John S Witte

John S Witte

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John S Witte

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A genome-wide association study of prostate cancer in Latinos.

Int J Cancer 2019 Jun 21. Epub 2019 Jun 21.

Department of Preventative Medicine, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA.

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http://dx.doi.org/10.1002/ijc.32525DOI Listing
June 2019

Personalized Prostate Cancer Screening Based on a Single Midlife Prostate-specific Antigen Measurement.

Eur Urol 2019 03 27;75(3):408-409. Epub 2018 Sep 27.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA; Department of Urology, University of California, San Francisco, San Francisco, CA, USA; Helen Diller Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.eururo.2018.09.019DOI Listing
March 2019

Newborn Metabolic Profile Associated with Hyperbilirubinemia With and Without Kernicterus.

Clin Transl Sci 2019 Jan 28;12(1):28-38. Epub 2018 Oct 28.

Department of Epidemiology and Biostatistics and the California Preterm Birth Initiative, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1111/cts.12590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342241PMC
January 2019

Samasy: an automated system for sample selection and robotic transfer.

Biotechniques 2018 12;65(6):357-360

Department of Epidemiology & Biostatistics, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.2144/btn-2018-0090DOI Listing
December 2018

Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk.

Cancer Epidemiol Biomarkers Prev 2018 10 23;27(10):1151-1158. Epub 2018 Jul 23.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170682PMC
October 2018

Detecting Rare Mutations with Heterogeneous Effects Using a Family-Based Genetic Random Field Method.

Genetics 2018 10 13;210(2):463-476. Epub 2018 Aug 13.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan 48824

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http://dx.doi.org/10.1534/genetics.118.301266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216585PMC
October 2018

Orchid: a novel management, annotation and machine learning framework for analyzing cancer mutations.

Bioinformatics 2018 03;34(6):936-942

Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860353PMC
March 2018

An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations.

PLoS Genet 2018 02 12;14(2):e1007139. Epub 2018 Feb 12.

Department of Epidemiology and Biostatistics, University of California, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825176PMC
February 2018

Identification of Pleiotropic Cancer Susceptibility Variants from Genome-Wide Association Studies Reveals Functional Characteristics.

Cancer Epidemiol Biomarkers Prev 2018 01 17;27(1):75-85. Epub 2017 Nov 17.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760292PMC
January 2018

Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma.

J Neurooncol 2017 Nov 18;135(2):237-244. Epub 2017 Jul 18.

Division of Neuroepidemiology, Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1007/s11060-017-2569-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665694PMC
November 2017

Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology.

PLoS Genet 2017 09 28;13(9):e1006945. Epub 2017 Sep 28.

Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619686PMC
September 2017

Familial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer.

Clin Gastroenterol Hepatol 2017 Aug 24;15(8):1256-1264. Epub 2017 Jan 24.

Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Denmark; The Danish Twin Registry, University of Southern Denmark, Denmark.

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http://dx.doi.org/10.1016/j.cgh.2016.12.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522647PMC
August 2017

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

J Natl Cancer Inst 2017 08;109(8)

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1093/jnci/djx084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448553PMC
August 2017

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes.

Circ Cardiovasc Genet 2017 Apr;10(2)

From the Department of Medicine (J.D.M., M.B.S., Q.S.W., C.M.S., J.C.D., D.M.R.), Vanderbilt Epidemiology Center (T.L.E.), Department of Biomedical Informatics (L.B., J.C.D., D.M.R.), Department of Pharmacology (D.M.R.), Vanderbilt University, Nashville, TN; Division of Cardiology, University of Illinois at Chicago (D.D.); Essentia Institute of Rural Health, Duluth, MN (C.A.M.); Center for Biomedical Research Informatics, NorthShore University Health System, Evanston, IL (W.T.); School of Medicine (C.G.C.), School of Public Health (C.G.C.), and School of Nursing (C.G.C.), Johns Hopkins University, Baltimore, MD; Division of Medical Genetics, Department of Medicine (G.P.J.), Department of Genome Sciences (G.P.J.), Department of Biomedical Informatics (D.R.C.), Department of Medical Education (D.R.C.), University of Washington; Group Health Research Institute, Seattle, WA (E.B.L.); Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (I.J.K.); Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.A.P.); Biomedical Informatics Research Center (P.L.P.), Center for Human Genetics (M.H.B., J.G.L.), Marshfield Clinic Research Foundation, WI; and Department of Epidemiology and Biostatistics, University of California, San Francisco (J.S.W.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434456PMC
April 2017

