61183-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322187PMC
January 2015

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits.

Int J Epidemiol 2014 Dec 5;43(6):1781-90. Epub 2014 Sep 5.

Faculty of Epidemiology and Population Health, Centre for Statistical Methodology and Bloomsbury Centre for Genetic Epidemiology and Statistics, London School of Hygiene and Tropical Medicine, London, UK, Department of Epidemiology and Public Health, University College London, London, UK, MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol, UK, Genetics, R & D, GlaxoSmithKline, Stevenage, UK, Division of Health Sciences, University of Warwick, Warwick, Coventry, UK, Center for Applied Genomics, Abramson Research Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA and Institute of Cardiovascular Science, University College London, London, UK Faculty of Epidemiology and Population Health, Centre for Statistical Methodology and Bloomsbury Centre for Genetic Epidemiology and Statistics, London School of Hygiene and Tropical Medicine, London, UK, Department of Epidemiology and Public Health, University College London, London, UK, MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol, UK, Genetics, R & D, GlaxoSmithKline, Stevenage, UK, Division of Health Sciences, University of Warwick, Warwick, Coventry, UK, Center for Applied Genomics, Abramson Research Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA and Institute of Cardiovascular Science, University College London, London, UK Faculty of Epidemiology and Population Health, Centre for Statistical Methodology and Bloomsbury Centre for Genetic Epidemiology and Statistics, London School of Hygiene and Tropical Medicine, London, UK, Department of Epidemiology and Public Health, University College London, London, UK, MRC Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol, UK, Genetics, R & D, GlaxoSmithKline, Stevenage, UK, Division of Health Sciences, University of Warwick, Warwick, Coventry, UK, Center for Applied Genomics

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http://dx.doi.org/10.1093/ije/dyu187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276061PMC
December 2014

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.

Authors:
Karani S Vimaleswaran Alana Cavadino Diane J Berry Rolf Jorde Aida Karina Dieffenbach Chen Lu Alexessander Couto Alves Hiddo J Lambers Heerspink Emmi Tikkanen Joel Eriksson Andrew Wong Massimo Mangino Kathleen A Jablonski Ilja M Nolte Denise K Houston Tarunveer Singh Ahluwalia Peter J van der Most Dorota Pasko Lina Zgaga Elisabeth Thiering Veronique Vitart Ross M Fraser Jennifer E Huffman Rudolf A de Boer Ben Schöttker Kai-Uwe Saum Mark I McCarthy Josée Dupuis Karl-Heinz Herzig Sylvain Sebert Anneli Pouta Jaana Laitinen Marcus E Kleber Gerjan Navis Mattias Lorentzon Karen Jameson Nigel Arden Jackie A Cooper Jayshree Acharya Rebecca Hardy Olli Raitakari Samuli Ripatti Liana K Billings Jari Lahti Clive Osmond Brenda W Penninx Lars Rejnmark Kurt K Lohman Lavinia Paternoster Ronald P Stolk Dena G Hernandez Liisa Byberg Emil Hagström Håkan Melhus Erik Ingelsson Dan Mellström Osten Ljunggren Ioanna Tzoulaki Stela McLachlan Evropi Theodoratou Carla M T Tiesler Antti Jula Pau Navarro Alan F Wright Ozren Polasek James F Wilson Igor Rudan Veikko Salomaa Joachim Heinrich Harry Campbell Jacqueline F Price Magnus Karlsson Lars Lind Karl Michaëlsson Stefania Bandinelli Timothy M Frayling Catharina A Hartman Thorkild I A Sørensen Stephen B Kritchevsky Bente Lomholt Langdahl Johan G Eriksson Jose C Florez Tim D Spector Terho Lehtimäki Diana Kuh Steve E Humphries Cyrus Cooper Claes Ohlsson Winfried März Martin H de Borst Meena Kumari Mika Kivimaki Thomas J Wang Chris Power Hermann Brenner Guri Grimnes Pim van der Harst Harold Snieder Aroon D Hingorani Stefan Pilz John C Whittaker Marjo-Riitta Järvelin Elina Hyppönen

Lancet Diabetes Endocrinol 2014 Sep 25;2(9):719-29. Epub 2014 Jun 25.

