John V Reynolds

John V Reynolds

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John V Reynolds

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Identifying a Novel Role for Fractalkine (CX3CL1) in Memory CD8 T Cell Accumulation in the Omentum of Obesity-Associated Cancer Patients.

Authors:
Melissa J Conroy Stephen G Maher Ashanty M Melo Suzanne L Doyle Emma Foley John V Reynolds Aideen Long Joanne Lysaght

Front Immunol 2018 13;9:1867. Epub 2018 Aug 13.

Department of Surgery, St. James's Hospital, Trinity College Dublin, Trinity Translational Medicine Institute, Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2018.01867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099201PMC
September 2019

Differential Expression Profiles of Oxidative Stress Levels, 8-oxo-dG and 4-HNE, in Barrett's Esophagus Compared to Esophageal Adenocarcinoma.

Authors:
Naoimh J O'Farrell James J Phelan Ronan Feighery Brendan Doyle Sarah L Picardo Narayanasamy Ravi Dermot O'Toole John V Reynolds Jacintha O'Sullivan

Int J Mol Sci 2019 Sep 10;20(18). Epub 2019 Sep 10.

Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James' Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.3390/ijms20184449DOI Listing
September 2019

Physical recovery in the first six months following oesophago-gastric cancer surgery. Identifying rehabilitative needs: a qualitative interview study.

Authors:
Linda O'Neill Annemarie E Bennett Emer Guinan John V Reynolds Juliette Hussey

Disabil Rehabil 2019 Sep 16:1-8. Epub 2019 Sep 16.

Discipline of Physiotherapy, School of Medicine, Trinity College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.1080/09638288.2019.1663946DOI Listing
September 2019

Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma.

Authors:
Becky A S Bibby Cecelia S Miranda John V Reynolds Christopher J Cawthorne Stephen G Maher

BMC Cancer 2019 Aug 7;19(1):784. Epub 2019 Aug 7.

Cancer Biology and Therapeutics Lab, School of Life Sciences, University of Hull, Hull, HU6 7RX, UK.

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http://dx.doi.org/10.1186/s12885-019-5996-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686260PMC
August 2019

A pilot study of the impact of Vitamin C supplementation with neoadjuvant chemoradiation on regulators of inflammation and carcinogenesis in esophageal cancer patients.

Authors:
Mohamed M M Abdel-Latif Mawash Babar Dermot Kelleher John V Reynolds

J Cancer Res Ther 2019 Jan-Mar;15(1):185-191

Department of Clinical Surgery, Trinity Centre for Health Sciences, St. James's Hospital and Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.4103/jcrt.JCRT_763_16DOI Listing
July 2019

Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma.

Authors:
Ashanty M Melo Aisling M O'Brien James J Phelan Susan A Kennedy Nicole A W Wood Natacha Veerapen Gurdyal S Besra Niamh E Clarke Emma K Foley Akshaya Ravi Finbar MacCarthy Dermot O'Toole Narayamasami Ravi John V Reynolds Melissa J Conroy Andrew E Hogan Jacintha O'Sullivan Margaret R Dunne

Front Immunol 2019 10;10:1580. Epub 2019 Jul 10.

Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2019.01580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635552PMC
July 2019

Pyrazinib (P3), [(E)-2-(2-Pyrazin-2-yl-vinyl)-phenol], a small molecule pyrazine compound enhances radiosensitivity in oesophageal adenocarcinoma.

Authors:
Amy M Buckley Margaret R Dunne Niamh Lynam-Lennon Susan A Kennedy Aoife Cannon Alison L Reynolds Stephen G Maher John V Reynolds Breandán N Kennedy Jacintha O'Sullivan

Cancer Lett 2019 Apr 19;447:115-129. Epub 2019 Jan 19.

Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Trinity College Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835193002
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http://dx.doi.org/10.1016/j.canlet.2019.01.009DOI Listing
April 2019

Altered T Cell Migratory Capacity in the Progression from Barrett Oesophagus to Oesophageal Adenocarcinoma.

Authors:
Maria E Kavanagh Melissa J Conroy Niamh E Clarke Niamh T Gilmartin Ronan Feighery Finbar MacCarthy Dermot O'Toole Narayanasamy Ravi John V Reynolds Jacintha O' Sullivan Joanne Lysaght

Cancer Microenviron 2019 Apr 4;12(1):57-66. Epub 2019 Mar 4.

Department of Surgery, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/s12307-019-00220-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529503PMC
April 2019

Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma.

Authors:
Ann Marie Mongan Niamh Lynam-Lennon Suzanne L Doyle Rory Casey Eibhlin Carr Aoife Cannon Melissa J Conroy Graham P Pidgeon Lorraine Brennan Joanne Lysaght John V Reynolds Jacintha O'Sullivan

Int J Med Sci 2019 5;16(4):519-528. Epub 2019 Apr 5.

Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.7150/ijms.29296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535661PMC
April 2019

Benchmarking Complications Associated with Esophagectomy.

Authors:
Donald E Low Madhan Kumar Kuppusamy Derek Alderson Ivan Cecconello Andrew C Chang Gail Darling Andrew Davies Xavier Benoit D'Journo Suzanne S Gisbertz S Michael Griffin Richard Hardwick Arnulf Hoelscher Wayne Hofstetter Blair Jobe Yuko Kitagawa Simon Law Christophe Mariette Nick Maynard Christopher R Morse Philippe Nafteux Manuel Pera C S Pramesh Sonia Puig John V Reynolds Wolfgang Schroeder Mark Smithers B P L Wijnhoven

Ann Surg 2019 Feb;269(2):291-298

Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/SLA.0000000000002611DOI Listing
February 2019

Attenuation of satiety gut hormones increases appetitive behavior after curative esophagectomy for esophageal cancer.

Authors:
Jessie A Elliott Neil G Docherty Jacqueline Haag Hans-Georg Eckhardt Narayanasamy Ravi John V Reynolds Carel W le Roux

Am J Clin Nutr 2019 02;109(2):335-344

Metabolic Medicine, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1093/ajcn/nqy324DOI Listing
February 2019

International consensus on a complications list after gastrectomy for cancer.

Authors:
Gian Luca Baiocchi Simone Giacopuzzi Daniele Marrelli Daniel Reim Guillaume Piessen Paulo Matos da Costa John V Reynolds Hans-Joachim Meyer Paolo Morgagni Ines Gockel Lucio Lara Santos Lone Susanne Jensen Thomas Murphy Shaun R Preston Mikhail Ter-Ovanesov Uberto Fumagalli Romario Maurizio Degiuli Wojciech Kielan Stefan Mönig Piotr Kołodziejczyk Wojciech Polkowski Richard Hardwick Manuel Pera Jan Johansson Paul M Schneider Wobbe O de Steur Suzanne S Gisbertz Henk Hartgrink Joanna W van Sandick Nazario Portolani Arnulf H Hölscher Maristella Botticini Franco Roviello Christophe Mariette William Allum Giovanni De Manzoni

Gastric Cancer 2019 01 30;22(1):172-189. Epub 2018 May 30.

