John Trowsdale

John Trowsdale

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John Trowsdale

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Genetics of antigen processing and presentation.

Immunogenetics 2019 03 13;71(3):161-170. Epub 2018 Sep 13.

Department of Pathology, University of Cambridge, Cambridge, CB21QP, UK.

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http://dx.doi.org/10.1007/s00251-018-1082-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394470PMC
March 2019

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.

J Immunol 2018 11 24;201(9):2593-2601. Epub 2018 Sep 24.

Department of Obstetrics and Gynaecology, University of Cambridge School of Clinical Medicine, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge CB2 0SW, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1800860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258046PMC
November 2018

Novel KIR genotypes and gene copy number variations in northeastern Thais.

Immunology 2018 03 23;153(3):380-386. Epub 2017 Oct 23.

The Centre for Research and Development of Medical Diagnostic Laboratories (CMDL), Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.

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http://dx.doi.org/10.1111/imm.12847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795178PMC
March 2018

Introduction: MHC/KIR and governance of specificity.

Immunogenetics 2017 08 10;69(8-9):481-488. Epub 2017 Jul 10.

Department of Pathology, University of Cambridge, Cambridge, CB21QP, UK.

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http://dx.doi.org/10.1007/s00251-017-0986-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537316PMC
August 2017

Interaction of the LILRB1 inhibitory receptor with HLA class Ia dimers.

Eur J Immunol 2016 07 2;46(7):1681-90. Epub 2016 Jun 2.

Immunology Unit, University Pompeu Fabra, Barcelona, Spain.

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http://dx.doi.org/10.1002/eji.201546149DOI Listing
July 2016

Regulation of Immunity by Butyrophilins.

Annu Rev Immunol 2016 05 11;34:151-72. Epub 2016 Jan 11.

Department of Pathology, Immunology Division, University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 0XY, United Kingdom; email: ,

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http://dx.doi.org/10.1146/annurev-immunol-041015-055435DOI Listing
May 2016

Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans.

Cell Rep 2016 05 21;15(5):1088-1099. Epub 2016 Apr 21.

Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 14186 Stockholm, Sweden; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, 75015 Paris, France; University Paris Descartes, Imagine Institute, 75270 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858565PMC
May 2016

Host response: Sensing microbial sabotage.

Authors:
John Trowsdale

Nat Microbiol 2016 05 26;1(6):16071. Epub 2016 May 26.

Pathology Department, Tennis Court Road, University of Cambridge, Cambridge CB21QP, UK.

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http://dx.doi.org/10.1038/nmicrobiol.2016.71DOI Listing
May 2016

TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils.

J Immunol 2015 Oct 26;195(7):3149-59. Epub 2015 Aug 26.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.

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http://dx.doi.org/10.4049/jimmunol.1401847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595996PMC
October 2015

Imputation of KIR Types from SNP Variation Data.

Am J Hum Genet 2015 Oct;97(4):593-607

Statistical Genetics, Murdoch Childrens Research Institute, Parkville, VIC 3052, Australia; School of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596914PMC
October 2015

Surveillance of cell and tissue perturbation by receptors in the LRC.

Immunol Rev 2015 Sep;267(1):117-36

Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/imr.12314DOI Listing
September 2015

Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.

J Immunol 2015 Mar 30;194(5):2390-8. Epub 2015 Jan 30.

Immunology Division, Department of Pathology, University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 0XY, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1401064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337483PMC
March 2015

Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR.

Genome Med 2014 5;6(3):20. Epub 2014 Mar 5.

Cambridge Institute for Medical Research, Addenbrooke's Hospital, Cambridge CB2 0XY, UK ; Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.

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http://genomemedicine.biomedcentral.com/articles/10.1186/gm5
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http://dx.doi.org/10.1186/gm537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062048PMC
August 2014

Medawar and the immunological paradox of pregnancy: 60 years on.

Eur J Immunol 2014 Jul;44(7):1883-5

University of Cambridge and Centre for Trophoblast Research, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.201470065DOI Listing
July 2014

Recognition of Salmonella by Dectin-1 induces presentation of peptide antigen to type B T cells.

Eur J Immunol 2014 Apr 16;44(4):962-9. Epub 2014 Feb 16.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.201344065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282065PMC
April 2014

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

BMC Genomics 2014 Apr 11;15:274. Epub 2014 Apr 11.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, CB2 0XY, Cambridge, UK.

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http://dx.doi.org/10.1186/1471-2164-15-274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029094PMC
April 2014

HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation.