Population, Policy and Practice, UCL Institute of Child Health, London, UK; School of Population Health, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(14)70113-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582411PMC
September 2014

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Authors:
Michael V Holmes Caroline E Dale Luisa Zuccolo Richard J Silverwood Yiran Guo Zheng Ye David Prieto-Merino Abbas Dehghan Stella Trompet Andrew Wong Alana Cavadino Dagmar Drogan Sandosh Padmanabhan Shanshan Li Ajay Yesupriya Maarten Leusink Johan Sundstrom Jaroslav A Hubacek Hynek Pikhart Daniel I Swerdlow Andrie G Panayiotou Svetlana A Borinskaya Chris Finan Sonia Shah Karoline B Kuchenbaecker Tina Shah Jorgen Engmann Lasse Folkersen Per Eriksson Fulvio Ricceri Olle Melander Carlotta Sacerdote Dale M Gamble Sruti Rayaprolu Owen A Ross Stela McLachlan Olga Vikhireva Ivonne Sluijs Robert A Scott Vera Adamkova Leon Flicker Frank M van Bockxmeer Christine Power Pedro Marques-Vidal Tom Meade Michael G Marmot Jose M Ferro Sofia Paulos-Pinheiro Steve E Humphries Philippa J Talmud Irene Mateo Leach Niek Verweij Allan Linneberg Tea Skaaby Pieter A Doevendans Maarten J Cramer Pim van der Harst Olaf H Klungel Nicole F Dowling Anna F Dominiczak Meena Kumari Andrew N Nicolaides Cornelia Weikert Heiner Boeing Shah Ebrahim Tom R Gaunt Jackie F Price Lars Lannfelt Anne Peasey Ruzena Kubinova Andrzej Pajak Sofia Malyutina Mikhail I Voevoda Abdonas Tamosiunas Anke H Maitland-van der Zee Paul E Norman Graeme J Hankey Manuela M Bergmann Albert Hofman Oscar H Franco Jackie Cooper Jutta Palmen Wilko Spiering Pim A de Jong Diana Kuh Rebecca Hardy Andre G Uitterlinden M Arfan Ikram Ian Ford Elina Hyppönen Osvaldo P Almeida Nicholas J Wareham Kay-Tee Khaw Anders Hamsten Lise Lotte N Husemoen Anne Tjønneland Janne S Tolstrup Eric Rimm Joline W J Beulens W M Monique Verschuren N Charlotte Onland-Moret Marten H Hofker S Goya Wannamethee Peter H Whincup Richard Morris Astrid M Vicente Hugh Watkins Martin Farrall J Wouter Jukema James Meschia L Adrienne Cupples Stephen J Sharp Myriam Fornage Charles Kooperberg Andrea Z LaCroix James Y Dai Matthew B Lanktree David S Siscovick Eric Jorgenson Bonnie Spring Josef Coresh Yun R Li Sarah G Buxbaum Pamela J Schreiner R Curtis Ellison Michael Y Tsai Sanjay R Patel Susan Redline Andrew D Johnson Ron C Hoogeveen Hakon Hakonarson Jerome I Rotter Eric Boerwinkle Paul I W de Bakker Mika Kivimaki Folkert W Asselbergs Naveed Sattar Debbie A Lawlor John Whittaker George Davey Smith Kenneth Mukamal Bruce M Psaty James G Wilson Leslie A Lange Ajna Hamidovic Aroon D Hingorani Børge G Nordestgaard Martin Bobak David A Leon Claudia Langenberg Tom M Palmer Alex P Reiner Brendan J Keating Frank Dudbridge Juan P Casas

BMJ 2014 Jul 10;349:g4164. Epub 2014 Jul 10.

Genetic Epidemiology Group, Institute of Cardiovascular Science, Department of Epidemiology and Public Health, University College London, UK Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091648PMC
http://dx.doi.org/10.1136/bmj.g4164DOI Listing
July 2014

Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores.

Genet Epidemiol 2014 Jan 23;38(1):72-83. Epub 2013 Nov 23.

Department of Non-Communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1002/gepi.21777DOI Listing
January 2014

A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy.

Am J Gastroenterol 2014 Jan 24;109(1):76-84. Epub 2013 Dec 24.

1] Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Division of Surgery and Cancer, Imperial College London, London, UK [2] Present address: Division of Women's Health, King's College London, London, UK.

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http://dx.doi.org/10.1038/ajg.2013.406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887577PMC
January 2014

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thromb Haemost 2013 Nov 29;110(5):995-1003. Epub 2013 Aug 29.

MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.

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http://dx.doi.org/10.1160/TH13-02-0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067543PMC
November 2013

The impact of targeting all elderly persons in England and Wales for yearly influenza vaccination: excess mortality due to pneumonia or influenza and time trend study.

BMJ Open 2013 Aug 1;3(8). Epub 2013 Aug 1.

Department of Infectious Disease Epidemiology, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2013-002743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733298PMC
August 2013

Comparison of statistical tests for association between rare variants and binary traits.

PLoS One 2012 9;7(8):e42530. Epub 2012 Aug 9.

Quantitative Sciences, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042530PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415421PMC
April 2013

Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.

Circ Cardiovasc Genet 2013 Apr 16;6(2):163-70. Epub 2013 Mar 16.

Genetic Epidemiology Group, Research Department of Epidemiology and Public Health, UCL Institute of Epidemiology & Health Care, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGENETICS.112.964254DOI Listing
April 2013

Recurrent cotyledonoid dissecting leiomyoma of the uterus.

Int J Gynecol Pathol 2013 Mar;32(2):215-20

Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202-5120, USA.

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http://dx.doi.org/10.1097/PGP.0b013e318257dff4DOI Listing
March 2013

Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D.

PLoS One 2012 21;7(5):e37465. Epub 2012 May 21.

Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037465PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357436PMC
December 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Authors:
Folkert W Asselbergs Yiran Guo Erik P A van Iperen Suthesh Sivapalaratnam Vinicius Tragante Matthew B Lanktree Leslie A Lange Berta Almoguera Yolande E Appelman John Barnard Jens Baumert Amber L Beitelshees Tushar R Bhangale Yii-Der Ida Chen Tom R Gaunt Yan Gong Jemma C Hopewell Toby Johnson Marcus E Kleber Taimour Y Langaee Mingyao Li Yun R Li Kiang Liu Caitrin W McDonough Matthijs F L Meijs Rita P S Middelberg Kiran Musunuru Christopher P Nelson Jeffery R O'Connell Sandosh Padmanabhan James S Pankow Nathan Pankratz Suzanne Rafelt Ramakrishnan Rajagopalan Simon P R Romaine Nicholas J Schork Jonathan Shaffer Haiqing Shen Erin N Smith Sam E Tischfield Peter J van der Most Jana V van Vliet-Ostaptchouk Niek Verweij Kelly A Volcik Li Zhang Kent R Bailey Kristian M Bailey Florianne Bauer Jolanda M A Boer Peter S Braund Amber Burt Paul R Burton Sarah G Buxbaum Wei Chen Rhonda M Cooper-Dehoff L Adrienne Cupples Jonas S deJong Christian Delles David Duggan Myriam Fornage Clement E Furlong Nicole Glazer John G Gums Claire Hastie Michael V Holmes Thomas Illig Susan A Kirkland Mika Kivimaki Ronald Klein Barbara E Klein Charles Kooperberg Kandice Kottke-Marchant Meena Kumari Andrea Z LaCroix Laya Mallela Gurunathan Murugesan Jose Ordovas Willem H Ouwehand Wendy S Post Richa Saxena Hubert Scharnagl Pamela J Schreiner Tina Shah Denis C Shields Daichi Shimbo Sathanur R Srinivasan Ronald P Stolk Daniel I Swerdlow Herman A Taylor Eric J Topol Elina Toskala Joost L van Pelt Jessica van Setten Salim Yusuf John C Whittaker A H Zwinderman Sonia S Anand Anthony J Balmforth Gerald S Berenson Connie R Bezzina Bernhard O Boehm Eric Boerwinkle Juan P Casas Mark J Caulfield Robert Clarke John M Connell Karen J Cruickshanks Karina W Davidson Ian N M Day Paul I W de Bakker Pieter A Doevendans Anna F Dominiczak Alistair S Hall Catharina A Hartman Christian Hengstenberg Hans L Hillege Marten H Hofker Steve E Humphries Gail P Jarvik Julie A Johnson Bernhard M Kaess Sekar Kathiresan Wolfgang Koenig Debbie A Lawlor Winfried März Olle Melander Braxton D Mitchell Grant W Montgomery Patricia B Munroe Sarah S Murray Stephen J Newhouse N Charlotte Onland-Moret Neil Poulter Bruce Psaty Susan Redline Stephen S Rich Jerome I Rotter Heribert Schunkert Peter Sever Alan R Shuldiner Roy L Silverstein Alice Stanton Barbara Thorand Mieke D Trip Michael Y Tsai Pim van der Harst Ellen van der Schoot Yvonne T van der Schouw W M Monique Verschuren Hugh Watkins Arthur A M Wilde Bruce H R Wolffenbuttel John B Whitfield G Kees Hovingh Christie M Ballantyne Cisca Wijmenga Muredach P Reilly Nicholas G Martin James G Wilson Daniel J Rader Nilesh J Samani Alex P Reiner Robert A Hegele John J P Kastelein Aroon D Hingorani Philippa J Talmud Hakon Hakonarson Clara C Elbers Brendan J Keating Fotios Drenos

