Publications by authors named "John R Hoidal"

56Publications

Recent Advances in Curcumin Treated Non-Small Cell Lung Cancers: An Impetus of Pleiotropic Traits and Nanocarrier Aided Delivery.

Curr Med Chem 2020 Aug 24. Epub 2020 Aug 24.

Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah. United States.

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http://dx.doi.org/10.2174/0929867327666200824110332DOI Listing
August 2020

NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure.

PLoS Genet 2020 06 10;16(6):e1008756. Epub 2020 Jun 10.

Andrology and IVF Laboratories, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307791PMC
June 2020

Reductive stress impairs myogenic differentiation.

Redox Biol 2020 07 4;34:101492. Epub 2020 Mar 4.

Division of Pulmonary, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1016/j.redox.2020.101492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199008PMC
July 2020

Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction.

Antioxid Redox Signal 2020 06;32(18):1293-1312

Cardiac Aging and Redox Signaling Laboratory, Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1089/ars.2019.7808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247052PMC
June 2020

RAGE is a Critical Mediator of Pulmonary Oxidative Stress, Alveolar Macrophage Activation and Emphysema in Response to Cigarette Smoke.

Sci Rep 2019 01 18;9(1):231. Epub 2019 Jan 18.

Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1038/s41598-018-36163-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338799PMC
January 2019

Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice.

BMC Genomics 2017 07 3;18(1):509. Epub 2017 Jul 3.

Cardiac Aging & Redox Signaling Laboratory, Division of Molecular & Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, BMR2 Room 533|901 19th Street South, Birmingham, AL, 35294-2180, USA.

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http://dx.doi.org/10.1186/s12864-017-3875-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496330PMC
July 2017

Chronic Endurance Exercise Impairs Cardiac Structure and Function in Middle-Aged Mice with Impaired Nrf2 Signaling.

Front Physiol 2017 3;8:268. Epub 2017 May 3.

Cardiac Aging and Redox Signaling Laboratory, Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at BirminghamBirmingham, AL, USA.

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http://dx.doi.org/10.3389/fphys.2017.00268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413495PMC
May 2017

A biphasic effect of TNF-α in regulation of the Keap1/Nrf2 pathway in cardiomyocytes.

Redox Biol 2016 10 27;9:77-89. Epub 2016 Jun 27.

Cardiac Aging & Redox Signaling Laboratory, Division of Molecular & Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, United States; Division of Cardiovascular, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, United States; Center for Free Radical Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, United States. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2016.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961303PMC
October 2016

Disruption of nuclear factor (erythroid-derived-2)-like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle.

FASEB J 2016 05 2;30(5):1865-79. Epub 2016 Feb 2.

Cardiac Aging and Redox Signaling Laboratory, Division of Molecular and Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA; Division of Cardiovascular Medicine/Pulmonary Medicine, Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA; Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA;

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http://dx.doi.org/10.1096/fj.201500153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836373PMC
May 2016

The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms.

PLoS One 2015 24;10(3):e0121128. Epub 2015 Mar 24.

Department of Internal Medicine, Division of Geriatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America; Department of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121128PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372581PMC
April 2016

Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome.

Exp Lung Res 2015 Apr 16;41(3):155-62. Epub 2014 Dec 16.

1Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.3109/01902148.2014.983281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406221PMC
April 2015

Nrf2 deficiency promotes apoptosis and impairs PAX7/MyoD expression in aging skeletal muscle cells.

Free Radic Biol Med 2014 Jun 6;71:402-414. Epub 2014 Mar 6.

Cardiac Aging and Redox Signaling Laboratory, Division of Cardiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA; Department of Exercise & Sports Sciences, College of Health, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.02.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493911PMC
June 2014

Nrf2 deficiency prevents reductive stress-induced hypertrophic cardiomyopathy.

Cardiovasc Res 2013 Oct 12;100(1):63-73. Epub 2013 Jun 12.

Cardiac Aging and Redox Signaling Laboratory, RM # 4A100, Division of Cardiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1093/cvr/cvt150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778956PMC
October 2013

Disruption of Nrf2/ARE signaling impairs antioxidant mechanisms and promotes cell degradation pathways in aged skeletal muscle.

Biochim Biophys Acta 2012 Jun 15;1822(6):1038-50. Epub 2012 Feb 15.

Division of Cardiology, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1016/j.bbadis.2012.02.007DOI Listing
June 2012

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium.

Free Radic Biol Med 2012 Jan 20;52(2):366-76. Epub 2011 Oct 20.

Division of Cardiology & Pulmonary, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.10.440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800165PMC
January 2012

Smoking, COPD, and 3-nitrotyrosine levels of plasma proteins.

Environ Health Perspect 2011 Sep 6;119(9):1314-20. Epub 2011 Jun 6.

Cell Biology and Biochemistry, Pacific Northwest National Laboratory, Richland, Washington 99354, USA.

