John R Mascola

John R Mascola

UNVERIFIED PROFILE

Are you John R Mascola?   Register this Author

Register author
John R Mascola

John R Mascola

Publications by authors named "John R Mascola"

Are you John R Mascola?   Register this Author

100Publications

2803Reads

12Profile Views

Preparing for the Next Influenza Pandemic: The Development of a Universal Influenza Vaccine.

J Infect Dis 2019 Apr;219(Supplement_1):S107-S109

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jiz043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452294PMC
April 2019

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.

Immunity 2019 Mar 12;50(3):677-691.e13. Epub 2019 Mar 12.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10747613193007
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2019.02.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555550PMC
March 2019

Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.

Structure 2019 Jan 21;27(1):196-206.e6. Epub 2018 Nov 21.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics & Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10032, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09692126183036
Publisher Site
http://dx.doi.org/10.1016/j.str.2018.10.007DOI Listing
January 2019

Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Immunogenetic Considerations Underlying B-Cell Biology in the Development of a Pan-Subtype Influenza A Vaccine Targeting the Hemagglutinin Stem.

Cold Spring Harb Perspect Biol 2018 Jul 2;10(7). Epub 2018 Jul 2.

Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland 20892.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a029413DOI Listing
July 2018

Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.

PLoS Pathog 2018 07 5;14(7):e1007159. Epub 2018 Jul 5.

Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1007159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049957PMC
July 2018

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

ACS Infect Dis 2018 05 6;4(5):788-796. Epub 2018 Mar 6.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases , National Institutes of Health , 40 Convent Drive , Bethesda , Maryland 20892 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsinfecdis.7b00192DOI Listing
May 2018

HIV-1 Vaccines Based on Antibody Identification, B Cell Ontogeny, and Epitope Structure.

Immunity 2018 05;48(5):855-871

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2018.04.029DOI Listing
May 2018

Novel Vaccine Technologies: Essential Components of an Adequate Response to Emerging Viral Diseases.

JAMA 2018 Apr;319(14):1431-1432

Office of the Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
Publisher Site
http://dx.doi.org/10.1001/jama.2018.0345DOI Listing
April 2018

Exploiting glycan topography for computational design of Env glycoprotein antigenicity.

PLoS Comput Biol 2018 04 20;14(4):e1006093. Epub 2018 Apr 20.

Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1006093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931682PMC
April 2018

Longitudinal dynamics of the HIV-specific B cell response during intermittent treatment of primary HIV infection.

PLoS One 2017 15;12(3):e0173577. Epub 2017 Mar 15.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173577PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351995PMC
September 2017

The quest for an antibody-based HIV vaccine.

Immunol Rev 2017 01;275(1):5-10

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imr.12517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384259PMC
January 2017

Use of broadly neutralizing antibodies for HIV-1 prevention.

Immunol Rev 2017 01;275(1):296-312

Oregon National Primate Center, Oregon Health & Science University, Beaverton, OR, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imr.12511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314445PMC
January 2017

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

Immunol Rev 2017 01;275(1):108-128

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imr.12480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516196PMC
January 2017

An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes.

J Immunol 2016 11 10;197(10):3982-3998. Epub 2016 Oct 10.

Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1601134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117957PMC
November 2016

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption.

N Engl J Med 2016 11 9;375(21):2037-2050. Epub 2016 Nov 9.

From the University of Pennsylvania (K.J.B., D.B.S., B.S., G.H.L., E.F.K., M.B., J.A.H., P.T.) and Children's Hospital of Philadelphia (N.B.T.) - both in Philadelphia; the Laboratory of Immunoregulation (M.C.S., J.S.J., M.E.P., J.B., E.W.R., K.E.C., S.M., A.S.F., T.-W.C.), Biostatistics Research Branch (M.A.P.), Vaccine Research Center (P.J.M., S.J.O., A.R.S., N.A.D.-R., R.T.B., J.E.L., R.M.L., B.S.G., R.A.K., J.R.M.), and Division of AIDS (R.L.T.), National Institute of Allergy and Infectious Diseases and National Institutes of Health (NIH), and the Critical Care Medicine Department, Clinical Center, NIH (C.A.S., R.W.K.), Bethesda, the AIDS Clinical Trials Group, Silver Spring (K.O.), and Columbus Technologies and Services, Greenbelt (R.L.T.) - all in Maryland; Harvard T.H. Chan School of Public Health, Boston (L.J.H.); the University of Alabama at Birmingham, Birmingham (E.T.O., M.M.); Frontier Science and Technology Research Foundation, Amherst, NY (B.J.); and the University of California, San Diego, La Jolla (E.V.C.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1608243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292134PMC
November 2016

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

Bioconjug Chem 2016 10 22;27(10):2372-2385. Epub 2016 Sep 22.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland 20892, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.bioconjchem.6b00370DOI Listing
October 2016

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation.

Sci Rep 2016 10 31;6:36298. Epub 2016 Oct 31.

The Ragon Institute of Massachusetts General Hospital, The Massachusetts Institute of Technology and Harvard University, 400 Technology Square, Cambridge, MA 02139, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep36298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087089PMC
October 2016

SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts.

Front Immunol 2016 21;7:372. Epub 2016 Sep 21.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA; Department of Systems Biology, Columbia University, New York, NY, USA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2016.00372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030719PMC
September 2016

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype.

Cell Rep 2016 08 29;16(6):1485-1491. Epub 2016 Jul 29.

Viral Pathogenesis Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.07.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004740PMC
August 2016