John V Moran

John V Moran

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John V Moran

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Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition.

Mol Cell 2019 Sep 28;75(6):1286-1298.e12. Epub 2019 Aug 28.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754305PMC
September 2019

Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication.

Cell 2019 May 4;177(4):837-851.e28. Epub 2019 Apr 4.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, 48109, USA; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.02.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558663PMC
May 2019

Spliced integrated retrotransposed element (SpIRE) formation in the human genome.

PLoS Biol 2018 03 5;16(3):e2003067. Epub 2018 Mar 5.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.2003067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860796PMC
March 2018

Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells.

PLoS Genet 2017 Oct 13;13(10):e1007051. Epub 2017 Oct 13.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656329PMC
October 2017

Mobile DNA in Health and Disease.

N Engl J Med 2017 Jul;377(4):361-370

From the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore (H.H.K.), and the Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, Ann Arbor (J.V.M.).

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http://dx.doi.org/10.1056/NEJMra1510092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980640PMC
July 2017

LINE-1 Cultured Cell Retrotransposition Assay.

Methods Mol Biol 2016 ;1400:139-56

Department of Human Genetics, University of Michigan Medical School, 1241 E. Catherine St, Ann Arbor, MI, 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070806PMC
http://dx.doi.org/10.1007/978-1-4939-3372-3_10DOI Listing
December 2016

LEAP: L1 Element Amplification Protocol.

Methods Mol Biol 2016 ;1400:339-55

Department of Human Genetics, University of Michigan Medical School, 1241 E. Catherine Street, Ann Arbor, MI, 48109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070798PMC
http://dx.doi.org/10.1007/978-1-4939-3372-3_21DOI Listing
December 2016

p53 genes function to restrain mobile elements.

Genes Dev 2016 Jan 23;30(1):64-77. Epub 2015 Dec 23.

Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA;

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http://dx.doi.org/10.1101/gad.266098.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701979PMC
January 2016

A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition.

Mol Cell 2015 Dec 12;60(5):728-741. Epub 2015 Nov 12.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA; Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671821PMC
December 2015

The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition.

PLoS Genet 2015 May 7;11(5):e1005121. Epub 2015 May 7.

Cellular and Molecular Biology Graduate Program, University of Michigan, Ann Arbor, Michigan, United States of America; Departments of Human Genetics and Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423928PMC
May 2015

The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes.

Microbiol Spectr 2015 Apr;3(2):MDNA3-0061-2014

Department of Human Genetics; Cellular and Molecular Biology Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan 48109.

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http://dx.doi.org/10.1128/microbiolspec.MDNA3-0061-2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498412PMC
April 2015

Mobile genetic elements and genome evolution 2014.

Mob DNA 2014 18;5:26. Epub 2014 Nov 18.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD USA.

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http://dx.doi.org/10.1186/1759-8753-5-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363357PMC
November 2014

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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http://dx.doi.org/10.1126/science.1251546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138491PMC
June 2014

RNase L restricts the mobility of engineered retrotransposons in cultured human cells.

Nucleic Acids Res 2014 Apr 25;42(6):3803-20. Epub 2013 Dec 25.

Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, OH, 44195, USA, Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA, Department of Human Genetics, Ann Arbor, MI 48109, USA, Cellular and Molecular Biology Program, Ann Arbor, MI 48109, USA, Department of Internal Medicine, Ann Arbor, MI 48109, USA and Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, Michigan, 48109, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkt1308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973342PMC
April 2014

APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition.

Elife 2014 Apr 24;3:e02008. Epub 2014 Apr 24.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, United States Department of Internal Medicine, Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, United States

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003774PMC
http://dx.doi.org/10.7554/eLife.02008DOI Listing
April 2014

2013 Curt Stern Award Address.

Authors:
John V Moran

Am J Hum Genet 2014 Mar;94(3):340-8

Departments of Human Genetics and Internal Medicine, 1241 East Catherine Street, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA; Howard Hughes Medical Institute. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951928PMC
March 2014

Genomic impact of eukaryotic transposable elements.

Mob DNA 2012 Nov 21;3(1):19. Epub 2012 Nov 21.

Institute of Experimental Pathology, ZMBE, University of Münster, Münster D-48149, Germany.

