John R Yates

John R Yates

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John R Yates

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Characterization of a novel antioxidant peptide from feather keratin hydrolysates.

N Biotechnol 2019 Mar 14;49:71-76. Epub 2018 Sep 14.

Laboratory of Biochemistry and Applied Microbiology, Federal University of Rio Grande do Sul, 91501-970 Porto Alegre, RS, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18716784183015
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http://dx.doi.org/10.1016/j.nbt.2018.09.003DOI Listing
March 2019

Understanding molecular mechanisms of disease through spatial proteomics.

Curr Opin Chem Biol 2019 Feb 9;48:19-25. Epub 2018 Oct 9.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13675931183013
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http://dx.doi.org/10.1016/j.cbpa.2018.09.016DOI Listing
February 2019

Perm1 regulates CaMKII activation and shapes skeletal muscle responses to endurance exercise training.

Mol Metab 2019 Feb 27. Epub 2019 Feb 27.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, 92037, USA; Department of Physiology, Johns Hopkins University, Baltimore, MD, 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.02.009DOI Listing
February 2019

A posttranslational modification code for CFTR maturation is altered in cystic fibrosis.

Sci Signal 2019 Jan 1;12(562). Epub 2019 Jan 1.

Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/scisignal.aan7984DOI Listing
January 2019

Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment.

iScience 2019 Jan 19;11:134-145. Epub 2018 Dec 19.

Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317279PMC
January 2019

The circadian E3 ligase complex SCF targets TLK2.

Sci Rep 2019 Jan 17;9(1):198. Epub 2019 Jan 17.

Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1038/s41598-018-36618-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336870PMC
January 2019

Tick-Host Range Adaptation: Changes in Protein Profiles in Unfed Adult and Saliva Stimulated to Feed on Different Hosts.

Front Cell Infect Microbiol 2017 19;7:517. Epub 2017 Dec 19.

Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, United States.

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http://dx.doi.org/10.3389/fcimb.2017.00517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742094PMC
December 2018

NRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells.

RNA Biol 2018 2;15(7):868-876. Epub 2018 Aug 2.

a Department of Biological Sciences , Columbia University , New York , NY , USA.

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http://dx.doi.org/10.1080/15476286.2018.1467180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161687PMC
December 2018

From Synapse to Function: A Perspective on the Role of Neuroproteomics in Elucidating Mechanisms of Drug Addiction.

Proteomes 2018 Dec 9;6(4). Epub 2018 Dec 9.

Department of Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://www.mdpi.com/2227-7382/6/4/50
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http://dx.doi.org/10.3390/proteomes6040050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315754PMC
December 2018

Innovation: Structural Proteomics Goes Global.

Authors:
John R Yates

J Proteome Res 2018 Nov 10;17(11):3613. Epub 2018 Oct 10.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00698
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http://dx.doi.org/10.1021/acs.jproteome.8b00698DOI Listing
November 2018

Secretomic analysis of Beauveria bassiana related to cattle tick, Rhipicephalus microplus, infection.

Folia Microbiol (Praha) 2018 Oct 25. Epub 2018 Oct 25.

Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av Ipiranga, 2752, Porto Alegre, RS, 90610-000, Brazil.

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http://dx.doi.org/10.1007/s12223-018-0659-3DOI Listing
October 2018

Defective RNA polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 pathway.

Elife 2018 09 7;7. Epub 2018 Sep 7.

Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, United States.

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http://dx.doi.org/10.7554/eLife.35447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128692PMC
September 2018

MIEF1 Microprotein Regulates Mitochondrial Translation.

Biochemistry 2018 Sep 14;57(38):5564-5575. Epub 2018 Sep 14.

Clayton Foundation Laboratories for Peptide Biology , The Salk Institute for Biological Studies , 10010 North Torrey Pines Road , La Jolla , California 92037 , United States.

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http://dx.doi.org/10.1021/acs.biochem.8b00726DOI Listing
September 2018

Proteomic analysis identifies highly expressed plasma membrane proteins for detection and therapeutic targeting of specific breast cancer subtypes.