World J Gastroenterol 2014 Apr;20(14):3986-4000

Bjarte Fosby, Sigrid Næss, Johannes R Hov, Kirsten M Boberg, Espen Melum, Tom H Karlsen, Norwegian PSC Research Center, Division of Cancer, Surgery and Transplantation, Oslo University Hospital, N-0424 Oslo, Norway.

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http://dx.doi.org/10.3748/wjg.v20.i14.3986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983454PMC
April 2014

Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors.

Immunogenetics 2014 Feb 21;66(2):73-83. Epub 2013 Nov 21.

Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.

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http://link.springer.com/10.1007/s00251-013-0742-5
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http://dx.doi.org/10.1007/s00251-013-0742-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894450PMC
February 2014

Development and use of IgM/J-chain fusion proteins for characterization of immunoglobulin superfamily ligand-receptor interactions.

Curr Protoc Protein Sci 2014 Feb 3;75:Unit 19.24.. Epub 2014 Feb 3.

Department of Pathology, Division of Immunology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1002/0471140864.ps1924s75DOI Listing
February 2014

A novel family of human leukocyte antigen class II receptors may have its origin in archaic human species.

J Biol Chem 2014 Jan 8;289(2):639-53. Epub 2013 Nov 8.

From the Section of Immunobiology, Institute of Genetics, University of Bonn, 53115 Bonn, Germany.

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http://dx.doi.org/10.1074/jbc.M113.515767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887193PMC
January 2014

Major histocompatibility complex genomics and human disease.

Annu Rev Genomics Hum Genet 2013 15;14:301-23. Epub 2013 Jul 15.

Department of Pathology and Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 1QP, United Kingdom; email:

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http://dx.doi.org/10.1146/annurev-genom-091212-153455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426292PMC
December 2013

Natural killer cells and their receptors in multiple sclerosis.

Brain 2013 Sep 25;136(Pt 9):2657-76. Epub 2012 Jun 25.

MRC Human Immunology Unit, Nuffield Department of Medicine, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DS, UK.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/aws159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754456PMC
September 2013

Ubiquitination of HLA-DO by MARCH family E3 ligases.

Eur J Immunol 2013 May 11;43(5):1153-61. Epub 2013 Mar 11.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.201243043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655539PMC
May 2013

Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes.

J Immunol 2013 May 15;190(10):5030-6. Epub 2013 Apr 15.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1203325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736090PMC
May 2013

Salmonella polarises peptide-MHC-II presentation towards an unconventional Type B CD4+ T-cell response.

Eur J Immunol 2013 Apr 18;43(4):897-906. Epub 2013 Feb 18.

Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1002/eji.201242983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816330PMC
April 2013

HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model.

J Immunol 2013 Mar 6;190(6):2880-5. Epub 2013 Feb 6.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1200650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197943PMC
March 2013

Tapasin-related protein TAPBPR is an additional component of the MHC class I presentation pathway.

Proc Natl Acad Sci U S A 2013 Feb 11;110(9):3465-70. Epub 2013 Feb 11.

Department of Pathology, Cambridge Institute of Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1222342110
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http://dx.doi.org/10.1073/pnas.1222342110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587277PMC
February 2013

Ligand specificity of Killer cell Immunoglobulin-like Receptors: a brief history of KIR.

Front Immunol 2012 24;3:394. Epub 2012 Dec 24.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center Leiden, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2012.00394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529305PMC
December 2012

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors.

Genome Res 2012 Oct 4;22(10):1845-54. Epub 2012 Sep 4.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.1101/gr.137976.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460180PMC
October 2012

Structural requirements for recognition of major histocompatibility complex class II by membrane-associated RING-CH (MARCH) protein E3 ligases.

J Biol Chem 2012 Aug 3;287(34):28779-89. Epub 2012 Jul 3.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M112.381541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436574PMC
August 2012

Characterisation of bovine leukocyte Ig-like receptors.

PLoS One 2012 2;7(4):e34291. Epub 2012 Apr 2.

Centre for Infection, Division of Clinical Sciences, St George's, University of London, Cranmer Terrace, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034291PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317502PMC
July 2012

Signatures of historical demography and pathogen richness on MHC class I genes.

Immunogenetics 2012 Mar 23;64(3):165-75. Epub 2011 Sep 23.

Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, UK.

