Publications by authors named "John W Park"

100Publications

Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial.

JAMA Oncol 2020 Sep;6(9):1355-1362

Berry Consultants, LLC, Austin, Texas.

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September 2020

Phase II study of irinotecan and temozolomide in breast cancer patients with progressing central nervous system disease.

Breast Cancer Res Treat 2019 Sep 6;177(2):401-408. Epub 2019 Jun 6.

Department of Medicine, Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA, USA.

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September 2019

Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.

JCO Precis Oncol 2018 16;2. Epub 2018 Aug 16.

, , and , George Mason University, Manassas, VA; , , , , , , , and , University of California, San Francisco, San Francisco, CA; , , and , Netherlands Cancer Institute, Amsterdam, the Netherlands; , University of Pennsylvania, Philadelphia, PA; , University of Texas MD Anderson Cancer Center, Houston; , Berry Consultants, Austin, TX; , University of Minnesota, Minneapolis; and , Mayo Clinic, Rochester, MN.

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August 2018

Discovery of internalizing antibodies to basal breast cancer cells.

Protein Eng Des Sel 2018 01;31(1):17-28

Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, Zuckerberg San Francisco General Hospital and Trauma Center, 1001 Potrero Ave, San Francisco, CA 94110, USA.

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January 2018

Pure CTCs, advanced WGS, and precise personalized combination therapies.

Oncoscience 2017 Jul 21;4(7-8):75-76. Epub 2017 Sep 21.

Complete Genomics, Inc., San Jose, California; BGI-Shenzhen, Shenzhen, China.

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July 2017

Enumeration of Circulating Tumor Cells and Disseminated Tumor Cells in Blood and Bone Marrow by Immunomagnetic Enrichment and Flow Cytometry (IE/FC).

Methods Mol Biol 2017 ;1634:203-210

Division of Hematology Oncology, Helen Diller Family Comprehensive Cancer Center, University of California-San Francisco, Box 1387, 2340 Sutter St., S471, San Francisco, CA, 94115, USA.

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April 2018

Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration.

Adv Exp Med Biol 2017 ;994:119-131

Division of Hematology & Oncology, University of California San Francisco, San Francisco, CA, 94115, USA.

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October 2017

A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma.

Cancer Chemother Pharmacol 2017 03 23;79(3):603-610. Epub 2017 Feb 23.

Division of Neuro-oncology, Department of Neurological Surgery, University of California, San Francisco (UCSF), 505 Parnassus Avenue M779, San Francisco, CA, 94143, USA.

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March 2017

Circulating tumor cells in breast cancer: applications in personalized medicine.

Breast Cancer Res Treat 2016 12 19;160(3):411-424. Epub 2016 Oct 19.

Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1600 Divisadero Street, San Francisco, CA, 94115, USA.

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December 2016

Adaptive Randomization of Neratinib in Early Breast Cancer.

N Engl J Med 2016 Jul;375(1):11-22

From University of California, San Francisco (J.W.P., C.Y., L.J.V., N.M.H., M.B.B., A.J.C., M.M., J.L., S.E.D., G.L.H., L.J.E.), and QuantumLeap Healthcare Collaborative (M.P.), San Francisco, Buck Institute for Research and Aging, Novato (C.Y.), University of California, Davis, Davis (M.H.), University of California, San Diego, San Diego (A.M.W., R.S., T.H.), and University of Southern California, Los Angeles (D.T.) - all in California; Georgetown Lombardi Comprehensive Cancer Center, Washington, DC (M.C.L., C.I.); University of Minnesota, Minneapolis (D.Y., T.C.H.), and Mayo Clinic, Rochester (J.C.B.) - both in Minnesota; M.D. Anderson Cancer Center, Houston (W.F.S., L.P., S.L.M., D.A.B.), University of Texas Southwestern Medical Center, Dallas (D.M.E., B.B.H.), and Berry Consultants, Austin (A.S., D.A.B.) - all in Texas; Gemini Group, Ann Arbor, MI (J.P.); University of Pennsylvania, Philadelphia (A.D.); Oregon Health and Sciences University, Portland (S.Y.C., K.A.K.); Swedish Medical Center, Seattle (H.G.K.); University of Chicago (R.N.) and Loyola University (K.S.A.) - both in Chicago; Inova Fairfax Hospital, Falls Church, VA (K.K.E.); University of Denver, Denver (A.D.E.); Mayo Clinic, Scottsdale (D.W.N.), and University of Arizona, Tucson (J.E.L., R.K.V.) - both in Arizona; University of Kansas, Lawrence (Q.J.K.); and Emory University, Atlanta (W.C.W.).

