Publications by authors named "John S Parks"

100Publications

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.

Mol Cell 2020 10 5;80(2):263-278.e7. Epub 2020 Oct 5.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Institute of Basic Medical Science, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 41354, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2020.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534735PMC
October 2020

Human GDPD3 overexpression promotes liver steatosis by increasing lysophosphatidic acid production and fatty acid uptake.

J Lipid Res 2020 Jul 19;61(7):1075-1086. Epub 2020 May 19.

Section on Molecular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157.

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http://dx.doi.org/10.1194/jlr.RA120000760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328041PMC
July 2020

Solute Carrier Family 37 Member 2 (SLC37A2) Negatively Regulates Murine Macrophage Inflammation by Controlling Glycolysis.

iScience 2020 May 4;23(5):101125. Epub 2020 May 4.

Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232099PMC
May 2020

Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor.

Arterioscler Thromb Vasc Biol 2019 09 6;39(9):1747-1761. Epub 2019 Jun 6.

From the Department of Internal Medicine, Section of Molecular Medicine (A.C.B., M.L., C-C.C.K., E.B., X.W., J.K.S., J.S.P.), Wake Forest School of Medicine, Winston-Salem, NC.

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http://dx.doi.org/10.1161/ATVBAHA.119.312382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703909PMC
September 2019

Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans.

Diabetes 2019 07 22;68(7):1508-1522. Epub 2019 Apr 22.

Section of Endocrinology and Metabolism, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC

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http://dx.doi.org/10.2337/db18-1229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609988PMC
July 2019

Genetic Polymorphisms Associated with Idiopathic Short Stature and First-Year Response to Growth Hormone Treatment.

Horm Res Paediatr 2019 10;91(3):164-174. Epub 2019 Apr 10.

Pediatric Endocrinology, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1159/000496989DOI Listing
December 2019

Gene Sequence and Production of Recombinant MetGH/hGH.

Authors:
John S Parks

Pediatr Endocrinol Rev 2018 Sep;16(Suppl 1):17-27

Emeritus Professor of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA, E-mail:

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https://www.pediatricendoreviews.com/
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http://dx.doi.org/10.17458/per.vol16.2018.p.sequenceproductionmetghDOI Listing
September 2018

Feeding of tobacco blend or nicotine induced weight loss associated with decreased adipocyte size and increased physical activity in male mice.

Food Chem Toxicol 2018 Mar 5;113:287-295. Epub 2018 Feb 5.

Departments of Internal Medicine, Section on Molecular Medicine, Winston-Salem, NC 27157, USA; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2018.01.058DOI Listing
March 2018

Congenital Hypopituitarism.

Authors:
John S Parks

Clin Perinatol 2018 03;45(1):75-91

Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clp.2017.11.001DOI Listing
March 2018

Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity.

Arterioscler Thromb Vasc Biol 2018 04 18;38(4):733-743. Epub 2018 Jan 18.

From the Section on Molecular Medicine, Department of Internal Medicine (H.C., M.L., C.-C.C.K., E.B., J.K.S., A.W., A.B., J.S.P.) and Department of Biochemistry (J.S.P.), Wake Forest School of Medicine, Winston-Salem, NC; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York (S.K.F.); and Department of Nutrition and Health Sciences, University of Nebraska, Lincoln, NE (S.C.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864538PMC
April 2018

Δ-5 Fatty Acid Desaturase Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators.

Arterioscler Thromb Vasc Biol 2018 01 26;38(1):218-231. Epub 2017 Oct 26.

From the Department of Cellular and Molecular Medicine, Lerner Research Institute (A.D.G., R.C.S., A.L.B., R.N.H., A.C.B., D.F., R.Z., R.E.M., J.M.B.) and Department of Anatomical Pathology (D.S.A.), Cleveland Clinic, OH; Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (B.E.S., M.S.); Cardiovascular Group, Antisense Drug Discovery, Ionis Pharmaceuticals, Inc, Carlsbad, CA (R.G.L.); and Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC (J.S.P.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746431PMC
January 2018

Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol.

Gene 2017 Oct 26;632:50-58. Epub 2017 Aug 26.

Department of Internal Medicine, Section on Endocrinology and Metabolism, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600164PMC
October 2017

Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Oct 8;1862(10 Pt A):1035-1043. Epub 2017 Jul 8.

Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1016/j.bbalip.2017.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726374PMC
October 2017

Slfn2 mutation-induced loss of T-cell quiescence leads to elevated de novo sterol synthesis.

Immunology 2017 11 2;152(3):484-493. Epub 2017 Aug 2.

The Lautenberg Centre for Immunology and Cancer Research, The Biomedical Research Institute Israel Canada of the Faculty of Medicine, The Hebrew University Hadassah Medical School Jerusalem, Jerusalem, Israel.