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http://link.springer.com/10.1007/s00251-011-0576-y
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http://dx.doi.org/10.1007/s00251-011-0576-yDOI Listing
March 2012

Ubiquitination of human leukocyte antigen (HLA)-DM by different membrane-associated RING-CH (MARCH) protein family E3 ligases targets different endocytic pathways.

J Biol Chem 2012 Mar 13;287(10):7256-64. Epub 2012 Jan 13.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M111.305961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293585PMC
March 2012

Intracellular antibody-mediated immunity and the role of TRIM21.

Bioessays 2011 Nov 29;33(11):803-9. Epub 2011 Aug 29.

MRC Laboratory of Molecular Biology, PNAC Division, Cambridge, UK.

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http://dx.doi.org/10.1002/bies.201100093DOI Listing
November 2011

The MHC, disease and selection.

Authors:
John Trowsdale

Immunol Lett 2011 Jun 22;137(1-2):1-8. Epub 2011 Jan 22.

Department of Pathology, Tennis Court Road and CIMR, Addenbrookes Site, University of Cambridge, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S016524781100007
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http://dx.doi.org/10.1016/j.imlet.2011.01.002DOI Listing
June 2011

HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding.

J Immunol 2011 Mar 26;186(5):2990-7. Epub 2011 Jan 26.

Immunology Division, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1003078
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http://dx.doi.org/10.4049/jimmunol.1003078DOI Listing
March 2011

Genetic variation, Fcγ receptors, KIRs and infection: the evolution of autoimmunity.

Curr Opin Immunol 2010 Dec 1;22(6):715-22. Epub 2010 Nov 1.

Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Box 139 Addenbrooke's Hospital, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1016/j.coi.2010.10.003DOI Listing
December 2010

ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients.

Int J Cancer 2010 Sep;127(6):1412-20

Academic Division of Clinical Oncology, University of Nottingham, City Hospital Campus, Nottingham, United Kingdom.

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http://dx.doi.org/10.1002/ijc.25156DOI Listing
September 2010

Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation.

Proc Natl Acad Sci U S A 2010 Sep 30;107(37):16240-5. Epub 2010 Aug 30.

Department of Pathology, Immunology Division, University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1003421107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941293PMC
September 2010

Intracellular sequestration of the NKG2D ligand ULBP3 by human cytomegalovirus.

J Immunol 2010 Jul 7;185(2):1093-102. Epub 2010 Jun 7.

Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1000789DOI Listing
July 2010

Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform.

J Biol Chem 2010 May 19;285(22):16408-15. Epub 2010 Mar 19.

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge CB2 0XY, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.077636
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http://dx.doi.org/10.1074/jbc.M109.077636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878053PMC
May 2010

BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation.

J Immunol 2010 Apr 5;184(7):3514-25. Epub 2010 Mar 5.

Immunology Division, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.0900416DOI Listing
April 2010

Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex.

Hum Mol Genet 2010 Mar 3;19(5):737-51. Epub 2009 Dec 3.

Division of Immunology, Department of Pathology, University of Cambridge Cambridge CB2 1QP, UK.

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http://dx.doi.org/10.1093/hmg/ddp538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816608PMC
March 2010

NKG2D ligand MICA is retained in the cis-Golgi apparatus by human cytomegalovirus protein UL142.

J Virol 2009 Dec 30;83(23):12345-54. Epub 2009 Sep 30.

Department of Pathology, Cambridge Institute for Medical Research, University of Cambridge,Cambridge, United Kingdom.

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http://dx.doi.org/10.1128/JVI.01175-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786768PMC
December 2009

Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes.

Eur J Immunol 2009 Nov;39(11):3195-206

Division of Immunology, Department of Pathology, University of Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200839080DOI Listing
November 2009

ULBP6/RAET1L is an additional human NKG2D ligand.

Eur J Immunol 2009 Nov;39(11):3207-16

Cambridge Institute for Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200939502DOI Listing
November 2009

NKG2D ligand expression in human colorectal cancer reveals associations with prognosis and evidence for immunoediting.

Clin Cancer Res 2009 Nov 27;15(22):6993-7002. Epub 2009 Oct 27.

Academic Division of Clinical Oncology, University of Nottingham, City Hospital Campus, Section of Gastrointestinal Surgery, Queen's Medical Centre, John Van Geest Research Centre, Nottingham Trent University, Clifton Campus, Nottingham, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778653PMC
November 2009

Salmonella regulates polyubiquitination and surface expression of MHC class II antigens.