Department of Surgery, General and Upper G.I. Surgery Division, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1007/s10120-018-0839-5DOI Listing
January 2019

Risk factors for loss of bone mineral density after curative esophagectomy.

Authors:
Jessie A Elliott Sean Casey Conor F Murphy Neil G Docherty Narayanasamy Ravi Peter Beddy John V Reynolds Carel W le Roux

Arch Osteoporos 2019 Jan 9;14(1). Epub 2019 Jan 9.

Metabolic Medicine, University College Dublin, Conway Institute of Biomedical and Biomolecular Research, Dublin 4, Ireland.

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http://link.springer.com/10.1007/s11657-018-0556-z
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http://dx.doi.org/10.1007/s11657-018-0556-zDOI Listing
January 2019

Can the Efficacy of [F]FDG-PET/CT in Clinical Oncology Be Enhanced by Screening Biomolecular Profiles?

Authors:
Hazel O'Neill Vinod Malik Ciaran Johnston John V Reynolds Jacintha O'Sullivan

Pharmaceuticals (Basel) 2019 Jan 23;12(1). Epub 2019 Jan 23.

Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, D08W9RT Dublin, Ireland.

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http://dx.doi.org/10.3390/ph12010016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469153PMC
January 2019

The RESTORE Randomized Controlled Trial: Impact of a Multidisciplinary Rehabilitative Program on Cardiorespiratory Fitness in Esophagogastric cancer Survivorship.

Authors:
Linda M O'Neill Emer Guinan Suzanne L Doyle Annemarie E Bennett Conor Murphy Jessie A Elliott Jacintha OʼSullivan John V Reynolds Juliette Hussey

Ann Surg 2018 11;268(5):747-755

Discipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1097/SLA.0000000000002895DOI Listing
November 2018

Toward a Consensus on Centralization in Surgery.

Authors:
René Vonlanthen Peter Lodge Jeffrey S Barkun Olivier Farges Xavier Rogiers Kjetil Soreide Henrik Kehlet John V Reynolds Samuel A Käser Peter Naredi Inne Borel-Rinkes Sebastiano Biondo Hugo Pinto-Marques Michael Gnant Philippe Nafteux Miroslav Ryska Wolf O Bechstein Guillaume Martel Justin B Dimick Marek Krawczyk Attila Oláh Antonio D Pinna Irinel Popescu Pauli A Puolakkainen Georgius C Sotiropoulos Erkki J Tukiainen Henrik Petrowsky Pierre-Alain Clavien

Ann Surg 2018 11;268(5):712-724

Department of Surgery and Transplantation, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/SLA.0000000000002965DOI Listing
November 2018

Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments.

Authors:
Jacintha O'Sullivan Joanne Lysaght Claire L Donohoe John V Reynolds

Nat Rev Gastroenterol Hepatol 2018 11;15(11):699-714

Trinity Translational Medicine Institute, Trinity College Dublin and St. James's Hospital, Dublin, Ireland.

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http://www.nature.com/articles/s41575-018-0069-7
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http://dx.doi.org/10.1038/s41575-018-0069-7DOI Listing
November 2018

The Mitochondrial Genes , and are Linked with Alterations in Mitochondrial Membrane Potential in Barrett's Esophagus.

Authors:
James J Phelan Finbar MacCarthy Dermot O'Toole Narayanasamy Ravi John V Reynolds Jacintha O'Sullivan

Int J Mol Sci 2018 Nov 6;19(11). Epub 2018 Nov 6.

Trinity Translational Medicine Institute, Department of Surgery, St. James's Hospital, D08W9RT Dublin, Ireland.

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http://dx.doi.org/10.3390/ijms19113483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275077PMC
November 2018

Leukaemia inhibitory factor is associated with treatment resistance in oesophageal adenocarcinoma.

Authors:
Amy M Buckley Niamh Lynam-Lennon Susan A Kennedy Margaret R Dunne John J Aird Emma K Foley Niamh Clarke Narayanasamy Ravi Dermot O'Toole John V Reynolds Breandán N Kennedy Jacintha O'Sullivan

Oncotarget 2018 Sep 14;9(72):33634-33647. Epub 2018 Sep 14.

Department of Surgery, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.

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http://www.oncotarget.com/fulltext/25950
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http://dx.doi.org/10.18632/oncotarget.25950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154751PMC
September 2018

Physical decline and its implications in the management of oesophageal and gastric cancer: a systematic review.

Authors:
Linda O'Neill Jonathan Moran Emer M Guinan John V Reynolds Juliette Hussey

J Cancer Surviv 2018 08 23;12(4):601-618. Epub 2018 May 23.

Discipline of Physiotherapy, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1007/s11764-018-0696-6DOI Listing
August 2018

pSTAT3 Levels Have Divergent Expression Patterns and Associations with Survival in Squamous Cell Carcinoma and Adenocarcinoma of the Oesophagus.

Authors:
Katie E O' Sullivan Adriana J Michielsen Esther O' Regan Mary C Cathcart Gillian Moore Eamon Breen Ricardo Segurado John V Reynolds Joanne Lysaght Jacintha O' Sullivan

Int J Mol Sci 2018 Jun 10;19(6). Epub 2018 Jun 10.

Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.3390/ijms19061720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032321PMC
June 2018

Outcomes for Esophageal Squamous Cell Carcinoma Treated with Curative Intent in a Western Cohort: Should Multimodal Therapy Be the Gold Standard?

Authors:
Fiachra Sheil Claire L Donohoe Sinéad King Dermot O'Toole Moya Cunningham Sinéad Cuffe Narayanasamy Ravi John V Reynolds

World J Surg 2018 05;42(5):1485-1495

Department of Surgery, St. James's Hospital, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1007/s00268-017-4289-8DOI Listing
May 2018

Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma.

Authors:
Karen C Galvin Melissa J Conroy Suzanne L Doyle Margaret R Dunne Ronan Fahey Emma Foley Katie E O'Sullivan Derek G Doherty Justin G Geoghegan Narayanasamy Ravi Cliona O'Farrelly John V Reynolds Joanne Lysaght

Cancer Lett 2018 04 12;418:230-238. Epub 2018 Jan 12.

Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.01.039DOI Listing
April 2018

siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth.

Authors:
Shane P Duggan Catherine Garry Fiona M Behan Sinead Phipps Hiromi Kudo Murat Kirca Abdul Zaheer Sarah McGarrigle John V Reynolds Robert Goldin Steve E Kalloger David F Schaeffer Aideen Long Jessica Strid Dermot Kelleher

Cell Mol Gastroenterol Hepatol 2018 31;5(4):569-590. Epub 2018 Jan 31.

Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jcmgh.2018.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009761PMC
January 2018

Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin-αv trafficking.