Clin Proteomics 2018 19;15:30. Epub 2018 Sep 19.

1Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL USA.

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http://dx.doi.org/10.1186/s12014-018-9206-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145347PMC
September 2018

Publisher Correction: ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase.

Nature 2018 08;560(7720):E35

Howard Hughes Medical Institute, Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, CA, USA.

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http://www.nature.com/articles/s41586-018-0271-3
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http://dx.doi.org/10.1038/s41586-018-0271-3DOI Listing
August 2018

Quantitative temporal analysis of protein dynamics in cardiac remodeling.

J Mol Cell Cardiol 2018 Aug 19;121:163-172. Epub 2018 Jul 19.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.07.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239217PMC
August 2018

Innovations in Proteomics: The Drive to Single Cells.

Authors:
John R Yates

J Proteome Res 2018 Aug 19;17(8):2563-2564. Epub 2018 Jul 19.

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http://dx.doi.org/10.1021/acs.jproteome.8b00484DOI Listing
August 2018

Quantitative analysis of newly synthesized proteins.

Nat Protoc 2018 Aug;13(8):1744-1762

Departments of Molecular Medicine and Neurobiology, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41596-018-0012-yDOI Listing
August 2018

Structural Analysis of Hippocampal Kinase Signal Transduction.

ACS Chem Neurosci 2018 Aug 13. Epub 2018 Aug 13.

Department of Molecular Medicine , The Scripps Research Institute , La Jolla , California 92037 , United States.

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http://dx.doi.org/10.1021/acschemneuro.8b00284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374210PMC
August 2018

Proteomics and pulse azidohomoalanine labeling of newly synthesized proteins: what are the potential applications?

Expert Rev Proteomics 2018 07 23;15(7):545-554. Epub 2018 Jul 23.

a Departments of Molecular Medicine and Neurobiology , The Scripps Research Institute , La Jolla , CA , USA.

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http://dx.doi.org/10.1080/14789450.2018.1500902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329588PMC
July 2018

Global site-specific analysis of glycoprotein N-glycan processing.

Nat Protoc 2018 Jun 3;13(6):1196-1212. Epub 2018 May 3.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nprot.2018.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941933PMC
June 2018

Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.

Mol Cell 2018 06 31;70(5):842-853.e7. Epub 2018 May 31.

Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.04.023DOI Listing
June 2018

Secular changes in severity of intellectual disability in tuberous sclerosis complex: A reflection of improved identification and treatment of epileptic spasms?

Epilepsia Open 2018 Jun 6;3(2):276-280. Epub 2018 Apr 6.

Department of Child & Adolescent Psychiatry and MRC Social Genetic & Developmental Psychiatry Centre Institute of Psychiatry, Psychology & Neuroscience King's College London London United Kingdom.

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http://dx.doi.org/10.1002/epi4.12111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983114PMC
June 2018

Deducing the presence of proteins and proteoforms in quantitative proteomics.

Nat Commun 2018 06 13;9(1):2320. Epub 2018 Jun 13.

Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1038/s41467-018-04411-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998138PMC
June 2018

Spliceosome Profiling Visualizes Operations of a Dynamic RNP at Nucleotide Resolution.

Cell 2018 05;173(4):1014-1030.e17

Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940017PMC
May 2018

PML Recruits TET2 to Regulate DNA Modification and Cell Proliferation in Response to Chemotherapeutic Agent.

Cancer Res 2018 May 7;78(10):2475-2489. Epub 2018 May 7.

Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, Dalian, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-3091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386530PMC
May 2018

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase.

Nature 2018 05 16;557(7706):510-515. Epub 2018 May 16.

Howard Hughes Medical Institute, Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, CA, USA.

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http://www.nature.com/articles/s41586-018-0137-8
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http://dx.doi.org/10.1038/s41586-018-0137-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973781PMC
May 2018

SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.

PLoS Pathog 2018 05 23;14(5):e1007071. Epub 2018 May 23.