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July 2016

Detection of cerebrospinal fluid tumor cells and its clinical relevance in leptomeningeal metastasis of breast cancer.

Breast Cancer Res Treat 2015 Nov 31;154(2):339-49. Epub 2015 Oct 31.

Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 2340 Sutter Street, San Francisco, CA, 94115, USA.

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November 2015

Genome-wide copy number analysis of cerebrospinal fluid tumor cells and their corresponding archival primary tumors.

Genom Data 2014 Dec 18;2:60-2. Epub 2014 Apr 18.

Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA, USA ; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.

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December 2014

Approaches to isolation and molecular characterization of disseminated tumor cells.

Oncotarget 2015 Oct;6(31):30715-29

Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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October 2015

Circulating tumor cell analysis in metastatic triple-negative breast cancers.

Clin Cancer Res 2015 Mar 18;21(5):1098-105. Epub 2014 Dec 18.

University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California.

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March 2015

Expression profiling of circulating tumor cells in metastatic breast cancer.

Breast Cancer Res Treat 2015 Jan 29;149(1):121-31. Epub 2014 Nov 29.

Division of Breast and Soft Tissue Surgery, Department of Surgery, Norris Comprehensive Cancer Center (NCCC), University of Southern California (USC), 1510 San Pablo Street Suite 412, Los Angeles, CA, 90033-0800, USA,

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January 2015

The cancer glycocalyx mechanically primes integrin-mediated growth and survival.

Nature 2014 Jul 25;511(7509):319-25. Epub 2014 Jun 25.

1] Department of Surgery and Center for Bioengineering and Tissue Regeneration, University of California, San Francisco, California 94143, USA [2] Bay Area Physical Sciences-Oncology Program, University of California, Berkeley, California 94720, USA [3] Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA [4] Departments of Anatomy and Bioengineering and Therapeutic Sciences and Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California 94143, USA.

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July 2014

Advances in genomic characterization of circulating tumor cells.

Cancer Metastasis Rev 2014 Sep;33(2-3):757-69

Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 2340 Sutter St, San Francisco, CA, 94115, USA,

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September 2014

Phase I dose-escalation study of 5-day intermittent oral lapatinib therapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer.

J Clin Oncol 2014 May 7;32(14):1472-9. Epub 2014 Apr 7.

A. Jo Chien, Pamela N. Munster, Michelle E. Melisko, Hope S. Rugo, John W. Park, Andrei Goga, Glenna Auerback, Elham Khanafshar, and Mark M. Moasser, Helen Diller Family Comprehensive Cancer Center; A. Jo Chien, Pamela N. Munster, Michelle E. Melisko, Hope S. Rugo, John W. Park, Andrei Goga, Glenna Auerback, Elham Khanafshar, Karen Ordovas, and Mark M. Moasser, University of California San Francisco, San Francisco, CA; and Kevin M. Koch, GlaxoSmithKline, Research Triangle Park, NC.

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May 2014

Molecular profiling of tumor cells in cerebrospinal fluid and matched primary tumors from metastatic breast cancer patients with leptomeningeal carcinomatosis.

Cancer Res 2013 Dec 18;73(23):7134-43. Epub 2013 Oct 18.

Authors' Affiliations: Division of Hematology/Oncology; Helen Diller Family Comprehensive Cancer Center; and Helen Diller Family Comprehensive Cancer Center Computational Biology Core, University of California San Francisco, San Francisco, California.

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December 2013

Isolation of circulating tumor cells by immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS) for molecular profiling.

