John T Poirier

John T Poirier

UNVERIFIED PROFILE

Are you John T Poirier?   Register this Author

Register author
John T Poirier

John T Poirier

Publications by authors named "John T Poirier"

Are you John T Poirier?   Register this Author

42Publications

1849Reads

37Profile Views

Positron-Emission Tomographic Imaging of a Fluorine 18-Radiolabeled Poly(ADP-Ribose) Polymerase 1 Inhibitor Monitors the Therapeutic Efficacy of Talazoparib in SCLC Patient-Derived Xenografts.

J Thorac Oncol 2019 Oct 11;14(10):1743-1752. Epub 2019 Jun 11.

Molecular Pharmacology Program and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Medicine, Weill Cornell Medical College, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2019.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764879PMC
October 2019

Integrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids.

Cancer Res 2019 Sep 12;79(17):4339-4347. Epub 2019 Jul 12.

Rutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-19-0214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733269PMC
September 2019

Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers.

J Thorac Oncol 2019 May 1;14(5):802-815. Epub 2019 Mar 1.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2018.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486868PMC
May 2019

A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals.

Nucl Med Biol 2019 Apr 3;71:32-38. Epub 2019 May 3.

Department of Radiology, Memorial Sloan Kettering Cancer Center, NY, USA; Radiochemistry and Molecular Imaging Probes Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nucmedbio.2019.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599726PMC
April 2019

ProteomeGenerator: A Framework for Comprehensive Proteomics Based on de Novo Transcriptome Assembly and High-Accuracy Peptide Mass Spectral Matching.

J Proteome Res 2018 11 19;17(11):3681-3692. Epub 2018 Oct 19.

Molecular Pharmacology Program , Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center , New York City , New York 10065 , United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00295
Publisher Site
http://dx.doi.org/10.1021/acs.jproteome.8b00295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727203PMC
November 2018

Talazoparib Is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts.

Clin Cancer Res 2018 10 26;24(20):5143-5152. Epub 2018 Jun 26.

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.

View Article

Download full-text PDF

Source
http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-18-0401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742772PMC
October 2018

CRISPR Libraries and Screening.

Authors:
John T Poirier

Prog Mol Biol Transl Sci 2017 6;152:69-82. Epub 2017 Nov 6.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.pmbts.2017.10.002DOI Listing
July 2018

Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

Cancer Res 2018 04 23;78(7):1820-1832. Epub 2018 Jan 23.

Departments of Radiology and the Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-17-1958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882577PMC
April 2018

Unravelling the biology of SCLC: implications for therapy.

Nat Rev Clin Oncol 2017 Sep 23;14(9):549-561. Epub 2017 May 23.

Department of Medicine, Memorial Sloan Kettering Cancer Center.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2017.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843484PMC
September 2017

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses Loss-Driven Tumorigenesis.

Mol Cancer Ther 2017 08 3;16(8):1693-1704. Epub 2017 May 3.

Department of Cancer Biology and David H. Koch Center for Applied Research of Genitourinary Cancers, University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-16-0821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929164PMC
August 2017

Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.

J Clin Invest 2017 Aug 26;127(8):2957-2967. Epub 2017 Jun 26.

Molecular Pharmacology Program and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI93472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531414PMC
August 2017

Histone Code Aberrancies in Small Cell Lung Cancer.

J Thorac Oncol 2017 04;12(4):599-601

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2017.02.008DOI Listing
April 2017

Small-cell lung cancer in 2016: Shining light on novel targets and therapies.

Nat Rev Clin Oncol 2017 Feb 13;14(2):75-76. Epub 2016 Dec 13.

Molecular Pharmacology Program and Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA; and at the Weill Cornell Medical College, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2016.203DOI Listing
February 2017

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

Cancer Cell 2017 02;31(2):286-299

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313262PMC
February 2017

Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens.

FEBS J 2016 09 16;283(17):3170-80. Epub 2016 Jun 16.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/febs.13770DOI Listing
September 2016

Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts.

J Nucl Med 2016 06 23;57(6):981-8. Epub 2016 Feb 23.

Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.115.167932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261856PMC
June 2016

P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.

Sci Transl Med 2016 06;8(345):345ra87

Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Weill Cornell Medical College, New York, NY 10065, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064151PMC
http://dx.doi.org/10.1126/scitranslmed.aaf7374DOI Listing
June 2016

Seneca Valley Virus 3Cpro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy.

PLoS One 2015 12;10(6):e0129103. Epub 2015 Jun 12.

Department of Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129103PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466507PMC
April 2016

Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group.

Pediatr Blood Cancer 2015 May 12;62(5):743-50. Epub 2014 Oct 12.

Department of Pediatrics, Division of Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, Wisconsin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.25269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376652PMC
May 2015

Rapamycin rescues ABT-737 efficacy in small cell lung cancer.

Cancer Res 2014 May 10;74(10):2846-56. Epub 2014 Mar 10.

Authors' Affiliations: Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine; Departments of Oncology and Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/content/early/2014/03/12/0
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-13-3460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510983PMC
May 2014

Characterization of a full-length infectious cDNA clone and a GFP reporter derivative of the oncolytic picornavirus SVV-001.

J Gen Virol 2012 Dec 12;93(Pt 12):2606-13. Epub 2012 Sep 12.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/vir.0.046011-0DOI Listing
December 2012

Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer.

Mol Cancer Ther 2007 Aug;6(8):2188-97

Department of Pharmacology, CWRU School of Medicine, 10900 Euclid Avenue, Cleveland, OH 44106-4965, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-07-0235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562754PMC
August 2007