Regulatory Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988312PMC
May 2018

Content Is King: Databases Preserve the Collective Information of Science.

Authors:
John R Yates

J Biomol Tech 2018 04 22;29(1):1-3. Epub 2018 Mar 22.

Departments of Molecular Medicine and Neurobiology, The Scripps Research Institute, La Jolla, California, 92037, USA.

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http://dx.doi.org/10.7171/jbt.18-2901-002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863792PMC
April 2018

Identification and characterization of proteins in the Amblyomma americanum tick cement cone.

Int J Parasitol 2018 03 16;48(3-4):211-224. Epub 2017 Dec 16.

Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, TX, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00207519173034
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http://dx.doi.org/10.1016/j.ijpara.2017.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844823PMC
March 2018

The Speed of Publication.

Authors:
John R Yates

J Proteome Res 2018 03 8;17(3):935. Epub 2018 Feb 8.

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http://dx.doi.org/10.1021/acs.jproteome.8b00044DOI Listing
March 2018

Publisher Correction: Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.

Nat Commun 2018 03 13;9(1):1113. Epub 2018 Mar 13.

The Scripps Laboratories for tRNA Synthetase Research and the Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 92037, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41467-018-03594-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849694PMC
March 2018

Role of the visual experience-dependent nascent proteome in neuronal plasticity.

Elife 2018 Feb 7;7. Epub 2018 Feb 7.

The Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, United States.

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http://dx.doi.org/10.7554/eLife.33420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815848PMC
February 2018

Increased proteomic complexity in hybrids during development.

Sci Adv 2018 Feb 7;4(2):eaao3424. Epub 2018 Feb 7.

Department of Molecular Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/sciadv.aao3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810618PMC
February 2018

High infestation levels of Schizotetranychus oryzae severely affects rice metabolism.

J Plant Physiol 2017 Dec 28;219:100-111. Epub 2017 Oct 28.

Programa de Pós-Graduação em Biotecnologia (PPGBiotec), University of Taquari Valley - UNIVATES, Lajeado, RS, Brazil; Centro de Ciências Biológicas e da Saúde (CCBS), University of Taquari Valley - UNIVATES, Lajeado, RS, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.jplph.2017.10.005DOI Listing
December 2017

Profiling of Protein O-GlcNAcylation in Murine CD8 Effector- and Memory-like T Cells.

ACS Chem Biol 2017 12 10;12(12):3031-3038. Epub 2017 Nov 10.

Department of Molecular Medicine, The Scripps Research Institute , La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/acschembio.7b00869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931335PMC
December 2017

Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.

Nat Commun 2017 12 22;8(1):2281. Epub 2017 Dec 22.

The Scripps Laboratories for tRNA Synthetase Research and the Department of Molecular Medicine, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 92037, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41467-017-02201-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741666PMC
December 2017

Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.

Mol Cell Proteomics 2017 11 31;16(11):1938-1957. Epub 2017 Aug 31.

From the ‡Department of Chemical Physiology and Cell and Molecular Biology, The Scripps Research Institute, 10550, North Torrey Pines Road, La Jolla, California 92037;

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http://dx.doi.org/10.1074/mcp.M116.064949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672001PMC
November 2017

Proteomic Analysis of Peripheral Blood Mononuclear Cells after a High-Fat, High-Carbohydrate Meal with Orange Juice.

J Proteome Res 2017 11;16(11):4086-4092

Department of Food Science and Experimental Nutrition, School of Pharmaceutical Sciences, University of São Paulo , São Paulo 03178-200, Brazil.

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http://dx.doi.org/10.1021/acs.jproteome.7b00476DOI Listing
November 2017

Innovations in Publishing: Prepublication of Manuscripts on Preprint Servers.

Authors:
John R Yates

J Proteome Res 2017 11 5;16(11):3953. Epub 2017 Oct 5.

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http://dx.doi.org/10.1021/acs.jproteome.7b00674DOI Listing
November 2017

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.