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

Authors:
Maggie C Y Ng Mariaelisa Graff Yingchang Lu Anne E Justice Poorva Mudgal Ching-Ti Liu Kristin Young Lisa R Yanek Mary F Feitosa Mary K Wojczynski Kristin Rand Jennifer A Brody Brian E Cade Latchezar Dimitrov Qing Duan Xiuqing Guo Leslie A Lange Michael A Nalls Hayrettin Okut Salman M Tajuddin Bamidele O Tayo Sailaja Vedantam Jonathan P Bradfield Guanjie Chen Wei-Min Chen Alessandra Chesi Marguerite R Irvin Badri Padhukasahasram Jennifer A Smith Wei Zheng Matthew A Allison Christine B Ambrosone Elisa V Bandera Traci M Bartz Sonja I Berndt Leslie Bernstein William J Blot Erwin P Bottinger John Carpten Stephen J Chanock Yii-Der Ida Chen David V Conti Richard S Cooper Myriam Fornage Barry I Freedman Melissa Garcia Phyllis J Goodman Yu-Han H Hsu Jennifer Hu Chad D Huff Sue A Ingles Esther M John Rick Kittles Eric Klein Jin Li Barbara McKnight Uma Nayak Barbara Nemesure Adesola Ogunniyi Andrew Olshan Michael F Press Rebecca Rohde Benjamin A Rybicki Babatunde Salako Maureen Sanderson Yaming Shao David S Siscovick Janet L Stanford Victoria L Stevens Alex Stram Sara S Strom Dhananjay Vaidya John S Witte Jie Yao Xiaofeng Zhu Regina G Ziegler Alan B Zonderman Adebowale Adeyemo Stefan Ambs Mary Cushman Jessica D Faul Hakon Hakonarson Albert M Levin Katherine L Nathanson Erin B Ware David R Weir Wei Zhao Degui Zhi Donna K Arnett Struan F A Grant Sharon L R Kardia Olufunmilayo I Oloapde D C Rao Charles N Rotimi Michele M Sale L Keoki Williams Babette S Zemel Diane M Becker Ingrid B Borecki Michele K Evans Tamara B Harris Joel N Hirschhorn Yun Li Sanjay R Patel Bruce M Psaty Jerome I Rotter James G Wilson Donald W Bowden L Adrienne Cupples Christopher A Haiman Ruth J F Loos Kari E North

PLoS Genet 2017 Apr 21;13(4):e1006719. Epub 2017 Apr 21.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419579PMC
April 2017

Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk.

PLoS Genet 2017 Mar 31;13(3):e1006690. Epub 2017 Mar 31.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391966PMC
March 2017

Telomere structure and maintenance gene variants and risk of five cancer types.

Int J Cancer 2016 Dec 8;139(12):2655-2670. Epub 2016 Sep 8.

Department of Epidemiology, Geisel School of Medicine at Dartmouth, Lebanon, NH.

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http://dx.doi.org/10.1002/ijc.30288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198774PMC
December 2016

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.

Authors:
Kristin A Rand Chi Song Eric Dean Daniel J Serie Karen Curtin Xin Sheng Donglei Hu Carol Ann Huff Leon Bernal-Mizrachi Michael H Tomasson Sikander Ailawadhi Seema Singhal Karen Pawlish Edward S Peters Cathryn H Bock Alex Stram David J Van Den Berg Christopher K Edlund David V Conti Todd Zimmerman Amie E Hwang Scott Huntsman John Graff Ajay Nooka Yinfei Kong Silvana L Pregja Sonja I Berndt William J Blot John Carpten Graham Casey Lisa Chu W Ryan Diver Victoria L Stevens Michael R Lieber Phyllis J Goodman Anselm J M Hennis Ann W Hsing Jayesh Mehta Rick A Kittles Suzanne Kolb Eric A Klein Cristina Leske Adam B Murphy Barbara Nemesure Christine Neslund-Dudas Sara S Strom Ravi Vij Benjamin A Rybicki Janet L Stanford Lisa B Signorello John S Witte Christine B Ambrosone Parveen Bhatti Esther M John Leslie Bernstein Wei Zheng Andrew F Olshan Jennifer J Hu Regina G Ziegler Sarah J Nyante Elisa V Bandera Brenda M Birmann Sue A Ingles Michael F Press Djordje Atanackovic Martha J Glenn Lisa A Cannon-Albright Brandt Jones Guido Tricot Thomas G Martin Shaji K Kumar Jeffrey L Wolf Sandra L Deming Halverson Nathaniel Rothman Angela R Brooks-Wilson S Vincent Rajkumar Laurence N Kolonel Stephen J Chanock Susan L Slager Richard K Severson Nalini Janakiraman Howard R Terebelo Elizabeth E Brown Anneclaire J De Roos Ann F Mohrbacher Graham A Colditz Graham G Giles John J Spinelli Brian C Chiu Nikhil C Munshi Kenneth C Anderson Joan Levy Jeffrey A Zonder Robert Z Orlowski Sagar Lonial Nicola J Camp Celine M Vachon Elad Ziv Daniel O Stram Dennis J Hazelett Christopher A Haiman Wendy Cozen

Cancer Epidemiol Biomarkers Prev 2016 12 1;25(12):1609-1618. Epub 2016 Sep 1.