Authors:
David O Prichard Anne Marie Byrne James O Murphy John V Reynolds Jacintha O'Sullivan Ronan Feighery Brendan Doyle Osama Sharaf Eldin Stephen P Finn Aoife Maguire Deirdre Duff Dermot P Kelleher Aideen Long

J Cell Mol Med 2017 Dec 22;21(12):3612-3625. Epub 2017 Sep 22.

Cell and Molecular Biology Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1111/jcmm.13271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706496PMC
December 2017

Multidisciplinary rehabilitation across the esophageal cancer journey.

Authors:
Linda O'Neill Jenny Gannon Emer Guinan John V Reynolds Juliette Hussey

J Thorac Dis 2017 Dec;9(12):E1140-E1142

Discipline of Physiotherapy, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.21037/jtd.2017.11.72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757004PMC
December 2017

Does Prolonged Enteral Feeding With Supplemental Omega-3 Fatty Acids Impact on Recovery Post-esophagectomy: Results of a Randomized Double-Blind Trial.

Authors:
Laura A Healy Aoife Ryan Suzanne L Doyle Éadaoin Bríd Ní Bhuachalla Samantha Cushen Ricardo Segurado Thomas Murphy Narayanasamy Ravi Claire L Donohoe John V Reynolds

Ann Surg 2017 11;266(5):720-728

*National Esophageal Center, St James Hospital, Dublin, Ireland †Clinical Nutrition, St James Hospital, Dublin, Ireland ‡School of Food & Nutritional Sciences, University College Cork, Cork, Ireland §School of Biological Sciences, Dublin Institute of Technology, Dublin, Ireland ¶Centre for Support and Training in Analysis and Research (CSTAR), University College Dublin, Dublin, Ireland ||Dept of Surgery, Mercy University Hospital, Cork, Ireland.

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http://dx.doi.org/10.1097/SLA.0000000000002390DOI Listing
November 2017

Sarcopenia: Prevalence, and Impact on Operative and Oncologic Outcomes in the Multimodal Management of Locally Advanced Esophageal Cancer.

Authors:
Jessie A Elliott Suzanne L Doyle Conor F Murphy Sinead King Emer M Guinan Peter Beddy Narayanasamy Ravi John V Reynolds

Ann Surg 2017 11;266(5):822-830

*Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin, and St. James's Hospital, Dublin, Ireland †School of Biological Sciences, Dublin Institute of Technology, Dublin, Ireland ‡School of Medicine, Trinity College Dublin, Dublin, Ireland §Department of Radiology, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/SLA.0000000000002398DOI Listing
November 2017

Weight Loss, Satiety, and the Postprandial Gut Hormone Response After Esophagectomy: A Prospective Study.

Authors:
Jessie A Elliott Neil G Docherty Hans-Georg Eckhardt Suzanne L Doyle Emer M Guinan Narayanasamy Ravi John V Reynolds Carel W le Roux

Ann Surg 2017 07;266(1):82-90

*Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St James's Hospital, Dublin 8, Ireland †Diabetes Complications Research Centre, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin 4, Ireland ‡Gastrosurgical Laboratory, Sahlgrenska Academy, University of Gothenburg, Sweden.

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http://Insights.ovid.com/crossref?an=00000658-201707000-0001
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http://dx.doi.org/10.1097/SLA.0000000000001918DOI Listing
July 2017

HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients.

Authors:
Margaret R Dunne Adriana J Michielsen Katie E O'Sullivan Mary Clare Cathcart Ronan Feighery Brendan Doyle Jenny A Watson Naoimh J O'Farrell Narayanasamy Ravi Elaine Kay John V Reynolds Elizabeth J Ryan Jacintha O'Sullivan

Cancer Immunol Immunother 2017 Jul 18;66(7):841-850. Epub 2017 Mar 18.

Department of Surgery, St. James's Hospital, Trinity Translational Medicine Institute, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/s00262-017-1983-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489642PMC
July 2017

Neoadjuvant treatment of locally advanced esophageal and junctional cancer: the evidence-base, current key questions and clinical trials.

Authors:
Claire L Donohoe John V Reynolds

J Thorac Dis 2017 Jul;9(Suppl 8):S697-S704

Department of Surgery, St. James's Hospital and Trinity College Dublin, Ireland.

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http://dx.doi.org/10.21037/jtd.2017.03.159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538972PMC
July 2017

Effects of a multimodal rehabilitation programme on inflammation and oxidative stress in oesophageal cancer survivors: the ReStOre feasibility study.

Authors:
Emer M Guinan Suzanne L Doyle Linda O'Neill Margaret R Dunne Emma K Foley Jacintha O'Sullivan John V Reynolds Juliette Hussey

Support Care Cancer 2017 03 3;25(3):749-756. Epub 2016 Nov 3.

Discipline of Physiotherapy, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1007/s00520-016-3455-0DOI Listing
March 2017

Risk Factors for Anastomotic Stricture Post-esophagectomy with a Standardized Sutured Anastomosis.

Authors:
Zuhair Ahmed Jessie A Elliott Sinead King Claire L Donohoe Narayanasamy Ravi John V Reynolds

World J Surg 2017 Feb;41(2):487-497

Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/s00268-016-3746-0DOI Listing
February 2017

Metabolic tumor volume provides complementary prognostic information to EUS staging in esophageal and junctional cancer.

Authors:
Vinod Malik Ciaran Johnston Dermot O'Toole Julie Lucey Naoimh O'Farrell Zieta Claxton John V Reynolds

Dis Esophagus 2017 Feb;30(3):1-8

Department of Clinical Surgery, St James's Hospital and Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1111/dote.12505DOI Listing
February 2017

MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype.

Authors:
Niamh Lynam-Lennon Susan Heavey Gary Sommerville Becky A S Bibby Brendan Ffrench Jennifer Quinn Claudia Gasch John J O'Leary Michael F Gallagher John V Reynolds Stephen G Maher

Oncotarget 2017 Feb;8(7):11400-11413

Trinity Translational Medicine Institute, Department of Surgery, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.18632/oncotarget.13940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355274PMC
February 2017

Emerging Concepts Linking Obesity with the Hallmarks of Cancer.

Authors:
Claire L Donohoe Joanne Lysaght Jacintha O'Sullivan John V Reynolds

Trends Endocrinol Metab 2017 01 12;28(1):46-62. Epub 2016 Sep 12.

Department of Surgery, Trinity Translational Medicine Institute (TTMI), Trinity College Dublin/St James' Hospital, Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10432760163010
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http://dx.doi.org/10.1016/j.tem.2016.08.004DOI Listing
January 2017

Home enteral nutrition recipients: patient perspectives on training, complications and satisfaction.

Authors:
Karen Boland Niamh Maher Carmel O'Hanlon Maria O'Sullivan Niamh Rice Martina Smyth John V Reynolds

Frontline Gastroenterol 2017 Jan 8;8(1):79-84. Epub 2016 Oct 8.