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http://dx.doi.org/10.1186/1759-8753-3-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520738PMC
November 2012

Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility.

Hum Mol Genet 2012 Jan 11;21(1):208-18. Epub 2011 Oct 11.

Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/hmg/ddr455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235014PMC
January 2012

Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase.

Proc Natl Acad Sci U S A 2011 Dec 22;108(51):20345-50. Epub 2011 Sep 22.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-5618, USA.

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http://dx.doi.org/10.1073/pnas.1100275108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251045PMC
December 2011

LINE-1 elements in structural variation and disease.

Annu Rev Genomics Hum Genet 2011 ;12:187-215

Department of Human Genetics, University of MIchigan Medical School, Ann Arbor, Michigan 48109-5618, USA.

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http://www.annualreviews.org/doi/10.1146/annurev-genom-08250
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http://dx.doi.org/10.1146/annurev-genom-082509-141802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124830PMC
October 2011

Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells.

J Biol Chem 2011 Oct 30;286(42):36427-37. Epub 2011 Aug 30.

Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1074/jbc.M111.251058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196128PMC
October 2011

Dynamic interactions between transposable elements and their hosts.

Nat Rev Genet 2011 Aug 18;12(9):615-27. Epub 2011 Aug 18.

Section on Eukaryotic Transposable Elements, Laboratory of Gene Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.nature.com/articles/nrg3030
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http://dx.doi.org/10.1038/nrg3030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192332PMC
August 2011

Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.

Nature 2010 Aug;466(7307):769-73

Department of Human Genetics, 1241 East Catherine Street, University of Michigan Medical School, Ann Arbor, Michigan 48109-5618, USA.

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http://dx.doi.org/10.1038/nature09209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034402PMC
August 2010

LINE-1 retrotransposition activity in human genomes.

Cell 2010 Jun;141(7):1159-70

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.cell.2010.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013285PMC
June 2010

Diamonds and rust: how transposable elements influence mammalian genomes. Conference on Mobile Elements in Mammalian Genomes.

EMBO Rep 2009 Dec 13;10(12):1306-10. Epub 2009 Nov 13.

Howard Hughes Medical Institute, Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/embor.2009.248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799207PMC
December 2009

L1 retrotransposition in human neural progenitor cells.

Nature 2009 Aug 5;460(7259):1127-31. Epub 2009 Aug 5.

Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature08248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909034PMC
August 2009

Active Alu retrotransposons in the human genome.

Genome Res 2008 Dec 3;18(12):1875-83. Epub 2008 Oct 3.

Genetics and Molecular Biology Graduate Program, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1101/gr.081737.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593586PMC
December 2008

LINE-1 retrotransposition in human embryonic stem cells.

Hum Mol Genet 2007 Jul 27;16(13):1569-77. Epub 2007 Apr 27.

Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, 1241 E. Catherine Street, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1093/hmg/ddm105DOI Listing
July 2007

Characterization of pre-insertion loci of de novo L1 insertions.

Gene 2007 Apr 12;390(1-2):190-8. Epub 2006 Sep 12.

Tulane Cancer Center and Department of Epidemiology, Tulane University Health Sciences Center SL-66, 1430 Tulane Ave., New Orleans, LA 70112, United States.

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http://dx.doi.org/10.1016/j.gene.2006.08.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850991PMC
April 2007

Selective inhibition of Alu retrotransposition by APOBEC3G.

Gene 2007 Apr 27;390(1-2):199-205. Epub 2006 Sep 27.

Department of Human Genetics, The University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.gene.2006.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917221PMC
April 2007

Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres.

Nature 2007 Mar;446(7132):208-12

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109-0618, USA.

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http://dx.doi.org/10.1038/nature05560DOI Listing
March 2007

Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particles.

Nat Struct Mol Biol 2006 Jul 18;13(7):655-60. Epub 2006 Jun 18.

Department of Human Genetics 1241 E. Catherine St., University of Michigan Medical School, Ann Arbor, Michigan 48109-0618, USA.

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http://www.nature.com/articles/nsmb1107
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http://dx.doi.org/10.1038/nsmb1107DOI Listing
July 2006

Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.