Methods 2013 Dec 26;64(2):114-8. Epub 2013 Jul 26.

Division of Hematology/Oncology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, United States.

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December 2013

Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients.

Cancer Res 2013 Jan 7;73(1):30-40. Epub 2012 Nov 7.

Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA 94115, USA.

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January 2013

Nanovector-based therapies in advanced pancreatic cancer.

J Gastrointest Oncol 2011 Sep;2(3):185-94

National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan;

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September 2011

Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer.

BMC Cancer 2012 Feb 28;12:78. Epub 2012 Feb 28.

Department of Medicine, Division of Hematology/Oncology, University of California San Francisco, USA.

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February 2012

Experimental radionuclide therapy of HER2-expressing xenografts using two-step targeting nuclisome particles.

J Nucl Med 2012 Mar 8;53(3):480-7. Epub 2012 Feb 8.

Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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March 2012

A phase II study of lapatinib and bevacizumab as treatment for HER2-overexpressing metastatic breast cancer.

Breast Cancer Res Treat 2012 Jul 24;134(1):13-20. Epub 2011 Dec 24.

Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, 1600 Divisadero St., 2nd Floor, Box 1710, B-608, San Francisco, CA 94143, USA.

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July 2012

Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts.

Neuro Oncol 2011 Dec 27;13(12):1288-95. Epub 2011 Sep 27.

Department of Neurological Surgery, University of California-San Francisco, 1450 Third St, San Francisco, CA 94158, USA.

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December 2011

Disseminated tumor cells: the method is the message.

Authors:
John W Park

Breast Cancer Res Treat 2011 Feb 11;125(3):739-40. Epub 2010 Aug 11.

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94115, USA.

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February 2011

Canine spontaneous glioma: a translational model system for convection-enhanced delivery.

Neuro Oncol 2010 Sep 20;12(9):928-40. Epub 2010 May 20.

Department of Surgical and Radiological of Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California 95616-8745, USA.

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September 2010

Characterization of a novel, trastuzumab resistant human breast cancer cell line.

Front Biosci (Elite Ed) 2010 Jan 1;2:627-40. Epub 2010 Jan 1.

Department of Biophysics and Cell Biology, Faculty of Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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January 2010

A comparison of RNA amplification techniques at sub-nanogram input concentration.

BMC Genomics 2009 Jul 20;10:326. Epub 2009 Jul 20.

Department of Surgery, UCSF Comprehensive Cancer Center, 1500 Divisadero Street, San Francisco, CA 94143, USA.

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July 2009

Unraveling the biologic and clinical complexities of HER2.

Clin Breast Cancer 2008 Oct;8(5):392-401

Comprehensive Cancer Center, University of California, San Francisco, CA 94115-1710, USA.

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October 2008

Improved pharmacokinetics and efficacy of a highly stable nanoliposomal vinorelbine.

J Pharmacol Exp Ther 2009 Jan 23;328(1):321-30. Epub 2008 Oct 23.

Hermes Biosciences, Inc., 61 Airport Blvd., Suite D, South San Francisco, CA 94080, USA.

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January 2009

Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development.

J Pharm Sci 2008 Nov;97(11):4696-740

Hermes Biosciences, Inc., South San Francisco, California 94080, USA.

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November 2008

A role for biomarkers in the screening and diagnosis of breast cancer in younger women.

Expert Rev Mol Diagn 2007 Sep;7(5):533-44

University of California, San Francisco, Department of Surgery, 1600 Divisadero Street, Box 1710, San Francisco, CA 94115, USA.

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September 2007

Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer.

Mol Pharmacol 2007 Jun 28;71(6):1525-34. Epub 2007 Mar 28.

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945, USA.

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June 2007

Real-time imaging and quantification of brain delivery of liposomes.

Pharm Res 2006 Nov 14;23(11):2493-504. Epub 2006 Sep 14.

Department of Neurological Surgery, Laboratory for Molecular Therapeutics, University of California San Francisco, San Francisco, California, USA.

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November 2006

Validated high-throughput screening of drug-like small molecules for inhibitors of ErbB2 transcription.