Department of Nutrition and Dietetics, Beaumont Hospital, Dublin 9, Ireland; Trinity Centre, St James Hospital, Dublin 8, Ireland; Department of Surgery, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1136/flgastro-2016-100736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256397PMC
January 2017

Factors regulating nuclear factor-kappa B activation in esophageal cancer cells: Role of bile acids and acid.

Authors:
Mohamed Mahmoud M Abdel-Latif Hiroyasu Inoue Dermot Kelleher John V Reynolds

J Cancer Res Ther 2016 Jan-Mar;12(1):364-73

Department of Surgery, Trinity Centre for Health Sciences, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.4103/0973-1482.174525DOI Listing
December 2016

The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function.

Authors:
Melissa J Conroy Vivienne Fitzgerald Suzanne L Doyle Shauna Channon Zivile Useckaite Niamh Gilmartin Cliona O'Farrelly Narayanasamy Ravi John V Reynolds Joanne Lysaght

J Leukoc Biol 2016 12 30;100(6):1435-1442. Epub 2016 Jun 30.

Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Trinity College Dublin, Ireland;

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http://dx.doi.org/10.1189/jlb.5AB1115-493RRDOI Listing
December 2016

Can CT-PET and Endoscopic Assessment Post-Neoadjuvant Chemoradiotherapy Predict Residual Disease in Esophageal Cancer?

Authors:
Helen M Heneghan Claire Donohoe Jessie Elliot Zuhair Ahmed Vinod Malik Narayamasamy Ravi John V Reynolds

Ann Surg 2016 Nov;264(5):831-838

Department of Surgery, Trinity Healthcare Sciences Building, St. James's Hospital and Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1097/SLA.0000000000001902DOI Listing
November 2016

Physiology, pathophysiology and therapeutic implications of enteroendocrine control of food intake.

Authors:
Jessie A Elliott John V Reynolds Carel W le Roux Neil G Docherty

Expert Rev Endocrinol Metab 2016 Nov 20;11(6):475-499. Epub 2016 Oct 20.

a Diabetes Complications Research Centre, Conway Institute of Biomedical and Biomolecular Research , University College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.1080/17446651.2016.1245140DOI Listing
November 2016

Parallel Profiles of Inflammatory and Effector Memory T Cells in Visceral Fat and Liver of Obesity-Associated Cancer Patients.

Authors:
Melissa J Conroy Karen C Galvin Suzanne L Doyle Maria E Kavanagh Ann-Marie Mongan Aoife Cannon Gillian Y Moore John V Reynolds Joanne Lysaght

Inflammation 2016 Oct;39(5):1729-36

Department of Surgery, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/s10753-016-0407-2DOI Listing
October 2016

Corrigendum: The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

Authors:
Shane P Duggan Fiona M Behan Murat Kirca Abdul Zaheer Sarah A McGarrigle John V Reynolds Gisela M F Vaz Mathias O Senge Dermot Kelleher

Sci Rep 2016 10 14;6:35330. Epub 2016 Oct 14.

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http://dx.doi.org/10.1038/srep35330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064320PMC
October 2016

Docemur Docemus: Peer-Assisted Learning Improves the Knowledge Gain of Tutors in the Highest Quartile of Achievement but Not Those in the Lowest Quartile.

Authors:
Claire L Donohoe John B Conneely Nathan Zilbert Martina Hennessy Susie Schofield John V Reynolds

J Surg Educ 2015 Nov-Dec;72(6):1139-44. Epub 2015 Aug 10.

Department of Surgery, St. James's Hospital and Trinity College Dublin, Dublin, Ireland. Electronic address:

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September 2016

Opposing effects of bile acids deoxycholic acid and ursodeoxycholic acid on signal transduction pathways in oesophageal cancer cells.

Authors:
Mohamed M Abdel-Latif Hiroyasu Inoue John V Reynolds

Eur J Cancer Prev 2016 09;25(5):368-79

aDepartment of Clinical Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt bDepartment of Pharmacology, National Cardiovascular Center Research Institute, Suita, Osaka, Japan cDepartment of Clinical Surgery, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland.

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September 2016

The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.

Authors:
Shane P Duggan Fiona M Behan Murat Kirca Abdul Zaheer Sarah A McGarrigle John V Reynolds Gisela M F Vaz Mathias O Senge Dermot Kelleher

Sci Rep 2016 09 2;6:32638. Epub 2016 Sep 2.

Department of Medicine, Division of Gastroenterology, University of British Columbia, 2775 Laurel Street, Vancouver, British Columbia, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009315PMC
September 2016

CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer.

Authors:
Melissa J Conroy Karen C Galvin Maria E Kavanagh Ann Marie Mongan Suzanne L Doyle Niamh Gilmartin Cliona O'Farrelly John V Reynolds Joanne Lysaght

Immunol Cell Biol 2016 07 5;94(6):531-7. Epub 2016 Apr 5.

Department of Surgery, Trinity College Dublin, Dublin, Ireland.

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July 2016

Does the modified Glasgow Prognostic Score (mGPS) have a prognostic role in esophageal cancer?

Authors:
Siun M Walsh Sarah Casey Raymond Kennedy Narayanasamy Ravi John V Reynolds

J Surg Oncol 2016 Jun 23;113(7):732-7. Epub 2016 Mar 23.

National Centre for Esophageal and Gastric Cancer, St. James's Hospital, Dublin, Ireland.

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http://doi.wiley.com/10.1002/jso.24225
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June 2016

MicroRNA-330-5p as a Putative Modulator of Neoadjuvant Chemoradiotherapy Sensitivity in Oesophageal Adenocarcinoma.

Authors:
Becky A S Bibby John V Reynolds Stephen G Maher

PLoS One 2015 29;10(7):e0134180. Epub 2015 Jul 29.

School of Biological, Biomedical and Environmental Sciences, University of Hull, Hull, United States of America; Department of Surgery, Institute of Molecular Medicine, Trinity College Dublin, St. James Hospital, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519309PMC
May 2016

Obesity-associated cancer: an immunological perspective.

Authors:
Melissa J Conroy Margaret R Dunne Claire L Donohoe John V Reynolds

Proc Nutr Soc 2016 May 16;75(2):125-38. Epub 2015 Nov 16.

Dept. Surgery,Trinity Centre for Health Sciences,St. James's Hospital and Trinity College Dublin,Dublin 8,Ireland.

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http://dx.doi.org/10.1017/S0029665115004176DOI Listing
May 2016

Pancreatic Aetiology for Massive Upper Gastrointestinal Haemorrhage in Pregnancy.

Authors:
Alexandra Zaborowski Siun M Walsh Narayanasamy Ravi John V Reynolds

Case Rep Surg 2016 29;2016:5491851. Epub 2016 Feb 29.

Department of Surgery, Trinity Centre, St. James's Hospital, James's Street, Dublin 8, Ireland.

