Publications by authors named "John Perentesis"

60Publications

Improved chemotherapy modeling with RAG-based immune deficient mice.

PLoS One 2019 20;14(11):e0225532. Epub 2019 Nov 20.

Division of Experimental Hematology and Cancer Biology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225532PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867639PMC
March 2020

Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy.

Int J Part Ther 2018 21;5(1):40-48. Epub 2018 Sep 21.

Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH, USA.

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http://dx.doi.org/10.14338/IJPT-18-00023.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871586PMC
September 2018

Viral surveillance using PCR during treatment of AML and ALL.

Pediatr Blood Cancer 2018 Jan 9;65(1). Epub 2017 Aug 9.

Cancer and Blood Diseases Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/pbc.26752DOI Listing
January 2018

Significant and Sustained Reduction in Chemotherapy Errors Through Improvement Science.

J Oncol Pract 2017 04 4;13(4):e329-e336. Epub 2017 Mar 4.

Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

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http://ascopubs.org/doi/10.1200/JOP.2017.020842
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http://dx.doi.org/10.1200/JOP.2017.020842DOI Listing
April 2017

Population pharmacokinetics of temsirolimus and sirolimus in children with recurrent solid tumours: a report from the Children's Oncology Group.

Br J Clin Pharmacol 2017 05 20;83(5):1097-1107. Epub 2016 Dec 20.

Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1111/bcp.13181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401981PMC
May 2017

A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.

Pediatr Blood Cancer 2017 03 22;64(3). Epub 2016 Sep 22.

Division of Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/pbc.26258DOI Listing
March 2017

Population pharmacokinetics of sirolimus in pediatric patients with neurofibromatosis type 1-Erratum.

Ther Drug Monit 2016 04 21;38(2):284. Epub 2016 Jan 21.

1Division of Pharmacy, Cincinnati Children's Hospital Medical Center 2Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center 3Department of Pediatrics, University of Cincinnati, College of Medicine 4Cancer & Blood Disease Institute, Division of Oncology, Cincinnati Children's Hospital Medical Center 5Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD 6Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1097/FTD.0000000000000275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956590PMC
April 2016

Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma.

Pediatr Blood Cancer 2015 Oct 7;62(10):1739-46. Epub 2015 Jul 7.

Cancer Center and Departments of Cell Biology & Biochemistry, Pediatrics and Medicine, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.

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http://dx.doi.org/10.1002/pbc.25594DOI Listing
October 2015

Increasing the efficiency of trial-patient matching: automated clinical trial eligibility pre-screening for pediatric oncology patients.

BMC Med Inform Decis Mak 2015 Apr 14;15:28. Epub 2015 Apr 14.

Cincinnati Children's Hospital Medical Center, Department of Biomedical Informatics, 3333 Burnet Avenue, MLC 7024, Cincinnati, OH, USA.

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http://dx.doi.org/10.1186/s12911-015-0149-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407835PMC
April 2015

Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a neurofibromatosis Clinical Trials Consortium phase II study.

Neuro Oncol 2015 Apr 14;17(4):596-603. Epub 2014 Oct 14.

Division of Oncology, Cincinnati Children's Hospital Medical Center, Cancer and Blood Diseases Institute, Cincinnati, Ohio (B.W., J.P.); Division of Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (E.S.); Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (A.V.); National Cancer Institute, Pediatric Oncology Branch, Bethesda, Maryland (B.C.W, E.D., P.W.); Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama (B.K.); Department of Preventitive Medicine, University of Alabama at Birmingham, Birmingham, Alabama (A.C.); Department of Neurology, Boston Children's Hospital, Boston, Massachusetts (N.U.); Department of Neurology, Washington University, St. Louis, Missouri (D.H.G.); Children's National Health System, Center for Neuroscience and Behavioral Medicine, Washington, DC (R.J.P.); Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (M.J.F.); Division of Genetics, Primary Children's Hospital, Salt Lake City, Utah (D.V.); Division of Neurology, The University of Chicago Medicine Comer Children's Hospital, Chicago, Illinois (J.T.).

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http://dx.doi.org/10.1093/neuonc/nou235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483073PMC
April 2015

Age-dependent changes in sirolimus metabolite formation in patients with neurofibromatosis type 1.

Ther Drug Monit 2015 Jun;37(3):395-9

*Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center; †Department of Pediatrics, College of Medicine, University of Cincinnati, OH; ‡iC42 Integrated Solutions in Clinical Research and Development, University of Colorado, Aurora; §Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD; ¶Division of Oncology, The Children's Hospital of Philadelphia; ‖Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia; **Division of Oncology, Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center; and ††Department of Pharmacology and Cell Biophysics, College of Medicine, University of Cincinnati, OH.