Proc Natl Acad Sci U S A 2009 Aug 5;106(33):14052-7. Epub 2009 Aug 5.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0906735106
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http://dx.doi.org/10.1073/pnas.0906735106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721820PMC
August 2009

Comparative genomics indicates the mammalian CD33rSiglec locus evolved by an ancient large-scale inverse duplication and suggests all Siglecs share a common ancestral region.

Immunogenetics 2009 May 1;61(5):401-17. Epub 2009 Apr 1.

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building Addenbrooke's Hospital, Cambridge, UK.

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http://link.springer.com/10.1007/s00251-009-0372-0
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http://dx.doi.org/10.1007/s00251-009-0372-0DOI Listing
May 2009

The HLA-DRalpha chain is modified by polyubiquitination.

J Biol Chem 2009 Mar 31;284(11):7007-16. Epub 2008 Dec 31.

Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M805736200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652342PMC
March 2009

Cutting edge: killer Ig-like receptors mediate "missing self" recognition in vivo.

J Immunol 2009 Mar;182(5):2569-72

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.0804042DOI Listing
March 2009

NK receptor interactions with MHC class I molecules in pregnancy.

Semin Immunol 2008 Dec 24;20(6):317-20. Epub 2008 Jul 24.

Immunology Division, Department of Pathology, Tennis Court Road, Cambridge CB2 1QP, United Kingdom.

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http://dx.doi.org/10.1016/j.smim.2008.06.002DOI Listing
December 2008

SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.

Eur J Immunol 2008 Aug;38(8):2303-15

Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200738078DOI Listing
August 2008

The extended human leukocyte receptor complex: diverse ways of modulating immune responses.

Immunol Rev 2008 Aug;224:98-123

Immunology Division, Cambridge Institute for Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1600-065X.2008.00653.xDOI Listing
August 2008

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. 1990.

J Immunol 2008 Mar;180(5):2733-6

Imperial Cancer Research Fund, Lincolns Inn Fields, London, UK.

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March 2008

Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects its cellular localisation and transport.

J Neurochem 2007 Sep 15;102(6):1853-1862. Epub 2007 Jun 15.

Department of Pathology, Cambridge Institute of Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04687.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156149PMC
September 2007

Promiscuity and the single receptor: NKG2D.

Nat Rev Immunol 2007 Sep 3;7(9):737-44. Epub 2007 Aug 3.

Robert A. Eagle and John Trowsdale are at the University of Cambridge Department of Pathology, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrookes Hospital, Hills Road, Cambridge CB2 OXY, UK.

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http://dx.doi.org/10.1038/nri2144DOI Listing
September 2007

The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN.

J Immunol 2007 Sep;179(6):3804-11

Department of Pathology, Division of Immunology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.179.6.3804DOI Listing
September 2007

Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.

Blood 2007 May 11;109(9):3776-85. Epub 2007 Jan 11.

Division of Cell and Molecular Biology, Imperial College London, South Kensington Campus, London, UK.

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http://dx.doi.org/10.1182/blood-2006-10-052977DOI Listing
May 2007

Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function.

Proc Natl Acad Sci U S A 2007 Apr 30;104(15):6200-5. Epub 2007 Mar 30.

Protein and Nucleic Acid Chemistry Division, Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH, UK.

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http://dx.doi.org/10.1073/pnas.0609174104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851072PMC
April 2007

TRIM21 is a trimeric protein that binds IgG Fc via the B30.2 domain.

Mol Immunol 2007 Mar 21;44(9):2406-14. Epub 2006 Nov 21.

Department of Pathology, Immunology Division, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1016/j.molimm.2006.10.013DOI Listing
March 2007

Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies.

Eur J Immunol 2007 Mar;37(3):780-7

Department of Pathology, Cambridge University, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200636773DOI Listing
March 2007

Multiple sclerosis: putting two and two together.

Authors:
John Trowsdale

Nat Med 2006 Oct;12(10):1119-21

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http://dx.doi.org/10.1038/nm1006-1119DOI Listing
October 2006

Nature of allelic sequence polymorphism at the KIR3DL3 locus.

Immunogenetics 2006 Aug 6;58(8):614-27. Epub 2006 Jul 6.

Division of Immunology, Department of Pathology,, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.

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http://dx.doi.org/10.1007/s00251-006-0130-5DOI Listing
August 2006

You say ITAM and I say ITIM, let's call the whole thing off: the ambiguity of immunoreceptor signalling.

Eur J Immunol 2006 Jul;36(7):1646-53

Cambridge Institute for Medical Research, Wellcome Trust/Medical Research Council building, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.200636195DOI Listing
July 2006