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http://dx.doi.org/10.1155/2016/5491851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789407PMC
April 2016

Impact of the inflammatory microenvironment on T-cell phenotype in the progression from reflux oesophagitis to Barrett oesophagus and oesophageal adenocarcinoma.

Authors:
Maria E Kavanagh Melissa J Conroy Niamh E Clarke Niamh T Gilmartin Katie E O'Sullivan Ronan Feighery Finbar MacCarthy Dermot O'Toole Narayanasamy Ravi John V Reynolds Jacintha O'Sullivan Joanne Lysaght

Cancer Lett 2016 Jan 28;370(1):117-24. Epub 2015 Oct 28.

Department of Surgery, Institute of Molecular Medicine, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland. Electronic address:

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January 2016

Letter to the Co-Editors-in-Chief, Radiotherapy and Oncology.

Authors:
Claire L Donohoe John V Reynolds

Radiother Oncol 2016 Jan 4;118(1):215. Epub 2016 Jan 4.

Dept. of Surgery, Trinity College Dublin/St James' Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.radonc.2015.12.010DOI Listing
January 2016

Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion.

Authors:
Anne-Marie Byrne Spiros Bekiaris Gina Duggan David Prichard Murat Kirca Stephen Finn John V Reynolds Dermot Kelleher Aideen Long

Br J Cancer 2015 Nov 13;113(9):1332-42. Epub 2015 Oct 13.

Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College, Dublin D08W9RT, Ireland.

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http://dx.doi.org/10.1038/bjc.2015.350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815786PMC
November 2015

Successful surgical management of early esophageal cancer in a patient with cystic fibrosis post-bilateral lung transplantation.

Authors:
Siun M Walsh Nomsa Maphango Jim J Egan John V Reynolds

BMJ Case Rep 2015 Nov 3;2015. Epub 2015 Nov 3.

St James's Hospital, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654142PMC
November 2015

Prospective Study of Malabsorption and Malnutrition After Esophageal and Gastric Cancer Surgery.

Authors:
Helen M Heneghan Alexandra Zaborowski Michelle Fanning Aisling McHugh Suzanne Doyle Jenny Moore Nayarasamy Ravi John V Reynolds

Ann Surg 2015 Nov;262(5):803-7; discussion 807-8

Department of Surgery, Trinity College Dublin, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland.

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November 2015

Gut Hormone Suppression Increases Food Intake After Esophagectomy With Gastric Conduit Reconstruction.

Authors:
Jessie A Elliott Sabrina Jackson Sinead King Ruth McHugh Neil G Docherty John V Reynolds Carel W le Roux

Ann Surg 2015 Nov;262(5):824-29; discussion 829-30

*Diabetes Complications Research Centre, Conway Institute of Biomedical and Biomolecular Research, University College Dublin, Dublin, Ireland †Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin and St. James's Hospital, Dublin, Ireland ‡Wellcome Trust and HRB Clinical Research Facility, St. James's Hospital, Dublin, Ireland §Gastrosurgical Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenberg, Sweden.

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November 2015

Diffuse oesophageal leiomyomatosis.

Authors:
Gabriella Guevara Eabhann O'Connor Orla McCormack Mark Harmon Stephen Finn Cian Muldoon Narayanasamy Ravi John V Reynolds

ANZ J Surg 2015 Sep 16;85(9):685-6. Epub 2013 Dec 16.

Department of Surgery, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1111/ans.12492DOI Listing
September 2015

Obesity and increased risk of esophageal adenocarcinoma.

Authors:
Jessie A Elliott Claire L Donohoe John V Reynolds

Expert Rev Endocrinol Metab 2015 Sep 9;10(5):511-523. Epub 2015 Aug 9.

a 1 Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin & St. James' Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1586/17446651.2015.1077696DOI Listing
September 2015

International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG).

Authors:
Donald E Low Derek Alderson Ivan Cecconello Andrew C Chang Gail E Darling Xavier Benoit DʼJourno S Michael Griffin Arnulf H Hölscher Wayne L Hofstetter Blair A Jobe Yuko Kitagawa John C Kucharczuk Simon Ying Kit Law Toni E Lerut Nick Maynard Manuel Pera Jeffrey H Peters C S Pramesh John V Reynolds B Mark Smithers J Jan B van Lanschot

Ann Surg 2015 Aug;262(2):286-94

*Virginia Mason Medical Center, Seattle, WA †University of Birmingham, Birmingham, United Kingdom ‡University of São Paulo, School of Medicine, São Paulo, Brazil §University of Michigan Health System, Ann Arbor, MI ¶Toronto General Hospital, Toronto, Ontario, Canada ‖Sainte Marguerite Hospital, Marseille, France **University of Newcastle upon Tyne, Newcastle, United Kingdom ††University of Cologne, Cologne, Germany ‡‡MD Anderson Cancer Center, Houston, TX §§Allegheny Health Network's Esophageal and Thoracic Institute, Pittsburgh, PA ¶¶Keio University, Tokyo, Japan ‖‖University of Pennsylvania, Philadelphia, PA ***Queen Mary Hospital, Hong Kong SAR, China †††Katholieke Universiteit Leuven, Leuven, Belgium ‡‡‡Oxford Radcliffe Hospitals, Oxford, United Kingdom §§§Hospital Universitario del Mar, Barcelona, Spain ¶¶¶University of Rochester Surgery, Rochester, NY ‖‖‖Tata Hospital, Mumbai, India ****Trinity College Dublin, Dublin, Ireland ††††Princess Alexandra Hospital, The University of Queensland, Brisbane, Australia ‡‡‡‡Erasmus Medical Center, Rotterdam, The Netherlands.

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August 2015

Oesophageal perforations commentary.

Authors:
Claire L Donohoe John V Reynolds

Dig Surg 2013 10;30(1):26-7. Epub 2013 Apr 10.

Department of Surgery, Trinity College Dublin, St James' Hospital, Dublin, Ireland.

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May 2015

Molecular mechanisms of constitutive and inducible NF-kappaB activation in oesophageal adenocarcinoma.

Authors:
Mohamed M M Abdel-Latif Dermot Kelleher John V Reynolds

Eur J Cancer 2015 Mar 14;51(4):464-72. Epub 2015 Jan 14.

Department of Surgery, Trinity Centre for Health Sciences, St. James's Hospital, Dublin 8, Ireland. Electronic address:

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March 2015

Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma.

Authors:
Niamh Lynam-Lennon Stephen G Maher Aoife Maguire James Phelan Cian Muldoon John V Reynolds Jacintha O'Sullivan

PLoS One 2014 26;9(6):e100738. Epub 2014 Jun 26.

Department of Surgery, Trinity College Dublin, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072695PMC
February 2015

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.