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http://dx.doi.org/10.1097/FTD.0000000000000130DOI Listing
June 2015

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.

Neuro Oncol 2014 May 4;16(5):707-18. Epub 2014 Feb 4.

Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland (B.W., E.D., A.G., P.W., S.M., E.F., F.B.); Cancer Therapy Evaluation Program, Investigational Drug Branch, National Cancer Institute, Bethesda, Maryland (J.W.); Biostatistics and Data Management Section, National Cancer Institute, Bethesda, Maryland (S.S.); Diagnostic Radiology Department, National Institutes of Health, Bethesda, Maryland (N.P.); The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (J.B., E.F., F.B.); Ann and Robert H. Lurie Children's Hospital, Chicago, Illinois (S.G.); Department of Genetics, University of Alabama at Birmingham, South Birmingham, Alabama (B.K.); Expert Image Analysis LC, Potomac, Maryland (J.S.); Dana-Farber/Children's Hospital Cancer Center, Boston, Massachusetts (M.K.); Cincinnati Children's Hospital, Cincinnati, Ohio (J.P.); Children's National Medical Center, Washington, DC (A.K.); US Army Medical Research and Material Command, Fort Detrick, Maryland (W.S.); Children's Hospital of Alabama, Birmingham, Alabama (A.R.).

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http://dx.doi.org/10.1093/neuonc/nou004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984559PMC
May 2014

Low dose decitabine in very high risk relapsed or refractory acute myeloid leukaemia in children and young adults.

Br J Haematol 2013 May 23;161(3):406-10. Epub 2013 Feb 23.

Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 452229, USA.

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http://dx.doi.org/10.1111/bjh.12268DOI Listing
May 2013

Children's Oncology Group's 2013 blueprint for research: adolescent and young adult oncology.

Pediatr Blood Cancer 2013 Jun 19;60(6):1055-8. Epub 2012 Dec 19.

Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, CA 90027-6016, USA.

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http://dx.doi.org/10.1002/pbc.24431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604044PMC
June 2013

Children's Oncology Group's 2013 blueprint for research: acute myeloid leukemia.

Pediatr Blood Cancer 2013 Jun 19;60(6):964-71. Epub 2012 Dec 19.

Children's Mercy Hospitals & Clinics, Kansas City, MO 64108, USA.

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http://dx.doi.org/10.1002/pbc.24432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605815PMC
June 2013

Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.

Clin Cancer Res 2012 Sep 18;18(18):5020-30. Epub 2012 Jul 18.

Divisions of Experimental Hematology and Cancer Biology, Oncology, and Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902639PMC
September 2012

Management of metabolic effects associated with anticancer agents targeting the PI3K-Akt-mTOR pathway.

J Clin Oncol 2012 Aug 9;30(23):2919-28. Epub 2012 Jul 9.

Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://ascopubs.org/doi/10.1200/JCO.2011.39.7356
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http://dx.doi.org/10.1200/JCO.2011.39.7356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410405PMC
August 2012

Tribute: the American Society of Pediatric Hematology/Oncology (ASPHO), 2011 Distinguished Career Award goes to Dr. William G. Woods.

Pediatr Blood Cancer 2011 Jun;56(6):895-6

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45230, USA.

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http://dx.doi.org/10.1002/pbc.23093DOI Listing
June 2011

Phase I study of paclitaxel with standard dose ifosfamide in children with refractory solid tumors: a Pediatric Oncology Group study (POG 9376).

Pediatr Blood Cancer 2009 Mar;52(3):346-50

Department of Hematology-Oncology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1002/pbc.21820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744894PMC
March 2009

Translocation (8;18;16)(p11;q21;p13). A new variant of t(8;16)(p11;p13) in acute monoblastic leukemia: case report and review of the literature.

Cancer Genet Cytogenet 2006 Feb;165(1):75-8

Division of Pathology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2005.10.017DOI Listing
February 2006

Parental exposure to medications and hydrocarbons and ras mutations in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.

Cancer Epidemiol Biomarkers Prev 2004 Jul;13(7):1230-5

Vanderbilt-Ingram Cancer Center and Vanderbilt Center for Health Services Research, Vanderbilt University, Nashville, Tennessee, USA.

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July 2004

Osteosarcoma in the first decade of life.

Med Pediatr Oncol 2003 Nov;41(5):480-3

Department of Pediatrics, Division of Epidemiology and Clinical Research, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1002/mpo.10403DOI Listing
November 2003

Results of treatment for metastatic osteosarcoma with neoadjuvant chemotherapy and surgery.

Clin Orthop Relat Res 2002 Apr(397):240-7

Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1097/00003086-200204000-00028DOI Listing
April 2002