John Welch

John Welch

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John Welch

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The secondary structure of a heptapeptide containing trifluoromethyl-λ-tetrafluorosulfanyl substituted amino acids.

Org Biomol Chem 2019 Sep 27;17(35):8079-8082. Epub 2019 Aug 27.

Department of Chemistry, University at Albany, SUNY, 1400 Washington Ave., Albany, NY 12222, USA.

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http://dx.doi.org/10.1039/c9ob01797fDOI Listing
September 2019

TP53 immunohistochemistry correlates with mutation status and clearance in decitabine-treated patients with myeloid malignancies.

Haematologica 2019 Aug 21;104(8):e345-e348. Epub 2019 Feb 21.

Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA

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http://dx.doi.org/10.3324/haematol.2018.205302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669137PMC
August 2019

Invited Commentary.

Authors:
John P Welch

J Am Coll Surg 2019 Jun;228(6):931

Bloomfield, CT.

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http://dx.doi.org/10.1016/j.jamcollsurg.2019.04.012DOI Listing
June 2019

Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity.

Curr Biol 2019 May 9;29(10):1712-1720.e7. Epub 2019 May 9.

Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK; Department of Biochemistry, Charitè, Am Chariteplatz 1, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2019.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538971PMC
May 2019

Serendipity: decitabine monotherapy induced complete molecular response in a 77-year-old patient with acute promyelocytic leukemia.

Haematologica 2019 Apr 7;104(4):e170-e173. Epub 2019 Feb 7.

BMT and Leukemia Program, Department of Medicine, Washington University School of Medicine, Saint Louis, MO

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http://dx.doi.org/10.3324/haematol.2018.209478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442953PMC
April 2019

The distribution of epistasis on simple fitness landscapes.

Biol Lett 2019 Apr;15(4):20180881

2 Department of Genetics, University of Cambridge , Downing Street, Cambridge CB2 3EH , UK.

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http://www.royalsocietypublishing.org/doi/10.1098/rsbl.2018.
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http://dx.doi.org/10.1098/rsbl.2018.0881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501363PMC
April 2019

Smc3 is required for mouse embryonic and adult hematopoiesis.

Exp Hematol 2019 02 13;70:70-84.e6. Epub 2018 Dec 13.

Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2018.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639053PMC
February 2019

Resonance Energy Transfer in a Genetically Engineered Polypeptide Results in Unanticipated Fluorescence Intensity.

Chemistry 2019 Jan 12;25(4):961-965. Epub 2018 Dec 12.

Department of Chemistry, University at Albany, SUNY, 1400 Washington Ave., Albany, NY, 12222, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.2018044
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http://dx.doi.org/10.1002/chem.201804470DOI Listing
January 2019

Immune Escape of Relapsed AML Cells after Allogeneic Transplantation.

N Engl J Med 2018 12 31;379(24):2330-2341. Epub 2018 Oct 31.

From the Division of Oncology, Department of Internal Medicine (M.J.C., A.A.P., M.P.R., C.A.M., E.C., N.M.H., L.D.W., J.S.W., S.E.H., D.C.L., M.J.W., P.W., T.J.L., J.F.D.), the McDonnell Genome Institute (A.A.P., C.A.M., M.O., C.C.F., R.S.F., L.D.W., T.J.L.), the Department of Pathology and Immunology (E.J.D., J.E.P.), and the Division of Biostatistics (J.D.B.), Washington University in St. Louis, St. Louis; the Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN (J.M.K.); the Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH (R.K.W.); and the Center for Cancer Research, Massachusetts General Hospital, Boston (T.A.G.).

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http://www.nejm.org/doi/10.1056/NEJMoa1808777
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http://dx.doi.org/10.1056/NEJMoa1808777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322675PMC
December 2018

Patterns of mutations in TP53 mutated AML.

Authors:
John S Welch

Best Pract Res Clin Haematol 2018 12 20;31(4):379-383. Epub 2018 Sep 20.

Department of Internal Medicine, Washington University, 660 Euclid Ave, Box 8007, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482955PMC
December 2018

Coadapted genomes and selection on hybrids: Fisher's geometric model explains a variety of empirical patterns.

Evol Lett 2018 Oct 14;2(5):472-498. Epub 2018 Aug 14.