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http://dx.doi.org/10.1111/imm.12785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629436PMC
November 2017

Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.

Cell Rep 2017 06;19(10):2116-2129

Section on Molecular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512440PMC
June 2017

Quercetin, a functional compound of onion peel, remodels white adipocytes to brown-like adipocytes.

J Nutr Biochem 2017 04 12;42:62-71. Epub 2017 Jan 12.

Food and Nutritional Sciences, Department of Family and Consumer Sciences, North Carolina Agricultural and Technical State University, Greensboro, NC, 27411. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2016.12.018DOI Listing
April 2017

In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice.

J Lipid Res 2017 01 3;58(1):236-246. Epub 2016 Nov 3.

Departments of Internal Medicine/Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157

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http://dx.doi.org/10.1194/jlr.M072769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234726PMC
January 2017

MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains.

J Biol Chem 2016 09 28;291(37):19651-60. Epub 2016 Jul 28.

From the Immunity, Inflammation and Disease Laboratory, NIEHS, National Institutes of Health, Research Triangle Park, North Carolina 27709,

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http://dx.doi.org/10.1074/jbc.M116.723056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016698PMC
September 2016

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.

Arterioscler Thromb Vasc Biol 2016 07 19;36(7):1328-37. Epub 2016 May 19.

From the Division of Molecular Medicine, Department of Medicine (M.W., P.F., A.E.B., M.M.M., V.N., S.A., C.L.W., A.R.T.), Naomi Berrie Diabetes Center (K.T., D.A.), and Department of Pathology, Obstetrics, and Gynaecology (I.W.T., J.K.), Columbia University, New York, NY; Section on Molecular Genetics, Department of Pediatrics, University Medical Center Groningen, Groningen, The Netherlands (M.W.); Department of Diabetes, Endocrinology, and Metabolism, Medical Hospital of Tokyo Medical and Dental University, Tokyo, Japan (K.T.); and Section on Molecular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (J.S.P.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919153PMC
July 2016

Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice.

Diabetes 2016 06 28;65(6):1565-76. Epub 2016 Jan 28.

Department of Biology and Center for Obesity Reversal, Georgia State University, Atlanta, GA

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http://dx.doi.org/10.2337/db15-0917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878417PMC
June 2016

Dietary cholesterol effects on adipose tissue inflammation.

Curr Opin Lipidol 2016 Feb;27(1):19-25

aDepartment of Nutrition and Health Sciences, University of Nebraska, Lincoln, Nebraska, USA bDepartments of Internal Medicine/Molecular Medicine cBiochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1097/MOL.0000000000000260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703484PMC
February 2016

Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.

J Lipid Res 2015 Aug 18;56(8):1583-93. Epub 2015 Jun 18.

Department of Internal Medicine, Sections on Molecular Medicine Wake Forest School of Medicine, Winston-Salem, NC.

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http://www.jlr.org/content/56/8/1583.full.pdf
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http://www.jlr.org/lookup/doi/10.1194/jlr.M059733
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http://dx.doi.org/10.1194/jlr.M059733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513999PMC
August 2015

Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver.

J Lipid Res 2015 Jun 28;56(6):1191-205. Epub 2015 Apr 28.

Departments of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157 Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157.

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http://dx.doi.org/10.1194/jlr.M059170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442876PMC
June 2015

Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles.

J Biol Chem 2015 Mar 27;290(12):7861-70. Epub 2015 Jan 27.

From the Department of Internal Medicine, Section on Molecular Medicine, and the Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157 and

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http://dx.doi.org/10.1074/jbc.M114.631101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367285PMC
March 2015

Inhibiting DNA Methylation by 5-Aza-2'-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation.

Endocrinology 2014 Dec 24;155(12):4925-38. Epub 2014 Sep 24.

Department of Biology and Center for Obesity Reversal (Q.C., H.S., B.X.), Georgia State University, Atlanta, Georgia; Departments of Internal Medicine (Q.C., X.W., A.K.M., A.D., G.A.H., S.K.D., H.S., B.X.) and Pathology (J.S.P.), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Internal Medicine (L.J.), University of Texas, Southwestern Medical Center, Dallas, Texas; Department of Animal and Avian Sciences (L.Y.), University of Maryland, College Park, Maryland; and Department of Biochemistry and Molecular Biology (H.S.), Georgia Regents University, Augusta, Georgia.

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http://dx.doi.org/10.1210/en.2014-1595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239421PMC
December 2014

A novel TRPS1 gene mutation causing trichorhinophalangeal syndrome with growth hormone responsive short stature: a case report and review of the literature.

Int J Pediatr Endocrinol 2014 15;2014(1):16. Epub 2014 Aug 15.