Keck School of Medicine of USC and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-1193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524541PMC
December 2016

Sequence variation in folate pathway genes and risks of human cleft lip with or without cleft palate.

Am J Med Genet A 2016 11 8;170(11):2777-2787. Epub 2016 Sep 8.

Department of Pediatrics, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1002/ajmg.a.37874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634616PMC
November 2016

Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk.

Birth Defects Res A Clin Mol Teratol 2016 Aug 21;106(8):653-8. Epub 2016 Apr 21.

Department of Pediatrics, Division of Neonatology and Developmental Medicine, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1002/bdra.23508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983249PMC
August 2016

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24.

J Natl Cancer Inst 2016 Jul 27;108(7). Epub 2016 Jan 27.

Affiliations of authors: Department of Preventive Medicine (YH, KAR, DJH, SAI, FRS, GC, LCP, XS, GAC, DOS, DVC, BEH, CAH) and Department of Urology (GAC), Keck School of Medicine, and Norris Comprehensive Cancer Center (SAI, FRS, GC, GAC, DOS, DVC, BEH, CAH), University of Southern California , Los Angeles, CA ; University of Arizona College of Medicine and University of Arizona Cancer Center , Tucson, AZ (RAK); Department of Epidemiology (SSS) and Department of Urology (CAP), University of Texas M. D. Anderson Cancer Center , Houston, TX ; Department of Public Health Sciences (BAR) and Department of Public Health Sciences (CND), Henry Ford Hospital , Detroit, MI ; Department of Preventive Medicine, Stony Brook University , Stony Brook, NY (BN, MCL, SYW, AJMH); James Buchanan Brady Urological Institute, Johns Hopkins Hospital and Medical Institution , Baltimore, MD (WBI); Division of Public Health Sciences (JLS, SK) and SWOG Statistical Center (PJG), Fred Hutchinson Cancer Research Center , Seattle, WA ; Department of Epidemiology, School of Public Health, University of Washington , Seattle, WA (JLS); Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine , Nashville, TN (WZ, WJB); Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , Bethesda, MD (SIB, ZW, MBC, SJC); Cancer Genomics Research Laboratory, NCI-DCEG, SAIC-Frederick Inc. , Frederick, MD (ZW); Program for Personalized Cancer Care and Department of Surgery, NorthShore University HealthSystem , Evanston, IL (JX); Department of Genetics (NR, DR, AT, AA, DQ, SM) and Howard Hughes Medical Institute (DR, SM), Harvard Medical School, Harvard University , Boston, MA ; Broad Institute of MIT and Harvard , Cambridge, MA (NR, DR, AT, AA, DQ, SM); Department of Pathology and Laboratory Medicine and Department of Human Genetics, David Geffen School of Medicine, University of California , Los Angeles, Los Angeles, CA (BP); Howard Hughes Medical Institute, Department of Medicine, School of Medicine, University of California , San Diego, San Diego, CA (DN, MGR, RSJ); Epidemiology Research Program, American Cancer Society , Atlanta, GA (SMG, VLS); Korle Bu Teaching Hospital , Accra , Ghana (EDY, YT, RBB, AAA, ET); University of Ghana Medical School , Accra , Ghana (EDY, YT, RBB, AAA, ET); Westat , Rockville, MD (AT, SN); School of Public Health, University of California , Berkeley, Berkeley, CA (APC); Cancer Prevention Institute of California , Fremont, CA (EMJ, AWH, LC); Stanford University School of Medicine and Stanford Cancer Institute , Palo Alto, CA (EMJ, AWH, LC); Department of Urology, Northwestern University , Chicago, IL (ABM); Department of Epidemiology, Harvard School of Public Health , Boston, MA (LBS, WJB); The Translational Genomics Research Institute , Phoenix, AZ (JC); Chronic Disease Research Centre and Faculty of Medical Sciences, University of the West Indies , Bridgetown, Barbados (AJMH); Glickman Urological & Kidney Institute, Cleveland Clinic , Cleveland, OH (EAK); Center for Cancer Genomics, Wake Forest School of Medicine , Winston-Salem, NC (SLZ); Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California , San Francisco, San Francisco, CA (JSW); School of Public Health, Makerere University College of Health Sciences , Kampala, Uganda (AL, SW); Uro Care , Kampala , Uganda (SW).

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http://dx.doi.org/10.1093/jnci/djv431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948565PMC
July 2016

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans.

AIDS 2016 07;30(11):1807-15

aDepartment of Medicine bDepartment of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California cDepartment of Medicine, Vanderbilt University School of Medicine dDepartment of Medicine, Meharry Medical College, Nashville, Tennessee, USA eDepartment of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland fRIKEN Center for Genomic Medicine, Kanagawa, Japan gDepartment of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

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http://pdfs.journals.lww.com/aidsonline/2016/07170/Host_gene
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http://dx.doi.org/10.1097/QAD.0000000000001124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925250PMC
July 2016

Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants.