Nat Commun 2017 11 13;8(1):1456. Epub 2017 Nov 13.

Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph Stelzmann Strasse 26, 50931, Cologne, Germany.

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http://dx.doi.org/10.1038/s41467-017-01744-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682285PMC
November 2017

Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos.

Nat Commun 2017 11 13;8(1):1439. Epub 2017 Nov 13.

Department of Biomolecular Chemistry, University of Wisconsin-Madison School of Medicine and Public Health, 440 Henry Mall, Madison, WI, 53706, USA.

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http://dx.doi.org/10.1038/s41467-017-01636-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682282PMC
November 2017

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.

Cell Rep 2017 Nov;21(8):2171-2182

Departments of Molecular Medicine and Neuroscience and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA; Neuroscience and Aging Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705204PMC
November 2017

CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of Treslin.

Mol Cell Biol 2017 Oct 26;37(20). Epub 2017 Sep 26.

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA

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http://dx.doi.org/10.1128/MCB.00344-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615187PMC
October 2017

Association of C-Reactive Protein Genetic Polymorphisms With Late Age-Related Macular Degeneration.

JAMA Ophthalmol 2017 09;135(9):909-916

Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, England.

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http://dx.doi.org/10.1001/jamaophthalmol.2017.2191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710541PMC
September 2017

Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.

PLoS One 2017 24;12(2):e0173013. Epub 2017 Feb 24.

Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173013PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325614PMC
August 2017

Matchmaking in Proteomics.

Authors:
John R Yates

Clin Chem 2017 07 8;63(7):1297-1298. Epub 2017 May 8.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA.

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http://dx.doi.org/10.1373/clinchem.2016.267856DOI Listing
July 2017

Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

J Cell Biol 2017 07 30;216(7):2059-2074. Epub 2017 May 30.

Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI

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http://dx.doi.org/10.1083/jcb.201604028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496608PMC
July 2017

Identification of Microprotein-Protein Interactions via APEX Tagging.

Biochemistry 2017 07 7;56(26):3299-3306. Epub 2017 Jun 7.

Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies , 10010 North Torrey Pines Road, La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/acs.biochem.7b00265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499098PMC
July 2017

Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress.

Cell Rep 2017 07;20(4):895-908

Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.06.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586494PMC
July 2017

HILAQ: A Novel Strategy for Newly Synthesized Protein Quantification.

J Proteome Res 2017 06 3;16(6):2213-2220. Epub 2017 May 3.

Department of Chemical Physiology and Molecular and Cellular Neurobiology, The Scripps Research Institute , La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718913PMC
June 2017

Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.

J Biol Chem 2017 06 1;292(25):10398-10413. Epub 2017 May 1.

From the Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037,

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http://dx.doi.org/10.1074/jbc.M117.789479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481553PMC
June 2017

Cleavage of the SUN-domain protein Mps3 at its N-terminus regulates centrosome disjunction in budding yeast meiosis.

PLoS Genet 2017 Jun 13;13(6):e1006830. Epub 2017 Jun 13.

Department of Biological Science, the Florida State University, Tallahassee, FL, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487077PMC
June 2017

MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.

Proc Natl Acad Sci U S A 2017 05 1;114(20):E4048-E4056. Epub 2017 May 1.

Neuroscience and Aging Research Center and Graduate School of Biomedical Sciences, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1613067114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441815PMC
May 2017

The protein kinase MBK-1 contributes to lifespan extension in mutant and germline-deficient .

Aging (Albany NY) 2017 05;9(5):1414-1432

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.18632/aging.101244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741PMC
May 2017

DCLK1 phosphorylates the microtubule-associated protein MAP7D1 to promote axon elongation in cortical neurons.

Dev Neurobiol 2017 04 24;77(4):493-510. Epub 2016 Nov 24.

Department of Biological Sciences, School of Science, The University of Tokyo, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1002/dneu.22428DOI Listing
April 2017

The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking.

J Cell Sci 2017 04 24;130(8):1450-1462. Epub 2017 Feb 24.

