John R Bucher

John R Bucher

UNVERIFIED PROFILE

Are you John R Bucher?   Register this Author

Register author
John R Bucher

John R Bucher

Publications by authors named "John R Bucher"

Are you John R Bucher?   Register this Author

48Publications

630Reads

12Profile Views

Naturally complex: Perspectives and challenges associated with Botanical Dietary Supplement Safety assessment.

Food Chem Toxicol 2018 08 4;118:963-971. Epub 2018 Apr 4.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fct.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087675PMC
August 2018

Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".

Environ Health Perspect 2017 01;125(1):A8-A11

National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/EHP881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226707PMC
January 2017

Commemorating Toxicology at the National Institute of Environmental Health Sciences on the Occasion of Its 50th Anniversary.

Environ Health Perspect 2016 11;124(11):A192-A195

Division of the National Toxicology Program (NTP), Research Triangle Park, North Carolina USA.

View Article

Download full-text PDF

Source
http://ehp.niehs.nih.gov/EHP463
Publisher Site
http://dx.doi.org/10.1289/EHP463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089890PMC
November 2016

Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast™ High-Throughput Data.

Environ Health Perspect 2016 08 15;124(8):1141-54. Epub 2016 Mar 15.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1510456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977057PMC
August 2016

Bisphenol A, Bisphenol S, and 4-Hydro​xyphenyl 4-Isopro​oxyphenyl​sulfone (BPSIP) in Urine and Blood of Cashiers.

Environ Health Perspect 2016 Apr 25;124(4):437-44. Epub 2015 Aug 25.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1409427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824622PMC
April 2016

Pharmacokinetics of bisphenol A in humans following a single oral administration.

Environ Int 2015 Oct 24;83:107-15. Epub 2015 Jun 24.

National Cancer Institute, National Institutes of Health, Department of Health and Human Services, P.O. Box 12233, Mail Drop B2-01, Research Triangle Park, NC 27709, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.envint.2015.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545316PMC
October 2015

Comparative toxicity and carcinogenicity of soluble and insoluble cobalt compounds.

Toxicology 2015 Jul 17;333:195-205. Epub 2015 Apr 17.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2015.04.008DOI Listing
July 2015

IARC monographs: 40 years of evaluating carcinogenic hazards to humans.

Authors:
Neil Pearce Aaron Blair Paolo Vineis Wolfgang Ahrens Aage Andersen Josep M Anto Bruce K Armstrong Andrea A Baccarelli Frederick A Beland Amy Berrington Pier Alberto Bertazzi Linda S Birnbaum Ross C Brownson John R Bucher Kenneth P Cantor Elisabeth Cardis John W Cherrie David C Christiani Pierluigi Cocco David Coggon Pietro Comba Paul A Demers John M Dement Jeroen Douwes Ellen A Eisen Lawrence S Engel Richard A Fenske Lora E Fleming Tony Fletcher Elizabeth Fontham Francesco Forastiere Rainer Frentzel-Beyme Lin Fritschi Michel Gerin Marcel Goldberg Philippe Grandjean Tom K Grimsrud Per Gustavsson Andy Haines Patricia Hartge Johnni Hansen Michael Hauptmann Dick Heederik Kari Hemminki Denis Hemon Irva Hertz-Picciotto Jane A Hoppin James Huff Bengt Jarvholm Daehee Kang Margaret R Karagas Kristina Kjaerheim Helge Kjuus Manolis Kogevinas David Kriebel Petter Kristensen Hans Kromhout Francine Laden Pierre Lebailly Grace LeMasters Jay H Lubin Charles F Lynch Elsebeth Lynge Andrea 't Mannetje Anthony J McMichael John R McLaughlin Loraine Marrett Marco Martuzzi James A Merchant Enzo Merler Franco Merletti Anthony Miller Franklin E Mirer Richard Monson Karl-Cristian Nordby Andrew F Olshan Marie-Elise Parent Frederica P Perera Melissa J Perry Angela Cecilia Pesatori Roberta Pirastu Miquel Porta Eero Pukkala Carol Rice David B Richardson Leonard Ritter Beate Ritz Cecile M Ronckers Lesley Rushton Jennifer A Rusiecki Ivan Rusyn Jonathan M Samet Dale P Sandler Silvia de Sanjose Eva Schernhammer Adele Seniori Costantini Noah Seixas Carl Shy Jack Siemiatycki Debra T Silverman Lorenzo Simonato Allan H Smith Martyn T Smith John J Spinelli Margaret R Spitz Lorann Stallones Leslie T Stayner Kyle Steenland Mark Stenzel Bernard W Stewart Patricia A Stewart Elaine Symanski Benedetto Terracini Paige E Tolbert Harri Vainio John Vena Roel Vermeulen Cesar G Victora Elizabeth M Ward Clarice R Weinberg Dennis Weisenburger Catharina Wesseling Elisabete Weiderpass Shelia Hoar Zahm