Genome Res 2016 07 18;26(7):863-73. Epub 2016 May 18.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94143, USA; Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143, USA; Institute for Quantitative Biosciences (QB3), University of California, San Francisco, San Francisco, California 94143, USA;

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http://dx.doi.org/10.1101/gr.202440.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937562PMC
July 2016

Determining Which Phenotypes Underlie a Pleiotropic Signal.

Genet Epidemiol 2016 07 30;40(5):366-81. Epub 2016 May 30.

Department of Epidemiology and Biostatistics, University of California, San Francisco, United States of America.

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http://dx.doi.org/10.1002/gepi.21973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929010PMC
July 2016

Testing Allele Transmission of an SNP Set Using a Family-Based Generalized Genetic Random Field Method.

Genet Epidemiol 2016 May 7;40(4):341-51. Epub 2016 Apr 7.

Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061344PMC
http://dx.doi.org/10.1002/gepi.21970DOI Listing
May 2016

Mutational Landscape of Aggressive Prostate Tumors in African American Men.

Cancer Res 2016 04 26;76(7):1860-8. Epub 2016 Feb 26.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California. Department of Urology, University of California San Francisco, San Francisco, California. Institute for Human Genetics, University of California San Francisco, San Francisco, California. Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.

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http://cancerres.aacrjournals.org/content/early/2016/02/26/0
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http://cancerres.aacrjournals.org/content/76/7/1860.full.pdf
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http://cancerres.aacrjournals.org/content/early/2016/02/26/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-15-1787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772140PMC
April 2016

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.

Authors:
Alexander Gusev Huwenbo Shi Gleb Kichaev Mark Pomerantz Fugen Li Henry W Long Sue A Ingles Rick A Kittles Sara S Strom Benjamin A Rybicki Barbara Nemesure William B Isaacs Wei Zheng Curtis A Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Esther M John Adam B Murphy Lisa B Signorello John Carpten M Cristina Leske Suh-Yuh Wu Anslem J M Hennis Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein John S Witte Graham Casey Sam Kaggwa Michael B Cook Daniel O Stram William J Blot Rosalind A Eeles Douglas Easton Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Kenneth Muir Graham G Giles Melissa C Southey Liesel M Fitzgerald Henrik Gronberg Fredrik Wiklund Markus Aly Brian E Henderson Johanna Schleutker Tiina Wahlfors Teuvo L J Tammela Børge G Nordestgaard Tim J Key Ruth C Travis David E Neal Jenny L Donovan Freddie C Hamdy Paul Pharoah Nora Pashayan Kay-Tee Khaw Janet L Stanford Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Christiane Maier Walther Vogel Manuel Luedeke Kathleen Herkommer Adam S Kibel Cezary Cybulski Dominika Wokolorczyk Wojciech Kluzniak Lisa Cannon-Albright Craig Teerlink Hermann Brenner Aida K Dieffenbach Volker Arndt Jong Y Park Thomas A Sellers Hui-Yi Lin Chavdar Slavov Radka Kaneva Vanio Mitev Jyotsna Batra Amanda Spurdle Judith A Clements Manuel R Teixeira Hardev Pandha Agnieszka Michael Paula Paulo Sofia Maia Andrzej Kierzek David V Conti Demetrius Albanes Christine Berg Sonja I Berndt Daniele Campa E David Crawford W Ryan Diver Susan M Gapstur J Michael Gaziano Edward Giovannucci Robert Hoover David J Hunter Mattias Johansson Peter Kraft Loic Le Marchand Sara Lindström Carmen Navarro Kim Overvad Elio Riboli Afshan Siddiq Victoria L Stevens Dimitrios Trichopoulos Paolo Vineis Meredith Yeager Gosia Trynka Soumya Raychaudhuri Frederick R Schumacher Alkes L Price Matthew L Freedman Christopher A Haiman Bogdan Pasaniuc

Nat Commun 2016 Apr 7;7:10979. Epub 2016 Apr 7.

Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/ncomms10979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829663PMC
April 2016

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

Cancer Epidemiol Biomarkers Prev 2016 Jan 4;25(1):193-200. Epub 2015 Dec 4.

Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina. Cancer Prevention, Detection, and Control Research Program, Duke Cancer Institute, Durham, North Carolina. Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia.

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http://cebp.aacrjournals.org/content/25/1/193.full.pdf
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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
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http://dx.doi.org/10.1158/1055-9965.EPI-15-0649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713268PMC
January 2016

Semiparametric Allelic Tests for Mapping Multiple Phenotypes: Binomial Regression and Mahalanobis Distance.

Genet Epidemiol 2015 Dec 23;39(8):635-50. Epub 2015 Oct 23.

Human Genetics Unit, Indian Statistical Institute, Kolkata, West Bengal, India.