Authors:
Claire Palles Laura Chegwidden Xinzhong Li John M Findlay Garry Farnham Francesc Castro Giner Maikel P Peppelenbosch Michal Kovac Claire L Adams Hans Prenen Sarah Briggs Rebecca Harrison Scott Sanders David MacDonald Chris Haigh Art Tucker Sharon Love Manoj Nanji John deCaestecker David Ferry Barrie Rathbone Julie Hapeshi Hugh Barr Paul Moayyedi Peter Watson Barbara Zietek Neera Maroo Laura Gay Tim Underwood Lisa Boulter Hugh McMurtry David Monk Praful Patel Krish Ragunath David Al Dulaimi Iain Murray Konrad Koss Andrew Veitch Nigel Trudgill Chuka Nwokolo Bjorn Rembacken Paul Atherfold Elaine Green Yeng Ang Ernst J Kuipers Wu Chow Stuart Paterson Sudarshan Kadri Ian Beales Charles Grimley Paul Mullins Conrad Beckett Mark Farrant Andrew Dixon Sean Kelly Matthew Johnson Shahjehan Wajed Anjan Dhar Elinor Sawyer Rebecca Roylance Lynn Onstad Marilie D Gammon Douglas A Corley Nicholas J Shaheen Nigel C Bird Laura J Hardie Brian J Reid Weimin Ye Geoffrey Liu Yvonne Romero Leslie Bernstein Anna H Wu Alan G Casson Rebecca Fitzgerald David C Whiteman Harvey A Risch David M Levine Tom L Vaughan Auke P Verhaar Jan van den Brande Eelke L Toxopeus Manon C Spaander Bas P L Wijnhoven Luc J W van der Laan Kausilia Krishnadath Cisca Wijmenga Gosia Trynka Ross McManus John V Reynolds Jacintha O'Sullivan Padraic MacMathuna Sarah A McGarrigle Dermot Kelleher Severine Vermeire Isabelle Cleynen Raf Bisschops Ian Tomlinson Janusz Jankowski

Gastroenterology 2015 Feb 5;148(2):367-78. Epub 2014 Nov 5.

University Hospitals Coventry & Warwickshire NHS Trust, Warwickshire, England; Warwick Medical School, University of Warwick, Warwickshire, England. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315134PMC
February 2015

Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma.

Authors:
Niamh Lynam-Lennon Ruth Connaughton Eibhlin Carr Ann-Marie Mongan Naoimh J O'Farrell Richard K Porter Lorraine Brennan Graham P Pidgeon Joanne Lysaght John V Reynolds Jacintha O'Sullivan

BMC Cancer 2014 Dec 3;14:907. Epub 2014 Dec 3.

Department of Surgery, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265417PMC
December 2014

New-onset atrial fibrillation post-surgery for esophageal and junctional cancer: incidence, management, and impact on short- and long-term outcomes.

Authors:
Orla Mc Cormack Alex Zaborowski Sinead King Laura Healy Caroline Daly Naoimh OʼFarrell Claire L Donohoe Narayanasamy Ravi John V Reynolds

Ann Surg 2014 Nov;260(5):772-8; discussion 778

From the National Esophageal and Gastric Cancer Center, Trinity College Dublin, and St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/SLA.0000000000000960DOI Listing
November 2014

The role of inflammation in cancer of the esophagus.

Authors:
Katie E O'Sullivan James J Phelan Ciara O'Hanlon Joanne Lysaght Jacintha N O'Sullivan John V Reynolds

Expert Rev Gastroenterol Hepatol 2014 Sep 23;8(7):749-60. Epub 2014 May 23.

Department of Surgery, Institute of Molecular Medicine, St. James Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1586/17474124.2014.913478DOI Listing
September 2014

Images in clinical medicine. Intermittent facial flushing and diarrhea.

Authors:
Orla Mc Cormack John V Reynolds

N Engl J Med 2014 Jul;371(3):260

St. James's Hospital, Dublin, Ireland

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http://dx.doi.org/10.1056/NEJMicm1314969DOI Listing
July 2014

Defining a successful esophagectomy.

Authors:
Claire L Donohoe John V Reynolds

Ann Surg 2014 May;259(5):e82

Trinity College Dublin, Ireland St James's Hospital Trinity Center for Health Sciences Dublin, Ireland

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May 2014

Eosinophilic ascites with marked peripheral eosinophilia: a diagnostic challenge.

Authors:
Jessie A Elliott Orla McCormack Nairi Tchrakian Niall Conlon Ciara E Ryan Kheng Tian Lim Naeem Ullah Nasir Mahmud Narayanasamy Ravi Susan McKiernan Conleth Feighery John V Reynolds

Eur J Gastroenterol Hepatol 2014 Apr;26(4):478-84

aDepartment of Surgery, Trinity Centre, St James's Hospital and Trinity College bDepartment of Pathology cDepartment of Immunology dDepartment of Gastroenterology, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/MEG.0000000000000037DOI Listing
April 2014

Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (PREPARE study): study protocol for a randomized controlled trial.

Authors:
Karin Valkenet Jaap Ca Trappenburg Rik Gosselink Meindert N Sosef Jerome Willms Camiel Rosman Heleen Pieters Joris Jg Scheepers Saskia C de Heus John V Reynolds Emer Guinan Jelle P Ruurda Els He Rodrigo Philippe Nafteux Marianne Fontaine Ewout A Kouwenhoven Margot Kerkemeyer Donald L van der Peet Sylvia W Hania Richard van Hillegersberg Frank Jg Backx

Trials 2014 Apr 27;15:144. Epub 2014 Apr 27.

Department of Rehabilitation, Nursing Science and Sports, University Medical Center Utrecht, PO Box 85500, Utrecht 3508 GA, The Netherlands.

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http://dx.doi.org/10.1186/1745-6215-15-144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019558PMC
April 2014

Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?

Authors:
Katie E O'Sullivan John V Reynolds Ciara O'Hanlon Jacintha N O'Sullivan Joanne Lysaght

J Gastrointest Cancer 2014 Mar;45(1):1-11

Department of Surgery, Institute of Molecular Medicine, St. James Hospital, Dublin 8, Ireland,

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http://link.springer.com/10.1007/s12029-013-9555-x
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March 2014

Identification of potential therapeutic molecular targets preferentially expressed by esophageal cancer cells.

Authors:
Mutaz Mohammed Nur Stephen Finn John V Reynolds

Expert Rev Anticancer Ther 2014 Mar 12;14(3):267-9. Epub 2014 Feb 12.

Department of Histopathology, Waterford Regional Hospital, Waterford, Ireland.

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http://dx.doi.org/10.1586/14737140.2014.889790DOI Listing
March 2014

Severe dysphagia, candidiasis, and an oesophageal mass, but over 50 biopsies negative for malignancy.

Authors:
Maebh Horan Andrea Weitz Orla Mc Cormack Cian Muldoon Narayanasamy Ravi John V Reynolds

Dysphagia 2014 Feb 2;29(1):109-12. Epub 2013 Aug 2.

Department of Surgery, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1007/s00455-013-9483-8DOI Listing
February 2014

The role of obesity in gastrointestinal cancer: evidence and opinion.