Am J Hum Genet 2012 Nov 11;91(5):823-38. Epub 2012 Oct 11.

Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2012.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487124PMC
November 2012

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:
Daniel I Swerdlow Michael V Holmes Karoline B Kuchenbaecker Jorgen E L Engmann Tina Shah Reecha Sofat Yiran Guo Christina Chung Anne Peasey Roman Pfister Simon P Mooijaart Helen A Ireland Maarten Leusink Claudia Langenberg Ka Wah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos John Hardy Michael A Nalls Yun Rose Li Gordon Lowe Marlene Stewart Suzette J Bielinski Julian Peto Nicholas J Timpson John Gallacher Malcolm Dunlop Richard Houlston Ian Tomlinson Ioanna Tzoulaki Jian'an Luan Jolanda M A Boer Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Luigi Ferrucci Stefania Bandenelli Toshiko Tanaka James F Meschia Andrew Singleton Gerjan Navis Irene Mateo Leach Stephan J L Bakker Ron T Gansevoort Ian Ford Stephen E Epstein Mary Susan Burnett Joe M Devaney J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Yolanda van der Graaf Pim A de Jong Anke-Hilse Mailand-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Jeffrey W Stephens Charles B Eaton Jennifer G Robinson JoAnn E Manson F Gerry Fowkes Timonthy M Frayling Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Susan Redline Leslie A Lange Meena Kumari Nick J Wareham W M Monique Verschuren Emelia J Benjamin John C Whittaker Anders Hamsten Frank Dudbridge J A Chris Delaney Andrew Wong Diana Kuh Rebecca Hardy Berta Almoguera Castillo John J Connolly Pim van der Harst Eric J Brunner Michael G Marmot Christina L Wassel Steve E Humphries Philippa J Talmud Mika Kivimaki Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Hakon Hakonarson Alex P Reiner Brendan J Keating Naveed Sattar Aroon D Hingorani Juan Pablo Casas

Lancet 2012 Mar 14;379(9822):1214-24. Epub 2012 Mar 14.

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http://dx.doi.org/10.1016/S0140-6736(12)60110-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316968PMC
March 2012

Blood pressure loci identified with a gene-centric array.