Department of Genetics University of Cambridge Downing St. Cambridge CB23EH United Kingdom.

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http://dx.doi.org/10.1002/evl3.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145440PMC
October 2018

In Regard to Beadle and Anderson.

Int J Radiat Oncol Biol Phys 2018 09 8;102(1):229-230. Epub 2018 Aug 8.

Institute of Head and Neck Studies and Education, Department of Head and Neck Surgery, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1016/j.ijrobp.2018.05.015DOI Listing
September 2018

Mutation Clearance after Transplantation for Myelodysplastic Syndrome.

N Engl J Med 2018 Sep;379(11):1028-1041

From the Department of Pathology and Immunology (E.J.D.), the Department of Medicine, Division of Oncology (M.A.J., C.A.M., N.E., J.S., K.E., J.R., S.E.H., K.B., L.D.W., M.J.C., I.P., J.S.W., G.L.U., D.C.L., J.F.D., P.W., T.J.L., M.J.W.), the McDonnell Genome Institute (G.S.C., C.A.M., H.A., R.S.F., C.C.F., M.O.), the Department of Medicine, Division of Hospital Medicine (R.S.), and Siteman Biostatistics Shared Resource, Siteman Cancer Center (K.T.), Washington University School of Medicine in St. Louis, St. Louis; and Massachusetts General Hospital Cancer Center, Boston (T.A.G.).

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http://www.nejm.org/doi/10.1056/NEJMoa1804714
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http://dx.doi.org/10.1056/NEJMoa1804714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309244PMC
September 2018

Screwworm (Diptera: Calliphoridae) in the United States: Response to and Elimination of the 2016-2017 Outbreak in Florida.

J Med Entomol 2018 06;55(4):777-786

USDA-APHIS-IS, Action Programs, USDA, ARS, SPARC, College Station, TX.

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http://dx.doi.org/10.1093/jme/tjy049DOI Listing
June 2018

Molecular Characterization of the 2016 New World Screwworm (Diptera: Calliphoridae) Outbreak in the Florida Keys.

J Med Entomol 2018 06;55(4):938-946

U.S. Department of Agriculture-Agricultural Research Service, Daniel K. Inouye U.S. Pacific Basin Agricultural Research Center, Hilo, HI.

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http://dx.doi.org/10.1093/jme/tjy078DOI Listing
June 2018

The control of stereochemistry by the pentafluorosulfanyl group.

Org Biomol Chem 2018 05;16(17):3151-3159

Department of Chemistry, University at Albany, SUNY, 1400 Washington Ave., Albany, NY 12222, USA.

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http://dx.doi.org/10.1039/c7ob03146gDOI Listing
May 2018

Acute Myeloid Leukemia: The Good, the Bad, and the Ugly.

Am Soc Clin Oncol Educ Book 2018 May;38:555-573

From the Moffitt Cancer Center, Tampa, FL; CHU Lille, INSERM, Laboratory of Hematology, University of Lille, Lille, France; Hematology Department, Saint-Louis Hospital, Paris Diderot University, Paris, France; Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1200/EDBK_199519DOI Listing
May 2018

Why Might Bacterial Pathogens Have Small Genomes?

Trends Ecol Evol 2017 12 17;32(12):936-947. Epub 2017 Oct 17.

Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK.

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http://dx.doi.org/10.1016/j.tree.2017.09.006DOI Listing
December 2017

In Reply to Zoto Mustafayev and Ozyar.

Int J Radiat Oncol Biol Phys 2017 12;99(5):1307

Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.ijrobp.2017.08.036DOI Listing
December 2017

Prophylactic Vitamin D Supplementation in High-Risk Breastfed Infants.

J Paediatr Child Health 2017 12;53(12):1244

Paediatric Endocrinologist Department of Paediatric Endocrinology and Diabetes, Monash Children's Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/jpc.13730DOI Listing
December 2017

Endogenous retinoid X receptor ligands in mouse hematopoietic cells.

Sci Signal 2017 Oct 31;10(503). Epub 2017 Oct 31.

Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/scisignal.aan1011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777239PMC
October 2017

Formation of an international intergroup to coordinate clinical trials in head and neck cancers: HNCIG.

Oral Oncol 2017 08 22;71:180-183. Epub 2017 Jun 22.