Division of Endocrinology and Diabetes, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1186/1687-9856-2014-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148676PMC
September 2014

Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development.

Arterioscler Thromb Vasc Biol 2014 Sep 17;34(9):1871-9. Epub 2014 Jul 17.

From the Departments of Internal Medicine/Rheumatology and Immunology (Q.C., N.M.), Pathology/Lipid Sciences (S.R., R.S.C., J.S.P.), and Biochemistry (J.S.P.), Wake Forest School of Medicine, Winston-Salem, NC; and Departments of Internal Medicine and Physiology, The University of Texas Southwestern Medical Center, Dallas (J.J.R.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217086PMC
September 2014

Dietary cholesterol promotes adipocyte hypertrophy and adipose tissue inflammation in visceral, but not in subcutaneous, fat in monkeys.

Arterioscler Thromb Vasc Biol 2014 Sep 26;34(9):1880-7. Epub 2014 Jun 26.

From the Department of Pathology, Sections on Lipid Sciences (S.C., H.C., S.M.M., A.L.M., R.E.T., J.S.P.) and Comparative Medicine (K.K.), and Department of Biochemistry (J.S.P.), Wake Forest School of Medicine, Winston-Salem, NC; Department of Nutrition and Health Sciences, University of Nebraska, Lincoln (S.C.); Department of Food Science and Human Nutrition, University of Florida, Gainesville (S.C., J.-H.H.); and Department of Pathology and Laboratory Medicine, Howard Hughes Medical Institute, University of California, Los Angeles (C.H., P.T.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140949PMC
September 2014

Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice.

Arterioscler Thromb Vasc Biol 2014 Sep 15;34(9):1888-99. Epub 2014 May 15.

From the Department of Pathology/Section on Lipid Sciences (X.B., X.Z., C.G., S.S., Q.C., M.L., E.B., A.K.G., M.D.W., A.L.B., J.S.P.) and Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC (J.S.P.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.114.303791
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http://dx.doi.org/10.1161/ATVBAHA.114.303791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140956PMC
September 2014

Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice.

J Biol Chem 2013 Oct 9;288(42):30432-44. Epub 2013 Sep 9.

From the Departments of Cell Biology and Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York 11203 and.

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http://dx.doi.org/10.1074/jbc.M113.501247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798507PMC
October 2013

Liver ABCA1 deletion in LDLrKO mice does not impair macrophage reverse cholesterol transport or exacerbate atherogenesis.

Arterioscler Thromb Vasc Biol 2013 Oct 27;33(10):2288-96. Epub 2013 Jun 27.

From the Section on Lipid Sciences, Department of Pathology (X.B., X.Z., M.D., E.Y.B., M.D.W., A.K.G., J.S.P.), and Department of Biochemistry (J.S.P.), Wake Forest School of Medicine, Winston-Salem, NC.

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http://dx.doi.org/10.1161/ATVBAHA.112.301110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793209PMC
October 2013

Increased cholesterol content in gammadelta (γδ) T lymphocytes differentially regulates their activation.

PLoS One 2013 21;8(5):e63746. Epub 2013 May 21.

Division of Inflammation Biology, La Jolla Institute for Allergy & Immunology, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063746PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660587PMC
December 2013

ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development.

J Immunol 2012 Dec 24;189(11):5129-38. Epub 2012 Oct 24.

Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.4049/jimmunol.1201570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776580PMC
December 2012

The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence.

Cell Rep 2012 Jan 26;1(1):56-68. Epub 2012 Jan 26.

Immunobiology Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA.

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http://dx.doi.org/10.1016/j.celrep.2011.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883512PMC
January 2012

Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions.

Arterioscler Thromb Vasc Biol 2012 Sep 19;32(9):2122-30. Epub 2012 Jul 19.

Department of Pathology, Section on Lipid Sciences, Wake Forest School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157-1040, USA.

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http://dx.doi.org/10.1161/ATVBAHA.112.253435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431287PMC
September 2012

Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers.

J Lipid Res 2012 Sep 29;53(9):1890-909. Epub 2012 Jun 29.

Department of Pathology, Section on Lipid Sciences, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1194/jlr.M026674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413229PMC
September 2012

New roles of HDL in inflammation and hematopoiesis.

Annu Rev Nutr 2012 Aug 23;32:161-82. Epub 2012 Apr 23.

Department of Pathology-Section on Lipid Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1146/annurev-nutr-071811-150709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830451PMC
August 2012

Hepatic ABC transporters and triglyceride metabolism.

Curr Opin Lipidol 2012 Jun;23(3):196-200

Department of Pathology/Section on Lipid Sciences, Wake Forest School of Medicine, Medical Center Blvd.,Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1097/MOL.0b013e328352dd1aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793202PMC
June 2012

Echium oil reduces atherosclerosis in apoB100-only LDLrKO mice.