Proc Natl Acad Sci U S A 2006 Jun 25;103(23):8780-5. Epub 2006 May 25.

Center for Virology and Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0603313103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482655PMC
June 2006

L1 retrotransposition in nondividing and primary human somatic cells.

Proc Natl Acad Sci U S A 2006 May 12;103(21):8036-41. Epub 2006 May 12.

Department of Medicine, UCLA School of Medicine, 675 Charles E. Young Drive South, MRL-1551, Los Angeles, CA 90095-7019, USA.

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http://dx.doi.org/10.1073/pnas.0601954103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472425PMC
May 2006

Unconventional translation of mammalian LINE-1 retrotransposons.

Genes Dev 2006 Jan;20(2):210-24

Department of Human Genetics and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0618, USA.

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http://dx.doi.org/10.1101/gad.1380406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356112PMC
January 2006

Ribonucleoprotein particle formation is necessary but not sufficient for LINE-1 retrotransposition.

Hum Mol Genet 2005 Nov 23;14(21):3237-48. Epub 2005 Sep 23.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109-0618, USA.

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http://dx.doi.org/10.1093/hmg/ddi354DOI Listing
November 2005

Multiple fates of L1 retrotransposition intermediates in cultured human cells.

Mol Cell Biol 2005 Sep;25(17):7780-95

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, 48109-0618, USA.

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http://dx.doi.org/10.1128/MCB.25.17.7780-7795.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190285PMC
September 2005

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition.

Nature 2005 Jun;435(7044):903-10

Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature03663DOI Listing
June 2005

Characterization of a mutagenic B1 retrotransposon insertion in the jittery mouse.

Hum Mutat 2004 Jul;24(1):9-13

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1002/humu.20060DOI Listing
July 2004

A YY1-binding site is required for accurate human LINE-1 transcription initiation.

Nucleic Acids Res 2004 22;32(13):3846-55. Epub 2004 Jul 22.

Department of Human Genetics, The University of Michigan Medical School, Ann Arbor, MI 48109-0618, USA.

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http://dx.doi.org/10.1093/nar/gkh698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC506791PMC
July 2004

Allelic heterogeneity in LINE-1 retrotransposition activity.

Am J Hum Genet 2003 Dec 7;73(6):1431-7. Epub 2003 Nov 7.

Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109-0618, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970763992
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180405PMC
http://dx.doi.org/10.1086/379744DOI Listing
December 2003

Mobile elements and mammalian genome evolution.

Curr Opin Genet Dev 2003 Dec;13(6):651-8

Department of Environmental Health Sciences, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.

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December 2003

ATLAS: a system to selectively identify human-specific L1 insertions.

Am J Hum Genet 2003 Apr 11;72(4):823-38. Epub 2003 Mar 11.

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1086/373939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180347PMC
April 2003

Hot L1s account for the bulk of retrotransposition in the human population.

Proc Natl Acad Sci U S A 2003 Apr 7;100(9):5280-5. Epub 2003 Apr 7.

Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0831042100
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http://dx.doi.org/10.1073/pnas.0831042100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC154336PMC
April 2003

Of man in mice.

Nat Genet 2002 Dec 4;32(4):562-3. Epub 2002 Nov 4.

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http://dx.doi.org/10.1038/ng1043DOI Listing
December 2002

A comprehensive analysis of recently integrated human Ta L1 elements.

Am J Hum Genet 2002 Aug 17;71(2):312-26. Epub 2002 Jun 17.

Department of Biological Sciences, Biological Computation and Visualization Center, Louisiana State University, 202 Life Sciences Building, Baton Rouge, LA 70803, USA.

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http://dx.doi.org/10.1086/341718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC379164PMC
August 2002

Genomic deletions created upon LINE-1 retrotransposition.

Cell 2002 Aug;110(3):315-25

Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/s0092-8674(02)00828-0DOI Listing
August 2002

DNA repair mediated by endonuclease-independent LINE-1 retrotransposition.

Nat Genet 2002 Jun 13;31(2):159-65. Epub 2002 May 13.

Department of Human Genetics, University of Michigan Medical School, 1241 E. Catherine Street, Ann Arbor, Michigan 48105-0618, USA.

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http://dx.doi.org/10.1038/ng898DOI Listing
June 2002