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http://doi.wiley.com/10.1002/gepi.21930
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http://dx.doi.org/10.1002/gepi.21930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958458PMC
December 2015

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

J Natl Cancer Inst 2015 Nov 29;107(11). Epub 2015 Aug 29.

: Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada (RJH, YB, JGP); National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany (CMU, AR); Mayo Clinic, Rochester, MN (ELG, DNR); The University of Warwick, Coventry, UK (KM); Massachusetts General Hospital, Boston, MA (ATC); University of Hawaii Cancer Center, Honolulu, HI (LLM); Duke University, Durham, NC (JS); University of California at San Francisco, San Francisco, CA (JSW); Institute of Cancer Research, London, UK (RE, RH, ZKJ); Mount Sinai School of Medicine, New York, NY (PBo); Baylor College of Medicine, Houston, TX (MRS); Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS (BLF); Moffitt Cancer Center, Tampa, FL (ZC, CP, TAS); University of South California, Los Angeles, CA (CH, FS, GC, SBG, BH); Cambridge University, Cambridge, UK (DFE, AAAO, HS); National Cancer Institute, Bethesda, MD (MTL, SC, SIB, NW); International Agency for Research on Cancer, Lyon, France (PBr); Harvard School of Public Health, Boston, MA (DCC, PK, SL, DJH); University of Liverpool, Liverpool, UK (JKF); University of Göttingen, Medical School, Göttingen, Germany (HB); Karolinska Institutet, Stockholm, Sweden (FW, HG); Fred Hutchinson Cancer Research Center, Seattle, WA (UP); University of Utah Health Sciences Center and Huntsman Cancer Institute, Salt Lake City, UT (CMU, MLS); Geisel School of Medicine, Dartmouth College, Lebanon, NH (CIA).

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http://jnci.oxfordjournals.org/content/107/11/djv246.full.pd
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv24
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http://dx.doi.org/10.1093/jnci/djv246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675100PMC
November 2015

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.

Hum Mol Genet 2015 Oct 10;24(19):5603-18. Epub 2015 Jul 10.

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center,

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http://dx.doi.org/10.1093/hmg/ddv269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572069PMC
October 2015

Strategies for Imputing and Analyzing Rare Variants in Association Studies.

Trends Genet 2015 Oct;31(10):556-563

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94158, USA; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, 94143 USA; Department of Urology, University of California San Francisco, San Francisco, CA 94158, USA; UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94158, USA.

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October 2015

Detecting gene-environment interactions in human birth defects: Study designs and statistical methods.

Birth Defects Res A Clin Mol Teratol 2015 Aug 23;103(8):692-702. Epub 2015 May 23.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.

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August 2015

Developments in our understanding of the genetic basis of birth defects.

Birth Defects Res A Clin Mol Teratol 2015 Aug 28;103(8):680-91. Epub 2015 May 28.

Division of Birth Defects Research, Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537658PMC
August 2015

A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.

Cancer Discov 2015 Aug 1;5(8):878-91. Epub 2015 Jun 1.

Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California. Institute for Human Genetics, University of California, San Francisco, San Francisco, California. Department of Urology, University of California, San Francisco, San Francisco, California. UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527942PMC
August 2015

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

PLoS One 2014 31;9(10):e110569. Epub 2014 Oct 31.

Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Research Center for Genes, Environment and Human Health, College of Public Health, National Taiwan University, Taipei, Taiwan; Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215920PMC
June 2015

Replication and heritability of prostate cancer risk variants: impact of population-specific factors.

Cancer Epidemiol Biomarkers Prev 2015 Jun 25;24(6):938-43. Epub 2015 Mar 25.

Department of Epidemiology and Biostatistics, University of California, San Francisco, California. Institute for Human Genetics, University of California, San Francisco, California. Department of Urology, University of California, San Francisco, California. UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

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June 2015

Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population.

J Urol 2015 May 21;193(5):1625-31. Epub 2014 Nov 21.

Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California.

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May 2015

Selenoprotein and antioxidant genes and the risk of high-grade prostate cancer and prostate cancer recurrence.

Prostate 2015 Jan 4;75(1):60-9. Epub 2014 Oct 4.

Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, California.

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January 2015

Population genetic simulations of complex phenotypes with implications for rare variant association tests.

Genet Epidemiol 2015 Jan 21;39(1):35-44. Epub 2014 Nov 21.

Graduate Program in Bioinformatics, University of California, San Francisco, California, United States of America.

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January 2015

Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort.

PLoS Genet 2015 Jan 28;11(1):e1004930. Epub 2015 Jan 28.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America; Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America; Department of Urology, University of California San Francisco, San Francisco, California, United States of America.

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January 2015

The contribution of genetic variants to disease depends on the ruler.

Nat Rev Genet 2014 11 16;15(11):765-76. Epub 2014 Sep 16.