Authors:
Claire L Donohoe Naoimh J O'Farrell Suzanne L Doyle John V Reynolds

Therap Adv Gastroenterol 2014 Jan;7(1):38-50

Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/ St James' Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1177/1756283X13501786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871278PMC
January 2014

Classification of pathologic response to neoadjuvant therapy in esophageal and junctional cancer: assessment of existing measures and proposal of a novel 3-point standard.

Authors:
Claire L Donohoe Naoimh J O'Farrell Tim Grant Sinead King Lindsey Clarke Cian Muldoon John V Reynolds

Ann Surg 2013 Nov;258(5):784-92; discussion 792

*Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin, and St James Hospital †Department of Biostatistics, University College Dublin ‡Department of Pathology, St James Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/SLA.0b013e3182a66588DOI Listing
November 2013

Spontaneous perforation of the esophagus in a patient with achalasia.

Authors:
Andrew R Moriarity John O Larkin Katie E O'Sullivan Narayanasamy Ravi John V Reynolds

Ann Thorac Surg 2013 Oct;96(4):1456-1457

Department of Surgery, St. James's Hospital and Trinity Center for Health Sciences, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.athoracsur.2013.01.091DOI Listing
October 2013

Cellular origins and molecular mechanisms of Barrett's esophagus and esophageal adenocarcinoma.

Authors:
Yu Fang Xiaoxin Chen Manisha Bajpai Amit Verma Kiron M Das Rhonda F Souza Katherine S Garman Claire L Donohoe Naoimh J O'Farrell John V Reynolds Katerina Dvorak

Ann N Y Acad Sci 2013 Oct;1300:187-199

Department of Cellular and Molecular Medicine, Arizona Cancer Center, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1111/nyas.12249DOI Listing
October 2013

Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus.

Authors:
Kenneth DeVault Barry P McMahon Altay Celebi Guido Costamagna Michele Marchese John O Clarke Reza A Hejazi Richard W McCallum Vincenzo Savarino Patrizia Zentilin Edoardo Savarino Mike Thomson Rhonda F Souza Claire L Donohoe Naoimh J O'Farrell John V Reynolds

Ann N Y Acad Sci 2013 Oct;1300:278-295

Trinity College Dublin/St James' Hospital, Trinity Centre for Health Sciences, St James' Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1111/nyas.12253DOI Listing
October 2013

Paraneoplastic limbic encephalitis from esophagogastric squamous cell carcinoma successfully managed by radical gastrectomy.

Authors:
Orla Mc Cormack John M Cooney Colin P Doherty Cian Muldoon John V Reynolds

Surgery 2013 Sep 7;154(3):638-40. Epub 2013 Jan 7.

Department of Surgery, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.surg.2012.11.014DOI Listing
September 2013

Appraisal of staging endoscopic ultrasonography in a modern high-volume esophageal program.

Authors:
Naoimh J O'Farrell Vinod Malik Claire L Donohoe Ciaran Johnston Cian Muldoon John V Reynolds Dermot O'Toole

World J Surg 2013 Jul;37(7):1666-72

Department of Surgery, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland.

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http://link.springer.com/10.1007/s00268-013-2004-y
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July 2013

Severe intractable postprandial chest pain.

Authors:
Conall Fitzgerald Orla Mc Cormack John V Reynolds

JAMA 2013 Jul;310(4):424-7

National Center for Esophageal and Gastric Surgery, St James's Hospital, and Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1001/jama.2013.8567DOI Listing
July 2013

Resolving sclerosing mesenteritis.

Authors:
Orla Mc Cormack James F Meaney John V Reynolds

Surgery 2013 Jun 7;153(6):879-80. Epub 2012 Jun 7.

Department of Surgery, St. James's Hospital, Dublin, Ireland; Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.surg.2012.03.027DOI Listing
June 2013

Incarcerated thoracic gastric herniation after nephrectomy: a report of two cases.

Authors:
Conall Fitzgerald Orla Mc Cormack Faisal Awan Jessie Elliott Narayanasamy Ravi John V Reynolds

Case Rep Surg 2013 16;2013:896452. Epub 2013 May 16.

Department of Surgery, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1155/2013/896452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670470PMC
June 2013

Gastric neuroendocrine tumours.

Authors:
David A Crosby Claire L Donohoe Louise Fitzgerald Cian Muldoon Brian Hayes Dermot O'Toole John V Reynolds

Dig Surg 2012 17;29(4):331-48. Epub 2012 Oct 17.

Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/St James's Hospital, Dublin, Ireland.

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May 2013

Barrett's to oesophageal cancer sequence: a model of inflammatory-driven upper gastrointestinal cancer.

Authors:
Sarah L Picardo Stephen G Maher Jacintha N O'Sullivan John V Reynolds

Dig Surg 2012 3;29(3):251-60. Epub 2012 Aug 3.

Department of Surgery, Trinity Centre for Health Sciences, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1159/000341498DOI Listing
March 2013

Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research.

Authors:
Suzanne L Doyle Anne Marie Bennett Claire L Donohoe Ann Marie Mongan Julia M Howard Fiona E Lithander Graham P Pidgeon John V Reynolds Joanne Lysaght

Nutr Res 2013 Mar 30;33(3):171-9. Epub 2013 Jan 30.

Department of Surgery, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1016/j.nutres.2012.12.007DOI Listing
March 2013

MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation.

Authors:
Emma H Allott Joanne Lysaght Mary Clare Cathcart Claire L Donohoe Robert Cummins Sarah A McGarrigle Elaine Kay John V Reynolds Graham P Pidgeon

Mol Carcinog 2013 Feb 28;52(2):144-54. Epub 2011 Nov 28.

Department of Surgery, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/mc.21840DOI Listing
February 2013

MicroRNA-31 modulates tumour sensitivity to radiation in oesophageal adenocarcinoma.

Authors:
Niamh Lynam-Lennon John V Reynolds Laure Marignol Orla M Sheils Graham P Pidgeon Stephen G Maher

J Mol Med (Berl) 2012 Dec 17;90(12):1449-58. Epub 2012 Jun 17.

Department of Surgery, Trinity College Dublin, Trinity Centre for Health Sciences, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/s00109-012-0924-xDOI Listing
December 2012

(18)F-FDG PET-detected synchronous primary neoplasms in the staging of esophageal cancer: incidence, cost, and impact on management.

Authors:
Vinod Malik Ciaran Johnston Claire Donohoe Zieta Claxton Julie Lucey Narayanasamy Ravi John V Reynolds

Clin Nucl Med 2012 Dec;37(12):1152-8

Department of Surgery, St James's Hospital and Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1097/RLU.0b013e31827083baDOI Listing
December 2012

Management of squamous cell cancer of the oesophagus in a patient with a polyglandular endocrinopathy (APECED) and achalasia.