Atherosclerosis 2012 Jan 29;220(1):118-21. Epub 2011 Oct 29.

Department of Pathology/Section on Lipid Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258669PMC
January 2012

Hepatic ABCA1 and VLDL triglyceride production.

Biochim Biophys Acta 2012 May 6;1821(5):770-7. Epub 2011 Oct 6.

Department of Pathology/Section on Lipid Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1016/j.bbalip.2011.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272310PMC
May 2012

Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans.

Nephrol Dial Transplant 2011 Nov 19;26(11):3805-10. Epub 2011 Sep 19.

Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1093/ndt/gfr542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203631PMC
November 2011

Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo.

Circulation 2011 Oct 19;124(15):1663-72. Epub 2011 Sep 19.

Department of Pathology/Section on Lipid Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.025445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202242PMC
October 2011

Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling.

J Immunol 2011 Aug;187(4):1529-35

Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1100253
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http://dx.doi.org/10.4049/jimmunol.1100253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151145PMC
August 2011

Lipotoxicity in diabetic nephropathy: the potential role of fatty acid oxidation.

Clin J Am Soc Nephrol 2010 Dec 4;5(12):2373-9. Epub 2010 Nov 4.

Department of Internal Medicine/Nephrology Section, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina 27157-1053, USA.

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http://dx.doi.org/10.2215/CJN.08160910DOI Listing
December 2010

The impact of transient hypothyroidism on the increasing rate of congenital hypothyroidism in the United States.

Pediatrics 2010 May;125 Suppl 2:S54-63

Division of Pediatric Endocrinology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1542/peds.2009-1975FDOI Listing
May 2010

ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions.

Arterioscler Thromb Vasc Biol 2010 Apr 28;30(4):809-17. Epub 2010 Jan 28.

Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.199166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862679PMC
April 2010

Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11.

J Lipid Res 2010 Apr 27;51(4):849-55. Epub 2009 Oct 27.

Department of Pathology Section on Lipid Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.

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http://dx.doi.org/10.1194/jlr.D002709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842150PMC
April 2010

An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2.

Mol Cell Biol 2009 Nov 14;29(22):5989-97. Epub 2009 Sep 14.

Department of Biology, Virginia Tech, Blacksburg, VA 24061, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772564PMC
November 2009

Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.

Arterioscler Thromb Vasc Biol 2009 Apr 5;29(4):548-54. Epub 2009 Feb 5.

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada.

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April 2009

Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons.

Am J Physiol Cell Physiol 2009 Jan 29;296(1):C97-105. Epub 2008 Oct 29.

Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA.

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http://www.physiology.org/doi/10.1152/ajpcell.00366.2008
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636993PMC
January 2009

LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

Cell 2008 Jul;134(1):97-111

Howard Hughes Medical Institute, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90049, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626438PMC
July 2008

Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.

J Lipid Res 2008 Nov 25;49(11):2390-401. Epub 2008 Jun 25.

Department of Pathology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1194/jlr.M800241-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563212PMC
November 2008

Mechanisms by which botanical lipids affect inflammatory disorders.

Am J Clin Nutr 2008 Feb;87(2):498S-503S

Center for Botanical Lipids, Wake Forest University, Winston Salem, NC, USA.

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February 2008

Echium oil reduces plasma lipids and hepatic lipogenic gene expression in apoB100-only LDL receptor knockout mice.

J Nutr Biochem 2008 Oct 21;19(10):655-63. Epub 2007 Dec 21.

Section on Lipid Sciences, Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.jnutbio.2007.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610363PMC
October 2008

The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction.

Nat Struct Mol Biol 2007 Sep 5;14(9):861-8. Epub 2007 Aug 5.

Department of Cell Biology, Cleveland Clinic, 9500 Euclid Avenue, NE-10, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/nsmb1284DOI Listing
September 2007

Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1.

Arterioscler Thromb Vasc Biol 2007 Aug 17;27(8):1828-36. Epub 2007 May 17.

Department of Pathology/Section on Lipid Sciences, Wake Forest University Health Sciences, Medical Center Blvd., Winston-Salem, NC 27157-1040, USA.

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August 2007

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.

Nat Med 2007 Mar 18;13(3):340-7. Epub 2007 Feb 18.

Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, British Columbia V5Z 4H4, Canada.

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March 2007

Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice.

J Lipid Res 2007 May 1;48(5):1052-61. Epub 2007 Feb 1.

Department of Pathology/Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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May 2007

Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.

Circ Res 2006 Sep 31;99(7):672-4. Epub 2006 Aug 31.

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.

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September 2006