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https://ehp.niehs.nih.gov/doi/10.1289/ehp.1103745
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http://dx.doi.org/10.1289/ehp.1103745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230408PMC
September 2011

Receptor for advanced glycation end-products signals through Ras during tobacco smoke-induced pulmonary inflammation.

Am J Respir Cell Mol Biol 2011 Aug 3;45(2):411-8. Epub 2010 Dec 3.

Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT 84602, USA.

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http://dx.doi.org/10.1165/rcmb.2010-0231OCDOI Listing
August 2011

Receptors for advanced glycation end-products targeting protect against hyperoxia-induced lung injury in mice.

Am J Respir Cell Mol Biol 2010 May 18;42(5):545-51. Epub 2009 Jun 18.

Department of Internal Medicine, Pulmonary Division, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1165/rcmb.2008-0265OCDOI Listing
May 2010

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

Nicotine Tob Res 2009 Jul 12;11(7):785-96. Epub 2009 May 12.

Department of Medicine, Center for Tobacco Research and Intervention, University of Wisconsin School of Medicine and Public Health, 1930 Monroe Street, Suite 200, Madison, WI 53711, USA.

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http://dx.doi.org/10.1093/ntr/ntp064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699926PMC
July 2009

Identification of proteins binding to E-Box/Ku86 sites and function of the tumor suppressor SAFB1 in transcriptional regulation of the human xanthine oxidoreductase gene.

J Biol Chem 2008 Oct 4;283(44):29681-9. Epub 2008 Sep 4.

Department of Internal Medicine, Division of Respiratory, Critical Care, and Occupational Medicine, University of Utah Health Sciences Center and Veterans Affairs Medical Center, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1074/jbc.M802076200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573066PMC
October 2008

Implication of receptor for advanced glycation end product (RAGE) in pulmonary health and pathophysiology.

Respir Physiol Neurobiol 2008 Aug 11;162(3):210-5. Epub 2008 Jul 11.

Indian Institute of Science Education and Research, MGSIPA Complex, Chandigarh, Punjab 160019, India.

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http://dx.doi.org/10.1016/j.resp.2008.07.001DOI Listing
August 2008

RAGE: developmental expression and positive feedback regulation by Egr-1 during cigarette smoke exposure in pulmonary epithelial cells.

Am J Physiol Lung Cell Mol Physiol 2008 Jun 4;294(6):L1094-101. Epub 2008 Apr 4.

Pulmonary Division, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132-2406, USA.

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http://dx.doi.org/10.1152/ajplung.00318.2007DOI Listing
June 2008

Airway smooth muscle relaxation is impaired in mice lacking the p47phox subunit of NAD(P)H oxidase.

Am J Physiol Lung Cell Mol Physiol 2008 Jan 9;294(1):L139-48. Epub 2007 Nov 9.

Dept. of Pediatrics and Neonatal Perinatal Research Institute, Duke Univ. Medical Center, Rm. 302, Bell Bldg., Box 2994, Durham, NC 27710, USA.

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http://dx.doi.org/10.1152/ajplung.00384.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391573PMC
January 2008

The NOX on pulmonary hypertension.

Circ Res 2007 Aug;101(3):224-6

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http://dx.doi.org/10.1161/CIRCRESAHA.107.158246DOI Listing
August 2007

CPG15, a new factor upregulated after ischemic brain injury, contributes to neuronal network re-establishment after glutamate-induced injury.

J Neurotrauma 2007 Apr;24(4):722-31

State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1089/neu.2006.0174DOI Listing
April 2007

Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome.

Crit Care Med 2007 May;35(5):1369-75

Department of Pediatrics, Interdisciplinary Center of Clinical Research, Institute of Experimental Dermatology, University of Muenster, Germany.

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http://dx.doi.org/10.1097/01.CCM.0000262386.32287.29DOI Listing
May 2007

Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.

Am J Physiol Lung Cell Mol Physiol 2007 Jun 16;292(6):L1543-55. Epub 2007 Mar 16.

Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah Health Sciences Center and Veterans Administration Medical Center, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1152/ajplung.00430.2006DOI Listing
June 2007

High concentration of antioxidants N-acetylcysteine and mitoquinone-Q induces intercellular adhesion molecule 1 and oxidative stress by increasing intracellular glutathione.

J Immunol 2007 Feb;178(3):1835-44

Department of Internal Medicine, Pulmonary Division, University of Utah Health Science Center, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.4049/jimmunol.178.3.1835DOI Listing
February 2007

Role of TNFalpha in pulmonary pathophysiology.

Respir Res 2006 Oct 11;7:125. Epub 2006 Oct 11.

Pulmonary Division, Department of Internal Medicine, University of Utah Health Science Center, Salt Lake City, Utah 84132-4701, USA.

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http://dx.doi.org/10.1186/1465-9921-7-125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1613248PMC
October 2006

Cigarette smoke-induced Egr-1 upregulates proinflammatory cytokines in pulmonary epithelial cells.

Am J Respir Cell Mol Biol 2006 Sep 6;35(3):314-9. Epub 2006 Apr 6.