Authors:
Toby Johnson Tom R Gaunt Stephen J Newhouse Sandosh Padmanabhan Maciej Tomaszewski Meena Kumari Richard W Morris Ioanna Tzoulaki Eoin T O'Brien Neil R Poulter Peter Sever Denis C Shields Simon Thom Sasiwarang G Wannamethee Peter H Whincup Morris J Brown John M Connell Richard J Dobson Philip J Howard Charles A Mein Abiodun Onipinla Sue Shaw-Hawkins Yun Zhang George Davey Smith Ian N M Day Debbie A Lawlor Alison H Goodall F Gerald Fowkes Gonçalo R Abecasis Paul Elliott Vesela Gateva Peter S Braund Paul R Burton Christopher P Nelson Martin D Tobin Pim van der Harst Nicola Glorioso Hani Neuvrith Erika Salvi Jan A Staessen Andrea Stucchi Nabila Devos Xavier Jeunemaitre Pierre-François Plouin Jean Tichet Peeter Juhanson Elin Org Margus Putku Siim Sõber Gudrun Veldre Margus Viigimaa Anna Levinsson Annika Rosengren Dag S Thelle Claire E Hastie Thomas Hedner Wai K Lee Olle Melander Björn Wahlstrand Rebecca Hardy Andrew Wong Jackie A Cooper Jutta Palmen Li Chen Alexandre F R Stewart George A Wells Harm-Jan Westra Marcel G M Wolfs Robert Clarke Maria Grazia Franzosi Anuj Goel Anders Hamsten Mark Lathrop John F Peden Udo Seedorf Hugh Watkins Willem H Ouwehand Jennifer Sambrook Jonathan Stephens Juan-Pablo Casas Fotios Drenos Michael V Holmes Mika Kivimaki Sonia Shah Tina Shah Philippa J Talmud John Whittaker Chris Wallace Christian Delles Maris Laan Diana Kuh Steve E Humphries Fredrik Nyberg Daniele Cusi Robert Roberts Christopher Newton-Cheh Lude Franke Alice V Stanton Anna F Dominiczak Martin Farrall Aroon D Hingorani Nilesh J Samani Mark J Caulfield Patricia B Munroe

Am J Hum Genet 2011 Dec 17;89(6):688-700. Epub 2011 Nov 17.

Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234370PMC
December 2011

Bayesian semiparametric meta-analysis for genetic association studies.

Genet Epidemiol 2011 Jul 11;35(5):333-40. Epub 2011 Mar 11.

Department of Epidemiology and Biostatistics, Imperial College, London, United Kingdom.

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http://dx.doi.org/10.1002/gepi.20581DOI Listing
July 2011

Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability.

Genet Epidemiol 2011 Jul 4;35(5):341-9. Epub 2011 Apr 4.

Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/gepi.20582DOI Listing
July 2011

Comparison of methods and sampling designs to test for association between rare variants and quantitative traits.

Genet Epidemiol 2011 May;35(4):226-35

GlaxoSmithKline, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1002/gepi.20570DOI Listing
May 2011

High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort.

J Nutr 2011 May 23;141(5):843-8. Epub 2011 Mar 23.

Centre for Paediatric Epidemiology and Biostatistics and Medical Research Council Centre for the Epidemiology of Child Health, University College London Institute of Child Health, WC1N 1EH, London, UK.

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https://academic.oup.com/jn/article/141/5/843/4600302
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http://dx.doi.org/10.3945/jn.110.133009DOI Listing
May 2011

Maternal and fetal characteristics associated with meconium-stained amniotic fluid.

Obstet Gynecol 2011 Apr;117(4):828-35

Department of Obstetrics and Gynaecology, The Royal London Hospital, Barts and The London NHS Trust, London, United Kingdom.

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http://dx.doi.org/10.1097/AOG.0b013e3182117a26DOI Listing
April 2011

HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer.

J Clin Oncol 2011 Feb 18;29(6):667-73. Epub 2011 Jan 18.

GlaxoSmithKline Research and Development, Genetics Division, Medicines Development Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NF, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2010.31.3197DOI Listing
February 2011

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.

Atherosclerosis 2010 Nov 29;213(1):184-90. Epub 2010 Jul 29.

Centre for Clinical Pharmacology, Division of Medicine, University College London, Rayne Building, 5 University Street, London WC1E 6JF, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.07.021DOI Listing
November 2010

An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism.

Invest Ophthalmol Vis Sci 2010 May 30;51(5):2393-402. Epub 2009 Dec 30.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.09-4228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868481PMC
May 2010

Epigenetic signatures of Silver-Russell syndrome.

J Med Genet 2010 Mar;47(3):150-4

Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.

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http://dx.doi.org/10.1136/jmg.2009.071316DOI Listing
March 2010

Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants.

PLoS One 2010 Feb 9;5(2):e9136. Epub 2010 Feb 9.

Imperial College Cerebrovascular Research Unit, Clinical Neurosciences, Charing Cross Hospital, Imperial College London, London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817726PMC
February 2010

A novel protective prion protein variant that colocalizes with kuru exposure.