Queensland Brain Institute, The University of Queensland, Building 79, Research Road, Brisbane, 4072, Queensland, Australia.

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November 2014

Copy number variation in bronchopulmonary dysplasia.

Am J Med Genet A 2014 Oct 26;164A(10):2672-5. Epub 2014 Jun 26.

Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California San Francisco, San Francisco, California.

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October 2014

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Sonja I Berndt David V Conti Fredrick Schumacher Ying Han Sara Benlloch Dennis J Hazelett Zhaoming Wang Ed Saunders Daniel Leongamornlert Sara Lindstrom Sara Jugurnauth-Little Tokhir Dadaev Malgorzata Tymrakiewicz Daniel O Stram Kristin Rand Peggy Wan Alex Stram Xin Sheng Loreall C Pooler Karen Park Lucy Xia Jonathan Tyrer Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Merideth Yeager Laurie Burdette Charles C Chung Amy Hutchinson Kai Yu Chee Goh Mahbubl Ahmed Koveela Govindasami Michelle Guy Teuvo L J Tammela Anssi Auvinen Tiina Wahlfors Johanna Schleutker Tapio Visakorpi Katri A Leinonen Jianfeng Xu Markus Aly Jenny Donovan Ruth C Travis Tim J Key Afshan Siddiq Federico Canzian Kay-Tee Khaw Atsushi Takahashi Michiaki Kubo Paul Pharoah Nora Pashayan Maren Weischer Borge G Nordestgaard Sune F Nielsen Peter Klarskov Martin Andreas Røder Peter Iversen Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Janet L Stanford Suzanne Kolb Sarah Holt Beatrice Knudsen Antonio Hurtado Coll Susan M Gapstur W Ryan Diver Victoria L Stevens Christiane Maier Manuel Luedeke Kathleen Herkommer Antje E Rinckleb Sara S Strom Curtis Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Lisa Cannon-Albright Cezary Cybulski Dominika Wokołorczyk Wojciech Kluźniak Jong Park Thomas Sellers Hui-Yi Lin William B Isaacs Alan W Partin Hermann Brenner Aida Karina Dieffenbach Christa Stegmaier Constance Chen Edward L Giovannucci Jing Ma Meir Stampfer Kathryn L Penney Lorelei Mucci Esther M John Sue A Ingles Rick A Kittles Adam B Murphy Hardev Pandha Agnieszka Michael Andrzej M Kierzek William Blot Lisa B Signorello Wei Zheng Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Barbara Nemesure John Carpten Cristina Leske Suh-Yuh Wu Anselm Hennis Adam S Kibel Benjamin A Rybicki Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein S Lilly Zheng Jyotsna Batra Judith Clements Amanda Spurdle Manuel R Teixeira Paula Paulo Sofia Maia Chavdar Slavov Radka Kaneva Vanio Mitev John S Witte Graham Casey Elizabeth M Gillanders Daniella Seminara Elio Riboli Freddie C Hamdy Gerhard A Coetzee Qiyuan Li Matthew L Freedman David J Hunter Kenneth Muir Henrik Gronberg David E Neal Melissa Southey Graham G Giles Gianluca Severi Michael B Cook Hidewaki Nakagawa Fredrik Wiklund Peter Kraft Stephen J Chanock Brian E Henderson Douglas F Easton Rosalind A Eeles Christopher A Haiman

Nat Genet 2014 Oct 14;46(10):1103-9. Epub 2014 Sep 14.

1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [2] Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. [3].

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383163PMC
October 2014

Plasma antioxidants, genetic variation in SOD2, CAT, GPX1, GPX4, and prostate cancer survival.

Cancer Epidemiol Biomarkers Prev 2014 Jun 7;23(6):1037-46. Epub 2014 Apr 7.

Authors' Affiliations: Departments of Epidemiology and Biostatistics, Urology, University of California, San Francisco, California; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Departments of Epidemiology, and Nutrition, Harvard School of Public Health, Boston, Massachusetts; and Department of Food Science and Human Nutrition, University of Illinois, Urbana, IllinoisAuthors' Affiliations: Departments of Epidemiology and Biostatistics, Urology, University of California, San Francisco, California; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; Departments of Epidemiology, and Nutrition, Harvard School of Public Health, Boston, Massachusetts; and Department of Food Science and Human Nutrition, University of Illinois, Urbana, Illinois.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047147PMC
June 2014

Genetic epidemiology and nonsyndromic structural birth defects: from candidate genes to epigenetics.

JAMA Pediatr 2014 Apr;168(4):371-7

Department of Pathology and Cell Biology, Institute for Cancer Genetics, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1001/jamapediatrics.2013.4858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981910PMC
April 2014

Antioxidant and vitamin E transport genes and risk of high-grade prostate cancer and prostate cancer recurrence.

Prostate 2013 Dec 29;73(16):1786-95. Epub 2013 Aug 29.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1002/pros.22717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501162PMC
December 2013

Hypospadias and genes related to genital tubercle and early urethral development.