Institute of Head & Neck Studies and Education, University of Birmingham, Birmingham, UK. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2017.05.022DOI Listing
August 2017

Clinical Utility of Epstein-Barr Virus DNA Testing in the Treatment of Nasopharyngeal Carcinoma Patients.

Int J Radiat Oncol Biol Phys 2017 08 18;98(5):996-1001. Epub 2017 Mar 18.

Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.ijrobp.2017.03.018DOI Listing
August 2017

It's Been a Hard Day's Night-What Determines Impact of Less Than 24/7 Rapid Response Systems?

Crit Care Med 2017 06;45(6):1104-1105

Departments of Acute Medicine and Intensive Care, Ysbyty Gwynedd & School of Medical Sciences, Bangor University, Bangor, United Kingdom Critical Care & Critical Care Outreach, University College London Hospitals, London, United Kingdom.

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http://dx.doi.org/10.1097/CCM.0000000000002358DOI Listing
June 2017

Invited Commentary.

Authors:
John P Welch

J Am Coll Surg 2017 06;224(6):1083

Bloomfield, CT.

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http://dx.doi.org/10.1016/j.jamcollsurg.2017.03.010DOI Listing
June 2017

Analysis of esophagogastric cancer patients enrolled in the National Cancer Institute Cancer Therapy Evaluation Program sponsored phase 1 trials.

Gastric Cancer 2017 May 10;20(3):481-488. Epub 2016 Aug 10.

Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10120-016-0629-xDOI Listing
May 2017

Studies of the Binding of Modest Modulators of the Human Enzyme, Sirtuin 6, by STD NMR.

Chembiochem 2017 05 18;18(10):931-940. Epub 2017 Apr 18.

Department of Chemistry, University at Albany, 1400 Washington Avenue, Albany, NY, 12205, USA.

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http://dx.doi.org/10.1002/cbic.201600655DOI Listing
May 2017

Capacity building for critical care training delivery: Development and evaluation of the Network for Improving Critical care Skills Training (NICST) programme in Sri Lanka.

Intensive Crit Care Nurs 2017 Apr 24;39:28-36. Epub 2016 Nov 24.

National Intensive Care Surveillance, Ministry of Health, Colombo, Sri Lanka; Faculty of Medicine, University of Colombo, Colombo, Sri Lanka; Mahidol Oxford Tropical Medicine Research Unit (MORU), Bangkok, Thailand. Electronic address:

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http://dx.doi.org/10.1016/j.iccn.2016.08.008DOI Listing
April 2017

Effectiveness of ways to improve detection and rescue of deteriorating patients.

Br J Hosp Med (Lond) 2017 Mar;78(3):150-159

Professor of Health Services Research, Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London.

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http://dx.doi.org/10.12968/hmed.2017.78.3.150DOI Listing
March 2017

Impact of implementation of the National Early Warning Score on patients and staff.

Br J Hosp Med (Lond) 2017 Mar;78(3):132-136

Consultant Nurse, Critical Care & Critical Care Outreach, University College London Hospitals NHS Foundation Trust, London NW1 2BU.

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http://dx.doi.org/10.12968/hmed.2017.78.3.132DOI Listing
March 2017

CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.

Cell 2017 02 16;168(5):801-816.e13. Epub 2017 Feb 16.

Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; The McDonnell Genome Institute, Washington University, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328582PMC
February 2017

Decitabine in TP53-Mutated AML.

N Engl J Med 2017 02;376(8):797-8

Washington University School of Medicine, St. Louis, MO

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http://dx.doi.org/10.1056/NEJMc1616062DOI Listing
February 2017

What's wrong with evolutionary biology?

Authors:
John J Welch

Biol Philos 2017 20;32(2):263-279. Epub 2016 Dec 20.

Department of Genetics, University of Cambridge, Cambridge, CB23EH UK.