Environ Health Perspect 2015 Jun 24;123(6):507-14. Epub 2015 Feb 24.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1409149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595PMC
June 2015

Translational cancer research: balancing prevention and treatment to combat cancer globally.

J Natl Cancer Inst 2015 Jan 16;107(1):353. Epub 2014 Dec 16.

Director's Office, Sections of Mechanisms of Carcinogenesis and Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France (CPW, ZH, RH, AS); National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA (JRB); Department of Pathology, Erasmus Medical Centre, Rotterdam, The Netherlands (BWDdJ); Department of Medical Epidemiology & Biostatistics, BioBanking & Molecular Resource Infrastructure, Karolinska Institute, Stockholm, Sweden (JD); Radiation Medicine Center, Karolinska Institute, Stockholm, Sweden (CvG); Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA (JDG); Department of Surgery and Cancer, Imperial College London, London, UK (EH); Danish Cancer Society Research Centre, Copenhagen, Denmark (JHO); Cancer Center Karolinska, Karolinska University Hospital Solna, Stockholm, Sweden (UR); Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan (TS); School of Public Health, University of California, Berkeley, CA, USA (MTS); Division of Preventive Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany (CU); Department of Epidemiology & Biostatistics, Imperial College London, London, UK (PV); Dalla Lana School of Public Health, University of Toronto, Toronto, Canada (JM).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/dju353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334834PMC
January 2015

The National Toxicology Program Web-based nonneoplastic lesion atlas: a global toxicology and pathology resource.

Toxicol Pathol 2014 ;42(2):458-60

1Division of the National Toxicology Program, National Institute of Environmental Health Sciences, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623313517304DOI Listing
September 2014

Systematic review and evidence integration for literature-based environmental health science assessments.

Environ Health Perspect 2014 Jul 22;122(7):711-8. Epub 2014 Apr 22.

Office of Health Assessment and Translation, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1307972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080517PMC
July 2014

A new approach to synergize academic and guideline-compliant research: the CLARITY-BPA research program.

Reprod Toxicol 2013 Sep 5;40:35-40. Epub 2013 Jun 5.

National Institute of Environmental Health Sciences/National Institutes of Health, Division of Extramural Research, Research Triangle Park, NC 27709, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reprotox.2013.05.010DOI Listing
September 2013

Improving the human hazard characterization of chemicals: a Tox21 update.

Environ Health Perspect 2013 Jul 19;121(7):756-65. Epub 2013 Apr 19.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1205784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701992PMC
July 2013

Regulatory forum opinion piece: Tox21 and toxicologic pathology.

Authors:
John R Bucher

Toxicol Pathol 2013 Jan 12;41(1):125-7. Epub 2012 Jun 12.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623312450632DOI Listing
January 2013

Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A.

Environ Health Perspect 2012 Dec 25;120(12):1640-4. Epub 2012 Sep 25.

National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Research Triangle Park, North Carolina 27709 , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1205330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548284PMC
December 2012

Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review.

Environ Health Perspect 2012 Jun 1;120(6):779-89. Epub 2012 Feb 1.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.1104597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385443PMC
June 2012

Commentary: update on animal models for NTP studies.

Toxicol Pathol 2010 Jan 17;38(1):180-1. Epub 2009 Dec 17.

Cellular and Molecular Pathology Branch, National Institute of Environmental Health Sciences/National Toxicology Program (NIEHS/NTP), Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0192623309356450DOI Listing
January 2010

A 21st century paradigm for evaluating the health hazards of nanoscale materials?

Toxicol Sci 2009 Aug 25;110(2):251-4. Epub 2009 May 25.

National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfp106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708598PMC
August 2009

Bisphenol A: where to now?

Authors:
John R Bucher

Environ Health Perspect 2009 Mar;117(3):A96-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.12492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661936PMC
March 2009

Influence of Helicobacter hepaticus infection on the chronic toxicity and carcinogenicity of triethanolamine in B6C3F1 mice.