J Urol 2013 Nov 30;190(5):1884-92. Epub 2013 May 30.

Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103581PMC
November 2013

Does accounting for gene-environment interactions help uncover association between rare variants and complex diseases?

Hum Hered 2012 11;74(3-4):205-14. Epub 2013 Apr 11.

Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, CA, USA.

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October 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

Association of the innate immunity and inflammation pathway with advanced prostate cancer risk.

PLoS One 2012 14;7(12):e51680. Epub 2012 Dec 14.

Department of Epidemiology, and Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522730PMC
June 2013

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

Authors:
Keri L Monda Gary K Chen Kira C Taylor Cameron Palmer Todd L Edwards Leslie A Lange Maggie C Y Ng Adebowale A Adeyemo Matthew A Allison Lawrence F Bielak Guanjie Chen Mariaelisa Graff Marguerite R Irvin Suhn K Rhie Guo Li Yongmei Liu Youfang Liu Yingchang Lu Michael A Nalls Yan V Sun Mary K Wojczynski Lisa R Yanek Melinda C Aldrich Adeyinka Ademola Christopher I Amos Elisa V Bandera Cathryn H Bock Angela Britton Ulrich Broeckel Quiyin Cai Neil E Caporaso Chris S Carlson John Carpten Graham Casey Wei-Min Chen Fang Chen Yii-Der I Chen Charleston W K Chiang Gerhard A Coetzee Ellen Demerath Sandra L Deming-Halverson Ryan W Driver Patricia Dubbert Mary F Feitosa Ye Feng Barry I Freedman Elizabeth M Gillanders Omri Gottesman Xiuqing Guo Talin Haritunians Tamara Harris Curtis C Harris Anselm J M Hennis Dena G Hernandez Lorna H McNeill Timothy D Howard Barbara V Howard Virginia J Howard Karen C Johnson Sun J Kang Brendan J Keating Suzanne Kolb Lewis H Kuller Abdullah Kutlar Carl D Langefeld Guillaume Lettre Kurt Lohman Vaneet Lotay Helen Lyon Joann E Manson William Maixner Yan A Meng Kristine R Monroe Imran Morhason-Bello Adam B Murphy Josyf C Mychaleckyj Rajiv Nadukuru Katherine L Nathanson Uma Nayak Amidou N'diaye Barbara Nemesure Suh-Yuh Wu M Cristina Leske Christine Neslund-Dudas Marian Neuhouser Sarah Nyante Heather Ochs-Balcom Adesola Ogunniyi Temidayo O Ogundiran Oladosu Ojengbede Olufunmilayo I Olopade Julie R Palmer Edward A Ruiz-Narvaez Nicholette D Palmer Michael F Press Evandine Rampersaud Laura J Rasmussen-Torvik Jorge L Rodriguez-Gil Babatunde Salako Eric E Schadt Ann G Schwartz Daniel A Shriner David Siscovick Shad B Smith Sylvia Wassertheil-Smoller Elizabeth K Speliotes Margaret R Spitz Lara Sucheston Herman Taylor Bamidele O Tayo Margaret A Tucker David J Van Den Berg Digna R Velez Edwards Zhaoming Wang John K Wiencke Thomas W Winkler John S Witte Margaret Wrensch Xifeng Wu James J Yang Albert M Levin Taylor R Young Neil A Zakai Mary Cushman Krista A Zanetti Jing Hua Zhao Wei Zhao Yonglan Zheng Jie Zhou Regina G Ziegler Joseph M Zmuda Jyotika K Fernandes Gary S Gilkeson Diane L Kamen Kelly J Hunt Ida J Spruill Christine B Ambrosone Stefan Ambs Donna K Arnett Larry Atwood Diane M Becker Sonja I Berndt Leslie Bernstein William J Blot Ingrid B Borecki Erwin P Bottinger Donald W Bowden Gregory Burke Stephen J Chanock Richard S Cooper Jingzhong Ding David Duggan Michele K Evans Caroline Fox W Timothy Garvey Jonathan P Bradfield Hakon Hakonarson Struan F A Grant Ann Hsing Lisa Chu Jennifer J Hu Dezheng Huo Sue A Ingles Esther M John Joanne M Jordan Edmond K Kabagambe Sharon L R Kardia Rick A Kittles Phyllis J Goodman Eric A Klein Laurence N Kolonel Loic Le Marchand Simin Liu Barbara McKnight Robert C Millikan Thomas H Mosley Badri Padhukasahasram L Keoki Williams Sanjay R Patel Ulrike Peters Curtis A Pettaway Patricia A Peyser Bruce M Psaty Susan Redline Charles N Rotimi Benjamin A Rybicki Michèle M Sale Pamela J Schreiner Lisa B Signorello Andrew B Singleton Janet L Stanford Sara S Strom Michael J Thun Mara Vitolins Wei Zheng Jason H Moore Scott M Williams Shamika Ketkar Xiaofeng Zhu Alan B Zonderman Charles Kooperberg George J Papanicolaou Brian E Henderson Alex P Reiner Joel N Hirschhorn Ruth J F Loos Kari E North Christopher A Haiman

Nat Genet 2013 Jun 14;45(6):690-6. Epub 2013 Apr 14.