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http://dx.doi.org/10.1007/s10539-016-9557-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329086PMC
December 2016

TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

N Engl J Med 2016 11;375(21):2023-2036

the Department of Internal Medicine, Division of Oncology (J.S.W., L.D.W., G.L.U., A.G., M.H.T., I.P., R.R., T.A.F., K.E.S.-G., R.V., S.T.O., C.N.A., A.F.C., M.A.S., M.A.J., S.E.H., K.L., M.R.J., M.J.W., P.W., D.C.L., J.F.D., T.J.L.), and the Division of Biostatistics (J.D.B.), and the Department of Pathology and Immunology (E.J.D., B.T., Y.-S.L.), Washington University School of Medicine, and McDonnell Genome Institute, Washington University in St. Louis (A.A.P., C.A.M., C.C.F., M.O., R.S.F., R.K.W., L.D.W., T.J.L.) - both in St. Louis; the Departments of Internal Medicine (A.H., N.K., M.J.S., W.S.) and Pharmacy (R.W.K.), University of Chicago, Chicago; and the Department of Internal Medicine (T.A.G.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1056/NEJMoa1605949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217532PMC
November 2016

Clinical outcomes of patients seen by Rapid Response Teams: A template for benchmarking international teams.

Resuscitation 2016 10 11;107:7-12. Epub 2016 Jul 11.

Department of Intensive Care, Austin Hospital, 145 Studley Rd, Heidelberg, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2016.07.001DOI Listing
October 2016

The genetics of speciation: Insights from Fisher's geometric model.

Evolution 2016 07 5;70(7):1450-64. Epub 2016 Jul 5.

Department of Genetics, University of Cambridge, Downing Street, Cambridge, United Kingdom.

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http://dx.doi.org/10.1111/evo.12968DOI Listing
July 2016

Pathways of retinoid synthesis in mouse macrophages and bone marrow cells.

J Leukoc Biol 2016 06 14;99(6):797-810. Epub 2016 Jan 14.

Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA and

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http://doi.wiley.com/10.1189/jlb.2HI0415-146RR
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http://dx.doi.org/10.1189/jlb.2HI0415-146RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952016PMC
June 2016

Rapid response teams improve outcomes: yes.

Intensive Care Med 2016 Apr 5;42(4):593-595. Epub 2016 Feb 5.

Critical Care and Critical Care Outreach, University College London Hospitals, University College London Partners Patient Safety Collaborative, London, UK.

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http://dx.doi.org/10.1007/s00134-016-4219-5DOI Listing
April 2016

A sustainable approach to training nurses in acute care skills in a resource limited setting (Network for Intensive Care Skills Training, NICST).

Resuscitation 2016 Apr 11;101:e1-2. Epub 2016 Feb 11.

National Intensive Care Surveillance, Ministry of Health, Colombo, Sri Lanka; Mahidol Oxford Tropical Medicine Research Unit (MORU), Bangkok, Thailand; Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. Electronic address:

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http://dx.doi.org/10.1016/j.resuscitation.2016.01.017DOI Listing
April 2016

The Phylogeny of Rickettsia Using Different Evolutionary Signatures: How Tree-Like is Bacterial Evolution?

Syst Biol 2016 Mar 11;65(2):265-79. Epub 2015 Nov 11.

Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK; and.

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http://dx.doi.org/10.1093/sysbio/syv084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748751PMC
March 2016

Hand-foot syndrome following decitabine.

Ann Hematol 2016 Feb 6;95(3):535-6. Epub 2015 Nov 6.

Division of Oncology, Stem Cell Biology Section, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8007, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s00277-015-2546-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175272PMC
February 2016

Local interspecies introgression is the main cause of extreme levels of intraspecific differentiation in mussels.

Mol Ecol 2016 01 30;25(1):269-86. Epub 2015 Jul 30.

Institut des Sciences de l'Evolution (UMR 5554), CNRS - Université Montpellier, Place Eugène Bataillon, 34095, Montpellier, France.

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http://dx.doi.org/10.1111/mec.13299DOI Listing
January 2016

The effect of genetic structure on molecular dating and tests for temporal signal.

Methods Ecol Evol 2016 Jan 22;7(1):80-89. Epub 2015 Sep 22.

Department of Genetics University of Cambridge Downing Street Cambridge CB2 3EH UK.

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http://dx.doi.org/10.1111/2041-210X.12466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832290PMC
January 2016

National Cancer Institute's Precision Medicine Initiatives for the new National Clinical Trials Network.

Am Soc Clin Oncol Educ Book 2014 :71-6

From the Division of Cancer Treatment and Diagnosis, National Cancer Institute at the National Institutes of Health, Bethesda, MD; Center for Cancer Genomics, National Cancer Institute at the National Institutes of Health, Bethesda, MD; and Leidos Corporation, Frederick, MD.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.71DOI Listing
November 2015

Reply to Letter: 'Re: Education for cardiac arrest - Treatment or prevention?'.