Department of Molecular Biology and Genetics, Koç University, Istanbul 34450, Turkey

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http://dx.doi.org/10.1242/jcs.196832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399785PMC
April 2017

Innovation's Mean Free Path.

Authors:
John R Yates

J Proteome Res 2017 04 24;16(4):1381-1382. Epub 2017 Mar 24.

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http://dx.doi.org/10.1021/acs.jproteome.7b00147DOI Listing
April 2017

Targeting BMK1 Impairs the Drug Resistance to Combined Inhibition of BRAF and MEK1/2 in Melanoma.

Sci Rep 2017 04 7;7:46244. Epub 2017 Apr 7.

Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China.

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http://dx.doi.org/10.1038/srep46244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384194PMC
April 2017

Chemoproteomic profiling and discovery of protein electrophiles in human cells.

Nat Chem 2017 Mar 31;9(3):234-243. Epub 2016 Oct 31.

Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nchem.2645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325178PMC
March 2017

A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges.

Curr Biol 2017 Mar 9;27(6):860-867. Epub 2017 Mar 9.

Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.01.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367925PMC
March 2017

An SMC-like protein binds and regulates Caenorhabditis elegans condensins.

PLoS Genet 2017 03 16;13(3):e1006614. Epub 2017 Mar 16.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373644PMC
March 2017

Global Analysis of Protein Expression of Inner Ear Hair Cells.

J Neurosci 2017 02 30;37(5):1320-1339. Epub 2016 Dec 30.

Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611,

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http://dx.doi.org/10.1523/JNEUROSCI.2267-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296798PMC
February 2017

The Cover Letter.

Authors:
John R Yates

J Proteome Res 2017 02 5;16(2):367. Epub 2017 Jan 5.

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http://dx.doi.org/10.1021/acs.jproteome.6b01068DOI Listing
February 2017

Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.

J Biol Chem 2017 Jan 1;292(2):611-628. Epub 2016 Dec 1.

From the Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037 and

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http://dx.doi.org/10.1074/jbc.M116.747618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241736PMC
January 2017

Characterization of a Porous Nano-electrospray Capillary Emitter at Ultra-low Flow Rates.

J Chromatogr Sci 2017 01 7;55(1):47-51. Epub 2016 Oct 7.

MTA-PE Translational Glycomics Group, University of Pannonia, Veszprem, Hungary

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http://dx.doi.org/10.1093/chromsci/bmw148DOI Listing
January 2017

Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation.

Proc Natl Acad Sci U S A 2017 01 5;114(4):E610-E618. Epub 2017 Jan 5.

Neurobiology Section, Biological Sciences Division, University of California, San Diego, La Jolla, CA 92093;

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http://dx.doi.org/10.1073/pnas.1612062114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278468PMC
January 2017

Deep interactome profiling of membrane proteins by co-interacting protein identification technology.

Nat Protoc 2016 Dec 17;11(12):2515-2528. Epub 2016 Nov 17.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nprot.2016.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444904PMC
December 2016

Focus on Bioinformatics, Software, and MS-Based "Omics," Honoring Dr. Michael J. MacCoss, Recipient of the 2015 ASMS Biemann Medal.

J Am Soc Mass Spectrom 2016 11;27(11):1715-1718

Chemical Physiology and Molecular and Cellular Neurobiology, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/s13361-016-1502-1DOI Listing
November 2016

The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines.

Nat Commun 2016 10 31;7:13282. Epub 2016 Oct 31.

Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.

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http://dx.doi.org/10.1038/ncomms13282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095516PMC
October 2016

Change...

Authors:
John R Yates

J Proteome Res 2016 08 22;15(8):2355. Epub 2016 Jul 22.

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http://dx.doi.org/10.1021/acs.jproteome.6b00640DOI Listing
August 2016

A comprehensive and scalable database search system for metaproteomics.

BMC Genomics 2016 08 16;17(1):642. Epub 2016 Aug 16.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1186/s12864-016-2855-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986259PMC
August 2016