Authors:
Orla Mc Cormack Marie Timlin Anne Mc Gowan Marie-Louise Healy Narayanasamy Ravi John V Reynolds

J Gastrointest Surg 2012 Oct 5;16(10):1963-6. Epub 2012 Apr 5.

Department of Surgery, St. James's Hospital, Dublin, and Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1007/s11605-012-1879-5DOI Listing
October 2012

The SGBS cell strain as a model for the in vitro study of obesity and cancer.

Authors:
Emma H Allott Elizabeth Oliver Joanne Lysaght Steven G Gray John V Reynolds Helen M Roche Graham P Pidgeon

Clin Transl Oncol 2012 Oct 2;14(10):774-82. Epub 2012 Aug 2.

Department of Surgery, Trinity Centre for Health Sciences, Institute of Molecular Medicine, St James' Hospital, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1007/s12094-012-0863-6DOI Listing
October 2012

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Authors:
Zhan Su Laura J Gay Amy Strange Claire Palles Gavin Band David C Whiteman Francesco Lescai Cordelia Langford Manoj Nanji Sarah Edkins Anouk van der Winkel David Levine Peter Sasieni Céline Bellenguez Kimberley Howarth Colin Freeman Nigel Trudgill Art T Tucker Matti Pirinen Maikel P Peppelenbosch Luc J W van der Laan Ernst J Kuipers Joost P H Drenth Wilbert H Peters John V Reynolds Dermot P Kelleher Ross McManus Heike Grabsch Hans Prenen Raf Bisschops Kausila Krishnadath Peter D Siersema Jantine W P M van Baal Mark Middleton Russell Petty Richard Gillies Nicola Burch Pradeep Bhandari Stuart Paterson Cathryn Edwards Ian Penman Kishor Vaidya Yeng Ang Iain Murray Praful Patel Weimin Ye Paul Mullins Anna H Wu Nigel C Bird Helen Dallal Nicholas J Shaheen Liam J Murray Konrad Koss Leslie Bernstein Yvonne Romero Laura J Hardie Rui Zhang Helen Winter Douglas A Corley Simon Panter Harvey A Risch Brian J Reid Ian Sargeant Marilie D Gammon Howard Smart Anjan Dhar Hugh McMurtry Haythem Ali Geoffrey Liu Alan G Casson Wong-Ho Chow Matt Rutter Ashref Tawil Danielle Morris Chuka Nwokolo Peter Isaacs Colin Rodgers Krish Ragunath Chris MacDonald Chris Haigh David Monk Gareth Davies Saj Wajed David Johnston Michael Gibbons Sue Cullen Nicholas Church Ruth Langley Michael Griffin Derek Alderson Panos Deloukas Sarah E Hunt Emma Gray Serge Dronov Simon C Potter Avazeh Tashakkori-Ghanbaria Mark Anderson Claire Brooks Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden Corvin Audrey Duncanson Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas Wood Gosia Trynka Cisca Wijmenga Jean-Baptiste Cazier Paul Atherfold Anna M Nicholson Nichola L Gellatly Deborah Glancy Sheldon C Cooper David Cunningham Tore Lind Julie Hapeshi David Ferry Barrie Rathbone Julia Brown Sharon Love Stephen Attwood Stuart MacGregor Peter Watson Scott Sanders Weronica Ek Rebecca F Harrison Paul Moayyedi John de Caestecker Hugh Barr Elia Stupka Thomas L Vaughan Leena Peltonen Chris C A Spencer Ian Tomlinson Peter Donnelly Janusz A Z Jankowski

Nat Genet 2012 Oct 9;44(10):1131-6. Epub 2012 Sep 9.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.2408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459818PMC
October 2012

Genes of the interleukin-18 pathway are associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma.

Authors:
Mahwash Babar Anthony W Ryan Lesley A Anderson Ricardo Segurado Graham Turner Liam J Murray Seamus J Murphy Brian T Johnston Harry Comber John V Reynolds Ross McManus

Am J Gastroenterol 2012 Sep 5;107(9):1331-41. Epub 2012 Jun 5.

Department of Surgery, St. James's Hospital and Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/ajg.2012.134DOI Listing
September 2012

Malignant Gastrocolic Fistula as a Late Complication of Radiation Therapy.

Authors:
Joan Costelloe Clare O'Connell Orla Mc Cormack Finbar MacCarthy Darragh F Halpenny Ramadan Shatwan Cian Muldoon Narayanasamy Ravi John V Reynolds

J Gastrointest Cancer 2012 Sep;43 Suppl 1:S269-72

Department of Surgery, St. James's Hospital, Dublin, Ireland.

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http://link.springer.com/10.1007/s12029-012-9399-9
Publisher Site
http://dx.doi.org/10.1007/s12029-012-9399-9DOI Listing
September 2012

Evolving progress in oncologic and operative outcomes for esophageal and junctional cancer: lessons from the experience of a high-volume center.

Authors:
John V Reynolds Claire L Donohoe Erin McGillycuddy Naraymasamy Ravi Dermot O'Toole Ken O'Byrne Donal Hollywood

J Thorac Cardiovasc Surg 2012 May 11;143(5):1130-1137.e1. Epub 2012 Jan 11.

Department of Surgery, St James's Hospital and Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jtcvs.2011.12.003DOI Listing
May 2012

Elevated Tumor Expression of PAI-1 and SNAI2 in Obese Esophageal Adenocarcinoma Patients and Impact on Prognosis.

Authors:
Emma H Allott Melissa J Morine Joanne Lysaght Sarah A McGarrigle Claire L Donohoe John V Reynolds Helen M Roche Graham P Pidgeon

Clin Transl Gastroenterol 2012 Apr 19;3:e12. Epub 2012 Apr 19.

Department of Surgery, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1038/ctg.2012.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365676PMC
April 2012

Radiation sensitivity of esophageal adenocarcinoma: the contribution of the RNA-binding protein RNPC1 and p21-mediated cell cycle arrest to radioresistance.

Authors:
Gijsbert J Hötte Niamh Linam-Lennon John V Reynolds Stephen G Maher

Radiat Res 2012 Mar 3;177(3):272-9. Epub 2012 Jan 3.

Department of Surgery, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1667/rr2776.1DOI Listing
March 2012

IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity.

Authors:
Suzanne L Doyle Claire L Donohoe Stephen P Finn Julia M Howard Fiona E Lithander John V Reynolds Graham P Pidgeon Joanne Lysaght

Am J Gastroenterol 2012 Feb 6;107(2):196-204. Epub 2011 Dec 6.

Department of Surgery, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital and University of Dublin, Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1038/ajg.2011.417DOI Listing
February 2012

Necrotizing pancreatitis presenting with pneumatosis coli and hepatic portal venous gas.

Authors:
James D Martin-Smith John O Larkin John G Hogan Narayanasamy Ravi John V Reynolds

ANZ J Surg 2011 Jun;81(6):467-8

Department of Clinical Surgery, St James’s Hospital and Trinity College, Dublin, Ireland.

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June 2011