Resuscitation 2015 Nov 20;96:e13-4. Epub 2015 Jun 20.

University of Melbourne, Melbourne, VIC 3010, Australia; Monash University, Melbourne, VIC 3004, Australia; Austin Hospital, Melbourne, VIC 3084, Australia.

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http://dx.doi.org/10.1016/j.resuscitation.2015.06.009DOI Listing
November 2015

Reply to Letter: 'Re: Education for cardiac arrest - Prevention and treatment'.

Resuscitation 2015 Nov 20;96:e9-e10. Epub 2015 Jun 20.

University of Melbourne, Melbourne, VIC 3010, Australia; Monash University, Melbourne, VIC 3004, Australia; Austin Hospital, Melbourne, VIC 3084, Australia.

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http://dx.doi.org/10.1016/j.resuscitation.2015.06.010DOI Listing
November 2015

The evolution, diversity, and host associations of rhabdoviruses.

Virus Evol 2015 13;1(1):vev014. Epub 2015 Nov 13.

Department of Genetics, University of Cambridge, Cambridge, CB2 3EH.

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http://dx.doi.org/10.1093/ve/vev014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014481PMC
November 2015

The National Clinical Trials Network: Conducting Successful Clinical Trials of New Therapies for Rare Cancers.

Semin Oncol 2015 Oct 10;42(5):731-9. Epub 2015 Jul 10.

Division of Hematology and Oncology, Center for Personalized Therapy and Clinical Trials Office UC San Diego-Moores Cancer Center, San Diego, CA.

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http://dx.doi.org/10.1053/j.seminoncol.2015.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673983PMC
October 2015

Education for cardiac arrest--Treatment or prevention?

Resuscitation 2015 Jul 25;92:59-62. Epub 2015 Apr 25.

University of Melbourne, Melbourne, VIC 3010, Australia; Monash University, Melbourne, VIC 3004, Australia; Intensive Care Specialist, Austin Hospital, Melbourne, VIC 3084, Australia.

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http://dx.doi.org/10.1016/j.resuscitation.2015.04.018DOI Listing
July 2015

Wolbachia in butterflies and moths: geographic structure in infection frequency.

Front Zool 2015 16;12:16. Epub 2015 Jul 16.

Institute of Food and Agricultural Sciences, Tropical Research and Education Center, University of Florida, 18905 SW 280th Street, 33031 Homestead, FL USA.

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http://dx.doi.org/10.1186/s12983-015-0107-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502936PMC
July 2015

The role of proline-containing peptide triads in β-sheet formation: A kinetic study.

Biopolymers 2015 Jun;103(6):339-50

Department of Chemistry, University at Albany, State University of New York, Albany, NY, 12222.

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http://dx.doi.org/10.1002/bip.22622DOI Listing
June 2015

The incidence of bacterial endosymbionts in terrestrial arthropods.

Proc Biol Sci 2015 May;282(1807):20150249

Department of Genetics, University of Cambridge, Downing Street, Cambridge, UK

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http://dx.doi.org/10.1098/rspb.2015.0249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424649PMC
May 2015

Nursing intensive care skills training: a nurse led, short, structured, and practical training program, developed and tested in a resource-limited setting.

J Crit Care 2015 Apr 30;30(2):438.e7-11. Epub 2014 Oct 30.

National Intensive Care Surveillance, Quality Secretariat Building, Castle Street Hospital for Women, Colombo, Sri Lanka; Mahidol Oxford Tropical Medicine Research Unit (MORU), Bangkok, Thailand; Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2014.10.024DOI Listing
April 2015

Rates of vaccine evolution show strong effects of latency: implications for varicella zoster virus epidemiology.

Mol Biol Evol 2015 Apr 6;32(4):1020-8. Epub 2015 Jan 6.

Division of Infection and Immunity, MRC Centre for Medical Molecular Virology, UCL, London, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msu406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379407PMC
April 2015

Preparation and utility of organic pentafluorosulfanyl-containing compounds.

Chem Rev 2015 Jan 24;115(2):1130-90. Epub 2014 Oct 24.

Department of Chemistry, University at Albany, State University of New York , 1400 Washington Avenue, Albany, New York 12222, United States.

