Publications by authors named "John Tam"

132 Publications

Influenza and COVID-19: What does co-existence mean?

Influenza Other Respir Viruses 2020 Oct 31. Epub 2020 Oct 31.

The Hong Kong Polytechnic University, Hung Hom, Hong Kong.

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October 2020

Organization of thoracic surgical services during the COVID pandemic.

Surgeon 2021 Feb 7;19(1):e1-e8. Epub 2020 Aug 7.

Department of Cardiac, Thoracic and Vascular Surgery, National University Heart Centre Singapore, National University Hospital Singapore, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. Electronic address:

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February 2021

Eomes Expression Defines Group 1 Innate Lymphoid Cells During Metastasis in Human and Mouse.

Front Immunol 2020 17;11:1190. Epub 2020 Jun 17.

Department of Biological Sciences, National University of Singapore, Singapore, Singapore.

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June 2020

Reply to "Health literacy, a crucial determinant of vaccination decision-making among pregnant women" by Castro-Sánchez et al.

Int J Infect Dis 2020 08 20;97:380-381. Epub 2020 Jun 20.

Chairman of the Asia Pacific Alliance for the control of influenza (APACI); Adjunct Professor, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong.

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August 2020

Postoperative Psychological Disorders Among Heart Transplant Recipients: A Meta-Analysis and Meta-Regression.

Psychosom Med 2020 09;82(7):689-698

From the Departments of Psychological Medicine (Loh, Ho) and Surgery (Tam), Yong Loo Lin School of Medicine (Tan), National University of Singapore; Department of Cardiac, Thoracic and Vascular Surgery (Tam), National University Heart Centre; Institute of Mental Health, National Health Group (Zhang); Department of Psychological Medicine (Ho), National University Health System; and Biomedical Institute for Global Health Research and Technology (Ho), National University of Singapore, Singapore, Singapore.

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September 2020

pHLuc, a Ratiometric Luminescent Reporter for Monitoring of Tumor Acidosis.

Front Bioeng Biotechnol 2020 8;8:412. Epub 2020 May 8.

Department of Biological Sciences, National University of Singapore, Singapore, Singapore.

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May 2020

Intestinal bile acids directly modulate the structure and function of TcdB toxin.

Proc Natl Acad Sci U S A 2020 03 9;117(12):6792-6800. Epub 2020 Mar 9.

Molecular Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada;

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March 2020

Vaccinating pregnant women against influenza needs to be a priority for all countries: An expert commentary.

Int J Infect Dis 2020 Mar 19;92:1-12. Epub 2019 Dec 19.

Chairman of the Asia Pacific Alliance for the control of influenza (APACI); Adjunct Professor, Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong.

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March 2020

Video-Assisted Thoracic Surgery (VATS) Talc Pleurodesis Versus Pleurectomy for Primary Spontaneous Pneumothorax: A Large Single-Centre Study with No Conversion.

World J Surg 2019 08;43(8):2099-2105

Department of Cardiac, Thoracic and Vascular Surgery, National University Heart Centre Singapore, National University Health System, Singapore, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore, 119228, Singapore.

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August 2019

Novel AU-rich proximal UTR sequences (APS) enhance CXCL8 synthesis upon the induction of rpS6 phosphorylation.

PLoS Genet 2019 04 10;15(4):e1008077. Epub 2019 Apr 10.

Department of Biological Sciences, National University of Singapore, Singapore.

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April 2019

Host-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiota.

Nat Commun 2018 12 7;9(1):5233. Epub 2018 Dec 7.

Molecular Medicine, Hospital for Sick Children, 686 Bay St., Toronto, ON, M5G 0A4, Canada.

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December 2018

Comment on "A small-molecule antivirulence agent for treating Clostridium difficile infection".

Sci Transl Med 2016 12;8(370):370tc2

Molecular Structure & Function, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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December 2016

Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms.

Sci Adv 2016 05 20;2(5):e1501632. Epub 2016 May 20.

Program in Molecular Structure & Function, Research Institute, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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May 2016

The Impact of Education Reform: An Asian Medical School's Experience.

Ann Acad Med Singap 2016 May;45(5):198-204

Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore.

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May 2016

The effectiveness of a shared conference experience in improving undergraduate medical and nursing students' attitudes towards inter-professional education in an Asian country: a before and after study.

BMC Med Educ 2015 Dec 23;15:233. Epub 2015 Dec 23.

Saw Swee Hock School of Public Health and Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore, Singapore.

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December 2015

Small Molecules Take A Big Step Against Clostridium difficile.

Trends Microbiol 2015 Dec 5;23(12):746-748. Epub 2015 Nov 5.

Molecular Structure & Function, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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December 2015

Latent Mycobacterium tuberculosis Infection.

Authors:
John K C Tam

N Engl J Med 2015 09;373(12):1178-9

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September 2015

Uncovering what lies beneath a Salmonella enterica empyema.

BMJ Case Rep 2015 Sep 2;2015. Epub 2015 Sep 2.

National University Health Services, Singapore, Singapore.

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September 2015

Are medical students' views of an ideal physician eroding? A study on perceived qualities of a "role model" doctor before and after housemanship and between two cohorts five years apart.

Ann Acad Med Singap 2015 Mar;44(3):79-84

Saw Swee Hock School of Public Health, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore.

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March 2015

Small molecule inhibitors of Clostridium difficile toxin B-induced cellular damage.

Chem Biol 2015 Feb 22;22(2):175-85. Epub 2015 Jan 22.

Molecular Structure & Function, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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February 2015