The Center for Observational Research, Amgen, Inc. Thousand Oaks, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694490PMC
June 2013

The Covariate's Dilemma.

PLoS Genet 2012 8;8(11):e1003096. Epub 2012 Nov 8.

Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497901PMC
May 2013

The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies.

Genet Epidemiol 2013 May 25;37(4):383-92. Epub 2013 Mar 25.

Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94158-9001, USA.

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http://dx.doi.org/10.1002/gepi.21724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291231PMC
May 2013

HOXB13 mutation and prostate cancer: studies of siblings and aggressive disease.

Cancer Epidemiol Biomarkers Prev 2013 Apr 8;22(4):675-80. Epub 2013 Feb 8.

Departments of Epidemiology & Biostatistics and Urology, University of California San Francisco, San Francisco, CA 94158, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617049PMC
April 2013

Turning of COGS moves forward findings for hormonally mediated cancers.

Nat Genet 2013 Apr;45(4):345-8

Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.

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April 2013

Diacylglycerol kinase K variants impact hypospadias in a California study population.

J Urol 2013 Jan 21;189(1):305-11. Epub 2012 Nov 21.

Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine, Stanford, California 94305-5415, USA.

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http://dx.doi.org/10.1016/j.juro.2012.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973486PMC
January 2013

Rare genetic variants and treatment response: sample size and analysis issues.

Authors:
John S Witte

Stat Med 2012 Nov 27;31(25):3041-50. Epub 2012 Jun 27.

Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California, San Francisco, CA 94143, U.S.A.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766744PMC
November 2012

Reclassify controls at your own risk.

Epidemiology 2012 Nov;23(6):910-1

Department of Epidemiology & Biostatistics, Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94158-9001, USA.

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November 2012

Joint association testing of common and rare genetic variants using hierarchical modeling.

Genet Epidemiol 2012 Sep 16;36(6):642-51. Epub 2012 Jul 16.

Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California, San Francisco, California 94158-9001, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339046PMC
September 2012

The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury.

Chest 2012 May 29;141(5):1160-1169. Epub 2011 Dec 29.

Division of Pulmonary and Critical Care, University of California, San Francisco, San Francisco, CA; Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342784PMC
May 2012

Impact of meat consumption, preparation, and mutagens on aggressive prostate cancer.

PLoS One 2011 23;6(11):e27711. Epub 2011 Nov 23.

Department of Urology, University of California San Francisco, San Francisco, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223211PMC
April 2012

A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis.

PLoS One 2011 30;6(11):e28408. Epub 2011 Nov 30.

Department of Molecular and Cellular Biology, California Institute for Quantitative Biosciences, University of California, Berkeley, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227667PMC
April 2012

Copy number alterations in prostate tumors and disease aggressiveness.

Genes Chromosomes Cancer 2012 Jan 2;51(1):66-76. Epub 2011 Oct 2.

Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.

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http://dx.doi.org/10.1002/gcc.20932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209417PMC
January 2012

Impact of consumption of vegetable, fruit, grain, and high glycemic index foods on aggressive prostate cancer risk.

Nutr Cancer 2011 20;63(6):860-72. Epub 2011 Jul 20.

Department of Epidemiology, University of California at San Francisco, San Francisco, California 94158-9001, USA.

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http://www.tandfonline.com/doi/abs/10.1080/01635581.2011.582
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http://dx.doi.org/10.1080/01635581.2011.582224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209415PMC
December 2011

Use of principal components to aggregate rare variants in case-control and family-based association studies in the presence of multiple covariates.

BMC Proc 2011 Nov 29;5 Suppl 9:S29. Epub 2011 Nov 29.

Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California San Francisco, 1450 Third Street, Box 3110, San Francisco, CA 94148-3110, USA.

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http://dx.doi.org/10.1186/1753-6561-5-S9-S29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287864PMC
November 2011

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.

PLoS Genet 2011 Oct 6;7(10):e1002298. Epub 2011 Oct 6.

Montreal Heart Institute, Montréal, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1002298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188544PMC
October 2011

The landscape of recombination in African Americans.

Nature 2011 Jul 20;476(7359):170-5. Epub 2011 Jul 20.

Wellcome Trust Centre for Human Genetics, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/nature10336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154982PMC
July 2011

Of models and methods.

Authors:
John S Witte

Cancer Epidemiol Biomarkers Prev 2011 Jun;20(6):1059-60

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0362DOI Listing
June 2011