Assay Drug Dev Technol 2006 Jun;4(3):273-84

Program of Cancer and Development Therapeutics, Buck Institute for Age Research, Novato, CA 94945, USA.

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June 2006

EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells.

J Drug Target 2006 May;14(4):215-23

Division of Oncology, Department of Internal Medicine, University Hospital of Basel, Petersgraben 4, CH-4031 Basel, Switzerland.

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May 2006

Convection-enhanced delivery of Ls-TPT enables an effective, continuous, low-dose chemotherapy against malignant glioma xenograft model.

Neuro Oncol 2006 Jul 24;8(3):205-14. Epub 2006 May 24.

Department of Neurological Surgery, University of California at San Francisco, 1855 Folsom Street, Mission Center Building Room 226, San Francisco, CA 94103, USA.

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July 2006

The "perivascular pump" driven by arterial pulsation is a powerful mechanism for the distribution of therapeutic molecules within the brain.

Mol Ther 2006 Jul 2;14(1):69-78. Epub 2006 May 2.

Laboratory of Molecular Therapeutics, Department of Neurological Surgery, UCSF, MCB, 1855 Folsom Street, Room 226, San Francisco, CA 94103, USA.

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July 2006

Tissue affinity of the infusate affects the distribution volume during convection-enhanced delivery into rodent brains: implications for local drug delivery.

J Neurosci Methods 2006 Jun 10;154(1-2):225-32. Epub 2006 Feb 10.

Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, Mission Center Building, 94103, USA.

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June 2006

Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents.

J Neurosurg 2005 Nov;103(5):923-9

Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, California 94103, USA.

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November 2005

Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain.

Exp Neurol 2005 Dec 28;196(2):381-9. Epub 2005 Sep 28.

Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, 1855 Folsom Street, Room 226, San Francisco, CA 94103, USA.

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December 2005

Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging.

Brain Res Brain Res Protoc 2005 Dec 21;16(1-3):20-6. Epub 2005 Sep 21.

Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, 1855 Folsom Street, Room 226, San Francisco, CA 94103, USA.

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December 2005

Associations of ErbB2, beta1-integrin and lipid rafts on Herceptin (Trastuzumab) resistant and sensitive tumor cell lines.

Cancer Lett 2005 Sep;227(2):201-12

Department of Biophysics and Cell Biology, Research Center for Molecular Medicine, Faculty of Medicine, Medical and Health Science Center, University of Debrecen, P.O. Box 39, Nagyerdei krt. 98, H-4012 Debrecen, Hungary.

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September 2005

Brain metastases of breast cancer.

Expert Rev Anticancer Ther 2005 Apr;5(2):253-68

Division of Hematology-Oncology, University of California at San Francisco, San Francisco, CA 94115, USA.

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April 2005

Immune dysfunction and micrometastases in women with breast cancer.

Breast Cancer Res Treat 2005 May;91(2):163-71

Department of Surgery, University of California, San Francisco, CA 94115, USA.

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May 2005

Selecting the right fluorophores and flow cytometer for fluorescence resonance energy transfer measurements.

Cytometry A 2005 Jun;65(2):148-57

Department of Biophysics and Cell Biology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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June 2005

Future directions of liposome- and immunoliposome-based cancer therapeutics.

Semin Oncol 2004 Dec;31(6 Suppl 13):196-205

UCSF Comprehensive Cancer Center, San Francisco, CA 94115-1710, USA.

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December 2004

Time to disease progression to evaluate a novel protein kinase C inhibitor, UCN-01, in renal cell carcinoma.

Cancer 2004 Jul;101(1):90-5

UCSF Comprehensive Cancer Center, The University of California-San Francisco, 1600 Divisadero, Rm. A717, San Francisco, CA 94115, USA.

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July 2004

Liposome-based approaches to overcome anticancer drug resistance.

Drug Resist Updat 2003 Oct;6(5):271-9

Division of Hematology/Oncology, University of California, San Francisco (UCSF), 2340 Sutter Street, San Francisco, CA 94115, USA.

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October 2003