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http://dx.doi.org/10.1021/cr500336uDOI Listing
January 2015

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nat Med 2014 Dec 19;20(12):1472-8. Epub 2014 Oct 19.

1] The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, USA. [2] Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA. [3] Department of Genetics, Washington University in St. Louis, St. Louis, Missouri, USA. [4] Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nm.3733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313872PMC
December 2014

Possible footprints of APOBEC3F and/or other APOBEC3 deaminases, but not APOBEC3G, on HIV-1 from patients with acute/early and chronic infections.

J Virol 2014 Nov 27;88(21):12882-94. Epub 2014 Aug 27.

MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, United Kingdom Nuffield Department of Clinical Neurosciences, Division of Clinical Neurology, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, United Kingdom

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http://dx.doi.org/10.1128/JVI.01460-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248940PMC
November 2014

The evolution and genetics of virus host shifts.

PLoS Pathog 2014 Nov 6;10(11):e1004395. Epub 2014 Nov 6.

Department of Genetics, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1004395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223060PMC
November 2014

Mutation position within evolutionary subclonal architecture in AML.

Authors:
John S Welch

Semin Hematol 2014 Oct 7;51(4):273-81. Epub 2014 Aug 7.

Washington University School of Medicine, Division of Oncology, Stem Cell Biology Section, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2014.08.004DOI Listing
October 2014

Consensus report of a joint NCI thoracic malignancies steering committee: FDA workshop on strategies for integrating biomarkers into clinical development of new therapies for lung cancer leading to the inception of "master protocols" in lung cancer.

J Thorac Oncol 2014 Oct;9(10):1443-8

*Clinical Investigations Branch, Cancer Therapy Evaluation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD; †Offices of Hematology and Oncology Products, Center for Drug Evaluation and Research U.S. Food and Drug Administration, Silver Spring, MD; ‡University of Pittsburgh Medical Center, Pittsburgh, PA; §University of Utah, Salt Lake City, UT; ‖Duke University Medical Center, Durham, NC; ¶Biometric Research Branch, Cancer Therapy Evaluation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD; and #University of Colorado, School of Medicine, Denver, CO.

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http://dx.doi.org/10.1097/JTO.0000000000000314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165474PMC
October 2014

Chimera-induced folding: implications for amyloidosis.

Biomacromolecules 2014 Aug 15;15(8):2992-3001. Epub 2014 Jul 15.

Department of Chemistry and §Department of Biological Sciences, University at Albany, State University of New York , Albany, New York 12222, United States.

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http://dx.doi.org/10.1021/bm5006068DOI Listing
August 2014

Standing and flowing: the complex origins of adaptive variation.

Mol Ecol 2014 Aug;23(16):3935-7

Department of Genetics, University of Cambridge, Downing St., Cambridge, CB23EH, UK.

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http://dx.doi.org/10.1111/mec.12859DOI Listing
August 2014

SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

PLoS Comput Biol 2014 Aug 7;10(8):e1003665. Epub 2014 Aug 7.

The Genome Institute, Washington University, St. Louis, Missouri, United States of America; Department of Internal Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Genetics, Washington University, St. Louis, Missouri, United States of America; Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125065PMC
August 2014

Gene-flow in a mosaic hybrid zone: is local introgression adaptive?

Genetics 2014 Jul 29;197(3):939-51. Epub 2014 Apr 29.

Université Montpellier 2, 34095 Montpellier Cedex 5, France CNRS, Institut des Sciences de l'Evolution, ISEM Unité Mixte de Recherche 5554, 34200 SETE, France.

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http://dx.doi.org/10.1534/genetics.114.161380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096372PMC
July 2014

Inferring host range dynamics from comparative data: the protozoan parasites of new world monkeys.

Am Nat 2014 Jul 3;184(1):65-74. Epub 2014 Jun 3.

Centre for Computational Systems Biology, Fudan University, Shanghai 200433, People's Republic of China.

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http://dx.doi.org/10.1086/676589DOI Listing
July 2014

Invited commentary.

Authors:
John P Welch

J Am Coll Surg 2014 Jun;218(6):1161-2

Bloomfield, CT.

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http://dx.doi.org/10.1016/j.jamcollsurg.2014.03.011DOI Listing
June 2014