Toxicol Pathol 2008 Oct 23;36(6):783-94. Epub 2008 Sep 23.

National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/0192623308322312
Publisher Site
http://dx.doi.org/10.1177/0192623308322312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719836PMC
October 2008

Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure.

Toxicology 2008 Feb 28;244(2-3):209-19. Epub 2007 Nov 28.

Toxicology Operations Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0300483X0700783
Publisher Site
http://dx.doi.org/10.1016/j.tox.2007.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683681PMC
February 2008

Toxicology. Transforming environmental health protection.

Science 2008 Feb;319(5865):906-7

National Human Genome Research Institute (NHGRI), National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1154619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679521PMC
February 2008

Conflicting views on chemical carcinogenesis arising from the design and evaluation of rodent carcinogenicity studies.

Environ Health Perspect 2008 Jan;116(1):130-5

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.9989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199296PMC
January 2008

alpha 2u-globulin nephropathy and renal tumors in national toxicology program studies.

Toxicol Pathol 2007 Jun;35(4):533-40

National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01926230701338941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2104517PMC
June 2007

A review of evidence from short-term studies leading to the prediction that diazoaminobenzene (1,3-diphenyltriazine) is a carcinogen.

J Appl Toxicol 2005 Nov-Dec;25(6):514-21

National Toxicology Program, National Institute of Environmental Health Sciences, P.O. Box 12233, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jat.1087DOI Listing
December 2006

Comparison of chronic toxicity and carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in 2-year bioassays in female Sprague-Dawley rats.

Mol Nutr Food Res 2006 Oct;50(10):934-44

Environmental Toxicology Program, National Institute of Environmental Health Sciences, Natinal Institutes of Health, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mnfr.200600031
Publisher Site
http://dx.doi.org/10.1002/mnfr.200600031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934421PMC
October 2006

Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds".

Environ Health Perspect 2005 Jan;113(1):43-8

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27705, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253708PMC
http://dx.doi.org/10.1289/ehp.7351DOI Listing
January 2005

DETERMINING DISEASE CAUSALITY FROM EXPERIMENTAL TOXICOLOGY STUDIES.

J Law Policy 2005 ;14(1):113-133

Ronald L. Melnick is Director of Special Programs, Environmental Toxicology Program (ETP), National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS); John R. Bucher is Deputy Director ETP, NTP/NIEHS.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391076PMC
January 2005

Human carcinogenic risk evaluation, Part V: The national toxicology program vision for assessing the human carcinogenic hazard of chemicals.

Toxicol Sci 2004 Dec 29;82(2):363-6. Epub 2004 Sep 29.

National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfh293DOI Listing
December 2004

Toxicology and carcinogenesis studies of dipropylene glycol in rats and mice.

Toxicology 2004 Nov;204(2-3):123-40

National Institute of Environmental Health Sciences, Mail Drop EC-35, 79 TW Alexander Drive, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2004.06.019DOI Listing
November 2004

Inhalation toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether in rats and mice.

Toxicology 2004 Jun;199(1):1-22

National Institute of Environmental Health Sciences, 79 Alexander Dr., Mail Drop EC-34, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tox.2003.12.020DOI Listing
June 2004

Toxicity characterization of environmental chemicals by the US National Toxicology Program: an overview.

Int J Hyg Environ Health 2003 Aug;206(4-5):437-45

National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S143846390470240
Publisher Site
http://dx.doi.org/10.1078/1438-4639-00240DOI Listing
August 2003

The National Toxicology Program rodent bioassay: designs, interpretations, and scientific contributions.

Authors:
John R Bucher

Ann N Y Acad Sci 2002 Dec;982:198-207

National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 22709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1749-6632.2002.tb04934.xDOI Listing
December 2002

Micronucleus induction in mice exposed to diazoaminobenzene or its metabolites, benzene and aniline: implications for diazoaminobenzene carcinogenicity.

Mutat Res 2002 Nov;521(1-2):201-8

National Institute of Environmental Health Sciences, 79 Alexander Drive, Mail Drop EC-34, Research Triangle Park, Triangle Park, NC 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1383-5718(02)00241-3DOI Listing
November 2002

Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice.

Toxicol Sci 2002 Jul;68(1):59-68

Environmental Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/68.1.59DOI Listing
July 2002