Department of Internal Medicine, Pulmonary Division, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0428OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643284PMC
September 2006

Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells.

Am J Physiol Lung Cell Mol Physiol 2006 Apr 14;290(4):L661-L673. Epub 2005 Oct 14.

Div. of Respiratory, Critical Care and Occupational Pulmonary Medicine, Wintrobe 701, Univ. of Utah Medical Center, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1152/ajplung.00269.2005DOI Listing
April 2006

Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development.

J Biol Chem 2005 Sep 20;280(37):32548-54. Epub 2005 Jul 20.

Department of Internal Medicine, Pulmonary Division, University of Utah Health Sciences Center, Salt Lake City, 84132, USA.

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http://dx.doi.org/10.1074/jbc.M502231200DOI Listing
September 2005

Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin.

J Biol Chem 2005 Oct 17;280(41):34966-73. Epub 2005 Jul 17.

Department of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City, Utah 84148, USA.

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http://dx.doi.org/10.1074/jbc.M502430200DOI Listing
October 2005

The role of reactive oxygen species in TNFalpha-dependent expression of the receptor for advanced glycation end products in human umbilical vein endothelial cells.

Biochim Biophys Acta 2005 Jun 7;1744(2):213-23. Epub 2005 Apr 7.

Department of Internal Medicine, Pulmonary Division, University of Utah Health Science Center, Salt Lake City, 84132-4701, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2005.03.007DOI Listing
June 2005

Differential effect of estrogen receptor alpha and beta agonists on the receptor for advanced glycation end product expression in human microvascular endothelial cells.

Biochim Biophys Acta 2005 Sep 12;1745(3):300-9. Epub 2005 Apr 12.

Pulmonary Division, Department of Internal Medicine, University of Utah Health Sciences Center, 30 North 1900 East, Room 4C104 SOM, Salt Lake City, UT 84132-4701, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2005.03.012DOI Listing
September 2005

The association between serum ferritin and uric acid in humans.

Free Radic Res 2005 Mar;39(3):337-42

National Health and Environmental Effects Research Laboratory, Office of Research and Development, Environmental Protection Agency, Research Triangle Park, NC 27711, USA.

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http://dx.doi.org/10.1080/10715760400026088DOI Listing
March 2005

The development of emphysema in cigarette smoke-exposed mice is strain dependent.

Am J Respir Crit Care Med 2004 Nov 28;170(9):974-80. Epub 2004 Jul 28.

Respiratory Division, Royal Victoria Hospital, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.200309-1270OCDOI Listing
November 2004

Characterization of proteins binding to E-box/Ku86 sites and function of Ku86 in transcriptional regulation of the human xanthine oxidoreductase gene.

J Biol Chem 2004 Apr 4;279(16):16057-63. Epub 2004 Feb 4.

Department of Internal Medicine, Division of Respiratory, Critical Care and Occupational Medicine, University of Utah Health Sciences Center and Veterans Affairs Medical Center, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1074/jbc.M305856200DOI Listing
April 2004

Human leukocyte elastase gene expression is regulated by PU.1 in conjunction with closely associated cytidine-rich and Myb binding sites.

Biochim Biophys Acta 2004 Jan;1676(1):104-11

Department of Internal Medicine, Division of Respiratory, Critical Care and Occupational Medicine, University of Utah Health Science Center and VA Medical Center, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1016/j.bbaexp.2003.10.005DOI Listing
January 2004

The role of endogenous NADPH oxidases in airway and pulmonary vascular smooth muscle function.

Antioxid Redox Signal 2003 Dec;5(6):751-8

Department of Internal Medicine, University of Utah School of Medicine, Medical Service, Salt Lake City, UT, USA.

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http://www.liebertpub.com/doi/10.1089/152308603770380052
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http://dx.doi.org/10.1089/152308603770380052DOI Listing
December 2003

Alpha1-antitrypsin determines the pattern of emphysema and function in tobacco smoke-exposed mice: parallels with human disease.

Am J Respir Crit Care Med 2002 Dec;166(12 Pt 1):1596-603

Respiratory Division, Royal Victoria Hospital, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.2202001DOI Listing
December 2002

Iron regulates xanthine oxidase activity in the lung.

Am J Physiol Lung Cell Mol Physiol 2002 Sep;283(3):L563-72

National Health and Environmental Effects Research Laboratory, Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

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http://dx.doi.org/10.1152/ajplung.00413.2000DOI Listing
September 2002

Future research directions in chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2002 Mar;165(6):838-44

Division of Lung Diseases, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892-7952, USA.

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http://dx.doi.org/10.1164/ajrccm.165.6.2108036DOI Listing
March 2002

NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2002 Apr;282(4):L782-95

Department of Internal Medicine, Cannon Research Center, Carolinas Medical Center, Charlotte, NC 28232, USA.

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http://www.physiology.org/doi/10.1152/ajplung.00206.2001
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http://dx.doi.org/10.1152/ajplung.00206.2001DOI Listing
April 2002