N Engl J Med 2009 Nov;361(21):2056-65

Medical Research Council Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, United Kingdom.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa0809716
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November 2009

Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia.

Am J Psychiatry 2009 Sep 1;166(9):1025-30. Epub 2009 Jun 1.

Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin 9, Ireland.

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http://dx.doi.org/10.1176/appi.ajp.2009.08010031DOI Listing
September 2009

Multilocus Bayesian meta-analysis of gene-disease associations.

Am J Hum Genet 2009 May 30;84(5):567-80. Epub 2009 Apr 30.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, WC1E 7HT London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2009.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680997PMC
May 2009

Ischaemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke.

Eur Neurol 2009 28;61(2):76-86. Epub 2008 Nov 28.

Imperial College Cerebrovascular Research Unit, Department of Clinical Neuroscience, Imperial College London & Hammersmith Hospitals, London, UK.

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https://www.karger.com/Article/FullText/177939
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April 2009

The clonal evolution of metastases from primary serous epithelial ovarian cancers.

Int J Cancer 2009 Apr;124(7):1579-86

Gynaecological Cancer Research Laboratories, UCL EGA Institute for Women's Health, University College London, London, UK.

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http://dx.doi.org/10.1002/ijc.24148DOI Listing
April 2009

Review of factors that influence the abundance of ions produced in a tandem mass spectrometer and statistical methods for discovering these factors.

Mass Spectrom Rev 2009 Jan-Feb;28(1):177-87

University of Southampton Clinical Trials Unit, Mailpoint 805, Southampton General Hospital, Southampton Hants SO16 6YD, UK.

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http://dx.doi.org/10.1002/mas.20188DOI Listing
February 2009

The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults.

PLoS One 2008 14;3(11):e3691. Epub 2008 Nov 14.

Imperial College Cerebrovascular Research Unit (ICCRU), Department of Clinical Neuroscience, Imperial College London & Hammersmith Hospitals, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579487PMC
February 2009

Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease.

Am J Hum Genet 2009 Feb 29;84(2):178-87. Epub 2009 Jan 29.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

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http://dx.doi.org/10.1016/j.ajhg.2008.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668013PMC
February 2009

No difference in gender-specific hip replacement outcomes.

Clin Orthop Relat Res 2009 Jan 9;467(1):135-40. Epub 2008 Sep 9.

Division of Orthopaedic Surgery, London Health Sciences Centre, University of Western Ontario, London, ON, Canada.

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http://link.springer.com/10.1007/s11999-008-0466-2
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600988PMC
January 2009

Analysis of multiple SNPs in a candidate gene or region.

Genet Epidemiol 2008 Sep;32(6):560-6

London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1002/gepi.20330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691454PMC
September 2008

Fregene: simulation of realistic sequence-level data in populations and ascertained samples.

BMC Bioinformatics 2008 Sep 8;9:364. Epub 2008 Sep 8.

Department of Epidemiology and Public Health, Imperial College, St Mary's Campus, Norfolk Place, London, W2 1PG, UK.

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http://dx.doi.org/10.1186/1471-2105-9-364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542380PMC
September 2008

Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.

Clin Cancer Res 2008 Sep;14(18):5840-8

Gynaecological Cancer Research Laboratory, University College London Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-0373DOI Listing
September 2008

Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach.

Hum Genet 2008 Jul 24;123(6):633-42. Epub 2008 May 24.

Section of Molecular Genetics and Rheumatology, Faculty of Medicine, Imperial College, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1007/s00439-008-0517-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630773PMC
July 2008

Timing of planned cesarean delivery by racial group.

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Department of Obstetrics and Gynaecology, Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1097/AOG.0b013e318163cd55DOI Listing
March 2008

Genome-wide significance for dense SNP and resequencing data.

Genet Epidemiol 2008 Feb;32(2):179-85

Department of Epidemiology and Public Health, Imperial College London, Norfolk Place, London, UK.

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http://dx.doi.org/10.1002/gepi.20292DOI Listing
February 2008

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.

Nat Genet 2008 Jan 2;40(1):83-9. Epub 2007 Dec 2.

Section of Molecular Genetics and Rheumatology, Imperial College Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1038/ng.2007.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705866PMC
January 2008